Search results for "Project"

showing 10 items of 3466 documents

Anesthetic efficacy of ketamine-diazepam, ketamine-xylazine, and ketamine-acepromazine in Caspian Pond turtles (Mauremys caspica)

2017

Objectives: The objective of this study was to assess the efficacy of different anesthetic drug combinations on the Caspian Pond turtles (Mauremys caspica). Subjects and Methods: Three groups of the Caspian Pond turtles (n = 6) were anesthetized with three different drug combinations. Initially, a pilot study was conducted to determine the best drug doses for the anesthetization of the turtles, and according to these results, ketamine-diazepam (120 mg/kg ketamine hydrochloride [5%] and 2 mg/kg diazepam [5%]), ketamine-acepromazine (120 mg/kg ketamine hydrochloride [5%] and 1 mg/kg acepromazine [1%]), and ketamine-xylazine (120 mg/kg ketamine hydrochloride [5%] and 1 mg/kg xylazine [2%]) wer…

MaleXylazinePharmacologyDiazepamketamineDose-Response Relationship DrugTime FactorAnimalAnestheticSex FactorInjections IntramuscularTurtleAnesthesia Recovery PeriodFemalePilot ProjectPharmacology (medical)Mauremys caspicaAcepromazine
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Effects of mini trampoline exercise on male gymnasts' physiological parameters: a pilot study

2014

WOS: 000365060600005

MaleYoung AdultAthletic performanceAnthropometryGymnasticsMuscle strengthCase-Control StudiesHumansPilot ProjectsMuscle StrengthAthletic PerformanceExercisetrampoline exercise
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Aortic Function's Adaptation in Response to Exercise-Induced Stress Assessing by 1.5T MRI : A Pilot Study in Healthy Volunteers

2015

AIM:Evaluation of the aortic "elastic reserve" might be a relevant marker to assess the risk of aortic event. Our aim was to compare regional aortic elasticity at rest and during supine bicycle exercise at 1.5 T MRI in healthy individuals. METHODS:Fifteen volunteers (8 men), with a mean age of 29 (23-41) years, completed the entire protocol. Images were acquired immediately following maximal exercise. Retrospective cine sequences were acquired to assess compliance, distensibility, maximum rates of systolic distension and diastolic recoil at four different locations: ascending aorta, proximal descending aorta, distal descending aorta and aorta above the coeliac trunk level. Segmental aortic …

Male[INFO.INFO-IM] Computer Science [cs]/Medical Imaginglcsh:MedicineAorta ThoracicPilot Projects030204 cardiovascular system & hematologyCardiovascular MedicineVascular Medicine030218 nuclear medicine & medical imagingDiagnostic Radiology0302 clinical medicineDiastole[SPI.MECA.BIOM] Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph]Supine PositionMedicine and Health SciencesThoracic aortaPublic and Occupational Healthlcsh:SciencePulse wave velocityAortaMultidisciplinary[ INFO.INFO-IM ] Computer Science [cs]/Medical ImagingRadiology and Imaging[SPI.MECA.BIOM]Engineering Sciences [physics]/Mechanics [physics.med-ph]/Biomechanics [physics.med-ph]Adaptation PhysiologicalHealthy VolunteersSports Science[SDV.MHEP.CSC] Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemPulmonary imagingCardiovascular diseasesDescending aortaVentricular pressureCardiologycardiovascular systemBlood pressureFemaleAnatomyResearch ArticleAdultmedicine.medical_specialtySystoleImaging TechniquesHeart rateCardiologyPulse Wave AnalysisResearch and Analysis Methods03 medical and health sciencesVascular StiffnessMagnetic resonance imaging[SDV.MHEP.CSC]Life Sciences [q-bio]/Human health and pathology/Cardiology and cardiovascular systemStress PhysiologicalDiagnostic Medicinemedicine.arteryInternal medicineAscending aortamedicine[INFO.INFO-IM]Computer Science [cs]/Medical ImagingHumansSystoleExerciseAortabusiness.industrylcsh:RBiology and Life SciencesPhysical ActivityElasticityBlood pressurePhysical FitnessCardiovascular AnatomyBlood Vesselslcsh:QSports and exercise medicinebusiness
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Ischemic stroke: etiologic work-up with multidetector CT of heart and extra- and intracranial arteries

