Search results for "Probability."
showing 10 items of 3396 documents
Optimal selection of individuals for repeated covariate measurements in follow-up studies
2016
Repeated covariate measurements bring important information on the time-varying risk factors in long epidemiological follow-up studies. However, due to budget limitations, it may be possible to carry out the repeated measurements only for a subset of the cohort. We study cost-efficient alternatives for the simple random sampling in the selection of the individuals to be remeasured. The proposed selection criteria are based on forms of the D-optimality. The selection methods are compared with the simulation studies and illustrated with the data from the East–West study carried out in Finland from 1959 to 1999. The results indicate that cost savings can be achieved if the selection is focuse…
Effects of anemia correction with epoetin beta in patients receiving radiochemotherapy for advanced cervical cancer
2007
Patients with cervical cancer frequently suffer from anemia. This two-stage, adaptive-design study investigated the effect of anemia correction with epoetin beta on treatment outcomes. Patients with stage IIB–IVA cervical cancer received radiochemotherapy (RCT) and were randomized to epoetin 150 IU/kg three times weekly (n = 34) or standard care (control; n = 40) for up to 12 weeks. Primary end point for stage 1 aimed to establish a correlation between anemia correction and treatment failure (no complete response or relapsing within 6 months after RCT initiation) as a proof of concept before moving into stage 2. Secondary end points included progression/relapse-free survival, overall surviv…
Effect of Isometric Upper-Extremity Exercises on the Activation of Core Stabilizing Muscles
2007
Abstract Tarnanen SP, Ylinen JJ, Siekkinen KM, Malkia EA, Kautiainen HJ, Hakkinen AH. Effect of isometric upper-extremity exercises on the activation of core stabilizing muscles. Objective To evaluate whether isometric exercises for the upper extremities could sufficiently activate core stabilizing muscles to increase muscle strength. Design Cross-sectional study. Setting Department of physical medicine and rehabilitation at a Finnish hospital. Participants Healthy adult women (N=20). Interventions Not applicable. Main Outcome Measures Peak isometric strength of the back and abdominal muscles was measured and relative loading in 5 test exercises was evaluated by surface electromyography. Re…
How to demonstrate that eSET does not compromise the likelihood of having a baby?
2009
BACKGROUND: In several randomized studies, elective single embryo transfer (eSET) has proven its effectiveness in reducing twin pregnancy rates while obtaining acceptable overall pregnancy rates. However, there is no outcome measurement consensus to evaluate the effectiveness of eSET versus double-embryo transfer (DET). METHODS: This study evaluated whether or not adopting an eSET strategy instead of a DET strategy lowers the probability of having at least one live-born infant in good prognosis couples. Seven hundred and twenty-six couples were divided into two groups. The retrospective arm of the study was undertaken on the first group of couples (n = 483, DET group) and the prospective ar…
The effect of agglomeration economies and geography on the survival of accommodation businesses in Sicily
2021
The study explores the geographical pattern of the accommodation industry in the Italian insular region of Sicily, focusing on the determinants of the risk of market exit. We adopt a standard framework of business survival analysis where agglomeration economies play an important role. We then extend the analysis by considering the role of geography to explore whether the risk of market exit depends on nearness to desirable amenities. The geography is here measured by the distance from the coast and the altitude of the place where the firm is located. When we look at the entire population of accommodation firms that started between 2010 and 2014, we find evidence that the risk of failure inc…
Development and validation of prediction model to estimate 10-year risk of all-cause mortality using modern statistical learning methods: a large pop…
2021
Abstract Background In increasingly ageing populations, there is an emergent need to develop a robust prediction model for estimating an individual absolute risk for all-cause mortality, so that relevant assessments and interventions can be targeted appropriately. The objective of the study was to derive, evaluate and validate (internally and externally) a risk prediction model allowing rapid estimations of an absolute risk of all-cause mortality in the following 10 years. Methods For the model development, data came from English Longitudinal Study of Ageing study, which comprised 9154 population-representative individuals aged 50–75 years, 1240 (13.5%) of whom died during the 10-year follo…
Pandemic Prevention and Personality Psychology: Gender Differences in Preventive Health Behaviors during COVID-19 and the Roles of Agreeableness and …
2022
One of the greatest public health crises in recent times, the COVID-19 pandemic, has come with a myriad of challenges in terms of health communication and public cooperation to prevent the spread of the disease. Understanding which are the key determinants that make certain individuals more cooperative is key in effectively tackling pandemics and similar future challenges. In the present study (N = 800), we investigated whether gender differences in compliance with preventive health behaviors (PHB) at the onset of the COVID-19 pandemic could be established, and, if so, whether the personality traits of agreeableness and conscientiousness could help explain this presumed relationship. Consis…
Products of snowflaked Euclidean lines are not minimal for looking down
2017
We show that products of snowflaked Euclidean lines are not minimal for looking down. This question was raised in Fractured fractals and broken dreams, Problem 11.17, by David and Semmes. The proof uses arguments developed by Le Donne, Li and Rajala to prove that the Heisenberg group is not minimal for looking down. By a method of shortcuts, we define a new distance $d$ such that the product of snowflaked Euclidean lines looks down on $(\mathbb R^N,d)$, but not vice versa.
Search for neutral MSSM Higgs bosons at LEP
2006
The four LEP collaborations, ALEPH, DELPHI, L3 and OPAL, have searched for the neutral Higgs bosons which are predicted by the Minimal Supersymmetric Standard Model (MSSM). The data of the four collaborations are statistically combined and examined for their consistency with the background hypothesis and with a possible Higgs boson signal. The combined LEP data show no significant excess of events which would indicate the production of Higgs bosons. The search results are used to set upper bounds on the cross-sections of various Higgs-like event topologies. The results are interpreted within the MSSM in a number of "benchmark" models, including CP-conserving and CP-violating scenarios. Thes…
Rejoinder on: Natural Induction: An Objective Bayesian Approach
2009
Giron and Moreno. We certainly agree with Professors Giron and Moreno on the interest in sensitivity of any Bayesian result to changes in the prior. That said, we also consider of considerable pragmatic importance to be able to single out a unique, particular prior which may reasonably be proposed as the reference prior for the problem under study, in the sense that the corresponding posterior of the quantity of interest could be routinely used in practice when no useful prior information is available or acceptable. This is precisely what we have tried to do for the twin problems of the rule of succession and the law of natural induction. The discussants consider the limiting binomial versi…