Search results for "Prostate Cancer"

showing 10 items of 413 documents

Evaluation of prostate segmentation algorithms for MRI: The PROMISE12 challenge

2014

Contains fulltext : 137969.pdf (Publisher’s version ) (Open Access) Prostate MRI image segmentation has been an area of intense research due to the increased use of MRI as a modality for the clinical workup of prostate cancer. Segmentation is useful for various tasks, e.g. to accurately localize prostate boundaries for radiotherapy or to initialize multi-modal registration algorithms. In the past, it has been difficult for research groups to evaluate prostate segmentation algorithms on multi-center, multi-vendor and multi-protocol data. Especially because we are dealing with MR images, image appearance, resolution and the presence of artifacts are affected by differences in scanners and/or …

MaleScannerObserver (quantum physics)Computer scienceHealth InformaticsSensitivity and SpecificityArticleProstate cancerSegmentationImaging Three-DimensionalRobustness (computer science)Image Interpretation Computer-AssistedmedicineHumansRadiology Nuclear Medicine and imagingSegmentationChallengeProtocol (science)Modality (human–computer interaction)Radiological and Ultrasound TechnologyProstateProstatic NeoplasmsReproducibility of ResultsReference Standardsmedicine.diseaseImage EnhancementComputer Graphics and Computer-Aided DesignMagnetic Resonance ImagingActive appearance modelUrological cancers Radboud Institute for Health Sciences [Radboudumc 15]Computer Vision and Pattern RecognitionArtifactsAlgorithmAlgorithmsRare cancers Radboud Institute for Health Sciences [Radboudumc 9]MRI
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Evaluation of Deep Neural Networks for Semantic Segmentation of Prostate in T2W MRI

2020

In this paper, we present an evaluation of four encoder&ndash

MaleSimilarity (geometry)Computer scienceSegNet02 engineering and technologylcsh:Chemical technologyBiochemistryArticleencoder–decoder030218 nuclear medicine & medical imagingAnalytical Chemistry03 medical and health sciencesProstate cancer0302 clinical medicineProstateImage Processing Computer-Assisted0202 electrical engineering electronic engineering information engineeringmedicineHumanslcsh:TP1-1185SegmentationElectrical and Electronic EngineeringInstrumentationmedicine.diagnostic_testPixelbusiness.industryProstateCNNsPattern recognitionMagnetic resonance imagingFCNmedicine.diseaseMagnetic Resonance ImagingU-NetAtomic and Molecular Physics and OpticsSemanticsIntensity normalizationmedicine.anatomical_structureDeepLabV3+Deep neural networks020201 artificial intelligence & image processingNeural Networks ComputerArtificial intelligencebusinessDNNSensors
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Cryopreservation of prostate cancer tissue during routine processing of fresh unfixed prostatectomy specimen: demonstration and validation of a new t…

2008

BACKGROUND Most molecular techniques currently require fresh frozen tumor tissue, which in the case of prostatectomy specimen is a challenge to obtain for a variety of intrinsic reasons. Prostate cancers are usually located in the organ periphery and hence meticulous attention has to be paid to the relation between the tumor and the surgical margin. In this article we describe a new technique that allows to obtain fresh frozen tumor material in rather large quantities and without jeopardizing diagnostic accuracy. METHOD An inner triangle, representing roughly 50% of the entire prostate tissue, is removed from native prostatectomy specimen and cryopreserved, leaving the periphery of the orga…

MaleSurgical marginmedicine.medical_specialtyUrologymedicine.medical_treatmentCryopreservationProstate cancerProstatemedicineCarcinomaHumansCryopreservationProstatectomybusiness.industryProstatectomyProstatic NeoplasmsReproducibility of ResultsHistologymedicine.diseaseSurgerymedicine.anatomical_structureOncologyTissue bankRadiologyArtifactsbusinessThe Prostate
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Towards the potential use of (1)H NMR spectroscopy in urine samples for prostate cancer detection

2014

A simple method based in multivariate analysis of 1H NMR spectra profiles of urine samples can be used to detect patients with prostate cancer.

