Search results for "Processes"

showing 10 items of 3831 documents

p38 MAPK: A dual role in hepatocyte proliferation through reactive oxygen species

2013

p38 MAPKs are important mediators of signal transduction that respond to a wide range of extracellular stressors such as UV radiation, osmotic shock, hypoxia, pro-inflammatory cytokines, and oxidative stress. The most abundant family member is p38α, which helps to couple cell proliferation and growth in response to certain damaging stimuli. In fact, increased proliferation and impaired differentiation are hallmarks of p38α-deficient cells. It has been reported that reactive oxygen species (ROS) play a critical role in cytokine-induced p38α activation. Under physiological conditions, p38α can function as a mediator of ROS signaling and either activate or suppress cell cycle progression depen…

chemistry.chemical_classificationMAPK/ERK pathwayReactive oxygen speciesMAP Kinase Signaling SystemCell growthp38 mitogen-activated protein kinasesCell Growth ProcessesGeneral MedicineCell cycleBiologymedicine.disease_causep38 Mitogen-Activated Protein KinasesBiochemistryLiver regenerationCell biologychemistryHepatocytesmedicineAnimalsHumansSignal transductionReactive Oxygen SpeciesOxidative stressFree Radical Research
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Cementing agents involved in the macro- and microaggregation of a Mediterranean shrubland soil under laboratory heating

2014

The heating effect on aggregation and cementing agents of a Mediterranean soil was studied in two fractions (macro- and microaggregates) in different environments: under Quercus coccifera soil (UQ), under Rosmarinus officinalis soil (UR) and between plants or bare soil (BS). Samples were heated under laboratory conditions at different temperatures (220, 380, 500, 750 and 1000. °C) to establish their effects on the studied soil properties by comparison with unheated control samples (25. °C). Increasing temperature treatments caused significant changes in most soil variables. In both soil fractions, the presence of vegetation contributed to increase of the soil organic matter (SOM) content, w…

chemistry.chemical_classificationMediterranean climateCanopySoil organic mattergeographygeography.geographical_feature_categorybiologySoil organic matterExtractable ironSoil scienceCalcium carbonatesMean weight diameterFireAggregate stabilitybiology.organism_classificationShrublandchemistry.chemical_compoundCalcium carbonatechemistryEnvironmental chemistrySoil waterOrganic matterQuercus cocciferaEarth-Surface ProcessesCATENA
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Spatial and short-term temporal variations in runoff, soil aggregation and other soil properties along a Mediterranean Climatological Gradient.

1998

Abstract Physical and chemical soil properties were measured along a mountainous climatological gradient in the province of Alicante (Spain). The objective was to evaluate how the climate affects certain soil properties at different temporal and spatial scales. These properties include infiltration, runoff and sediment concentrations resulting from rainfall simulation experiments performed in winter and in summer. Chemical soil properties like carbonate content, organic matter content and CEC were analysed in reference soil profiles along the gradient. Physical soil properties like soil moisture content, macroaggregation and waterstable microaggregation were measured at monthly intervals du…

chemistry.chemical_classificationMediterranean climateHydrologySoil morphologySoil sciencecomplex mixturesAridInfiltration (hydrology)Pedotransfer functionchemistryEnvironmental scienceOrganic matterWEPPSurface runoffEarth-Surface Processes
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The Quest for Mononuclear Gold(II) and Its Potential Role in Photocatalysis and Drug Action.

2017

The chemistry of gold strongly focuses on the ubiquitous oxidation states +I and +III. The intermediate oxidation state +II is generally avoided in mononuclear gold species. In recent years, gold(II) has been increasingly suggested as a key intermediate in artificial photosynthesis systems, with gold(III) moieties acting as electron acceptors, as well as in gold-catalyzed photoredox catalysis and radical chemistry. This Minireview provides a concise summary of confirmed and characterized mononuclear open-shell gold(II) complexes. Recent findings on structural motifs and reactivity patterns will be discussed. Exciting developments in the fields of photosynthesis, photocatalysis, and potentia…

chemistry.chemical_classificationMolecular Structure010405 organic chemistryChemistryRadicalChemistry PharmaceuticalPhotoredox catalysisElectronsGeneral ChemistryElectron acceptor010402 general chemistryPhotochemical Processes01 natural sciencesCombinatorial chemistryCatalysis0104 chemical sciencesArtificial photosynthesisElectron transferOxidation statePhotocatalysisOrganic chemistryReactivity (chemistry)Organogold CompoundsAngewandte Chemie (International ed. in English)
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Calculation of the Phase Behavior of Lipids

1998

The self-assembly of monoacyl lipids in solution is studied employing a model in which the lipid's hydrocarbon tail is described within the Rotational Isomeric State framework and is attached to a simple hydrophilic head. Mean-field theory is employed, and the necessary partition function of a single lipid is obtained via a partial enumeration over a large sample of molecular conformations. The influence of the lipid architecture on the transition between the lamellar and inverted-hexagonal phases is calculated, and qualitative agreement with experiment is found.

