Search results for "Program"
showing 10 items of 5938 documents
Categorization of Extremely Brief Auditory Stimuli: Domain-Specific or Domain-General Processes?
2011
The present study investigated the minimum amount of auditory stimulation that allows differentiation of spoken voices, instrumental music, and environmental sounds. Three new findings were reported. 1) All stimuli were categorized above chance level with 50 ms-segments. 2) When a peak-level normalization was applied, music and voices started to be accurately categorized with 20 ms-segments. When the root-mean-square (RMS) energy of the stimuli was equalized, voice stimuli were better recognized than music and environmental sounds. 3) Further psychoacoustical analyses suggest that the categorization of extremely brief auditory stimuli depends on the variability of their spectral envelope in…
Analysis and Optimization Technique of Secure Smart Grid Communication Network for Sustainable Development
2019
The smart network includes many sub-frameworks, for example, the Home Area Network (HAN), which are at risk and prone to be attacked remotely. A smart grid communication is meant to design a mutual authentication scheme and a key management protocol. This study is aimed with an efficient arrangement for HAN that analyzes a framework set-up for HAN. In this paper, we have analyzed three cases: First, we show the normal execution then execution along with attackers. Using mutual authentication, we overcome attacks. It has introduced a number of routing schemes for grid networks in recent years, and they provide different level of privacy protection at different cost. First, an unspecified key…
A Multi-Expert Based Approach to Continuous Authentication of Mobile-Device Users
2003
Currently used in mobile devices PIN-based user authentication cannot provide a sufficient security level. Methods based on multi-modal user authentication involving biometrics (i.e. physical and behavioral characteristics of a person) may be employed to cope with this problem. However, dealing with physical characteristics only, these methods are either unable to provide continuous and user-friendly identity verification, or are resource consuming.
Attacks Against the WAP WTLS Protocol
1999
The WAP WTLS protocol was designed to provide privacy, data integrity, and authentication for wireless terminals. The protocol is currently being fielded, and it is expected that the protocol will be contained in millions of devices in a few years.
Database Versioning 2.0, a Transparent SQL Approach Used in Quantitative Management and Decision Making
2015
Abstract Managerial decisions are based on accurate information and in today's time raw data is produced even with a stroke of a key. Regardless of the data creating process one needs to know how the information was extracted and which pool of data was used. One important factor is time therefore we need to structure it in layers of data history in such a way that it can be analyzed, (post)process, in order to be able to retrieve valuable information. The simplest way is to use a Database Management System (DBMS), but even with such a management system we face the issue of making it a self-contained database on each version of data added. Our proposed system, a continuation of previous work…
Diabētiskās retinopātijas skrīnings optometrista praksē
2020
Maģistra darbs uzrakstīts latviešu valodā uz 46 lapām, satur 21 attēlu, 12 tabulas, 2 pielikumus un 105 atsauces uz literatūras avotiem. Darba mērķis: novērtēt optometristu un automātiskās skrīninga programmatūras prasmes atpazīt diabētiskās retinopātijas pazīmes. Pētījuma dalībnieki: pētījumā piedalījās 2 oftalmologi, 14 optometristi un automatizētā skrīninga programmatūra AI Avenue. Metode: 196 tīklenes attēliem tika veikts skrīninga tests atbilstoši starptautiskās diabētiskās retinopātijas klasifikācijai. Rezultāti: Rekomendēto testa standartu – jutība un specifiskums ≥ 80% sasniedza oftalmologs un 2 optometristi. AI Avenue sasniedza vienīgi rekomendēto testa specifiskumu. Secinājumi: AI…
Artesunate Activates Mitochondrial Apoptosis in Breast Cancer Cells via Iron-catalyzed Lysosomal Reactive Oxygen Species Production
2011
The antimalarial agent artesunate (ART) activates programmed cell death (PCD) in cancer cells in a manner dependent on the presence of iron and the generation of reactive oxygen species. In malaria parasites, ART cytotoxicity originates from interactions with heme-derived iron within the food vacuole. The analogous digestive compartment of mammalian cells, the lysosome, similarly contains high levels of redox-active iron and in response to specific stimuli can initiate mitochondrial apoptosis. We thus investigated the role of lysosomes in ART-induced PCD and determined that in MCF-7 breast cancer cells ART activates lysosome-dependent mitochondrial outer membrane permeabilization. ART impac…
p62: Friend or Foe? Evidences for OncoJanus and NeuroJanus Roles
2020
p62 is a versatile protein involved in the delicate balance between cell death and survival, which is fundamental for cell fate decision in the context of both cancer and neurodegenerative diseases. As an autophagy adaptor, p62 recognizes polyubiquitin chains and interacts with LC3, thereby targeting the selected cargo to the autophagosome with consequent autophagic degradation. Beside this function, p62 behaves as an interactive hub in multiple signalling including those mediated by Nrf2, NF-κB, caspase-8, and mTORC1. The protein is thus crucial for the control of oxidative stress, inflammation and cell survival, apoptosis, and metabolic reprogramming, respectively. As a multifunctional pr…
Autophagy in development and stress responses of plants.
2006
The uptake and degradation of cytoplasmic material by vacuolar autophagy in plants has been studied extensively by electron microscopy and shown to be involved in developmental processes such as vacuole formation, deposition of seed storage proteins and senescence, and in the response of plants to nutrient starvation and to pathogens. The isolation of genes required for autophagy in yeast has allowed the identification of many of the corresponding Arabidopsis genes based on sequence similarity. Knockout mutations in some of these Arabidopsis genes have revealed physiological roles for autophagy in nutrient recycling during nitrogen deficiency and in senescence. Recently, markers for monitor…
Involvement of PAR-4 in Cannabinoid-Dependent Sensitization of Osteosarcoma Cells to TRAIL-Induced Apoptosis
2014
The synthetic cannabinoid WIN 55,212-2 is a potent cannabinoid receptor agonist with anticancer potential. Experiments were performed to determine the effects of WIN on proliferation, cell cycle distribution, and programmed cell death in human osteosarcoma MG63 and Saos-2 cells. Results show that WIN induced G2/M cell cycle arrest, which was associated with the induction of the main markers of ER stress (GRP78, CHOP and TRB3). In treated cells we also observed the conversion of the cytosolic form of the autophagosome marker LC3-I into LC3-II (the lipidated form located on the autophagosome membrane) and the enhanced incorporation of monodansylcadaverine and acridine orange, two markers of t…