Search results for "Process"
showing 10 items of 22310 documents
Understanding Estonian phraseological units on the basis of Finnish : contributing and misleading factors
2020
Vironkielistä tekstiä lukevien suomalaisten on havaittu hyödyntävän monenlaisia strategioita selvittääkseen sukukielen sanojen merkityksiä. Yksi niistä on pohjustaminen (priming). Kun kyseessä on fraseologinen yksikkö, yksi osa (prime) pohjustaa toisen osan eli kohdesanan (targetin) esiintymistä, mikäli prime on tunnistettavissa äidinkielen perusteella. Tässä artikkelissa kuvaamme muutamia erityistilanteita. Miten pohjustimen ja kohdesanan välinen etäisyys tai teemanvaihdos vaikuttavat ’petollisen ystävän’ ymmärtämiseen? Lisäksi tutkimme sitä, miten ahdasrajainen semanttinen kategoria ohjaa siitä puuttuvan jäsenen merkityksen löytämistä ja millaisia perusteita käännösratkaisuille on löydett…
Suomi ja viro oppijan mielessä : näkökulmia taivutusmuotojen prosessointiin
2006
Kielenoppijan äidinkielen eli lähdekielen (L1) ja opittavan kielen eli kohdekielen (L2) rakenteita ja sanastoa vertaillaan usein toisiinsa, koska havaittujen erojen ja yhtäläisyyksien oletetaan olevan jossakin suhteessa kielenoppimisen kulkuun ja oppijoiden kielellisiin tuotoksiin. Oletus perustuu käytännön kokemuksiin, mutta enenevästi myös tutkimustietoon (ks. erityisesti Kaivapalu 2005). Lähde- ja kohdekielen suhteen olemuksen tutkimuksellinen määritteleminen on kuitenkin haastavampi ja mutkikkaampi tehtävä kuin pelkkä kielten ja oppijoiden puheen ja kirjoituksen vertailu. peerReviewed
Designing a graphics processing unit accelerated petaflop capable lattice Boltzmann solver: Read aligned data layouts and asynchronous communication
2016
The lattice Boltzmann method is a well-established numerical approach for complex fluid flow simulations. Recently, general-purpose graphics processing units (GPUs) have become available as high-performance computing resources at large scale. We report on designing and implementing a lattice Boltzmann solver for multi-GPU systems that achieves 1.79 PFLOPS performance on 16,384 GPUs. To achieve this performance, we introduce a GPU compatible version of the so-called bundle data layout and eliminate the halo sites in order to improve data access alignment. Furthermore, we make use of the possibility to overlap data transfer between the host central processing unit and the device GPU with com…
CVB3 VP1 interacts with MAT1 to inhibit cell proliferation by interfering with Cdk-activating kinase complex activity in CVB3-induced acute pancreati…
2021
Coxsackievirus B3 (CVB3) belongs to the genus Enterovirus of the family Picornaviridae and can cause acute acinar pancreatitis in adults. However, the molecular mechanisms of pathogenesis underlying CVB3-induced acute pancreatitis have remained unclear. In this study, we discovered that CVB3 capsid protein VP1 inhibited pancreatic cell proliferation and exerted strong cytopathic effects on HPAC cells. Through yeast two-hybrid, co-immunoprecipitation, and confocal microscopy, we show that Menage a trois 1 (MAT1), a subunit of the Cdk-Activating Kinase (CAK) complex involved in cell proliferation and transcription, is a novel interaction protein with CVB3 VP1. Moreover, CVB3 VP1 inhibited MAT…
The Extracellular δ-Domain is Essential for the Formation of CD81 Tetraspanin Webs
2014
AbstractCD81 is a ubiquitously expressed member of the tetraspanin family. It forms large molecular platforms, so-called tetraspanin webs that play physiological roles in a variety of cellular functions and are involved in viral and parasite infections. We have investigated which part of the CD81 molecule is required for the formation of domains in the cell membranes of T-cells and hepatocytes. Surprisingly, we find that large CD81 platforms assemble via the short extracellular δ-domain, independent from a strong primary partner binding and from weak interactions mediated by palmitoylation. The δ-domain is also essential for the platforms to function during viral entry. We propose that, ins…
Characterization of the autoantigen La (SS-B) as a dsRNA unwinding enzyme
1997
During the analysis of the La (SS-B) autoantigen for catalytic activities an ATP-dependent double-stranded RNA unwinding activity was detected. Both native and recombinant La proteins from different species displayed this activity, which could be inhibited by monospecific anti-La antibodies. La protein was able to melt dsRNA substrates with either two 3'-overhangs or a single 3'- and a 5'-overhang. Double-stranded RNAs with two 5'-overhangs were not unwound, indicating that at least one 3'-overhang is required for unwinding. Sequence elements of the La protein that might be involved in dsRNA unwinding, such as an evolutionarily conserved putative ATP-binding motif and an element that is hom…
The ALICE experiment at the CERN LHC
2008
Journal of Instrumentation 3(08), S08002 (2008). doi:10.1088/1748-0221/3/08/S08002
Conception en technologie CMOS d'un Système de Vision dédié à l'Imagerie Rapide et aux Traitements d'Images
2008
Our work presented in this thesis focuses on the design, testing and implementation of monolithics CMOS image smart sensors : The principle, performance and limitations. The hardware implementation of a vision smart system is the central link. HISIC is High Speed Image Capture with processing at pixel level. An experimental platform for instrumentation and evaluation of retina operators was conducted during this thesis. After a state of the smart sensors and CMOS retinas, the second part is dedicated to the study and design of the pixel image sensor HISIC. Two circuits were realized in CMOS technology. The first identied a new type of photo-detector, and the second, to create a prototype em…
Brain's capacity to detect abstract regularities from visual stimuli under different attentive conditions- an ERP study
2010
Many previous studies have applied oddball paradigm to study change detection. Although changes within single features have been investigated a lot, the changes in multiple feature conjunctions have not. The aim of our study was to investigate with event-related potentials by applying oddball paradigm, whether the brain can detect abstract regularities in visual stimulus stream when two different features are combined - semantic meaning and color. Participants were shown adjective words written in red and blue print in quasi-random order on a computer screen. In an oddball paradigm, 90 % of the words (‘standard’) followed the rule “words printed in red have a negative meaning and the words …