Search results for "Preservation"

showing 10 items of 484 documents

A newin vitroapproach for the simultaneous determination of phase I and phase II enzymatic activities of human hepatocyte preparations

2007

Primary hepatocytes are still the best qualified in vitro system to anticipate drug metabolism in man. Recent advances in hepatocytes cryopreservation have notably increased their use not only for drug metabolism studies, but also for other applications such as cell transplantation. Evaluation of the drug-metabolizing competence of each hepatocytes preparation is needed. To date, the metabolic characterization of hepatocytes preparations relies on the assessment of phase I activities and the role of phase II enzymes receives little attention. A novel approach for the rapid assessment of the metabolic functionality of hepatocytes has been developed. A five-probe cocktail was used to simultan…

chemistry.chemical_classificationSpectrometry Mass Electrospray IonizationSulfotransferaseCYP3A4Organic ChemistryTandem mass spectrometryMetabolic Detoxication Phase IICryopreservationIn vitroAnalytical ChemistryGlucuronidaseEnzymeCytochrome P-450 Enzyme SystemBiochemistrychemistryTandem Mass SpectrometryHepatocytesHumansMetabolic Detoxication Phase IGlucuronosyltransferaseSulfotransferasesCells CulturedChromatography High Pressure LiquidSpectroscopyDrug metabolismRapid Communications in Mass Spectrometry
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Steviol Glycosides Stability after Pulsed Electric Technologies and Ultrasounds Treatments in Fruit Juice Blend Sweetened with Stevia rebaudiana

2016

Stevia rebaudiana bartoni due to its high content in steviol glycosides and the ability to serve as a natural antimicrobial to complement the effectiveness of pulsed electric technologies for food preservation, has been used more frequently to improve sensorial properties of liquid foods.

chemistry.chemical_classificationStevia rebaudianachemistry.chemical_compoundchemistrydigestive oral and skin physiologyFood preservationGlycosideFruit juiceSteviolFood science
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Fluorescence and color as markers for the Maillard reaction in milk–cereal based infant foods during storage

2007

Abstract Free and total fluorescence compounds and color formation were measured in three different milk–cereal based infant foods stored at 25, 30 and 37 °C for 9 months to evaluate the advanced and final stages of the Maillard reaction. Milk–cereal infant foods containing honey (B) or fruits (C) had fluorescent values higher than sample (A) without them. This difference could be ascribed to the higher monosaccharide (fructose and/or glucose) content of (B) and (C), which could increase susceptibility to the Maillard reaction. However, for color increase (ΔE), no significant differences (p

chemistry.chemical_classificationdigestive oral and skin physiologyFood preservationfood and beveragesFructoseGeneral MedicineFluorescenceAnalytical Chemistrychemistry.chemical_compoundMaillard reactionsymbols.namesakechemistrysymbolsMonosaccharideColor formationFood scienceFood ScienceFood Chemistry
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Proyecto: cámara de conservación de libros para la Biblioteca Histórica de la Universitat de València

2017

Las dificultades para conseguir unas condiciones ambientales óptimas para la conservación de nuestro patrimonio bibliográfico y el elevado consumo energético necesario para mantenerlas han sido algunas de las premisas que nos han llevado a la proyección y realización de esta cámara de conservación. En ella se ha creado un espacio libre de influencia exterior que facilita la obtención de un clima adecuado y estable, con un consumo mínimo de energía, en el que se controlan los principales factores de degradación ambiental: temperatura y humedad precisas y estables, así como un control minucioso de la contaminación atmosférica y biológica; todo ello dirigido a aumentar la esperanza de vida de …

control clima bibliotecasclimate control librariesair renewalrenovación aireheritage preservationconservación patrimonio bibliográfico
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Impact on ICSI outcomes of adding 24 h of in vitro culture before testicular sperm freezing: a retrospective study.

2015

To compare sperm parameters and intracytoplasmic sperm injection (ICSI) outcomes for testicular spermatozoa frozen on the day of the biopsy (DO) with those frozen after 24 h of in vitro culture (D1).In this retrospective study, from 1999 to 2012, forty-nine azoospermic patients were included to compare sperm (motility and viability) and outcomes (fertilization (FR), implantation (IR), pregnancy (PR) and delivery rates (DR)).The in vitro culture increased total motility (+2.8 %, p = 0.0161) but decreased viability (-8.3 %, p = 0.007). After 24 h of culture, the post-thaw changes in motility and viability were not significant. Twenty-six couples underwent ICSI: thirty-four ICSI were performed…

endocrine systemUrologymedicine.medical_treatmentCultureMotilityICSICryopreservationIntracytoplasmic sperm injectionAndrologyIssuesHuman fertilizationBiopsyFreezingmedicinereproductive and urinary physiologyTesticular spermOutcomePregnancymedicine.diagnostic_testbusiness.industryurogenital systemRetrospective cohort studyCongélationmedicine.diseaseSpermReproductive MedicineSpermatozoïde testiculairebusinessResearch ArticleBasic and clinical andrology
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Prolactin supplementation to culture medium improves beta-cell survival

