Search results for "Principal Component Analysi"

showing 10 items of 489 documents

Kinematic Sub-Populations in Bull Spermatozoa: A Comparison of Classical and Bayesian Approaches

2020

The ejaculate is heterogenous and sperm sub-populations with different kinematic patterns can be identified in various species. Nevertheless, although these sub-populations are statistically well defined, the statistical differences are not always relevant. The aim of the present study was to characterize kinematic sub-populations in sperm from two bovine species, and diluted with different commercial extenders, and to determine the statistical relevance of sub-populations through Bayesian analysis. Semen from 10 bulls was evaluated after thawing. An ISAS&reg

0301 basic medicineendocrine systemMultivariate statisticsKinematicsCASABayesian probabilitySemenKinematicsBiologyArticleGeneral Biochemistry Genetics and Molecular Biologylaw.invention03 medical and health sciences0302 clinical medicinelawStatisticsbulllcsh:QH301-705.5030219 obstetrics & reproductive medicineGeneral Immunology and MicrobiologySub populationsurogenital systemExtenderMotilitySpermSpermatozoaBulls030104 developmental biologylcsh:Biology (General)ClusterPrincipal component analysisGeneral Agricultural and Biological Sciences
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Monitoring of system conditioning after blank injections in untargeted UPLC-MS metabolomic analysis

2019

AbstractUltra-performance liquid chromatography – mass spectrometry (UPLC-MS) is widely used for untargeted metabolomics in biomedical research. To optimize the quality and precision of UPLC-MS metabolomic analysis, evaluation of blank samples for the elimination of background features is required. Although blanks are usually run either at the beginning or at the end of a sequence of samples, a systematic analysis of their effect of the instrument performance has not been properly documented. Using the analysis of two common bio-fluids (plasma and urine), we describe how the injection of blank samples within a sequence of samples may affect both the chromatographic and MS detection performa…

0301 basic medicinelcsh:MedicineUrineMass spectrometryBlankMass SpectrometryArticlePlasma03 medical and health sciences0302 clinical medicineMetabolomicsHumansMetabolomicslcsh:ScienceChromatography High Pressure LiquidPrincipal Component AnalysisMultidisciplinaryChromatographyChemistrylcsh:RData acquisition030104 developmental biologyUntargeted metabolomicsDetection performanceConditioninglcsh:QUplc ms ms030217 neurology & neurosurgeryScientific Reports
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Penalized classification for optimal statistical selection of markers from high-throughput genotyping: application in sheep breeds

2018

The identification of individuals’ breed of origin has several practical applications in livestock and is useful in different biological contexts such as conservation genetics, breeding and authentication of animal products. In this paper, penalized multinomial regression was applied to identify the minimum number of single nucleotide polymorphisms (SNPs) from high-throughput genotyping data for individual assignment to dairy sheep breeds reared in Sicily. The combined use of penalized multinomial regression and stability selection reduced the number of SNPs required to 48. A final validation step on an independent population was carried out obtaining 100% correctly classified individuals. …

0301 basic medicinepenalized multinomial regression stability selection sheep breeds livestock genetic resources single nucleotide polymorphism markersGenotypePopulationSingle-nucleotide polymorphismComputational biologyBreedingBiologySF1-1100Polymorphism Single Nucleotidesheep breeds03 medical and health sciencesSettore AGR/17 - Zootecnica Generale E Miglioramento Geneticolivestock genetic resourcessingle nucleotide polymorphism markersAnimalseducationGenotypingSelection (genetic algorithm)Multinomial logistic regressionGeneticsPrincipal Component Analysiseducation.field_of_studySheeppenalized multinomial regressionHigh-Throughput Nucleotide SequencingBreedstability selectionAnimal cultureRandom forest030104 developmental biologyPrincipal component analysisAnimal Science and ZoologySettore SECS-S/01 - StatisticaBiomarkers
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Canonical Variate Analysis of Sensory Profiling Data