MaleUrine samples1h nmr spectroscopyMagnetic Resonance SpectroscopyPerformanceAnalytical chemistryUrineUrinalysisBiochemistryAnalytical ChemistryProstate cancerMetabolomicsValidationElectrochemistrymedicineSecretionsHumansEnvironmental ChemistryMetabolomicsPROYECTOS DE INGENIERIASpectroscopyChromatographyProstate cancerChemistryfungiQUIMICA INORGANICAProstateProstatic Neoplasmsfood and beverages1H NMRmedicine.diseaseTissuesMultivariate analysisProton NMR
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AR-V7 Protein Expression in Circulating Tumour Cells Is Not Predictive of Treatment Response in mCRPC

2019

<b><i>Introduction:</i></b> Androgen receptor variant 7 (AR-V7) plays an important role in the progression of castration-resistant prostate cancer (CRPC) and has shown potential as a predictive biomarker in circulating tumour cells (CTCs) isolated from the bloodstream in terms of a liquid biopsy. Studies have shown that AR-V7 is a potential surrogate for selecting drug classes for systemic treatment by detecting nuclear AR-V7 by immunofluorescence or measuring AR-V7 messenger RNA by quantitative PCR. Here, we assessed the predictive value of AR-V7 detected by classical immunohistochemistry (IHC) for treatment response. <b><i>Methods:</i></b> C…

MaleUrology030232 urology & nephrologyAntineoplastic AgentsDocetaxel03 medical and health scienceschemistry.chemical_compoundProstate cancer0302 clinical medicineCell Line TumormedicineHumansEnzalutamideProspective StudiesLiquid biopsyAgedAged 80 and overbusiness.industryAndrogen AntagonistsNeoplastic Cells CirculatingPrognosismedicine.diseaseAndrogen receptorProstatic Neoplasms Castration-ResistantTreatment OutcomeDocetaxelchemistryReceptors AndrogenCabazitaxel030220 oncology & carcinogenesisCancer researchBiomarker (medicine)ImmunohistochemistryTaxoidsbusinessmedicine.drugUrologia Internationalis
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The Impact of 68Ga-PSMA PET/CT and PET/MRI on the Management of Prostate Cancer.

2018

Prostate-specific membrane antigen (PSMA) is a transmembrane protein with significantly increased expression in the cells and metastases of prostate carcinoma (CaP). PSMA-expression correlates with higher serum levels of prostate-specific antigen (PSA) and a higher Gleason score (GS). This finding has led to the development of novel imaging modalities such as 68Ga-/18F-labeled PSMA positron emission tomography/computed tomography (PET/CT) and positron emission tomography/magnetic resonance imaging (PET/MRI). This article reviews the literature pertaining to various new imaging technologies for the management of CaP. PSMA positron emission tomography/computed tomography appears to be an exce…

MaleUrology030232 urology & nephrologyComputed tomographyGallium Radioisotopesurologic and male genital diseasesMultimodal ImagingManagement of prostate cancer03 medical and health sciences0302 clinical medicinePositron Emission Tomography Computed TomographymedicineOrganometallic CompoundsHumansGallium IsotopesMembrane antigenSalvage TherapyPET-CTMembrane Glycoproteinsmedicine.diagnostic_testbusiness.industry68ga psmaProstatic NeoplasmsMagnetic resonance imagingProstate carcinomaProstate-Specific AntigenMagnetic Resonance ImagingPositron emission tomography030220 oncology & carcinogenesisPositron-Emission TomographyNeoplasm Recurrence LocalRadiopharmaceuticalsbusinessNuclear medicineUrology
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Multicenter Multireader Evaluation of an Artificial Intelligence-Based Attention Mapping System for the Detection of Prostate Cancer With Multiparame…