2010

OBJECTIVES.: Recent studies demonstrated that prolactin (PRL) has beneficial effects on β cells for islet transplantation. We examined the effect of human recombinant PRL (rhPRL) supplementation to the culture media to determine its potential use in the context of clinical islet transplantation. MATERIALS AND METHODS.: Each human islet isolated from 14 deceased multiorgan donors was cultured in Miami modified media-1 supplemented with or without rhPRL (500 μg/L) for 48 hr. β-Cell survival and proliferation (BrdU and Ki-67) were determined by laser scanning cytometry. The cytoprotective effects of rhPRL against noxious stimuli were assessed by flow cytometry (tetramethylrhodamine ethyl ester…

endocrine systemmedicine.medical_specialtyAdenosineCell SurvivalAllopurinolmedicine.medical_treatmentOrgan Preservation SolutionsTransplantation HeterologousCell Culture TechniquesIslets of Langerhans TransplantationApoptosisContext (language use)BiologyArticleMiceRaffinoseInsulin-Secreting CellsInternal medicineCadavermedicineAnimalsHumansInsulinTransplantationgeographygeography.geographical_feature_categorySettore BIO/16 - Anatomia UmanaInsulinIsletGlutathioneRecombinant ProteinsTissue DonorsProlactinCulture MediaProlactinProlactin Pancreatic Islets InflammationTransplantationEndocrinologyCytokineApoptosisCell cultureCytokinesChemokinesCell Divisionhormones hormone substitutes and hormone antagonists
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Conservative Management of Atypical Endometrial Hyperplasia and Early Endometrial Cancer in Childbearing Age Women.

2022

Total hysterectomy and bilateral adnexectomy is the standard treatment for atypical endometrial hyperplasia and early-stage endometrial cancer. However, the recommended surgical treatment precludes future pregnancy when these conditions are diagnosed in women in their fertile age. In these patients, fertility-sparing treatment may be feasible if the desire for childbearing is consistent and specific conditions are present. This review summarizes the available evidence on fertility-sparing management for atypical endometrial hyperplasia and early-stage endometrial cancer. Historically, oral progestins have been the mainstay of conservative management for atypical endometrial hyperplasia and …

fertility-sparing treatmentFertility PreservationGeneral MedicineConservative TreatmentSettore MED/40 - Ginecologia E OstetriciaMetforminEndometrial NeoplasmsProgestinGonadotropin-Releasing HormoneTreatment OutcomeRetrospective StudiePregnancyendometrial cancerEndometrial HyperplasiaHumansEndometrial NeoplasmFemaleendometrial atypical hyperplasiaProgestinsHumanRetrospective StudiesMedicina (Kaunas, Lithuania)
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Finite element analysis of a Bionate ring-shaped customized lumbar disc nucleus prosthesis

2021

[EN] Study design: Biomechanical study of a nucleus replacement with a finite element model. Objective: To validate a Bionate 80A ring-shaped nucleus replacement. Methods: The ANSYS lumbar spine model made from lumbar spine X-rays and magnetic resonance images obtained from cadaveric spine specimens were used. All materials were assumed homogeneous, isotropic, and linearly elastic. We studied three options: intact spine, nucleotomy, and nucleus implant. Two loading conditions were evaluated at L-3-L-4, L-4-L-5, and L-5-S-1 discs: a 1000 N axial compression load and this load after the addition of 8 Nm flexion moment in the sagittal plane plus 8 Nm axial rotation torque. Results: Maximum nuc…

finite element modelLumbar VertebraeINGENIERIA MECANICABiochemistry (medical)Finite Element AnalysisBiomedical EngineeringArtificial LimbsGeneral Chemistrymotion preservationArticleBiomechanical PhenomenaBiomaterialsdisc herniapolycarbonate urethanedegenerative disc diseaseHumansCirurgia Aparells i instrumentsRange of Motion Articularnucleus disc replacement
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Realizacja Konwencji UNESCO z 2003 roku w Polsce z perspektywy folklorysty

2018

The author continues her research on folklore and folklorism in the contemporary culture in the framework of the discussion held currently in Poland on the intangible cultural heritage and all the actions aiming at its protection and preservation. She starts from 2003 UNESCO Convention which coins the new term of intangible cultural heritage to replace the terms folklore and folklorism, commonly used in informal and scientific discourse. The new term covers also material culture. The author has already referred to the complex set of phenomena that accompany the change in terminology, pointing e.g. at the growing discrepancy between the academic theory and the cultural policy of the state. N…

folklorismfolklorepreservation and revitalization of intangible cultural heritageUNESCO ConventionEtnologické rozpravy / Ethnological Disputes
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Application of bacteriocins in vegetable food biopreservation.

2007

Bacteriocins are generally recognized as "natural" compounds able to influence the safety and quality of foods. In the past years, a lot of works have been aimed to the detection, purification and characterisation of bacteriocins, as well as to their use in food preservation strategies. A list of review articles dealing with the application of bacteriocins to the protection of foods of animal origin is also available in literature, but it lacks for a summary on the utilization of bacteriocins in vegetable foods. These biopreservatives can be used in a number of ways in food systems and this paper mainly focuses on the state-of-the-art application of bacteriocins from lactic acid bacteria (L…

food.ingredientFood ContaminationBiologyMicrobiologyfoodBacteriocinBacteriocinsFood Preservationbiopreservazione additivi alimentari alimenti vegetaliVegetablesFood microbiologyHumansFood scienceFood PreservativesBacteriabusiness.industryFood additivedigestive oral and skin physiologyFood preservationfood and beveragesGeneral Medicinebiochemical phenomena metabolism and nutritionBiopreservationBiotechnologyLactobacillusConsumer Product SafetyFermentationFood MicrobiologyFood PreservativesbacteriaFood systemsbusinessFood ScienceFood contaminantInternational journal of food microbiology
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