Search results for "Primate"

showing 7 items of 147 documents

Pinpointing the PRDM9-PRDM7 Gene Duplication Event During Primate Divergence

2021

Studies on the function of PRDM9 in model systems and its evolution during vertebrate divergence shed light on the basic molecular mechanisms of hybrid sterility and its evolutionary consequences. However, information regarding PRDM9-homolog, PRDM7, whose origin is placed in the primate evolutionary tree, as well as information about the fast-evolving DNA-binding zinc finger array of strepsirrhine PRDM9 are scarce. Thus, we aimed to narrow down the date of the duplication event leading to the emergence of PRDM7 during primate evolution by comparing the phylogenetic tree reconstructions of representative primate samples of PRDM orthologs and paralogs. To confirm our PRDM7 paralogization patt…

lcsh:Geneticslcsh:QH426-470Geneticsgene duplicationparalogizationMolecular MedicinePRDM7Brief Research ReportGenetics (clinical)PRDM9primate evolution570 Biowissenschaften570 Life sciencesFrontiers in Genetics
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Modulation of the Endocannabinoids N-Arachidonoylethanolamine (AEA) and 2-Arachidonoylglycerol (2-AG) on Executive Functions in Human.

2013

Animal studies point to an implication of the endocannabinoid system on executive functions. In humans, several studies have suggested an association between acute or chronic use of exogenous cannabinoids (Δ9-tetrahydrocannabinol) and executive impairments. However, to date, no published reports establish the relationship between endocannabinoids, as biomarkers of the cannabinoid neurotransmission system, and executive functioning in humans. The aim of the present study was to explore the association between circulating levels of plasma endocannabinoids N-arachidonoylethanolamine (AEA) and 2-Arachidonoylglycerol (2-AG) and executive functions (decision making, response inhibition and cognit…

lcsh:MedicineNeuropsychological TestsSocial and Behavioral SciencesPrefrontal cortexReceptores de cannabinoides:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]Executive FunctionEndocrinologyCognitionWisconsin Card Sorting TestEndocrinologiaHuman PerformanceMedicinePsychologyendocannabinoid systemPrefrontal cortexlcsh:ScienceProblem SolvingPsychiatryMultidisciplinaryCognitive NeurologyCognitive flexibilityPresa de decisionsCognitionMiddle AgedExecutive functionsexecutive functionsHumanos2-arachidonoylglycerolSubstance abuseEndocannabinoidesMental HealthNeurologyCognicióMedicineFemalelipids (amino acids peptides and proteins):Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Membrane Proteins::Receptors Cell Surface::Receptors G-Protein-Coupled::Receptors Cannabinoid [Medical Subject Headings]Animal behaviorClinical psychology:Chemicals and Drugs::Lipids::Fatty Acids::Fatty Acids Unsaturated::Arachidonic Acids [Medical Subject Headings]HumanResearch ArticleAdultN-arachidonoylethanolamine:Psychiatry and Psychology::Mental Disorders::Substance-Related Disorders::Marijuana Abuse [Medical Subject Headings]Polyunsaturated AlkamidesCognitive NeuroscienceDecision MakingArachidonic AcidsGlyceridesYoung AdultCannabinoides -- ReceptorsNeuropsychologyCànnabis:Diseases::Nervous System Diseases::Neurodegenerative Diseases [Medical Subject Headings]Pruebas neuropsicológicasÁcidos araquidónicosHumansFunción ejecutivaBiologyCannabisCannabinoides -- Efectes fisiològics:Anatomy::Nervous System::Central Nervous System [Medical Subject Headings]Behavior:Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Neurotransmitter Agents::Endocannabinoids [Medical Subject Headings]business.industrylcsh:RCognitive Psychologymedicine.diseaseIowa gambling taskEnfermedades neurodegenerativasAbuso de marihuanaSistema nervioso central:Psychiatry and Psychology::Behavioral Disciplines and Activities::Psychological Tests::Neuropsychological Tests [Medical Subject Headings]:Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Executive Function [Medical Subject Headings]lcsh:QbusinessDecision makingStroop effectNeuroscienceEndocannabinoids
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Recomendaciones preventivas cardiovasculares. Actualización PAPPS 2020

2020

The recommendations of the semFYC's Program for Preventive Activities and Health Promotion (PAPPS) for the prevention of cardiovascular diseases (CVD) are presented. The following sections are included: Epidemiological review, where the current morbidity and mortality of CVD in Spain and its evolution as well as the main risk factors are described; Cardiovascular (CV) risk tables and recommendations for the calculation of CV risk; Main risk factors such as arterial hypertension, dyslipidemia and diabetes mellitus, describing the method for their diagnosis, therapeutic objectives and recommendations for lifestyle measures and pharmacological treatment; Indications for antiplatelet therapy, a…

medicine.medical_specialtyFamily medicineMedicina:Health Care::Environment and Public Health::Public Health::Epidemiologic Factors::Causality::Risk Factors [Medical Subject Headings]030204 cardiovascular system & hematologyPharmacological treatment:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]:Diseases::Cardiovascular Diseases::Vascular Diseases::Hypertension [Medical Subject Headings]03 medical and health sciences0302 clinical medicineDiabetes mellitusDiabetes mellitusEpidemiologymedicine030212 general & internal medicineIntensive care medicine:Diseases::Cardiovascular Diseases [Medical Subject Headings]lcsh:R5-920:Diseases::Endocrine System Diseases::Diabetes Mellitus [Medical Subject Headings]business.industryMedicina de familia:Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology Social::Life Style [Medical Subject Headings]Atrial fibrillationGeneral MedicineAtención primariamedicine.diseasePrimary careCardiovasculardiseasesHealth promotionCardiovascular diseases:Health Care::Health Care Facilities Manpower and Services::Health Promotion [Medical Subject Headings]Preventive activitiesEnfermedades cardiovasculareslcsh:Medicine (General)Family PracticebusinessDyslipidemia
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Multidirectional chromosome painting reveals a remarkable syntenic homology between the greater galagos and the slow loris.

