Search results for "Premises"
showing 10 items of 10 documents
Clinical benefit of vedolizumab on articular manifestations in patients with active spondyloarthritis associated with inflammatory bowel disease.
2017
Vedolizumab (VDZ) is a new biological agent which was recently approved for the treatment of inflammatory bowel disease (IBD)1 following the good clinical responses reported by clinical trials for both Crohn's disease2 and ulcerative colitis.3 However, the effects of VDZ on extraintestinal manifestations were not reported in these trials, and the ‘real life’ experience is still limited. On these premises, we read with interest the recent work by Varkas et al 4 reporting a series of five patients with IBD who were treated with VDZ and promptly developed new onset or exacerbation of spondyloarthritis (SpA), irrespective of the response to treatment on intestinal symptoms. Although the hypothe…
Recurrent pathologies in recently built schools in Palermo,
2006
This topic concerns the most significant pathologies noticed in the facilities being used as schools, which were built in Palermo in the last three decades. Many among these facilities already have undergone major restoration works, while the others are in poor conditions, which remarkably compromise the quality of their utilization. Sober elegance and safety are particularly important whenever a facility is to function as a school, especially if we consider the type of users and the ways of utilization. In order to achieve such goal, it is fundamental to analyse the most frequent pathologies, relating them to their causes, so as to have the tools for correcting previous errors and prevent …
Radiation response non-invasively imaged by [18F]FDG-PET predicts local tumor control and survival in advanced oral squamous cell carcinoma
2003
It is a major challenge to preoperatively identify patients who will profit from surgery of advanced oral cancer. In multimodality therapy, response to neoadjuvant radiation correlates to treatment success. Hence, for preoperative decisions, assessment of treatment response is required. Therefore, we analysed the prognostic significance of glucose metabolism after preoperative radiotherapy. [(18)F]FDG-PET investigations were performed for re-staging 35 patients after neoadjuvant radiotherapy (36Gy) immediately prior to tumor resection. Emission and transmission measurements were obtained and SUV's were calculated for the sites of maximum [(18)F]FDG-uptake. Subpopulations of "low" (SUV4) and…
Differential expression levels of urokinase-type plasminogen activator and cathepsin D in locally advanced laryngeal squamous cell carcinoma: Clinica…
2002
The expression levels and the prognostic impact of urokinase-type plasminogen activator (uPA) and cathepsin D (CD) were evaluated in patients with locally advanced laryngeal squamous cell carcinoma (LSCC). uPA and CD protein levels were determined by immunoluminometric or immunoenzymatic assays in the cytosol of paired sets of tumor tissues and corresponding adjacent normal mucosa (NLM) from 57 patients with stage III/IV LSCC and were correlated with a number of clinicobiological parameters of this tumor including anatomical site, tumor grade, nodal status, clinical stage, DNA ploidy, proliferation rate, and patient outcome. Median uPA levels were significantly higher in LSCC than in NLM (…
Combined use of antifibrinolytics and activated prothrombin complex concentrate (aPCC) is not related to thromboembolic events in patients with acqui…
2019
Antifibrinolytics combined with aPCC are not routinely administered to patients with acquired hemophilia A due to increased thrombotic risk. This association normalizes clot stability, and improves the efficacy of therapy, but can increase the risk of severe side effects. Due to these premises it has always raised doubts and perplexities in the clinics. We now report the data of the "FEIBA® on acquired haemophilia A Italian Registry (FAIR Registry)", a retrospective-prospective study that included 56 patients. This is the first study that assessed the clinical response of the combination of aPCC and antifibrinolytic agents in patients with acquired haemophilia A. A total of 101 acute bleeds…
Compliance of IEEE 802.22 WRAN for field area network in smart grid
2016
Distributed power system network is going to be complex, and it will require high-speed, reliable and secure communication systems for managing intermittent generation with coordination of centralised power generation, including load control. Cognitive Radio (CR) is highly favourable for providing communications in Smart Grid by using spectrum resources opportunistically. The IEEE 802.22 Wireless Regional Area Network (WRAN) having the capabilities of CR use vacant channels opportunistically in the frequency range of 54 MHz to 862 MHz occupied by TV band. A comprehensive review of using IEEE 802.22 for Field Area Network in power system network using spectrum sensing (CR based communication…
Contamination of a hospital plumbing system by persister cells of a copper-tolerant high-risk clone of Pseudomonas aeruginosa
2019
Abstract Background Pseudomonas aeruginosa (PA) is an important opportunistic pathogen that thrives best in the distal elements of plumbing and waste-water systems. Although nosocomial outbreaks of PA have been associated with water sources, the role of the plumbing system of healthcare premises as a reservoir for this pathogen is still unclear. Materials and methods We collected water samples from 12 technical areas, distant from any medical activity, in a teaching hospital in France once a week for 11 weeks. We used a method that resuscitates persister cells because of the nutrient-poor conditions and the presence of inhibitors (e.g. chlorine and copper ions). Briefly, water was sampled i…
The premises of the evolution and development of firm competences in strategic management
2021
Purpose: The aim of the article is to identify the premises of the evolution and development of firm competences in strategic management. Design/methodology/approach: The article indicates the key role of competences in strategic management. An extensive literature review and an identification approach were used. Findings: Competences may significantly affect the achievement of the expected market and economic outcomes, as well as building a long-term competitive advantage of a firm. Practical implications: The results of the research presented in the article show the significant importance of the firm competences in strategic management and business practice. Originality/value: The most im…
COMPOSITE SYNERGY OF SERVICES - A NEW CONCEPT CONCERNING SERVICES
2013
The current paper addresses the dynamics of the service sector in Romania, from the perspective of a new concept, namely the "composite synergy of services". The main points of the paper approach the fact that direct and indirect investments in the service sector create a synergic and composite effect on the development of the economy, as a whole, in Romania. The paper aims to be a prequel to a mathematical and economic demonstration of the existence of the composite synergy of services, laying the theoretical foundations of the concept and underlining the premises for its existence.
Bibliotēku iekārtojuma atbilstība Bibliotēku likumā noteiktajām prasībām
2016
Bakalaura darba „Bibliotēku iekārtojuma atbilstība Bibliotēku likumā noteiktajām prasībām” mērķis ir noskaidrot, vai publisko bibliotēku iekārtojums atbilst Latvijā noteiktiem normatīviem un Bibliotēku likumam. Lai realizētu bakalaura darbā izvirzīto mērķi, tika veikts jaukta tipa pētījums, kurā ir izmantotas kvalitatīvās un kvantitatīvās datu vākšanas metodes - dokumentu analīze, novērošana un daļēji strukturētā intervija. Iegūtie dati tiek analizēti no pragmatisma teorijas viedokļa. Pētījumā iegūtie rezultāti noved pie secinājumiem, ka bibliotēku iekārtojumā ir daļēji ievērotas normatīvajos dokumentos noteiktās prasības.