Search results for "Propylene oxide"

showing 10 items of 50 documents

Spectroscopic study of the aluminium/lumogallion system in the presence of non-ionic surfactants

1987

Abstract The effects of different non-ionic ethylene oxide condensate surfactants on the fluorescence and the molecular absorption of the aluminium/lumogallion system are reported. Ethylene oxide condensates with fatty alcohols give higher micellar enhancement factors than tert-octylphenols or nonylphenols; ethylene oxide/propylene oxide copolymers provide only a 50% increase in the fluorescence of the complex. The aluminium/lumogallion seems to form mixed micelles with the fatty alcohol condensates; the strong complex/micelle interaction provides increased absorbance of the complex at 500 nm and higher fluorescence enhancement, allowing the detection of 0.11 μg l −1 aluminium.

Ethylene oxideChemistryInorganic chemistrychemistry.chemical_elementFatty alcoholBiochemistryMicelleFluorescenceAnalytical ChemistryAbsorbancechemistry.chemical_compoundAluminiumCopolymerEnvironmental ChemistryPropylene oxideSpectroscopyAnalytica Chimica Acta
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Quantitative description of temperature induced self-aggregation thermograms determined by differential scanning calorimetry

2012

A novel thermodynamic approach for the description of differential scanning calorimetry (DSC) experiments on self-aggregating systems is derived and presented. The method is based on a mass action model where temperature dependence of aggregation numbers is considered. The validity of the model was confirmed by describing the aggregation behavior of poly(ethylene oxide)-poly(propylene oxide) block copolymers, which are well-known to exhibit a strong temperature dependence. The quantitative description of the thermograms could be performed without any discrepancy between calorimetric and van 't Hoff enthalpies, and moreover, the aggregation numbers obtained from the best fit of the DSC exper…

Ethylene oxideSelf aggregationThermodynamicsSurfaces and InterfacesCondensed Matter PhysicsTemperature inducedLight scatteringchemistry.chemical_compoundDifferential scanning calorimetrychemistryDSC Micelle copolymer calorimetryElectrochemistryCopolymerPhysical chemistryGeneral Materials SciencePropylene oxideAction modelSpectroscopySettore CHIM/02 - Chimica Fisica
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Glycidyl Tosylate: Polymerization of a “Non‐Polymerizable” Monomer permits Universal Post‐Functionalization of Polyethers

2019

Abstract Glycidyl tosylate appears to be a non‐polymerizable epoxide when nucleophilic initiators are used because of the excellent leaving group properties of the tosylate. However, using the monomer‐activated mechanism, this unusual monomer can be copolymerized with ethylene oxide (EO) and propylene oxide (PO), respectively, yielding copolymers with 7–25 % incorporated tosylate‐moieties. The microstructure of the copolymers was investigated via in situ 1H NMR spectroscopy, and the reactivity ratios of the copolymerizations have been determined. Quantitative nucleophilic substitution of the tosylate‐moiety is demonstrated for several examples. This new structure provides access to a librar…

Ethylene oxidering-opening polymerization010405 organic chemistryCommunicationLeaving groupEpoxideGeneral Chemistry010402 general chemistry01 natural sciencesRing-opening polymerizationCommunicationsCatalysis0104 chemical scienceschemistry.chemical_compoundMonomerchemistryPolymerizationpolyetherPolymer chemistryCopolymerNucleophilic substitutionRing‐Opening Polymerizationfunctionalizationpoly(ethylene oxide)poly(propylene oxide)Angewandte Chemie International Edition
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In vitro evaluation of poloxamer in situ forming gels for bedaquiline fumarate salt and pharmacokinetics following intramuscular injection in rats

2019

Graphical abstract

In situPO Propylene oxideIV IntravenousP338 Poloxamer 338lcsh:RS1-441Pharmaceutical Sciencechemistry.chemical_compoundn Sample sizeSD Standard deviationIM Intramuscularchemistry.chemical_classificationC0 Analyte plasma concentration at time zeroDoE Design of experimentsUV UltravioletPharmacology. TherapyK2.EDTA Potassium ethylenediaminetetraacetic acidLC–MS/MS Liquid chromatography-tandem mass spectrometryH&E Hematoxylin and eosintmax Sampling time to reach the maximum observed analyte plasma concentrationIn situ forming gelsCMC Critical micellar concentrationCmax Maximum observed analyte plasma concentrationIntramuscular injectionDN Dose normalizedGPT Gel point temperaturePLGA Poly-(DL-lactic-co-glycolic acid)TFA Trifluoroacetic acidCAN AcetonitrileATP Adenosine 5′ triphosphateSalt (chemistry)Polyethylene glycolPoloxamerArticlelcsh:Pharmacy and materia medicaPharmacokineticsIn vivoUHPLC Ultra-high performance liquid chromatographyPharmacokineticsAUClast Area under the analyte concentration versus time curve from time zero to the time of the last measurable (non-below quantification level) concentrationEO Ethylene oxideNMP N-methyl-2-pyrrolidoneComputingMethodologies_COMPUTERGRAPHICSAUC∞ Area under the analyte concentration vs time curve from time zero to infinite timeP407 Poloxamer 407In vitro releasePoloxamerCMT Critical micellar temperatureGel erosionIn vitrot1/2 Apparent terminal elimination half-lifechemistryMDR-TB Multi-drug resistant tuberculosisAUC80h Area under the analyte concentration versus time curve from time zero to 80 htlast Sampling time until the last measurable (non-below quantification level) analyte plasma concentrationMRM Multiple reaction monitoringNuclear chemistrySustained releaseInternational Journal of Pharmaceutics: X
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Binding of Short Alkyl Chain Surfactants to the (Ethylene oxide)13−(Propylene oxide)30−(Ethylene oxide)13and (Ethylene oxide)75−(Propylene oxide)30−(…