2010

[DOI:\hrefhttps://dx.doi.org/10.1148/radiol.1010080410.1148/radiol.10100804] [PubMed:\hrefhttps://www.ncbi.nlm.nih.gov/pubmed/2106292521062925]; To assess the potential of a single-session multidetector computed tomography (CT) protocol, as compared with established methods, for the etiologic work-up of acute ischemic stroke.\ Patients found to have recently experienced an ischemic stroke were recruited for this prospective study after institutional review board approval was obtained. Each patient was scheduled for two evaluation strategies: (a) a standard approach involving transthoracic echocardiography (TTE) and transesophageal echocardiography (TEE), duplex ultrasonography (US) of the n…

Male[SDV.IB.IMA]Life Sciences [q-bio]/Bioengineering/ImagingContrast MediaPilot Projects030204 cardiovascular system & hematologyBrain IschemiaBrain ischemiaElectrocardiography0302 clinical medicineRisk FactorsProspective StudiesStrokeAged 80 and overUltrasonography Doppler DuplexCerebral infarctionMiddle AgedMagnetic Resonance ImagingWork-upPlaque Atherosclerotic3. Good healthStrokesurgical procedures operativemedicine.anatomical_structureEchocardiographyCerebrovascular CirculationCirculatory systemcardiovascular systemFemaleRadiologyArteryAdultmedicine.medical_specialtySensitivity and SpecificityStatistics NonparametricCentral nervous system disease03 medical and health sciencesmedicineHumansRadiology Nuclear Medicine and imagingcardiovascular diseasesAgedVascular diseasebusiness.industryCoronary ThrombosisCerebral Arteriesmedicine.diseaseIopamidol[SDV.IB.IMA] Life Sciences [q-bio]/Bioengineering/ImagingbusinessTomography X-Ray Computed030217 neurology & neurosurgery
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Randomized double-blind placebo-controlled trial of acetyl-L-carnitine for ALS.

2013

Our objective was to assess the effects of acetyl-L-carnitine (ALC) with riluzole on disability and mortality of amyotrophic lateral sclerosis (ALS). Definite/probable ALS patients, 40-70 years of age, duration 6-24 months, self-sufficient (i.e. able to swallow, cut food/handle utensils, and walk), and with forced vital capacity (FVC) > 80% entered a pilot double-blind, placebo-controlled, parallel group trial and were followed for 48 weeks. ALC or placebo 3 g/day was added to riluzole 100 mg/day. Primary endpoint: number of patients no longer self-sufficient. Secondary endpoints: changes in ALSFRS-R, MRC, FVC and McGill Quality of Life (QoL) scores. Analysis was made in the intention-to-tr…

Maleamyotrophic lateral sclerosisVital CapacityPlacebo-controlled studyPilot ProjectsGastroenterologylaw.inventionRandomized controlled triallawAcetyl-L-carnitineamyotrophic lateral sclerosis; motor neuron disease; randomized trial; acetyl-l-carnitinerandomized trialAmyotrophic lateral sclerosisAcetylcarnitineALS acetyl-L-carnitineNootropic AgentsRiluzoleMiddle AgedRiluzoleTreatment OutcomeNeurologyCombinationDisease Progressionmotor neuron diseaseDrug Therapy CombinationSettore MED/26 - NeurologiaFemaleAcetylcarnitinemedicine.drugAdultmedicine.medical_specialtyAcetyl-L-carnitine amyotrophic lateral sclerosis motor neuron disease randomized trialDouble blindDouble-Blind MethodDrug TherapyInternal medicinemedicineHumansAgedMED/26 - NEUROLOGIAbusiness.industryDisease progressionmedicine.diseaseAcetyl-L-carnitineSurgeryQuality of LifeAcetylcarnitine; Adult; Aged; Amyotrophic Lateral Sclerosis; Disease Progression; Double-Blind Method; Drug Therapy Combination; Excitatory Amino Acid Antagonists; Female; Humans; Male; Middle Aged; Nootropic Agents; Pilot Projects; Quality of Life; Riluzole; Treatment Outcome; Vital CapacityNeurology (clinical)businessExcitatory Amino Acid Antagonists
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Effects of Chitosan on Plasma Lipids and Lipoproteins