2020

OBJECTIVE. The purpose of this study was to evaluate in a multicenter dataset the performance of an artificial intelligence (AI) detection system with attention mapping compared with multiparametric MRI (mpMRI) interpretation in the detection of prostate cancer. MATERIALS AND METHODS. MRI examinations from five institutions were included in this study and were evaluated by nine readers. In the first round, readers evaluated mpMRI studies using the Prostate Imaging Reporting and Data System version 2. After 4 weeks, images were again presented to readers along with the AI-based detection system output. Readers accepted or rejected lesions within four AI-generated attention map boxes. Additio…

MaleUrologyAdenocarcinomaSensitivity and SpecificityArticle030218 nuclear medicine & medical imaging03 medical and health sciencesProstate cancerRandom Allocation0302 clinical medicineLaparoscopicProstateArtificial IntelligenceStatistical significanceMedicineHumansAttentionRadiology Nuclear Medicine and imagingDiagnosis Computer-AssistedMultiparametric Magnetic Resonance ImagingAgedRetrospective StudiesObserver VariationProstate cancerbusiness.industryartificial intelligence; laparoscopic; MRI; multiparametric; prostate cancer; radical prostatectomy; robot-assistedSignificant differenceCancerMultiparametric MRIProstatic NeoplasmsGeneral MedicineRobot-assistedMiddle Agedmedicine.diseaseRadical prostatectomymedicine.anatomical_structure030220 oncology & carcinogenesisMapping systemMultiparametricArtificial intelligencebusinessAlgorithmsMriAJR. American journal of roentgenology
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ProstateAnalyzer: web-based medical application for the management of prostate cancer using multiparametric MR imaging

2016

Objectives: In this paper, we present ProstateAnalyzer, a new web-based medical tool for prostate cancer diagnosis. ProstateAnalyzer allows the visualization and analysis of magnetic resonance images (MRI) in a single framework. Methods: ProstateAnalyzer recovers the data from a PACS server and displays all the associated MRI images in the same framework, usually consisting of 3D T2-weighted imaging for anatomy, dynamic contrast-enhanced MRI for perfusion, diffusion-weighted imaging in the form of an apparent diffusion coefficient (ADC) map and MR Spectroscopy. ProstateAnalyzer allows annotating regions of interest in a sequence and propagates them to the others. Results: From a representat…

Male[ SDV.MHEP.UN ] Life Sciences [q-bio]/Human health and pathology/Urology and NephrologyNursing (miscellaneous)Computer scienceBiopsycomputer.software_genre[SDV.MHEP.UN]Life Sciences [q-bio]/Human health and pathology/Urology and Nephrology[ SDV.CAN ] Life Sciences [q-bio]/CancerSoftwareSegmentationHealth Information ManagementMagnetic-ResonanceProstate -- Cancer -- ImagingDiagnosisContrast-Enhanced Mrimagnetic resonance imagingSegmentationComputingMilieux_MISCELLANEOUSSpectroscopyPròstata -- Càncermedicine.diagnostic_test[ INFO.INFO-IM ] Computer Science [cs]/Medical ImagingProstate--Cancerprostate cancer3. Good healthdatabase management systemData miningImaging systems in medicinemedicine.medical_specialtyapplicationsScoring SystemHealth Informatics[SDV.CAN]Life Sciences [q-bio]/Cancer:Enginyeria dels materials [Àrees temàtiques de la UPC]Set (abstract data type)Software portabilityImatges per ressonància magnètica[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyImage Interpretation Computer-AssistedUltrasoundmedicine[INFO.INFO-IM]Computer Science [cs]/Medical ImagingWeb applicationHumansmedical informaticsMedical physicsJava appletPròstata -- Càncer -- ImatgesInternetbusiness.industryProstatic NeoplasmsMagnetic resonance imagingmagnetic resonance spectroscopyVisualizationLocalizationImagesImatgeria mèdicabusinesscomputer[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
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Time to onset of bisphosphonate-related osteonecrosis of the jaws: a multicentre retrospective cohort study

