Search results for "Production"

Type V collagen-induced upregulation of capn2 (large subunit of m-calpain) gene expression and DNA fragmentation in 8701-BC breast cancer cells

2011

Abstract Type V collagen is known to be over-deposited in the stroma of ductal infiltrating carcinomas of the breast. When used as a substrate, type V collagen restrains growth and invasion, and affects gene expression of 8701-BC ductal infiltrating carcinomas cells. Here we supplement existing data by demonstrating type V collagen dependent upregulation of capn2 gene expression in 8701-BC cells through differential display-PCR and Western blot assays. Furthermore, we suggest that our data obtained by centrifugal sedimentation and electrophoresis strongly suggest a correlation between calpain overproduction and DNA fragmentation, since the incubation with calpain inhibitor partly reverts th…

Azimuthal anisotropy of charged jet production in √sNN = 2.76 TeV Pb–Pb collisions

2016

We present measurements of the azimuthal dependence of charged jet production in central and semicentral √sNN = 2.76 TeV Pb–Pb collisions with respect to the second harmonic event plane, quantified as vch jet 2 . Jet finding is performed employing the anti-kT algorithm with a resolution parameter R = 0.2 using charged tracks from the ALICE tracking system. The contribution of the azimuthal anisotropy of the underlying event is taken into account event-by-event. The remaining (statistical) region-to-region fluctuations are removed on an ensemble basis by unfolding the jet spectra for different event plane orientations independently. Significant non-zero vch jet 2 is observed in semi-central …

Centrality dependence of particle production in p−Pb collisions at √sNN = 5.02 TeV

2015

We report measurements of the primary charged-particle pseudorapidity density and transverse momentum distributions in p-Pb collisions at √sNN = 5.02 TeV and investigate their correlation with experimental observables sensitive to the centrality of the collision. Centrality classes are defined by using different event-activity estimators, i.e., charged-particle multiplicities measured in three different pseudorapidity regions as well as the energy measured at beam rapidity (zero degree). The procedures to determine the centrality, quantified by the number of participants (Npart) or the number of nucleon-nucleon binary collisions (Ncoll) are described. We show that, in contrast to Pb-Pb coll…

The Beginning of Western Greek Amphorae Production in Western Sicily: Archaeometric and Archaeological Studies on 6th–5th Centuries BCE Amphorae Manu…

2020

About 560 western Greek amphorae (6th–5th centuries BCE) re-used in enchytrismos burials were unearthed in the necropolis of the Dorian-Chalcidian colony of Himera in northwestern Sicily. Among the most striking issues is the determination of their geographical provenance. For this purpose, ceramic samples chipped from freshly broken surfaces of all the amphorae were first subdivided into macrofabrics by the use of a hand lens. Thereon, the samples were studied in accordance with standardized methods by the use of reflected light microscopy. Due to the special focus of our project on the characterization of Sicilian productions, a selection of amphorae which showed visible, macroscopic affi…

Effect of the dam’s feeding regimen on the meat quality of light suckling lambs

2010

In order to verify the effect of the introduction of concentrates without GMO risk and at low aflatoxin risk in the diet of grazing milk ewes on the quanti-qualitative production of meat of their milk-fed light lambs, two trials were carried out - in Sicily, on 32 Comisana lambs, slaughtered at 49±4 days (trial 1); and in Sardinia, on 28 Sarda lambs, slaughtered at 31±4 days(trial 2) - comparing the following grazing dams’ feeding regimes: High stocking rate + Organic (barley – tickbean or pea) Concentrate (HO); High stocking rate + Conventional (maize-soybean) Concentrate (HC); Low stocking rate + Organic Concentrate (LO); Low stocking rate + Conventional Concentr…

Synthesis and optimization of microwave-assisted exfoliated functionalized graphene as an efficient catalyst in biodiesel production

2018

In this study, the capability of functionalized graphene was investigated as heterogeneous catalyst in biodiesel production from vegetable oil. Graphene oxide was fabricated from graphite via carrier improved method, and its exfoliation was carried out by microwave radiation. The exfoliated sample was reduced and sulfonated, being analyzed by Fourier transform Infrared, Scanning Microscopy Transmission Electron Microscopy, X-ray diffraction and element mapping. The catalyst was employed in biodiesel production reaction and effective reaction parameters were studied. The optimized reaction temperature, time and catalyst percentage were 178 °C, 3 h and 1.9% respectively. It was observed that …

Challenges and Opportunities for the Encapsulation of Enzymes over Porous Solids for Biodiesel Production and Cellulose Valorization into Glucose

2021

ChemInform Abstract: The Synthesis and Effect of Fluorinated Chalcone Derivatives on Nitric Oxide Production.

2010

Abstract Dimethoxy- and trimethoxychalcone derivatives, with various patterns of fluorination, were synthesized and evaluated for their influence on nitric oxide production. Some of them, chalcones 1 , 5 , 7 , 10 , 11 and 17 , inhibited NO production with an IC 50 in the submicromolar range; 17 is especially noteworthy because of its potency (IC 50 30 nM). These effects were not the consequence of a direct inhibitory action on enzyme activity but the inhibition of enzyme expression.

Aptamer-based assay of biomolecules: Recent advances in electro-analytical approach

2017

Electrochemical aptasensors, which are based on the specificity of aptamer-target recognition, with electrochemical transduction for analytical purposes have received particular attention due to their high sensitivity and selectivity, simple instrumentation, as well as low production cost. This review summarizes advances from 2009 to January 2017 in the development of electrochemical aptasensors for biological molecules, including small molecules, nucleic acids, and proteins. Various aptasensing strategies are assessed according to their potential for reaching relevant limits of sensitivity, specificity, and degrees of multiplexing. Furthermore, we address the remaining challenges and oppor…

Effect of ewe feeding system (grass v. concentrate) on intramuscular fatty acids of lambs raised exclusively on maternal milk

2005

AbstractTwenty pregnant Comisana ewes were divided into two groups of 10. One group was allowed to graze a vetch pasture (grass). The second group of animals was housed collectively in a pen and was given hay and concentrates (concentrate). After lambing, all the ewes were allowed to stay with the respective lambs between 18:00 h and 07:00 h of the following day in two different pens. Therefore all the lambs were raised exclusively on maternal milk. The lambs were slaughtered at 38 days of age. Milk and lamb meat (longissimus dorsi muscle) fatty acids were analysed. Ewes on grass produced milk with a lower (P< 0·001) proportion of saturated fatty acids and with a higher proportion of bot…