Search results for "Presse"
showing 10 items of 265 documents
Distinct Signaling Cascades of TREM-1, TLR and NLR in Neutrophils and Monocytic Cells
2013
Triggering receptor expressed on myeloid cells 1 (TREM-1) is an important mediator of innate inflammatory responses in microbial infections and sepsis. TREM-1 ligation on neutrophils (PMN) or monocytes results in the production of proinflammatory cytokines. Engagement of TREM-1 induces the activation of MAP kinases as well as rapid Ca<sup>2+</sup> mobilization. However, a detailed understanding of TREM-1 signaling pathways is currently lacking. We evaluated the TREM-1 signaling hierarchy in monocytic cells and found that the acute myeloid leukemia cell line MUTZ-3 expresses TREM-1 in a natural and functional manner. We compared essential signaling molecules of the TREM-1, TLR an…
Optimal calculation of the pair correlation function for an orthorhombic system
2012
We present a new computational method to calculate arbitrary pair correlation functions of an orthorombic system in the most efficient way. The algorithm is demonstrated by the calculation of the radial distribution function of shock compressed liquid hydrogen.
Social and emotional functions in three patients with medial frontal lobe damage including the anterior cingulate cortex
2006
INTRODUCTION: The aim of this study was to explore social and emotional functions in patients with medial frontal damage including the anterior cingulate cortex (ACC). METHODS: Three patients with medial frontal lobe lesions primarily involving the ACC performed tasks on motivational decision making, emotional facial expression recognition, and social cognition, including theory of mind (ToM). Their performance on these tasks was compared with age and education matched healthy controls. RESULTS: Patient performance on the motivational decision making and social situations tasks did not differ from controls. Selective emotional facial expression recognition impairment for fear was evident in…
Presse et événement
2011
International audience
Identifying conserved genes involved in crop tolerance to cold stress
2022
Low temperature is a limiting factor for crop productivity in tropical and subtropical climates. Cold stress response in plants involves perceiving and relaying the signal through a transcriptional cascade composed of different transduction components, resulting in altered gene activity. We performed a meta-analysis of four previously published datasets of cold-tolerant and cold-sensitive crops to better understand the gene regulatory networks and identify key genes involved in cold stress tolerance conserved across phylogenetically distant species. Re-analysing the raw data with the same bioinformatics pipeline, we identified common cold tolerance-related genes. We found 236 and 242 common…
On the construction of classes of suffix trees for square matrices: Algorithms and applications
1995
Given an n × n TEXT matrix with entries defined over an ordered alphabet σ, we introduce 4n−1 classes of index data structures for TEXT. Those indices are informally the two-dimensional analog of the suffix tree of a string [15], allowing on-line searches and statistics to be performed on TEXT. We provide one simple algorithm that efficiently builds any chosen index in those classes in O(n2 log n) worst case time using O(n2) space. The algorithm can be modified to require optimal O(n2) expected time for bounded σ.
On-line construction of two-dimensional suffix trees
1997
We present a new technique, which we refer to as implicit updates, based on which we obtain: (a) an algorithm for the on-line construction of the Lsuffix tree of an n x n matrix A — this data structure, described in [13], is the two-dimensional analog of the suffix tree of a string; (b) simple algorithms implementing primitive operations for LZ1-type on-dine lossless image compression methods. Those methods, recently introduced by Storer [35], are generalizations of LZl-type compression methods for strings (see also [24, 31]). For the problem in (a), we get nearly an order of magnitude improvement over algorithms that can be derived from known techniques [13]. For the problem in (b), we do …
Linear-size suffix tries
2016
Suffix trees are highly regarded data structures for text indexing and string algorithms [MCreight 76, Weiner 73]. For any given string w of length n = | w | , a suffix tree for w takes O ( n ) nodes and links. It is often presented as a compacted version of a suffix trie for w, where the latter is the trie (or digital search tree) built on the suffixes of w. Here the compaction process replaces each maximal chain of unary nodes with a single arc. For this, the suffix tree requires that the labels of its arcs are substrings encoded as pointers to w (or equivalent information). On the contrary, the arcs of the suffix trie are labeled by single symbols but there can be Θ ( n 2 ) nodes and lin…
JANE: efficient mapping of prokaryotic ESTs and variable length sequence reads on related template genomes
2009
Abstract Background ESTs or variable sequence reads can be available in prokaryotic studies well before a complete genome is known. Use cases include (i) transcriptome studies or (ii) single cell sequencing of bacteria. Without suitable software their further analysis and mapping would have to await finalization of the corresponding genome. Results The tool JANE rapidly maps ESTs or variable sequence reads in prokaryotic sequencing and transcriptome efforts to related template genomes. It provides an easy-to-use graphics interface for information retrieval and a toolkit for EST or nucleotide sequence function prediction. Furthermore, we developed for rapid mapping an enhanced sequence align…
Improved Statistically Based Retrievals via Spatial-Spectral Data Compression for IASI Data
2019
In this paper, we analyze the effect of spatial and spectral compression on the performance of statistically based retrieval. Although the quality of the information is not com- pletely preserved during the coding process, experiments reveal that a certain amount of compression may yield a positive impact on the accuracy of retrievals. We unveil two strategies, both with interesting benefits: either to apply a very high compression, which still maintains the same retrieval performance as that obtained for uncompressed data; or to apply a moderate to high compression, which improves the performance. As a second contribution of this paper, we focus on the origins of these benefits. On the one…