2006

We report on the first reciprocal chromosome painting of lorisoids and humans. The chromosome painting showed a remarkable syntenic homology between Otolemur and Nycticebus. Eight derived syntenic associations of human segments are common to both Otolemur and Nycticebus, indicative of a considerable period of common evolution between the greater galago and the slow loris. Five additional Robertsonian translocations form the slow loris karyotype, while the remaining chromosomes are syntenically equivalent, although some differ in terms of centromere position and heterochromatin additions. Strikingly, the breakpoints of the human chromosomes found fragmented in these two species are apparentl…

medicine.medical_specialtyGreater galagoChromosomal translocationgenome evolutionphylogenyprimateSyntenycytogeneticsCell LineChromosome PaintingEvolution MolecularCentromeremedicineAnimalsChromosomes HumanHumansEcology Evolution Behavior and SystematicsSyntenyGeneticsbiologySlow lorisCytogeneticsChromosomeKaryotypeFibroblastsbiology.organism_classificationLorisidaestrepsirrhinelorisoidKaryotypingAnimal Science and ZoologyAmerican journal of primatology
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Factores de predicción de dosificación inadecuada de rivaroxabán utilizando la ecuación de CKD-EPI

2021

Yes

medicine.medical_specialtyPatientsCKD-EPI:Diseases::Hemic and Lymphatic Diseases::Hematologic Diseases::Blood Coagulation Disorders [Medical Subject Headings]Dosislcsh:RC870-923:Anatomy::Cardiovascular System::Blood Vessels::Arteries::Aorta [Medical Subject Headings]:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]DosageRivaroxabanRivaroxabánmedicineRenal insufficiency chronicInsuficiencia renal crónicaGynecology:Diseases::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases::Renal Insufficiency::Renal Insufficiency Chronic [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Clinical Trials as Topic::Observational Study as Topic [Medical Subject Headings]business.industry:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Dosage Calculations [Medical Subject Headings]lcsh:Diseases of the genitourinary system. Urology:Persons::Persons::Patients [Medical Subject Headings]NephrologyPacientesDosificaciónbusiness:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Prescriptions [Medical Subject Headings]Nefrología
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Load progression criteria in exercise programmes in lower limb tendinopathy: a systematic review

2020

ObjectiveThe objective of this study is to summarise and analyse the current literature about what progression criteria are applied in loading exercise programmes in lower limb tendinopathies and their evidence and effectiveness.DesignSystematic review.MethodsPubMed, Embase, Scopus and PEDrowere searched from inception to 24 September 2020. The inclusion criteria were randomised controlled trials that included patients with midportion Achilles, patellar or gluteal tendinopathy; assessed function, pain or performance; included at least one group where progressive physical exercise was administered as monotherapy; included at least a control group. We excluded studies that included subjects w…

medicine.medical_specialtySports medicineSubjective perceptionPainPhysical exerciseAchilles TendonLower limbLower limb:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]:Anthropology Education Sociology and Social Phenomena::Human Activities::Exercise [Medical Subject Headings]medicineHumans:Anatomy::Body Regions::Extremities::Lower Extremity [Medical Subject Headings]:Anatomy::Musculoskeletal System::Tendons::Achilles Tendon [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Rehabilitation::Exercise Therapy [Medical Subject Headings]1506Methodological quality1727ExerciseExtremidad inferiorsports medicinebusiness.industryRevisión sistemáticaRrehabilitation medicineGeneral Medicine:Diseases::Pathological Conditions Signs and Symptoms::Signs and Symptoms::Pain [Medical Subject Headings]medicine.diseaseEjercicio físicoExercise TherapyExercise programmeTendinopatíaLower Extremitypain managementTendinopathyPhysical therapySystematic review:Diseases::Musculoskeletal Diseases::Muscular Diseases::Tendinopathy [Medical Subject Headings]MedicineTendinopathymusculoskeletal disordersDolorbusinessGluteal tendinopathy
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Prymat Papieża

2015

Problematyka teologicznego uzasadnienia urzędu papieskiego obejmuje tradycyjnie trzy pytania: Czy Jezus w osobie Piotra założył urząd uniwersalnej jedności Kościoła (petrinitas)? Czy istnieje sukcesja tego urzędu począwszy od Piotra po dzień dzisiejszy (perpetuitas)? Wjaki sposób urząd Piotra wiąże się z Rzymem jako miejscem jego sprawowania (romanitas)? W artykule przedstawiono nowe koncepcje teologiczne dotyczące prymatu papieża, biorąc pod uwagę obraz Piotra w Nowym Testamencie oraz proces rozwoju urzędu papieskiego w postaci prymatu biskupa Rzymu. Wostatniej części przedłożenia nakreślono perspektywę ekumeniczną, rozpatrywaną na tle teologicznych i magisterialnych wypowiedzi na temat ro…

perspektywa ekumeniczna odnos´nie do prymatuszkoły teologiczne„posługa Piotra”Papal OfficeEcclesiological Schoolsrozwój dogmatówPrimate of the Bishop of RomeDevelopment of Dogmasurzad˛ papieskiPapal Office in Ecumenical Perspectiveprymat biskupa RzymuPeter’s MinistryRoczniki Teologiczne
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