Search results for "Probability"
showing 10 items of 3417 documents
Central nervous system involvement at first relapse in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycl…
2009
Background The prevalence of and risk factors for central nervous system recurrence in patients with acute promyelocytic leukemia are not well established and remain a controversial matter. Design and Methods Between 1996 and 2005, 739 patients with newly diagnosed acute promyelocytic leukemia enrolled in two consecutive trials (PETHEMA LPA96 and LPA99) received induction therapy-with all-trans retinoic acid and idarubicin. Consolidation therapy comprised three courses of anthracycline monochemotherapy (LPA96), with all-trans retinoic acid and reinforced doses of idarubicin in patients with an intermediate or high risk of relapse (LPA99). Central nervous system prophylaxis was not given. Re…
Patients' and physicians' preferences for type 2 diabetes mellitus treatments in Spain and Portugal: a discrete choice experiment.
2015
Objective: To assess Spanish and Portuguese patients' and physicians' preferences regarding type 2 diabetes mellitus (T2DM) treatments and the monthly willingness to pay (WTP) to gain benefits or avoid side effects. Methods: An observational, multicenter, exploratory study focused on routine clinical practice in Spain and Portugal. Physicians were recruited from multiple hospitals and outpatient clinics, while patients were recruited from eleven centers operating in the public health care system in different autonomous communities in Spain and Portugal. Preferences were measured via a discrete choice experiment by rating multiple T2DM medication attributes. Data were analyzed using the cond…
Particle identification in ALICE: a Bayesian approach
2016
We present a Bayesian approach to particle identification (PID) within the ALICE experiment. The aim is to more effectively combine the particle identification capabilities of its various detectors. After a brief explanation of the adopted methodology and formalism, the performance of the Bayesian PID approach for charged pions, kaons and protons in the central barrel of ALICE is studied. PID is performed via measurements of specific energy loss ($\mathrm{d}E/\mathrm{d}x$) and time-of-flight. PID efficiencies and misidentification probabilities are extracted and compared with Monte Carlo simulations using high-purity samples of identified particles in the decay channels ${\rm K}^0_S \righta…
Recomendaciones en el manejo de la pandemia por coronavirus SARS-CoV-2 (Covid-19) en pacientes con trasplante renal
2020
The SARS-CoV-2 (Covid-19) coronavirus pandemic is evolving very quickly and means a special risk for both immunosuppressed and comorbid patients. Knowledge about this growing infection is also increasing although many uncertainties remain, especially in the kidney transplant population. This manuscript presents a proposal for action with general and specific recommendations to protect and prevent infection in this vulnerable population such as kidney transplant recipients. Resumen: La pandemia por coronavirus SARS-CoV-2 (Covid-19) está evolucionando de manera muy rápida y representa un riesgo especial en pacientes inmunodeprimidos y con comorbilidades añadidas. El conocimiento sobre esta in…
Dust-stack 2009 of combined sediment record ELSA
2009
The last glacial cycle in Central Europe is dominated by processes of aeolian dust transport and accumulation. These dust deposits are preserved in soils and lake sediments and provide detailed information about the climate variability during cold and dry periods. Especially the transitions from warm into cold periods are characterized by turbulent climate conditions. The main problems of terrestrial paleoclimate reconstructions are the completeness of the core material and a sampling resolution. To detect single dust storms we use a particle detection method, which allows high resolution, sub-annual analyses of sediment structures in undisturbed samples. The ELSA (Eifel Laminated Sediment …
Dust-stack 2013 of combined sediment record ELSA
2013
During the last twelve years the ELSA Project (Eifel Laminated Sediment Archive) at Mainz University has drilled a total of about 52 cores from 27 maar lakes and filled-in maar basins in the Eifel/Germany. Dating has been completed for the Holocene cores using 6 different methods (210Pb and 137Cs activities, palynostratigraphy, event markers, varve counting, 14C). In general, the different methods consistently complement one another within error margins. Event correlation was used for relating typical lithological changes with historically known events such as the two major Holocene flood events at 1342 AD and ca 800 BC. Dating of MIS2?MIS3 core sections is based on greyscale tuning, radioc…
Predictive distributions that mimic frequencies over a restricted subdomain
2020
A predictive distribution over a sequence of $$N+1$$ events is said to be “frequency mimicking” whenever the probability for the final event conditioned on the outcome of the first N events equals the relative frequency of successes among them. Exchangeable distributions that exhibit this feature universally are known to have several annoying concomitant properties. We motivate frequency mimicking assertions over a limited subdomain in practical problems of finite inference, and we identify their computable coherent implications. We provide some examples using reference distributions, and we introduce computational software to generate any complete specification desired. Theorems on reducti…
Archetypal analysis: an alternative to clustering for unsupervised texture segmentation
2019
Texture segmentation is one of the main tasks in image applications, specifically in remote sensing, where the objective is to segment high-resolution images of natural landscapes into different cover types. Often the focus is on the selection of discriminant textural features, and although these are really fundamental, there is another part of the process that is also influential, partitioning different homogeneous textures into groups. A methodology based on archetype analysis (AA) of the local textural measurements is proposed. AA seeks the purest textures in the image and it can find the borders between pure textures, as those regions composed of mixtures of several archetypes. The prop…
Dynamic stability of plane elastic frames
1982
Abstract The stability of plane elastic frames subjected to a vertical foundation motion of the stationary, ergodic type is investigated. The equations of motion are obtained in modal co-ordinates, with account taken of many modes of vibration. The problem is subsequently reduced to the study of only the first mode of vibration. By considering a particular case, the stability domains are sketched as functions of the variation of the rigidities of the beam-column connecting joints and as functions of the number of stories.
Value preserving portfolio strategies and the minimal martingale measure
1998
We consider some relations between the minimal martingale measure and the value preserving martingale measure in a continuous-time securities market. Under the assumption of continuous share prices we show that under a structure condition both these martingale measures exist and indeed coincide. This however does not mean that the corresponding concepts of value preserving portfolio strategies and (local) risk minimisation in the area of option hedging in incomplete markets are identical.