chemistry.chemical_classificationPartition function (quantum field theory)Quantitative Biology::BiomoleculesStatistical Mechanics (cond-mat.stat-mech)010304 chemical physicsChemistryFOS: Physical sciencesThermodynamics02 engineering and technology021001 nanoscience & nanotechnology01 natural sciencesMolecular conformationLarge sampleQuantitative Biology::Subcellular ProcessesCondensed Matter::Soft Condensed MatterHydrocarbonPhase (matter)0103 physical sciencesLamellar structurelipids (amino acids peptides and proteins)Lipid bilayer phase behavior0210 nano-technologyCondensed Matter - Statistical Mechanics
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Polymer-induced shape changes and capping in giant liposomes

1995

We studied the coupling of a polymeric amphiphile undergoing a transition from an expanded to a collapsed state of the hydrophilic polymer chain upon heating above 29°C with free and solid supported lipid bilayers. Lateral diffusion measurements and studies of vesicle shape-changes confirmed previous calorimetric studies, suggesting that the amphiphile remains incorporated in the giant vesicles and the supported bilayer during the transition. The two-dimensional hydrodynamic radii of the amphiphile in the expanded and collapsed state was measured by making use of the strong quadratic dependence of the diffusion coefficient on the radius of the diffusant (D ∞ r−2) due to the frictional coupl…

chemistry.chemical_classificationPhysics::Biological PhysicsLiposomeHydrodynamic radiusVesicleBilayerDiffusionOrganic ChemistryAnalytical chemistryCell BiologyPolymerBiochemistryQuantitative Biology::Subcellular ProcessesCondensed Matter::Soft Condensed MatterchemistryChemical physicsAmphiphilesense organsLipid bilayerMolecular BiologyChemistry and Physics of Lipids
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Research on the Diurnal Courses of Abscissic Acid, 1-Aminocyclopropane Carboxylic Acid and Its Malonyl Conjugate Contents in Needles of Damaged and U…

1993

Ethylene regulates many aspects of plant growth, development and senescence. The immediate precursor of ethylene was identified as 1-aminocyclopropane carboxylic acid (ACC) [7]. Amrhein et al. [1] discovered that ACC supplied exogenously was efficiently converted into ACC malonyl conjugate (MACC) along with ethylene production.

chemistry.chemical_classificationPlant growthEthyleneStereochemistryCarboxylic acidAbscissic Acidbehavioral disciplines and activitiesstomatognathic diseaseschemistry.chemical_compoundnervous systemchemistryBiochemistryhuman activitiespsychological phenomena and processesConjugate
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Are polymers suitable rock analogs?

2002

To evaluate if a polymer is suitable for analog modeling, it is essential to know the rheological properties of the material. Polymers used in analog modeling exhibit a complex rheological behavior; only part of which has been taken into account in most modeling studies. The mechanical behavior is strongly dependent on strain rate and temperature, and is characterized by specific dependencies of the storage and loss moduli, related to the elasticity and viscosity, on the deformation rate (frequency). We have measured the storage and loss moduli at a broad range of strain rates and strains, using an oscillatory parallel-disk rheometer. Investigated materials are polydimethylsiloxane (PDMS), …

chemistry.chemical_classificationPolydimethylsiloxaneRheometerPolymerStrain rateCondensed Matter::Soft Condensed MatterViscositychemistry.chemical_compoundGeophysicschemistryRheologyNewtonian fluidElasticity (economics)Composite materialGeologyEarth-Surface ProcessesTectonophysics
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Translocation dynamics of a short polymer driven by an oscillating force

2013

Under the terms of the Creative Commons Attribution 3.0 Unported License.

chemistry.chemical_classificationQuantitative Biology::BiomoleculesField (physics)Polymersmedia_common.quotation_subjectDynamics (mechanics)General Physics and AstronomyMonotonic functionPolymerFunction (mathematics)InertiaSettore FIS/07 - Fisica Applicata(Beni Culturali Ambientali Biol.e Medicin)Settore FIS/03 - Fisica Della MateriaQuantitative Biology::Subcellular ProcessesCondensed Matter::Soft Condensed MatterLangevin equationchemistryChemical physicsMetastabilityPolymer translocation Complex Systems Langevin equation Stochastic modelingThermodynamicsStatistical physicsPhysical and Theoretical Chemistrymedia_common
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Counterion-mediated attraction and kinks on loops of semiflexible polyelectrolyte bundles.

2006

The formation of kinks in a loop of bundled polyelectrolyte filaments is analyzed in terms of the thermal fluctuations of charge density due to polyvalent counterions adsorbed on the polyelectrolyte filaments. It is found that the counterion-mediated attraction energy of filaments depends on their bending. By consideration of curvature elasticity energy and counterion-mediated attraction between polyelectrolyte filaments, the characteristic width of the kink and the number of kinks per loop is found to be in reasonable agreement with existing experimental data for rings of bundled actin filaments.

chemistry.chemical_classificationQuantitative Biology::BiomoleculesMaterials scienceCondensed matter physicsMolecular ConformationGeneral Physics and AstronomyThermal fluctuationsCharge densityBendingCurvatureAttractionPolyelectrolyteActinsQuantitative Biology::Cell BehaviorQuantitative Biology::Subcellular ProcessesCondensed Matter::Soft Condensed MatterActin CytoskeletonElectrolyteschemistryModels ChemicalChemical physicsThermodynamicsCounterionElasticity (economics)Physical review letters
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