Search results for "Propionic acid"

showing 10 items of 21 documents

Nuclear Translocation of Nuclear Transcription Factor-κB by α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Receptors Leads to Transcription of …

2003

We describe a new molecular mechanism of cell death by excitotoxicity mediated through nuclear transcription factor κB (NFκB) in rat embryonic cultures of dopaminergic neurons. Treatment of mesencephalic cultures with α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) resulted in a number of changes that occurred selectively in dopaminergic neurons, including persistent elevation in intracellular Ca2+ monitored with Fura-2, and a significant increase in intramitochondrial oxidation of dihydrorhodamine 123, probably associated with transient increase of mitochondrial permeability, cytochrome c release, nuclear translocation of NFκB, and transcriptional activation of the oncogenep53.…

Programmed cell deathCell Membrane PermeabilityTime FactorsCIENCIAS MÉDICAS Y DE LA SALUDTranscription GeneticNeuriteActive Transport Cell NucleusInmunologíaExcitotoxicitymedicine.disease_causeCELL DEATHReceptors DopamineRats Sprague-DawleymedicineAnimalsReceptors AMPAalpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic AcidTranscription factorPARKINSON DISEASECaspaseNeuronsPharmacologyCell DeathNUCLEAR TRANSCRIPTIONbiologyDopaminergicNF-kappa BNFKB1Molecular biologyMitochondriaRatsCell biologyMedicina Básicabiology.proteinMolecular MedicineCalciumFemaleTumor Suppressor Protein p53Signal transductionMolecular Pharmacology
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Systemic PaO2 oscillations cause mild brain injury in a pig model

2016

OBJECTIVE: Systemic PaO2 oscillations occur during cyclic recruitment and derecruitment of atelectasis in acute respiratory failure and might harm brain tissue integrity. DESIGN: Controlled animal study. SETTING: University research laboratory. SUBJECTS: Adult anesthetized pigs. INTERVENTIONS: Pigs were randomized to a control group (anesthesia and extracorporeal circulation for 20 hr with constant PaO2, n = 10) or an oscillation group (anesthesia and extracorporeal circulation for 20 hr with artificial PaO2 oscillations [3 cycles min⁻¹], n = 10). Five additional animals served as native group (n = 5). MEASUREMENTS AND MAIN RESULTS: Outcome following exposure to artificial PaO2 oscillations…

Pulmonary Atelectasismedicine.medical_specialtySwinemedicine.medical_treatment10208 Institute of NeuropathologyHippocampusInflammation610 Medicine & healthHippocampal formationReal-Time Polymerase Chain ReactionCritical Care and Intensive Care Medicinegamma-Aminobutyric acidRNA ComplementaryRandom Allocation03 medical and health sciencesExtracorporeal Membrane Oxygenation0302 clinical medicine030202 anesthesiologyNeurotransmitter receptorInternal medicinemedicineExtracorporeal membrane oxygenationAnimalsReceptoralpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acidgamma-Aminobutyric AcidRespiratory Distress Syndromebusiness.industryExtracorporeal circulationRespiration Artificialrespiratory tract diseasesEndocrinologyBrain Injuries570 Life sciences; biologyBlood Gas AnalysisInflammation Mediatorsmedicine.symptombusiness2706 Critical Care and Intensive Care Medicine030217 neurology & neurosurgerymedicine.drug
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CCDC 250249: Experimental Crystal Structure Determination

2005

Related Article: A.Volonterio, C.Ramirez de Arellano, M.Zanda|2005|J.Org.Chem.|70|2161|doi:10.1021/jo0480848

Space GroupCrystallography2-(13-Di-t-butyl-25-dioxoimidazolidin-4-yl)-333-trifluoropropionic acid ethyl esterCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 204503: Experimental Crystal Structure Determination

2004

Related Article: A.Volonterio, S.Bellosta, F.Bravin, M.C.Bellucci, L.Bruche, G.Colombo, L.Malpezzi, S.Mazzini, S.V.Meille, M.Meli, C.R.de Arellano, M.Zanda|2003|Chem.-Eur.J.|9|4510|doi:10.1002/chem.200304881

Space GroupCrystallographyCrystal System3-Phenyl-(2S)-(444-trifluoro-(3R)-((1S)-methoxycarbonylethylamino)butyrylamino)propionic acid benzyl esterCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 204501: Experimental Crystal Structure Determination

2004

Related Article: A.Volonterio, S.Bellosta, F.Bravin, M.C.Bellucci, L.Bruche, G.Colombo, L.Malpezzi, S.Mazzini, S.V.Meille, M.Meli, C.R.de Arellano, M.Zanda|2003|Chem.-Eur.J.|9|4510|doi:10.1002/chem.200304881

