Search results for "Protection"
showing 10 items of 1623 documents
Control of brain temperature during experimental global ischemia in rats.
1999
Temperature control during experimental ischemia continues to be of major interest. However, if exposure of brain tissue is necessary during the experiment, regional heat loss may occur even when the core temperature is maintained. Furthermore, valid non-invasive brain temperature monitoring is difficult in small rodents. This paper describes a method for both monitoring and maintenance of brain temperature during small animal preparations in a stereotaxic frame. The device used includes an ear-bar thermocouple probe and a small near-infrared radiator. The new equipment permitted to maintain peri-ischemic brain temperature at a desired level while carrying out non-invasive continuous record…
The Blood–Brain Barrier as a Target in Traumatic Brain Injury Treatment
2014
Traumatic brain injury (TBI) is one of the most frequent causes of death in the young population. Several clinical trials have unsuccessfully focused on direct neuroprotective therapies. Recently immunotherapeutic strategies shifted into focus of translational research in acute CNS diseases. Cross-talk between activated microglia and blood–brain barrier (BBB) could initiate opening of the BBB and subsequent recruitment of systemic immune cells and mediators into the brain. Stabilization of the BBB after TBI could be a promising strategy to limit neuronal inflammation, secondary brain damage and acute neurodegeneration. This review provides an overview on the pathophysiology of TBI and brain…
Improved Regeneration of Autologous Nerve Transplants by Means of VEGF-Gene Therapy
2009
The impact of the Vascular Endothelial Growth Factor (VEGF) on the angiogenic cascade is proven. Recently its neuroprotective effect after peripheral nerve injuries on α-motoneurons in the spinal cord was shown. Experiments on α-motoneurons demonstrated a decreased sensitivity to ischemia under VEGF-therapy. Aim of the study was to elucidate the effect of a localized VEGF-gene-therapy using an adenoviral vector construct in the model of a peripheral nerve defect in the rat treated with an autologous nerve transplant.
Modelling the Impacts of Climate Change on Dissolved Organic Carbon
2009
Dissolved organic carbon (DOC) from peat soils has implications both for the ecology of receiving waters and for the quality and treatment costs of water used for human consumption. Fluxes of DOC from peat soils are also relevant in the context of the global carbon cycle. Chapter 12 in this volume has reviewed the evidence for the effects of different environmental factors on the decomposition of peat soils and the export of DOC, drawing on literature and long-term data acquired from a number of European sites. The conclusion from this and many other studies is that, although there may be other influences such as land management and recovery from acid deposition, climate factors are a major…
Radiation protection in paediatrics age
2014
Radiological protection in paediatric population from medical imaging is a subject promoted by various international associations and it is becoming a main field of interest. Paediatric patients have a significant risk from ionizing radiation (IR) following X-ray examination (chest, abdomen and skeletal segments), multidetector CT (MDCT) and PET imaging [1]. Their greater damage’s risk is due to: growing tissues with elevated turnover and high radio sensitivity cellular, the high water content which amplifies the damage, the small body size that involves the exposure of large areas associated with the expectation of long- life makes possible the development of diseases resulting from geneti…
Peer to Consumer Lending
2022
Peer to consumer lending represents an alternative form of financing characterized, within the crowdfunding genus, by the collecting of credit offers to be matched with borrowing demand through a digital platform. The essay focuses on legal analysis of some aspects of the structure and the functioning of lending marketplaces operating in the sector at stake. The Author argues how this business model – especially when the phenomenon involves consumers and, more generally, non-professionals counterparts – may be critical as regards to the classical cathegories and concepts ruling the lending/borrowing discourse.
Socioeconomic and Medical Approaches upon Pensions Systems
2021
The social protection of citizens was an essential issue for all countries, regardless of the form of government, sociocultural characteristics, and economic system. In this chapter, we aim to identify the factors, which determined the configuration of the current pension systems implemented in the five CEE countries.
Overview of Pension Systems
2021
Understanding the configuration of social protection and pension systems can be achieved only from a sociohistorical perspective upon the framework in which these emerged and developed.
The comparative biological effects of spatial management measures in protecting marine biodiversity: a systematic review protocol
2015
Background: The global decline of marine biodiversity and the perceived need to protect marine ecosystems from irreparable alterations to ecosystem functioning and ecosystem service provision have produced an extensive range of spatial management measures (SMMs). The design of SMMs is a complex process often involving the integration of both conservation objectives and socio-economic priorities and the resultant trade-offs are highly dependent on the management regime in place. Future marine management is likely to involve greater use of different forms of protected areas with differing levels of protection, particularly for sites where there are multiple competing demands. Consequently, ev…
Problems of the Continental Permian in the Federal Republic of Germany
1976
The occurrences of Continental Permian in the Federal Republic of Germany are generally well understood but some problems remain. These are outlined and discussed in the present paper.