2017

Objectives: Osteonecrosis of the jaw (ONJ) is a potentially severe adverse effect of bisphosphonates (BP). Although the risk of ONJ increases with increasing duration of BP treatment, there are currently no reliable estimates of the ONJ time to onset (TTO). The objective of this study was to estimate the TTO and associated risk factors in BP-treated patients. Subjects and Methods: Retrospective analysis of data from 22 secondary care centres in seven countries relevant to 349 patients who developed BP-related ONJ between 2004 and 2012. Results: The median (95%CI) TTO was 6.0 years in patients treated with alendronate (n = 88) and 2.2 years in those treated with zoledronate (n = 218). Multiv…

MalebisphosphonateTime Factorsmedicine.medical_treatmentOsteoporosis0302 clinical medicineRisk Factors80 and overosteoporosijaw osteonecrosiAged 80 and overBone Density Conservation AgentsDiphosphonatesjaw osteonecrosisjaw osteonecrosis bisphosphonates breast cancer multiple myeloma prostate cance osteoporosisIncidenceIncidence (epidemiology)Otorhinolaryngology2734 Pathology and Forensic MedicineMiddle Agedprostate cancermultiple myeloma030220 oncology & carcinogenesisBisphosphonate-Associated Osteonecrosis of the JawFemaleAdultmedicine.medical_specialty2734Drug Administration SchedulePathology and Forensic Medicine03 medical and health sciencesbreast cancerbisphosphonates; breast cancer; jaw osteonecrosis; multiple myeloma; osteoporosis; prostate cancer; Adult; Aged; Aged 80 and over; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bone Density Conservation Agents; Cross-Sectional Studies; Diphosphonates; Drug Administration Schedule; Female; Humans; Incidence; Male; Middle Aged; Multivariate Analysis; Proportional Hazards Models; Retrospective Studies; Risk Factors; Time Factors; Otorhinolaryngology; 2734; Pathology and Forensic Medicine; Dentistry (all)Internal medicinemedicineHumansBisphosphonates; Breast cancer; Jaw osteonecrosis; Multiple myeloma; Osteoporosis; Prostate cancer; Otorhinolaryngology2734 Pathology and Forensic Medicine; Dentistry (all)prostate canceAdverse effectGeneral DentistrybisphosphonatesAgedProportional Hazards ModelsRetrospective StudiesBisphosphonate-associated osteonecrosis of the jawbusiness.industryProportional hazards modelRetrospective cohort study030206 dentistryBisphosphonatemedicine.diseaseosteoporosisSurgeryCross-Sectional StudiesOtorhinolaryngologyMultivariate AnalysisDentistry (all)businessOsteonecrosis of the jaw
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Accordance of Online Health Information on Prostate Cancer with the European Association of Urology Guidelines.

2017

<b><i>Background:</i></b> The internet is an emerging source of information for prostate cancer (PCa) patients. Since little is known about the quality of information on PCa provided online, we investigated its accordance to the latest European Association of Urology (EAU) guidelines. <b><i>Methods:</i></b> A total of 89 German web pages were included for analysis. A quality model classifying the provider of information and its expertise was introduced. Correctness of provided information was systematically compared to the EAU guidelines. <b><i>Results:</i></b> Information was provided by medical experts (41%), media (1…

Malemedicine.medical_specialtyAssociation (object-oriented programming)Urology030232 urology & nephrologyurologic and male genital diseasesAccess to Information03 medical and health sciencesProstate cancer0302 clinical medicinePatient Education as TopicGermanymedicineHumansSocieties MedicalInternetbusiness.industryInformation seekingInformation qualityProstatic Neoplasmsmedicine.diseaseInformation behaviorEuropeAccess to information030220 oncology & carcinogenesisFamily medicinePractice Guidelines as TopicThe InternetHealth informationNeoplasm Recurrence LocalbusinessUrologia internationalis
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