Search results for "Processe"

CVB3 VP1 interacts with MAT1 to inhibit cell proliferation by interfering with Cdk-activating kinase complex activity in CVB3-induced acute pancreati…

2021

Coxsackievirus B3 (CVB3) belongs to the genus Enterovirus of the family Picornaviridae and can cause acute acinar pancreatitis in adults. However, the molecular mechanisms of pathogenesis underlying CVB3-induced acute pancreatitis have remained unclear. In this study, we discovered that CVB3 capsid protein VP1 inhibited pancreatic cell proliferation and exerted strong cytopathic effects on HPAC cells. Through yeast two-hybrid, co-immunoprecipitation, and confocal microscopy, we show that Menage a trois 1 (MAT1), a subunit of the Cdk-Activating Kinase (CAK) complex involved in cell proliferation and transcription, is a novel interaction protein with CVB3 VP1. Moreover, CVB3 VP1 inhibited MAT…

Characterization of the autoantigen La (SS-B) as a dsRNA unwinding enzyme

1997

During the analysis of the La (SS-B) autoantigen for catalytic activities an ATP-dependent double-stranded RNA unwinding activity was detected. Both native and recombinant La proteins from different species displayed this activity, which could be inhibited by monospecific anti-La antibodies. La protein was able to melt dsRNA substrates with either two 3'-overhangs or a single 3'- and a 5'-overhang. Double-stranded RNAs with two 5'-overhangs were not unwound, indicating that at least one 3'-overhang is required for unwinding. Sequence elements of the La protein that might be involved in dsRNA unwinding, such as an evolutionarily conserved putative ATP-binding motif and an element that is hom…

The ALICE experiment at the CERN LHC

2008

Journal of Instrumentation 3(08), S08002 (2008). doi:10.1088/1748-0221/3/08/S08002

Noble gases in tracking volcanic processess

2007

The expressions able to evaluate the contributions of the three natural sources of helium (e.g., atmosphere,in magma, following the solubility model proposed by Nuccio and Paonita (2001). In particular, variations of He/Ne and He/CO2 ratios have been used to compute the initial and final pressure of an ascending magma (Fig. 2) (Caracausi et alii 2003b, Rizzo et alii 2006). This model was subsequently implemented with S, Cl and F (Aiuppa et alii 2004), providing an useful geochemical tool aimed at giving an early warning for forecasting volcanic eruptions. The high helium flux measured at Mefite d’Ansanto in the Irpinian Apennines, displaying a He isotope composition analogous to that of Mt.…

Anticipatory Postural Adjustments and kinematic arm features when postural stability is manipulated

2018

International audience; Beyond the classical paradigm that presents the Anticipatory Postural Adjustments (APAs) as a manner to create forces that counteract disturbances arising from the moving segment during a pointing task, there is a controversial discussion about the role APAs to facilitate the movement and perform a task accurately. In addition, arm kinematics features are classically used to infer the content of motor planning for the execution and the control of arm movements, The present study aimed to disentangle the conflicting role of APAs during an arm-pointing task in which the subjects reach a central diode that suddenly turns on, while their postural stability was manipulate…

Dyvalocca : un projet pour l'étude des nuages bas de saison sèche sur la façade atlantique de l'Afrique centrale et de leur impact bioclimatique sur …

2020

Low-level clouds are key components of the climate but are not well represented in weather and climate models. Recently it has been shown that an extensive low-level cloud cover develops during the June-September main dry season in western equatorial Africa, from the coastal plains of Gabon and Congo-Brazzaville to the inland plateaus downstream of the low-mountain crests. Such a cloudy main dry season is unique in the moist Tropics and is likely to explain the presence of the densest and evergreen forests of Central Africa as evapotranspiration is low and the quality of light is high. The ANR-DFG funded “DYVALOCCA” project will conduct from 2020 to 2022 a field campaign, raise existing in-…

Welded section defence by LRPD devices

2023

The present paper concerns a special application of some recently proposed structural devices, called LRPD, able to protect the welded sections of frame steel structures from undesired brittle collapse ensuring the good expected ductile behaviour. Standard I-shaped cross-sections are treated, and the proposed devices are suitably considered as moment resisting connections between beams and columns. At first the domain representing the brittle safe conditions is defined in the N,V,M space; then a sample plane frame subjected to seismic load conditions is studied and it is proved that, equipping the structure with the proposed devices suitably designed, the generalized stresses at the welded …

TESS_ Territorial Empowerment & Social Sustainability: un’esperienza triennale tra paesaggi culturali e partecipazione.

2015

Analysis of the Potential of an Increase in Yeast Output Resulting from the Application of Additional Process Wastewater in the Evaporator Station

2019

This paper reports the results of an analysis of process wastewater streams in the context of an increase in yeast production. This research is based on the analysis of data from the biggest yeast factory in Europe. The research presented in this paper involves the analysis of the influence of direction of additional wastewater into the evaporator station on yeast production. In the process wastewater, nitrogen is mainly present in organic forms. The analysis reported in this paper involves the concentration of total nitrogen in wastewater streams, as it is the main parameter applied to determine the amount of wastewater that can be applied in agricultural fields. Directing additional waste…

Consumption of ultra-processed foods : an assessment of the literature on determinants of ultra-processed food consumption and an investigation of th…

2016

Masteroppgave folkehelsevitenskap - Universitetet i Agder 2016 Background Highly processed foods have been classified as ultra-processed, and consumption of such foodstuffs have expanded rapidly over the last decades. Ultra-processed foods are characterized as being accessible, attractive, palatable and often time-saving. An excess intake of ultra-processed foods has been associated with increased risk of e.g. overweight/obesity and diabetes type II. The aim of this master’s project was to investigate factors influencing consumption of ultra-processed foods. This resulted in one review paper on young adults, and one cross-sectional study where the association between time scarcity and ultra…