Search results for "Pregnancy."
showing 10 items of 1965 documents
Impact on ICSI outcomes of adding 24 h of in vitro culture before testicular sperm freezing: a retrospective study.
2015
To compare sperm parameters and intracytoplasmic sperm injection (ICSI) outcomes for testicular spermatozoa frozen on the day of the biopsy (DO) with those frozen after 24 h of in vitro culture (D1).In this retrospective study, from 1999 to 2012, forty-nine azoospermic patients were included to compare sperm (motility and viability) and outcomes (fertilization (FR), implantation (IR), pregnancy (PR) and delivery rates (DR)).The in vitro culture increased total motility (+2.8 %, p = 0.0161) but decreased viability (-8.3 %, p = 0.007). After 24 h of culture, the post-thaw changes in motility and viability were not significant. Twenty-six couples underwent ICSI: thirty-four ICSI were performed…
Interrelationship between reproductive hormones and acute phase proteins during estrous cycle and pregnancy in Spanish purebred broodmares
2021
Highlights • Steroid hormones and acute phase proteins in cyclic and pregnant mares were evaluated. • SAA and CRP did not discriminate cyclic and pregnant mares. • Pregnancy induced a limited acute phase response in Spanish purebred mares. • SAA, Hp and CRP were independent of E1 and P4 dynamics during pregnancy.
Depressive effect of LHRH on the numbers of "synaptic" ribbons and spherules in the pineal gland of diestrous rats.
1983
Previous studies have shown that LHRH or LHRH-like substances are present in the pineal gland. In order to investigate whether exogenous LHRH may affect the pineal gland, in the present study the effects of a single dose of LHRH (1 microgram, i.p.) on pineal "synaptic" ribbons and spherules as well as serum melatonin levels were examined in diestrous Wistar rats. One hour after the injection both ribbons and spherules exhibited a statistically significant decrease in number. Serum melatonin levels were not affected. It is concluded that humoral feedback mechanisms may exist between the hypothalamus and the pineal gland.
Ovarian size and blood flow in women with polycystic ovary syndrome (PCOS) and their correlations with some endocrine parameters
2005
Objective: To determine how common polycystic ovarian morphology may be in women given the clinical diagnosis of polycystic ovary syndrome (PCOS) based on chronic anovulation and hyperandrogenism and whether certain hormonal factors correlate with ovarian morphology and blood flow. Design: Prospective study. Setting: Two academic endocrinology centers in Italy. Patient(s): Three hundred twenty-six women with PCOS and 50 age-matched and weight-matched ovulatory women. Intervention(s): Ultrasound assessment of ovarian morphology in patients and controls and ovarian blood flow and fasting hormone levels in a subset of 50 patients and matched controls. Main Outcome Measure(s): Ovarian morpholog…
Guidelines for biomarker discovery in endometrium: correcting for menstrual cycle bias reveals new genes associated with uterine disorders
2021
Abstract Transcriptomic approaches are increasingly used in reproductive medicine to identify candidate endometrial biomarkers. However, it is known that endometrial progression in the molecular biology of the menstrual cycle is a main factor that could affect the discovery of disorder-related genes. Therefore, the aim of this study was to systematically review current practices for considering the menstrual cycle effect and to demonstrate its bias in the identification of potential biomarkers. From the 35 studies meeting the criteria, 31.43% did not register the menstrual cycle phase. We analysed the menstrual cycle effect in 11 papers (including 12 studies) from Gene Expression Omnibus: t…
Farmaceitu un grūtnieču informētība par zāļu un vitamīnu ietekmi uz jaundzimušo veselību
2019
Maģistra darba mērķis bija noskaidrot farmaceitu un grūtnieču informētības līmeni par dažādu medikamentu un vitamīnu lietošanas drošumu bērna gaidību laikā. Vidēji farmaceitu zināšanas par dažādu aktīvo vielu lietošanas drošumu grūtniecības 1. trimestrī novērtējām ar 4,49 punktiem no 14 iespējamiem, izvēloties atbilstošākos atbilžu variantus. Tālākizglītības pasākumi par medikamentozo aprūpi grūtniecības laikā būtu vērtīgi farmaceitu praksei aptiekā (92,41% respondenti tā domā). 72,15% nav apmeklējuši šāda tipa tālākizglītības pasākumus pēc mācību iestādes absolvēšanas. 93,2% aptaujāto sieviešu uzskatīja, ka grūtniecības 1.trimestra laikā varētu būt bīstami lietot medikamentus, bet tikai 32…
Reply of the Authors: Hysteroscopic resection of the uterine septum: is it always a necessity?
2009
[No abstract available]
Conservative Management of Atypical Endometrial Hyperplasia and Early Endometrial Cancer in Childbearing Age Women.
2022
Total hysterectomy and bilateral adnexectomy is the standard treatment for atypical endometrial hyperplasia and early-stage endometrial cancer. However, the recommended surgical treatment precludes future pregnancy when these conditions are diagnosed in women in their fertile age. In these patients, fertility-sparing treatment may be feasible if the desire for childbearing is consistent and specific conditions are present. This review summarizes the available evidence on fertility-sparing management for atypical endometrial hyperplasia and early-stage endometrial cancer. Historically, oral progestins have been the mainstay of conservative management for atypical endometrial hyperplasia and …
Prolonging in utero-like oxygenation after birth diminishes oxidative stress in the lung and brain of mice pups☆
2013
Background Fetal-to-neonatal transition is associated with oxidative stress. In preterm infants, immaturity of the antioxidant system favours supplemental oxygen-derived morbidity and mortality. Objectives To assess if prolonging in utero-like oxygenation during the fetal-to-neonatal transition limits oxidative stress in the lung and brain, improving postnatal adaptation of mice pups. Material and methods Inspiratory oxygen fraction (FiO2) in pregnant mice was reduced from 21% (room air) to 14% (hypoxia) 8–12 h prior to delivery and reset to 21% 6–8 h after birth. The control group was kept at 21% during the procedure. Reduced (GSH) and oxidized (GSSG) glutathione and its precursors [γ-glut…