Search results for "Porte"
showing 10 items of 1894 documents
Spanish validation of the Sexual Addiction Screening Test.
2018
Background and aims Sexual addiction is a pathological behavior characterized by a combination of excessive sexual desire and impaired ability to control it. Its incidence ranges between 1.2% and 32.2%, although this number may vary depending on the screening tool used. This wide variability is largely due to the use of non-validated instruments (e.g., structural validity relying on exploratory analyses, instruments translated without an additional validation process, or instruments validated in another format). To deal with these limitations, this study tested the psychometric properties of the Spanish paper-and-pencil and online versions of the Sexual Addiction Screening Test (SAST). Met…
Transporter (TAP)- and proteasome-independent presentation of a melanoma-associated tyrosinase epitope.
2000
The melanosomal protein tyrosinase is considered as a target of specific immunotherapy against melanoma. Two tyrosinase-derived peptides are presented in association with HLA-A2.1 [Wolfel et al., Eur. J. Immunol., 24, 759-764 (1994)]. Peptide 1-9 (MLLAVLYCL) is generated from the putative signal sequence. The internal peptide 369-377 is posttranslationally converted at residue 371, and its presentation is dependent on functional TAP transporters and proteasomes [Mosse et al., J. exp. Med.187, 37-48 (1998)]. Herein, we report on the processing and transport requirements for the signal sequence-derived peptide 1-9 that were studied in parallel to those for peptide 369-377. After infection of …
Supported ionic liquids. New recyclable materials for the L-proline-catalyzed aldol reaction
2006
New materials for L-proline recycling have been developed. These materials have been applied to the L-proline-catalyzed aldol reaction between acetone and several aldehydes. The L-proline has been supported on the surface of modified silica gels with a monolayer of covalently attached ionic liquid with or without additional adsorbed ionic liquid. Good yields and ee values, comparable with those obtained under homogeneous conditions, have been obtained especially with imidazolinium-modified and 4-methylpyridinium-modified silica gels. Moreover, these materials have been easily recovered by simple filtration and studies about their reuse have been carried out. These studies showed that these …
Ex-Ante Business Model Evaluation Methods: A Proposal of Improvement and Applicability
2019
[EN] Purpose: The purpose of this paper is to choose the best method for ex ante business model evaluation, improve it and provide a framework to put it into practice. Design/Methodology/Approach: After an in-depth review, we chose the best method for ex ante business model evaluation, improved this method, and applied it to a real case study in which business models had been proposed for a Sustainable Smart District project. Findings: We analysed existing ex ante business model evaluation methods, justifying our choice of the best one. We improved this key question-based method by combining classic management tools and a new, promising procedure. We finally found a strong tool to improve b…
Role of secondary transporters and phosphotransferase systems in glucose transport by Oenococcus oeni.
2011
ABSTRACT Glucose uptake by the heterofermentative lactic acid bacterium Oenococcus oeni B1 was studied at the physiological and gene expression levels. Glucose- or fructose-grown bacteria catalyzed uptake of [ 14 C]glucose over a pH range from pH 4 to 9, with maxima at pHs 5.5 and 7. Uptake occurred in two-step kinetics in a high- and low-affinity reaction. The high-affinity uptake followed Michaelis-Menten kinetics and required energization. It accumulated the radioactivity of glucose by a factor of 55 within the bacteria. A large portion (about 80%) of the uptake of glucose was inhibited by protonophores and ionophores. Uptake of the glucose at neutral pH was not sensitive to degradation …
Problems and Adaptive Functioning Reported by Adults in 17 Societies
2016
This study tested for similarities and differences across societies in self-ratings ofproblems, personal strengths, and aspects of adaptive functioning on the Adult Self-Report (ASR) for nonclinical samples of adults ages 18 to 59 in 17 societies (N 10,197). Results indicated considerable consistency across societies regarding meanratings on the ASR problem items. Most effect sizes (ESs) for societal differences inproblem scales were small (2?5%). Hierarchical linear modeling (HLM) analysesindicated that culture clusters and society accounted for small percentages of variancein Internalizing, Externalizing, and Total Problems scores, with most of the variationaccounted for by individual dif…
Taking into Account Patient Preferences: A Consensus Study on the Assessment of Psychological Dimensions Within Patient Preference Studies
2021
Selena Russo,1,2,* Dario Monzani,3,4,* Cathy Anne Pinto,5 Laura Vergani,3,4 Giulia Marton,3,4 Marie Falahee,6 Gwenda Simons,6 Chiara Whichello,7 Ulrik Kihlbom,8,* Gabriella Pravettoni3,4,* 1Department of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy; 2Discipline of Paediatrics, School of Women’s and Children’s Health, The University of New South Wales, Kensington, NSW, Australia; 3Applied Research Division for Cognitive and Psychological Science, IEO, European Institute of Oncology IRCCS, Milan, Italy; 4Department of Oncology and Hemato-oncology, University of Milan, Milan, Italy; 5Department of Pharmacoepidemiology, Merck & Co., Inc., Kenilwor…
Sport and social integration in images: sporting women against exclusion
2013
El deporte puede convertirse en un medio para mejorar las condiciones de vida de colectivos vulnerables. Si se integra en un proyecto de intervención con estos grupos, puede aportar un buen número de ventajas, desde las propias sensaciones placenteras por su práctica, hasta las ventajas más relacionadas con el crecimiento del capital social o de hábitos saludables y mejora de la forma física. En el artículo, se exponen algunos resultados de una investigación en la que se ha estudiado cómo se puede utilizar el deporte con mujeres en situaciones de riesgo de exclusión, cuáles son sus problemas de cara a la práctica deportiva, qué es lo que esta les puede aportar, cómo se podría desarrollar un…
L'interface homme-machine en commerce électronique : vers une création de lien social comme outil de positionnement stratégique
2005
International audience; Une étude qualitative textuelle tentera de démontrer qu'une entreprise peut créer une relation avec sa clientèle grâce à Internet, en comparant les réponses d'individus ayant consulté un site Internet sans lien social et un site sans lien social. Ensuite, une représentation visuelle de l'analyse textuelle sera effectuée à l'aide d'un carré sémiotique.
El debate cívico en la sociedad de hoy
2003
Reseña de Ignacio Ramonet sobre el libro coordinado por José Vidal-Beneyto "Hacia una sociedad civil global" (Taurus, 2003), que forma parte del programa de la Agencia Europea de la Cultura "Europa-Mundi".