Search results for "Pyruvic Acid"

showing 3 items of 33 documents

Effects of lindane on fish carbohydrate metabolism.

1991

Exposure of the European eel (Anguilla anguilla) to a high sublethal concentration of 0.335 ppm (0.50 of the 96-hr LC50) of lindane for 6, 12, 24, 48, 72, and 96 hr affected carbohydrate metabolism. Muscle glycogen levels decreased significantly (P less than 0.05) at 6, 12, 24, 48, 72, and 96 hr; liver glycogen content did not decline at any time. Muscle glucose levels in fish were elevated at 6, 12, 24, 48, 72, and 96 hr but in liver, the levels increased only at 96 hr. Mean values of muscle and liver pyruvate were elevated significantly (P less than 0.05) at 6, 12, 24, 48, and 72 hr. Muscle lactate levels increased at 6, 12, 24, and 48 hr in pesticide-treated fish. Liver lactate levels we…

medicine.medical_specialtyHealth Toxicology and MutagenesisCarbohydrate metabolismBiologychemistry.chemical_compoundInternal medicinemedicineAnimalsGlycogenMusclesPublic Health Environmental and Occupational HealthGeneral MedicinePesticideCarbohydrateAnguillaPollutionEndocrinologychemistryLiverSpainToxicityFish <Actinopterygii>Carbohydrate MetabolismPyruvic acidLindaneHexachlorocyclohexaneEcotoxicology and environmental safety
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Lindane-induced changes in carbohydrate metabolism in Anguilla anguilla

1992

Abstract 1. Anguilla anguilla (L.) was exposed to a sublethal concentration of 0.167 ppm (0.25 of the 96-hr lc 50 ) of lindane for 6, 12, 24, 48, 72 and 96 hr. 2. Changes in glycogen, glucose, pyruvate and lactate contents of liver and muscle after lindane exposure, were studied. 3. Muscle and liver glycogen levels decreased significantly during the exposure time. Muscle glucose values increased but on the other hand we found a decrease in those of liver. 4. Muscle and liver pyruvate content increased as did lactate levels in both tissues. 5. The observed effects of lindane on carbohydrate metabolism in fish are discussed in relation to acute stress syndrome.

medicine.medical_specialtyImmunologyBiologyCarbohydrate metabolismchemistry.chemical_compoundInternal medicinePyruvic AcidmedicineAnimalsLactic AcidAcute stressPyruvatesPharmacologyGlycogenMusclesMetabolismCarbohydrateAnguillaGlucoseEndocrinologyLiverchemistryLactatesCarbohydrate MetabolismFish <Actinopterygii>LindaneGlycogenHexachlorocyclohexaneComparative Biochemistry and Physiology Part C: Comparative Pharmacology
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Effects of severe arterial hypocapnia on regional blood flow regulation, tissuePO2 and metabolism in the brain cortex of cats

1981

The effect of a stepwise decrease in PaCO2 from 3.9-1.6 kPa on rCBF, rCMRO2, tissue PO2 and concentrations of glucose, lactate, pyruvate, ATP, ADP, AMP and phosphocreatine in the brain cortex was studied in cats lightly anaesthetized with sodium pentobarbital. 1. Moderate lowering of PaCO2 to 2.5 kPa induced in all animals a homogeneous decrease of rCBF in corresponding areas of the right and left hemisphere. Mean rCBF fell from 129.2 to 103.1 ml X 100 g-1 X min-1, while rCMRO2 remained unchanged (12.7-12.9 ml X 100 g-1 X min-1). The tissue PO2 frequency histograms showed a shift to lower values without indicating the presence of brain tissue hypoxia. 2. Severe arterial hypocapnia (PaCO2 = …

medicine.medical_specialtyPhosphocreatinePhysiologyClinical BiochemistryPhosphocreatinechemistry.chemical_compoundOxygen ConsumptionHypocapniaAdenine nucleotidePhysiology (medical)Internal medicinePyruvic AcidHyperventilationmedicineAnimalsHyperventilationLactic AcidPyruvatesCerebral CortexAdenine NucleotidesCarbon DioxideHypoxia (medical)medicine.diseaseOxygenGlucoseEndocrinologymedicine.anatomical_structurechemistryCerebral cortexCerebrovascular CirculationAnesthesiaCatsLactatesVascular resistanceVascular ResistancePyruvic acidmedicine.symptomcirculatory and respiratory physiologyPflügers Archiv - European Journal of Physiology
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