Search results for "Positive"

Il contributo della religione e della spiritualità allo sviluppo positivo dei giovani. Una rassegna sistematica della letteratura

2020

La prospettiva teorica del Positive Youth Development (PYD) suggerisce come la religione e la spiritualità possano rappresentare risorse, ideologiche e sociali, capaci di sostenere percorsi di sviluppo positivo nei giovani. Considerato ciò, il presente lavoro ha rivisto sistematicamente la più recente letteratura, con l’obiettivo di studiare il contributo di tali risorse. È stata inizialmente interrogata la banca dati Scopus. Diciannove studi, pubblicati dal 2000 in poi e rispettanti i criteri stabiliti, sono stati inclusi nella rassegna. I risultati offrono indicazioni su quali siano le condizioni per le quali religione e spiritualità possono incentivare efficacemente lo sviluppo ottimale …

Existence of two positive solutions for anisotropic nonlinear elliptic equations

2021

This paper deals with the existence of nontrivial solutions for a class of nonlinear elliptic equations driven by an anisotropic Laplacian operator. In particular, the existence of two nontrivial solutions is obtained, adapting a two critical point results to a suitable functional framework that involves the anisotropic Sobolev spaces.

Existence Results for Periodic Boundary Value Problems with a Convenction Term

2020

By using an abstract coincidence point theorem for sequentially weakly continuous maps the existence of at least one positive solution is obtained for a periodic second order boundary value problem with a reaction term involving the derivative \(u'\) of the solution u: the so called convention term. As a consequence of the main result also the existence of at least one positive solution is obtained for a parameter-depending problem.

MR2641584 Joiţa, Maria On extremal covariant completely multi-positive linear maps. Proceedings of the Sixth Congress of Romanian Mathematicians. Vol…

2011

MR2806473 (2012f:47002) Hirasawa, Go(J-IBARE) A metric for unbounded linear operators in a Hilbert space. (English summary) Integral Equations Operat…

2012

Phenotypic and Immunometabolic Aspects on Stem Cell Memory and Resident Memory CD8+ T Cells

2022

The immune system, smartly and surprisingly, saves the exposure of a particular pathogen in its memory and reacts to the pathogen very rapidly, preventing serious diseases.Immunologists have long been fascinated by understanding the ability to recall and respond faster and more vigorously to a pathogen, known as “memory”.T-cell populations can be better described by using more sophisticated techniques to define phenotype, transcriptional and epigenetic signatures and metabolic pathways (single-cell resolution), which uncovered the heterogeneity of the memory T-compartment. Phenotype, effector functions, maintenance, and metabolic pathways help identify these different subsets. Here, we exam…

Effects of acute CPAP application on baroreflex control of heart rate during sleep in severe obstructive sleep apnea.

2006

Baroreflex control of heart rate during sleep (baroreflex sensitivity; BRS) has been shown to be depressed in obstructive sleep apnoea (OSA), and improved after treatment with continuous positive airway pressure (CPAP). Whether CPAP also acutely affects BRS during sleep in uncomplicated severe OSA is still debatable. Blood pressure was monitored during nocturnal polysomnography in 18 patients at baseline and during first-time CPAP application. Spontaneous BRS was analysed by the sequence method, and estimated as the mean sequence slope. CPAP did not acutely affect mean blood pressure or heart rate but decreased cardiovascular variability during sleep. Mean BRS increased slightly during CPAP…

An Online Metric Learning Approach through Margin Maximization

2011

This work introduces a method based on learning similarity measures between pairs of objects in any representation space that allows to develop convenient recognition algorithms. The problem is formulated through margin maximization over distance values so that it can discriminate between similar (intra-class) and dissimilar (inter-class) elements without enforcing positive definiteness of the metric matrix as in most competing approaches. A passive-aggressive approach has been adopted to carry out the corresponding optimization procedure. The proposed approach has been empirically compared to state of the art metric learning on several publicly available databases showing its potential bot…

Skewness in individual stocks at different investment horizons

2002

Abstract This paper examines the (a)symmetry of several individual stock returns at different investment horizons: daily, weekly and monthly. While some asymmetries are observed in daily returns, they disappear almost completely in weekly and monthly returns. The explanation for this fact lies in the convergence to normality that takes place when the investment horizon increases. These features allow one to question several financial models; in particular, they question the preference for positive skewness as a factor for investments in stock markets.

Dacarbazine-mediated upregulation of NKG2D ligands on tumor cells activates NK and CD8 T cells and restrains melanoma growth.

2013

International audience; Dacarbazine (DTIC) is a cytotoxic drug widely used for melanoma treatment. However, the putative contribution of anticancer immune responses in the efficacy of DTIC has not been evaluated. By testing how DTIC affects host immune responses to cancer in a mouse model of melanoma, we unexpectedly found that both natural killer (NK) and CD8(+) T cells were indispensable for DTIC therapeutic effect. Although DTIC did not directly affect immune cells, it triggered the upregulation of NKG2D ligands on tumor cells, leading to NK cell activation and IFNγ secretion in mice and humans. NK cell-derived IFNγ subsequently favored upregulation of major histocompatibility complex cl…