2002

The enthalpy of transfer (ΔHt) of neutral copolymers, at a fixed and low concentration ca. 10-3 mol kg-1, from water to the aqueous surfactant solutions as a function of the surfactant concentration (fSmS) was determined at 25 °C. The surfactants studied are sodium octanoate, sodium decanoate, N-octylpyridinium chloride (OPC), and N,N-dimethyloctylamine-N-oxide (ODAO). The copolymers are (ethylene oxide)13−(propylene oxide)30−(ethylene oxide)13 (L64) and (ethylene oxide)75−(propylene oxide)30−(ethylene oxide)75 (F68). The two copolymers show different hydrophilic−hydrophobic ratios, the larger being for F68. As a general feature, the shape of the ΔHt vs fSmS curve depends on the nature of t…

Isothermal microcalorimetrychemistry.chemical_classificationAqueous solutionPolymers and PlasticsEthylene oxideOrganic ChemistryInorganic chemistryChlorideInorganic Chemistrychemistry.chemical_compoundchemistryPulmonary surfactantMaterials ChemistrymedicineCopolymerPropylene oxideAlkylmedicine.drugMacromolecules
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Small Angle Neutron Scattering, X-ray Diffraction, Differential Scanning Calorimetry, and Thermogravimetry Studies to Characterize the Properties of …

2009

Nanocomposites based on laponite RD and (ethylene oxide)98(propylene oxide)67(ethylene oxide)98 (F127)triblock copolymer or poly(ethylene) glycol 2000 (PEG2000) were prepared by using the melting method. Small-angle neutron scattering and the X-ray diffraction experiments provided insights into the organization of the laponite RD dispersed in the macromolecular matrix over a wide length scale. SANS data analysis by means of a fractal law evidenced the formation of clusters of laponite RD at long correlation distance. The single laponite RD particles and the lamellar structure of F127 were described in the shorter length scale. Finally, the crystalline structure of the macromolecule was obse…

Length scaleTGAMaterials scienceEthylene oxidenanocompositepoly(ethylene oxide)poly(propylene oxide)poly(ethylene oxide)SANSXRDAnalytical chemistrypoly(ethylene)glycol 2000laponite RDNeutron scatteringSmall-angle neutron scatteringSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsDSCThermogravimetrychemistry.chemical_compoundGeneral EnergyDifferential scanning calorimetrychemistryX-ray crystallographyLamellar structurePhysical and Theoretical Chemistry
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Pluronic nanoparticles as anti-oxidant carriers for polymers

2016

Abstract The immobilization of anti-oxidant stabilizers for polymers, particularly naturally occurring systems, can be considered a valuable route for preventing their migration, volatilization, thermo-degradation and decomposition at typical high processing temperatures, as well as for enhance their solubility in polymers. In this work, an innovative approach for the immobilization of naturally occurring stabilizer, through the encapsulation in copolymer nanoparticles, is proposed. Pluronic nanoparticles (PNPs), based on PEO-PPO-PEO, (PEO: poly (ethylene oxide); PPO: poly(propylene oxide)), without and with quercetin, Q, have been successfully formulated and the critical micellar condition…

Materials Chemistry2506 Metals and AlloysAnti-oxidant carrierMaterials sciencePEO-PPO-PEO nanoparticlePolymers and PlasticsNanoparticle02 engineering and technologyCondensed Matter Physic010402 general chemistry01 natural scienceschemistry.chemical_compoundDynamic light scatteringPolymer chemistryMaterials ChemistryPhoto-oxidationMechanics of MaterialPropylene oxideSolubilitychemistry.chemical_classificationPolymers and PlasticEthylene oxideAnti-oxidant carrier; PEO-PPO-PEO nanoparticles; Photo-oxidation; Condensed Matter Physics; Mechanics of Materials; Polymers and Plastics; Materials Chemistry; 2506; Metals and Alloystechnology industry and agricultureMetals and AlloysPolymerPoloxamer021001 nanoscience & nanotechnologyCondensed Matter Physics0104 chemical scienceschemistryChemical engineeringMechanics of MaterialsPEO-PPO-PEO nanoparticles25060210 nano-technologyEthylene glycol
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Polymeric micelles as a new generation of anti-oxidant carriers

