Search results for "Poster"
showing 10 items of 679 documents
2016
The negative interpretation of body sensations (e.g., as sign of a severe illness) is a crucial cognitive process in pathological health anxiety (HA). However, little is known about the nature and the degree of automaticity of this interpretation bias. We applied an implicit association test (IAT) in 20 subjects during functional magnetic resonance imaging (fMRI) to investigate behavioral and neural correlates of implicit attitudes towards symptom words. On the behavioral level, body symptom words elicited strong negative implicit association effects, as indexed by slowed reaction times when symptom words were paired with the attribute “harmless” (incongruent condition) relative to a contro…
Probabilistic cross-validation estimators for Gaussian process regression
2018
Gaussian Processes (GPs) are state-of-the-art tools for regression. Inference of GP hyperparameters is typically done by maximizing the marginal log-likelihood (ML). If the data truly follows the GP model, using the ML approach is optimal and computationally efficient. Unfortunately very often this is not case and suboptimal results are obtained in terms of prediction error. Alternative procedures such as cross-validation (CV) schemes are often employed instead, but they usually incur in high computational costs. We propose a probabilistic version of CV (PCV) based on two different model pieces in order to reduce the dependence on a specific model choice. PCV presents the benefits from both…
A posteriori error majorants of the modeling errors for elliptic homogenization problems
2013
In this paper, we derive new two-sided a posteriori estimates of the modeling errors for linear elliptic boundary value problems with periodic coefficients solved by homogenization. Our approach is based on the concept of functional a posteriori error estimation. The estimates are obtained for the energy norm and use solely the global flux of the non-oscillatory solution of the homogenized model and solution of a boundary value problem on the cell of periodicity.
A posteriori modelling-discretization error estimate for elliptic problems with L ∞-Coefficients
2017
We consider elliptic problems with complicated, discontinuous diffusion tensor A0. One of the standard approaches to numerically treat such problems is to simplify the coefficient by some approximation, say Aϵ, and to use standard finite elements. In [19] a combined modelling-discretization strategy has been proposed which estimates the discretization and modelling errors by a posteriori estimates of functional type. This strategy allows to balance these two errors in a problem adapted way. However, the estimate of the modelling error was derived under the assumption that the difference A0 - Aϵ becomes small with respect to the L∞-norm. This implies in particular that interfaces/discontinui…
P463 COVID-19 vaccination willingness and hesitancy in patients with Inflammatory Bowel Diseases (IBD): analysis of determinants in a national survey…
2021
Abstract Background Vaccine hesitancy, the delay in acceptance or refusal of vaccination despite its availability, represents a threat to the diffusion and lethality of infectious diseases. COVID-19 vaccination has been recommended by national and international organizations in patients with Inflammatory Bowel Diseases (IBD). The aim of the study was to evaluate COVID-19 vaccine willingness and hesitancy in a population of Italian patients with IBD, and their determinants. Methods In February 2021 an online questionnaire focused on COVID-19 vaccine was proposed to a representative sample of Italian IBD patients. Socio-demographic characteristics, IBD features, lifestyle, perception of COVID…
Synaptic scaling generically stabilizes circuit connectivity
2011
Neural systems regulate synaptic plasticity avoiding overly strong growth or shrinkage of the connections, thereby keeping the circuit architecture operational. Accordingly, several experimental studies have shown that synaptic weights increase only in direct relation to their current value, resulting in reduced growth for stronger synapses [1]. It is, however, difficult to extract from these studies unequivocal evidence about the underlying biophysical mechanisms that control weight growth. The theoretical neurosciences have addressed this problem by exploring mechanisms for synaptic weight change that contain limiting factors to regulate growth [2]. The effectiveness of these mechanisms i…
Osseotite caricati a due mesi nei settori posteriori del mascellare superiore: controllo a 2 anni di due casi clinici
2003
Aim Acid etched surface implants determine high clinical success rates, but little information is available about early loading in the posterior region of the maxilla, area at risk of failure. The aim of this work is to present two case reports of oral rehabilitation through acid etched surface implants (Osseotite, Implant Innovations - 3i, West Palm Beach, FL) loaded two months after insertion in the posterior maxilla. Materials and methods The success of Osseotite implants was assessed 12 and 24 months after prosthetic loading according to Albrektsson et al. criteria (1986). Results No clinical or radiographic signs of implant failure were observed during the two years follow-up. Conclusi…
First experience of the AML-Berlin-Frankfurt-Münster group in pediatric patients with standard-risk acute promyelocytic leukemia treated with arsenic…
2017
Recently, studies in adults with acute promyelocytic leukemia (APL) showed high cure rates in low-risk patients treated with all-trans retinoid acid (ATRA) and arsenic trioxide (ATO), while toxicities were significantly reduced compared to the standard treatment with ATRA and chemotherapy. Here we report about first experience with 11 pediatric patients with low-risk APL treated with ATRA and ATO. All patients stayed in molecular remission. All suffered from hyperleukocytosis. Two patients experienced reversible severe side effects. One suffered from osteonecroses at both femurs, seizures, as well as posterior reversible encephalopathy syndrome, the other patient had an abducens paresis.
Adaptive dual control in one biomedical problem
2003
In this paper, the following biomedical problem is considered. People are subjected to a certain chemotherapeutic treatment. The optimal dosage is the maximal dose for which an individual patient will have toxicity level that does not cross the allowable limit. We discuss sequential procedures for searching the optimal dosage, which are based on the concept of dual control and the principle of optimality. According to the dual control theory, the control has two purposes that might be conflicting: one is to help learning about unknown parameters and/or the state of the system (estimation); the other is to achieve the control objective. Thus the resulting control sequence exhibits the closed…