2014

Chitosan can favorably modulate plasma lipids, but the available data are not conclusive. We evaluated the effect of chitosan on plasma lipids and lipoproteins in 28 patients with plasma triglyceride levels >150 mg/dL (mean age: 63 ± 12 years), not taking other lipid-lowering agents. All patients received a chitosan derived from fungal mycelium (Xantonet, Bromatech, Italy) at a fixed dose of 125 mg/d in addition to their current medications for 4 months. Polyacrylamide gel electrophoresis was used to measure low-density lipoprotein (LDL) subclasses. After treatment, total cholesterol reduced by 8%, LDL cholesterol by 2%, and triglycerides by 19%, with a concomitant 14% increase in high-…

Malechitosan; lipids; lipoproteins; therapymedicine.medical_specialtyFuture studiesPilot ProjectsFixed doseBody Mass IndexChitosanchemistry.chemical_compoundlipidInternal medicinePlasma lipidsmedicineHumansProspective StudiesPolyacrylamide gel electrophoresisTriglyceridesHypertriglyceridemiaLdl cholesteroltherapybusiness.industryAnticholesteremic AgentslipoproteinMiddle AgedLipoproteins LDLCholesterolEndocrinologychemistryConcomitantFemalelipids (amino acids peptides and proteins)Waist CircumferencechitosanLipoproteins HDLCardiology and Cardiovascular MedicinebusinessLipoproteinAngiology
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Reliability, validity and feasibility of nail ultrasonography in psoriatic arthritis

2016

International audience; Objective: To determine the feasibility, reliability and validity of nails ultrasonography in psoriatic arthritis as an outcome measure.Methods: Pilot prospective single-centre study of eight ultrasonography parameters in B mode and power Doppler concerning the distal interphalangeal (DIP) joint, the matrix, the bed and nail plate. Intraobserver and inter-observer reliability was evaluated for the seven quantitative parameters (ICC and kappa). Correlations between ultrasonography and clinical variables were searched to assess external validity. Feasibility was assessed by the time to carry out the examination and the percentage of missing data.Results: Twenty-seven p…

MalecognitionbehaviorsPilot ProjectsNailperceptionfrontotemporal dementia030207 dermatology & venereal diseases0302 clinical medicineProspective StudiesUltrasonographyObserver VariationmechanismsSynovitismedicine.diagnostic_testFeasibilitytoolMiddle AgedNail plateReliability3. Good healthmedicine.anatomical_structure[SDV.MHEP.RSOA]Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal systemPsoriatic arthritisNail (anatomy)Femalemovementmedicine.symptomAdultmedicine.medical_specialtyPhysical examinationValidity[ SDV.MHEP.RSOA ] Life Sciences [q-bio]/Human health and pathology/Rhumatology and musculoskeletal systemExternal validity03 medical and health sciencesPsoriatic arthritisRheumatologyvisuomotor integrationFinger JointSynovitismedicineHumansAged030203 arthritis & rheumatologybusiness.industryArthritis PsoriaticEnthesitisReproducibility of ResultsapraxiaUltrasonography Dopplermedicine.diseaseSurgeryNailsFeasibility StudiesbusinessNuclear medicineKappaJoint Bone Spine
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Associations Between Physical and Executive Functions Among Community-Dwelling Older Men and Women

2022

Walking is a complex task requiring the interplay of neuromuscular, sensory, and cognitive functions. Owing to the age-related decline in cognitive and physical functions, walking may be compromised in older adults, for cognitive functions, especially poor performance in executive functions, is associated with slow walking speed. Hence, the aim of this study was to investigate the associations between different subdomains of executive functions and physical functions and whether the associations found differ between men and women. Multiple linear regression analysis was performed on data collected from 314 community-dwelling older adults who did not meet physical activity guidelines but had…

Malecognitionsex differenceskognitiomedicine.medical_specialtytoiminnanohjaus (psykologia)Physical fitnesssukupuolierotfyysinen toimintakykyPhysical Therapy Sports Therapy and RehabilitationSensory systemWalkinggaitTask (project management)Executive FunctionCognitionPhysical medicine and rehabilitationdual-task costtoimintakykymedicineHumansGaitAgedbusiness.industryRehabilitationCognitionExecutive functionsGait3142 Public health care science environmental and occupational healthWalking Speedkävely3141 Health care sciencePreferred walking speedFemaleMultiple linear regression analysisIndependent LivingGeriatrics and GerontologybusinessPsychologyGerontologyikääntyneet
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Association Between Chromosome 9p21 Variants and the Ankle-Brachial Index Identified by a Meta-Analysis of 21 Genome-Wide Association Studies