2015

Principal Component Analysis (PCA) of product mean scores is generally used to obtain a product map from sensory profiling data. However, this approach does not take into account the variance of the product mean scores due to the individual panelist variability. Therefore, Canonical Variate Analysis (CVA) of the product effect in the two-way multivariate analysis of variance (MANOVA) should be considered as a natural alternative analysis to PCA. Indeed, it is the extension of the classical univariate approach used for the analysis of each descriptor separately. This analysis generates successive components maximizing product discrimination as measured by the usual Fisher statistics in analy…

0303 health sciences030309 nutrition & dieteticsComputer scienceUnivariateSensory system04 agricultural and veterinary sciences040401 food scienceSensory analysisSensory Systems03 medical and health sciences0404 agricultural biotechnologyCanonical variate analysisMultivariate analysis of varianceStatisticsPrincipal component analysisProfiling (information science)Analysis of varianceFood ScienceJournal of Sensory Studies
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Comparison of conventional descriptive analysis and a citation frequency-based descriptive method for odor profiling: An application to Burgundy Pino…

2010

International audience; The limitations of intensity scoring when describing the odor characteristics of a complex product have been documented in the literature. In the present work, the odor properties of 12 Burgundy Pinot noir wines were described by two independent panels performing, respectively, an intensity-based (conventional descriptive analysis) and a citation frequency-based method. Methods were compared according to three criteria: similarity of the sensory maps, control of panel performance and practical aspects. Intensity scoring and citation frequency data were analyzed, respectively, by Principal Components Analysis (PCA) and Correspondence Analysis (CA) followed by Hierarch…

030309 nutrition & dietetics[ SDV.AEN ] Life Sciences [q-bio]/Food and NutritionSensory analysisCorrespondence analysis03 medical and health sciences0404 agricultural biotechnologySENSORY ANALYSISStatistics[SDV.IDA]Life Sciences [q-bio]/Food engineeringCluster analysisComputingMilieux_MISCELLANEOUSMathematicsWinePINOT NOIR0303 health sciencesFREQUENCY OF CITATIONNutrition and DieteticsDescriptive statisticsbusiness.industryDESCRIPTIVE PROFILEWINE04 agricultural and veterinary sciencesCONVENTIONAL DA040401 food scienceHierarchical clusteringOdorPrincipal component analysisArtificial intelligencebusiness[SDV.AEN]Life Sciences [q-bio]/Food and NutritionMETHOD COMPARISONFood Science
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Orientation-invariance of individual differences in three face processing tasks

2019

Numerous studies have reported impairments in perception and recognition, and, particularly, in part-integration of faces following picture-plane inversion. Whether these findings support the notion that inversion changes face processing qualitatively remains a topic of debate. To examine whether associations and dissociations of the human face processing ability depend on stimulus orientation, we measured face recognition with the Cambridge Face Memory Test (CFMT), along with experimental tests of face perception and selective attention to faces and non-face objects in a sample of 314 participants. Results showed strong inversion effects for all face-related tasks, and modest ones for non-…

100142media_common.quotation_subjectselective attentionface inversion effectStimulus (physiology)Facial recognition system050105 experimental psychology03 medical and health sciences0302 clinical medicineface-specific processingFace perceptionPerceptionPsychology and Cognitive Neuroscience0501 psychology and cognitive sciencesSelective attentionMemory testlcsh:Scienceindividual differencesFactor analysismedia_commonMultidisciplinary05 social sciences205Principal component analysislcsh:QPsychology030217 neurology & neurosurgeryCognitive psychologyResearch ArticleRoyal Society Open Science
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Statistical analysis of sensory profiling data. Graphs for presenting results (PCA and ANOVA)

2000

Abstract A principal component analysis is performed to analyse the matrix of median values, with 16 varieties in rows, and all descriptors in columns. Only texture descriptors contribute to the definition of the main axes. Six varieties are identified that score high on mealiness and low on moisture, the 10 other varieties are ordered according to a mashable axis which involves texture descriptors. Next we exclude texture descriptors since the main characteristics are already found, and mealy varieties since they are not suitable for steamed potatoes. A mixed linear model (ANOVA) with random subject effects is then used for each descriptor. Flavour and taste differences are found among the…

