Search results for "Praxi"

The still under-investigated role of cognitive deficits in PML diagnosis

2017

Background: Despite cognitive deficits frequently represent the first clinical manifestations of Progressive Multifocal Leukoencephalopathy (PML) in Natalizumab-treated MS patients, the importance of cognitive deficits in PML diagnosis is still under-investigated. The aim of the current study is to investigate the cognitive deficits at PML diagnosis in a group of Italian patients with PML. Methods: Thirty-four PML patients were included in the study. The demographic and clinical data, the lesion load and localization, and the longitudinal clinical course was compared between patients with (n = 13) and without (n = 15) cognitive deficit upon PML suspicion (the remaining six patients were asy…

Opettaja tulevaisuuden taitojen edistäjänä : "jos haluat opettaa noita taitoja, sinun on ensin hallittava ne itse"

2013

El derecho como dogma en la forma etico-politico liberal. Otra lectura desde el realismo critico de E. Mounier: la persona como fundamento ético de l…

2019

Resumen: El realismo crítico personalista plantea una nueva idea de juridicidad. Reclama frente a la escisión radical entre teoría y praxis jurídica, entre lo axiológico y lo normativo, entre la realidad y lo objetivo, que esgrime la argumentación kelseniana, una instancia crítica para el derecho positivo: la existencia de la persona humana concreta, (que hace y vive la historia), como fundamento inmediato de todo lo jurídico. Si partimos de la base de que siendo la teoría general del derecho una invención moderna, hasta su culminación en Kelsen, ¿por qué no admitir que pueda ser matizada por otros marcos axiológicos y cognitivos, también modernos, descuidados desde entonces por esa concepc…

Par aptiekas stikla labvērtības noteikšanu

1933

Kopsavilkums vācu valodā.

Rol del perito psicólogo en el ámbito judicial

2008

In the field of Justice, a psychologist acts as a Psychology Expert and assists the Judge by supplying psychological techniques within a frame which is different from the clinic one. In this environment, the role of the psychologist is to diagnose and evaluate the psychological harm a person could have suffered as a consequence of a harmful event for example an accident, so that the victim may receive the corresponding money compensation. A psychology expert also acts in case of minor guardianship, divorce, mala praxis etc. Our proposal is to continue investigating in order to re-define the concept of psychological harm and to design new tables for determining the harm percentage.

Encoding of human action in Broca's area.

2009

International audience; Broca's area has been considered, for over a century, as the brain centre responsible for speech production. Modern neuroimaging and neuropsychological evidence have suggested a wider functional role is played by this area. In addition to the evidence that it is involved in syntactical analysis, mathematical calculation and music processing, it has recently been shown that Broca's area may play some role in language comprehension and, more generally, in understanding actions of other individuals. As shown by functional magnetic resonance imaging, Broca's area is one of the cortical areas activated by hand/mouth action observation and it has been proposed that it may …

Upper and lower face apraxia: role of the right hemisphere.

2000

The aim of this study was to evaluate face apraxia in left- and right-hemisphere-damaged patients both in the acute and chronic stage of their disease. Two newly devised tests that assess movements of the upper and lower face districts were employed. On the whole, the proportion of left-hemisphere-damaged patients showing face apraxia were 46 and 68% for upper and lower face, respectively. A substantial proportion of right-hemisphere-damaged patients also showed face apraxia, i.e. 44% upper face and 38% lower face. Concomitant variables such as general severity, locus of lesion, language or visuo-spatial impairments, presence of neglect, interval from stroke, peculiarity of clusters of item…

The impurity of praxis : Arendt and Agamben

2023

AbstractIf politics is understood as a foundational and open-ended activity, a general problem that arises from such a framing concerns the question of how to sustain the possibility of continuous openings without converting action into permanence and closure. In this article, we approach this problematic by treating Hannah Arendt as an exemplary figure in the current of political thought that emphasizes the indeterminate nature of action. We focus more specifically on how Arendt addressed the question of sustaining action by exploring the role of forgiveness, promises, divided power, and principles of action in her thought. While we show that the task of sustaining the indeterminacy of act…

Using tools effectively despite defective hand posture: A single-case study.

2019

Apraxia, a cognitive disorder of motor control, can severely impair transitive actions (object-related) and may lead to action errors (e.g., rubbing a hammer on a nail instead of pounding it) and hand posture errors (e.g., grasping a tool in a wrong way). Here, we report a rare observation of a left-handed patient, left-lateralized for language, who developed a severe apraxia following a right brain lesion. Interestingly the patient showed a significant number of hand posture errors, while she perfectly demonstrated the actual use of tools. This case stressed the predictions made by the current theories of tool use. According to the manipulation-based approach, the hand posture errors shoul…

Senataxin defective in ataxia oculomotor apraxia type 2 is involved in the defence against oxidative DNA damage

2007

Adefective response to DNA damage is observed in several human autosomal recessive ataxias with oculomotor apraxia, including ataxia-telangiectasia. We report that senataxin, defective in ataxia oculomotor apraxia (AOA) type 2, is a nuclear protein involved in the DNA damage response. AOA2 cells are sensitive to H2O2, camptothecin, and mitomycin C, but not to ionizing radiation, and sensitivity was rescued with full-length SETX cDNA. AOA2 cells exhibited constitutive oxidative DNA damage and enhanced chromosomal instability in response to H2O2. Rejoining of H2O2-induced DNA double-strand breaks (DSBs) was significantly reduced in AOA2 cells compared to controls, and there was no evidence fo…