2017

A promising strategy to immobilize a natural stabilizer in polymeric films is presented. Par-Ticularly, nevadensin (N, a natural basil flavonoid) molecules have been encapsulated in Pluronic F-127 micelles [F127, a triblock copolymer poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide)] and the obtained nanoparticles have been introduced in poly(ethylene glycol), PEG [otherwise known as poly(ethylene oxide), PEO]. In order to verify the effectiveness of the micelles as anti-oxidant carriers, PEG-based films have been subjected to artificial weathering. The encapsulation of anti-oxidant molecules allows the enhancement of N solubility in PEG, leading to advanced materials with enh…

Materials Chemistry2506 Metals and AlloysAnti-oxidant carrierPhoto-oxidative stabilityPolymers and PlasticsGeneral Chemical EngineeringPoly(ethylene oxide)Nanoparticlemacromolecular substances02 engineering and technology01 natural sciencesMicellechemistry.chemical_compoundAnti-oxidant carriers; Photo-oxidative stability; Poly(ethylene oxide); Polymeric micelles; Chemical Engineering (all); Polymers and Plastics; Materials Chemistry; 2506; Metals and AlloysPolymeric micellePEG ratioCopolymerMaterials ChemistryChemical Engineering (all)Propylene oxidePolymers and PlasticEthylene oxidetechnology industry and agricultureMetals and AlloysPoloxamer021001 nanoscience & nanotechnology010406 physical chemistry0104 chemical scienceschemistryChemical engineeringPolymeric micelles25060210 nano-technologyAnti-oxidant carriersEthylene glycol
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The poly(propylene oxide-co-ethylene oxide) gradient is controlled by the polymerization method: determination of reactivity ratios by direct compari…

2019

An investigation of the highly relevant copolymerization of ethylene oxide (EO) and propylene oxide (PO) by in situ1H NMR spectroscopy shows striking differences in the copolymerization kinetics, depending on the polymerization method. Examination of the EO/PO copolymerization kinetics using iBu3Al for the monomer-activated anionic ring opening polymerization (AROP) confirmed a strong monomer gradient of the microstructure (rEO = 6.4, rPO = 0.16) in contrast to the known weak gradient in the conventional AROP (rEO = 2.8, rPO = 0.25). The first study via in situ1H-NMR kinetics of the copolymerization of PO and EO under heterogeneous double metal cyanide (DMC) catalysis, a method that produce…

Materials sciencePolymers and PlasticsEthylene oxideOrganic ChemistryKineticsBioengineering02 engineering and technology010402 general chemistry021001 nanoscience & nanotechnology01 natural sciencesBiochemistryRing-opening polymerization0104 chemical scienceschemistry.chemical_compoundMonomerchemistryPolymerizationCopolymerPhysical chemistryReactivity (chemistry)Propylene oxide0210 nano-technologyPolymer Chemistry
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Thioether-Bearing Hyperbranched Polyether Polyols with Methionine-Like Side-Chains: A Versatile Platform for Orthogonal Functionalization

2016

The synthesis of thioether-bearing hyperbranched polyether polyols based on an AB/AB2 type copolymerization (cyclic latent monomers) is introduced. The polymers are prepared by anionic ring-opening multibranching copolymerization of glycidol and 2-(methylthio)ethyl glycidyl ether (MTEGE), which is conveniently accessible in a single etherification step. Slow monomer addition provides control over molecular weights. Moderate dispersities (Đ = 1.48–1.85) are obtained, given the hyperbranched structure. In situ 1H NMR copolymerization kinetics reveal reactivity ratios of rG = 3.7 and rMTEGE = 0.27. Using slow monomer addition, copolymer composition can be systematically varied, allowing for th…

Materials sciencePolymers and PlasticsPolymersAllyl glycidyl ether02 engineering and technology010402 general chemistryBranching (polymer chemistry)01 natural sciencesPolymerizationchemistry.chemical_compoundMethionineThioetherPolymer chemistryMaterials ChemistryCopolymerOrganic chemistrySulfhydryl CompoundsPropylene oxideMolecular StructureOrganic ChemistryTemperatureGlycidol021001 nanoscience & nanotechnologyIsocyanate0104 chemical sciencesMonomerchemistry0210 nano-technologyEthersMacromolecular Rapid Communications
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