2. Zero hunger0303 health sciencesNutrition and Dietetics030309 nutrition & dieteticsFlavour04 agricultural and veterinary sciences[SDV.IDA] Life Sciences [q-bio]/Food engineering040401 food scienceSensory analysis03 medical and health sciences0404 agricultural biotechnology[SDV.IDA]Life Sciences [q-bio]/Food engineeringPrincipal component analysisMixed linear modelStatisticsStatistical analysisAnalysis of varianceComputingMilieux_MISCELLANEOUSFood ScienceMathematicsFood Quality and Preference
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Metabolic signatures across the full spectrum of non-alcoholic fatty liver disease.

2022

Funder: European Commission

ALTtype 2 diabetes mellitusROC receiving operator characteristicaspartate aminotransferaseHSDLDL low-density lipoproteinUHPLC ultrahigh-performance liquid chromatographyROCHCCNon-alcoholic steatohepatitisGCPCANASHGastroenterology2-HB 2-hydroxybutanoic acid; 3-HB 3-hydroxybutanoic acid; ALT alanine aminotransferase; AST aspartate aminotransferase; CE cholesterol ester; Cer ceramide; FFA free fatty acid; FLIP Fatty Liver Inhibition of Progression; Fibrosis; GC gas chromatography; HCC hepatocellular carcinoma; HSD honest significant difference; LC lipid cluster; LDL low-density lipoprotein; LM lipid and metabolite; LMC lipid metabolite and clinical variable; LPC lysophosphatidylcholine; Lipidomics; Mass spectrometry; Metabolomics; NAFL non-alcoholic fatty liver; NAFLD non-alcoholic fatty liver disease; NAS NASH activity score; NASH non-alcoholic steatohepatitis; NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network; NRR non-rejection rate; Non-alcoholic steatohepatitis; PC(O) ether PC; PC phosphatidylcholine; PCA principal component analysis; PE phosphatidylethanolamine; QTOFMS quadrupole-time-of-flight mass spectrometry; ROC receiving operator characteristic; SAF steatosis activity and fibrosis; SM sphingomyelin; T2DM type 2 diabetes mellitus; TG triacylglycerol; UHPLC ultrahigh-performance liquid chromatographySAFSAF steatosis activity and fibrosisLM lipid and metabolitehonest significant differenceHSD honest significant differenceTG triacylglycerolnon-rejection ratecholesterol esterPCPEGC gas chromatographyfree fatty acidFLIPNASH non-alcoholic steatohepatitisNIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkBIOMARKERST2DMPE phosphatidylethanolamineLDLlipidNAFLDFFA free fatty acid2-HBMetabolomicsNAFL non-alcoholic fatty liverLMCphosphatidylcholineScience & TechnologySM sphingomyelinGastroenterology & HepatologyMass spectrometryactivitynutritional and metabolic diseasesT2DM type 2 diabetes mellitusACIDSreceiving operator characteristicdigestive system diseasesquadrupole-time-of-flight mass spectrometryLC lipid clusterlow-density lipoproteinNAS2-HB 2-hydroxybutanoic acidNAS NASH activity scoreQTOFMSether PCNRRSCORING SYSTEMprincipal component analysisgas chromatographyLC2-hydroxybutanoic acidPROGRESSIONAST aspartate aminotransferaseLMPC phosphatidylcholinePC(O)MARKERSUHPLCsteatosisTOOLImmunology and AllergyINSULIN-RESISTANCECerSMFatty Liver Inhibition of Progressionhepatocellular carcinoma2-HB 2-hydroxybutanoic acid NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network NRR non-rejection rate Non-alcoholic steatohepatitis PC(O) ether PC PC phosphatidylcholine PCA principal component analysis PE phosphatidylethanolamine QTOFMS quadrupole-time-of-flight mass spectrometry ROC receiving operator characteristic SAF steatosis activity and fibrosis SM T2DM type 2 diabetes mellitus TG triacylglycerol UHPLC ultrahigh-performance liquid chromatographyultrahigh-performance liquid chromatographyCELPC3-HBNAFLnon-alcoholic fatty liverTGtriacylglycerolNRR non-rejection rateLife Sciences & BiomedicineNAFLD non-alcoholic fatty liver diseaseFLIP Fatty Liver Inhibition of Progressionalanine aminotransferasemetaboliteCer ceramideCE cholesterol estersphingomyelinlysophosphatidylcholineand fibrosisALT alanine aminotransferaseInternal MedicineceramideNational Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkAST3-HB 3-hydroxybutanoic acidQTOFMS quadrupole-time-of-flight mass spectrometryPCA principal component analysisLPC lysophosphatidylcholineHepatologynon-alcoholic fatty liver diseaseand clinical variablePC(O) ether PC3-hydroxybutanoic acidFibrosisNASH activity scoreNIDDK NASH-CRNlipid clusterlipid and metabolitephosphatidylethanolamineLipidomicsLMC lipid metabolite and clinical variableFFAHCC hepatocellular carcinomaJHEP reports : innovation in hepatology
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A comparison among different techniques for human ERG signals processing and classification