2012

Background— Genetic determinants of peripheral arterial disease (PAD) remain largely unknown. To identify genetic variants associated with the ankle-brachial index (ABI), a noninvasive measure of PAD, we conducted a meta-analysis of genome-wide association study data from 21 population-based cohorts. Methods and Results— Continuous ABI and PAD (ABI ≤0.9) phenotypes adjusted for age and sex were examined. Each study conducted genotyping and imputed data to the ≈2.5 million single nucleotide polymorphisms (SNPs) in HapMap. Linear and logistic regression models were used to test each SNP for association with ABI and PAD using additive genetic models. Study-specific data were combined using fi…

Malegenetic associationGenome-wide association studyAetiology screening and detection [ONCOL 5]030204 cardiovascular system & hematologyBioinformaticsCohort Studies0302 clinical medicineRisk FactorsGenotypeCARDIOVASCULAR RISK-FACTORSInternational HapMap ProjectGenetics (clinical)POPULATIONGeneticsAged 80 and overPeripheral Vascular Diseases0303 health scienceseducation.field_of_studyAge FactorsMiddle AgedPhenotypeperipheral vascular diseaseMeta-analysiscardiovascular system/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingCORONARY-ARTERY-DISEASEFemaleCardiology and Cardiovascular MedicineChromosomes Human Pair 9AdultSUSCEPTIBILITY LOCIGenotypePopulationHapMap ProjectBiologyPolymorphism Single NucleotideArticleMolecular epidemiology [NCEBP 1]03 medical and health sciencesSex FactorsSDG 3 - Good Health and Well-beingGeneticscohort studyHumansAnkle Brachial Indexcardiovascular diseasesAlleleeducationHealth aging / healthy living Cardiovascular diseases [IGMD 5]AllelesMolecular epidemiology Aetiology screening and detection [NCEBP 1]030304 developmental biologyGenetic associationAgedCyclin-Dependent Kinase Inhibitor p15ABDOMINAL AORTIC-ANEURYSMcohort study ; genetic association ; genome-wide association study ; meta-analysis ; peripheral vascular diseasegenome-wide association studyMORTALITYChromosomeGENEmeta-analysisbody regionsLogistic ModelsMYOCARDIAL-INFARCTIONATHEROSCLEROSISSEQUENCE VARIANThuman activities
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Auditory Short-Term Memory Activation during Score Reading

2013

Performing music on the basis of reading a score requires reading ahead of what is being played in order to anticipate the necessary actions to produce the notes. Score reading thus not only involves the decoding of a visual score and the comparison to the auditory feedback, but also short-term storage of the musical information due to the delay of the auditory feedback during reading ahead. This study investigates the mechanisms of encoding of musical information in short-term memory during such a complicated procedure. There were three parts in this study. First, professional musicians participated in an electroencephalographic (EEG) experiment to study the slow wave potentials during a t…

Malegenetic structuresVisual SystemAudiologyElectroencephalographySocial and Behavioral SciencesTask (project management)memory0302 clinical medicinepartituuritReading (process)scorePsychologyta515media_commonClinical NeurophysiologyAuditory feedbackMultidisciplinarymedicine.diagnostic_testMusic psychologyQ05 social sciencesRElectroencephalographyExperimental PsychologyMiddle AgedhumanitiesSensory SystemsInterval (music)aktivointiMemory Short-TermAuditory SystemAuditory PerceptionEvoked Potentials AuditoryMedicineSensory PerceptionResearch ArticleAuditory perceptionAdultmedicine.medical_specialty515 PsychologySciencemedia_common.quotation_subjectShort-term memoryBiology050105 experimental psychology03 medical and health sciencesYoung AdultDiagnostic MedicineMemoryNeuropsychologymedicineReaction TimeLearningHumansmusic0501 psychology and cognitive sciencesBiologyBehaviorscore readingCognitive PsychologymuistiReadingRecall030217 neurology & neurosurgeryMusicNeurosciencePLoS ONE
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