Space GroupCrystallographyCrystal SystemCrystal Structure2S-(3-((4S)-Benzyl-2-oxo-oxazolidin-3-yl)-3-oxo-(1S)-trifluoromethyl-propylamino)propionic acid methyl esterCell ParametersExperimental 3D Coordinates
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CCDC 229785: Experimental Crystal Structure Determination

2004

Related Article: B.Kranke, D.Hebrault, M.Schultz-Kukula, H.Kunz|2004|Synlett|2004|671|doi:10.1055/s-2004-817775

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters22-Dimethylpropionic acid 45-bis(22-dimethylpropionyloxy)-2-(4-oxo-2-propyl-34-dihydro-2H-pyridin-1-yl)-tetrahydropyran-3-yl esterExperimental 3D Coordinates
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CCDC 641724: Experimental Crystal Structure Determination

2007

Related Article: J.B.Kyziol, E.M.Nowakowska, J.Zaleski|2007|Acta Crystallogr.,Sect.E:Struct.Rep.Online|63|o2834|doi:10.1107/S1600536807021332

Space GroupCrystallographybeta-(369-Trimethyl-9-xanthenyl)propionic acidCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 177330: Experimental Crystal Structure Determination

2002

Related Article: Y.Akhriff, J.Server-Carrio, A.Sancho, J.Garcia-Lozano, E.Escriva, L.Soto|2001|Inorg.Chem.|40|6832|doi:10.1021/ic0106571

Space GroupCrystallographycatena-((mu~2~-33-bis(2-Imidazolyl)propionato-NN'O)-(33-bis(2-imidazolyl)propionic acid-NN')-copper(ii) hemikis(squarate) dihydrate)Crystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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Thermal and X-ray powder diffraction studies of aliphatic polyester dendrimers

2004

The syntheses and thermal and X-ray powder diffraction analyses of three sets of aliphatic polyester dendrimers based on 2,2-bis(hydroxymethyl)propionic acid as a repeating unit and 2,2-dimethyl-1,3-propanediol, 1,5-pentanediol, and 1,1,1-tris(hydroxymethyl)ethane as core molecules are reported. These dendritic polyesters were prepared in high yields with the divergent method. The thermal properties of these biodendrimers were evaluated with thermogravimetric analysis and differential scanning calorimetry. The thermal decomposition of the compounds occurred around 250 °C for the hydroxyl-ended dendrimers and around 150 °C for the acetonide-protected dendrimers. In addition, the crystallinit…

Thermogravimetric analysisDendrimersPolymers and PlasticsChemistryThermogravimetric analysis (TGA)2-bis(hydroxymethyl)propionic acid (bis-MPA)Organic ChemistryThermal decomposition2Differential scanning calorimetry (DSC)PolyesterCrystallinitychemistry.chemical_compoundDifferential scanning calorimetryDendrimerPolymer chemistryMaterials Chemistry22-bis(hydroxymethyl)propionic acid (bis-MPA)Physical chemistryAliphatic polyestersHydroxymethylPowder diffraction
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Leaching of glyphosate and AMPA under two soil management practices in Burgundy vineyards (Vosne-Romanée, 21-France)

2005

Some drinking water reservoirs under the vineyards of Burgundy are contaminated with herbicides. Thus the effectiveness of alternative soil management practices, such as grass cover, for reducing the leaching of glyphosate and its metabolite, AMPA, through soils was studied. The leaching of both molecules was studied in structured soil columns under outdoor conditions for 1 year. The soil was managed under two vineyard soil practices: a chemically treated bare calcosol, and a vegetated calcosol. After 680 mm of rainfall, the vegetated calcosol leachates contained lower amounts of glyphosate and AMPA (0.02% and 0.03%, respectively) than the bare calcosol leachates (0.06% and 0.15%, respectiv…

[SDE] Environmental SciencesHealth Toxicology and Mutagenesis010501 environmental sciencesToxicology01 natural sciences[ SDE ] Environmental SciencesSoil managementchemistry.chemical_compoundSoilAMPASoil PollutantsVitisLeaching (agriculture)Water pollutionComputingMilieux_MISCELLANEOUS2. Zero hungerAgriculture04 agricultural and veterinary sciencesGeneral MedicinePollutionSoil contaminationSTRUCTURED SOIL COLUMN6. Clean waterGlyphosate[SDE]Environmental SciencesFrancePorosityEnvironmental MonitoringGRASS COVERGlycineGLYPHOSATEPoaceaecomplex mixturesWater MovementsHumansalpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid0105 earth and related environmental sciencesCambisolHerbicides15. Life on land[SDE.ES]Environmental Sciences/Environmental and SocietyTRANSPORTAgronomychemistrySoil water040103 agronomy & agriculture0401 agriculture forestry and fisheriesEnvironmental scienceGroundwaterWater Pollutants Chemical
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