2014

A comparison among different techniques for human ERG signals processing and classification ( Articles not published yet, but available online Article in press About articles in press (opens in a new window) ) Barraco, R.a, Persano Adorno, D.a , Brai, M.a, Tranchina, L.b a Dipartimento di Fisica e Chimica, Università di Palermo and CNISM, Viale delle Scienze, Ed. 18, I-90128 Palermo, Italy b Laboratorio di Fisica e Tecnologie Relative - UniNetLab, Università di Palermo, Viale delle Scienze, Ed. 18, I-90128 Palermo, Italy Abstract Feature detection in biomedical signals is crucial for deepening our knowledge about the involved physiological processes. To achieve this aim, many analytic appro…

Achromatopsiagenetic structuresComputer scienceBiophysicsGeneral Physics and AstronomyColor Vision DefectsPrincipal component analysiWavelet analysisPattern Recognition AutomatedWaveletRetinal pathologieElectroretinographymedicineHumansRadiology Nuclear Medicine and imagingComputer visionFeature detection (computer vision)Principal Component AnalysisSignal processingFourier Analysisbusiness.industryWavelet transformSignal Processing Computer-AssistedPattern recognitionGeneral Medicinemedicine.diseaseSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)eye diseasesERG signalClinical diagnosisPrincipal component analysissense organsArtificial intelligencebusinessErgPhysica Medica
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Endometrial gene expression analysis at the time of embryo implantation in women with unexplained infertility

2009

Successful embryo implantation depends on the quality of the embryo, as well as on the receptivity of the endometrium. The aim of this study was to investigate the endometrial gene expression profile in women with unexplained infertility in comparison with fertile controls at the time of embryo implantation in order to find potential predictive markers of uterine receptivity and to identify the molecular mechanisms of infertility. High-density oligonucleotide gene arrays, comprising 44 000 gene targets, were used to define the endometrial gene expression profile in infertile (n = 4) and fertile (n = 5) women during the mid-secretory phase (day LH + 7). Microarray results were validated usin…

AdultInfertilityEmbryologymedicine.medical_specialtyMicroarrayBiologyEndometriumAndrologyEndometriumPregnancyInternal medicineGeneticsmedicineHumansEmbryo ImplantationMolecular BiologyCellular localizationOligonucleotide Array Sequence AnalysisUnexplained infertilityRegulation of gene expressionPrincipal Component AnalysisReverse Transcriptase Polymerase Chain ReactionGene Expression ProfilingObstetrics and GynecologyCell Biologymedicine.diseaseGene expression profilingmedicine.anatomical_structureEndocrinologyGene Expression RegulationReproductive MedicineIn uteroFemaleInfertility FemaleDevelopmental BiologyMolecular Human Reproduction
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