Search results for "Q10"

Autism and Intellectual Disability Associated with Mitochondrial Disease and Hyperlactacidemia

2015

Autism spectrum disorder (ASD) with intellectual disability (ID) is a life-long debilitating condition, which is characterized by cognitive function impairment and other neurological signs. Children with ASD-ID typically attain motor skills with a significant delay. A sub-group of ASD-IDs has been linked to hyperlactacidemia and alterations in mitochondrial respiratory chain activity. The objective of this report is to describe the clinical features of patients with these comorbidities in order to shed light on difficult diagnostic and therapeutic approaches in such patients. We reported the different clinical features of children with ID associated with hyperlactacidemia and deficiencies i…

On the shape of compact hypersurfaces with almost constant mean curvature

2015

The distance of an almost constant mean curvature boundary from a finite family of disjoint tangent balls with equal radii is quantitatively controlled in terms of the oscillation of the scalar mean curvature. This result allows one to quantitatively describe the geometry of volume-constrained stationary sets in capillarity problems.

Variations in physiological responses to thermal stress in congeneric limpets in the Mediterranean Sea

2014

Cardiac activity (Arrhenius breakpoint temperatures and Q10 relationships) and heat shock response (hsp70 expression) were measured in the congeneric limpets Patella rustica, P. caerulea and P. ulyssiponensis in order to test the relationship between their vertical distribution and physiological thermal tolerance. These species exhibit different vertical distributions along Mediterranean shores and despite the narrow tidal range in the Mediterranean, they experience different environmental conditions and consequently had specific thermal windows. Cardiac activity of the upper zoned P. rustica was maintained at higher temperatures than its mid- or low shore counterparts, P. caerulea and P. u…

Current Experience in Testing Mitochondrial Nutrients in Disorders Featuring Oxidative Stress and Mitochondrial Dysfunction: Rational Design of Chemo…

2014

An extensive number of pathologies are associated with mitochondrial dysfunction (MDF) and oxidative stress (OS). Thus, mitochondrial cofactors termed "mitochondrial nutrients" (MN), such as alpha-lipoic acid (ALA), Coenzyme Q10 (CoQ10), and L-carnitine (CARN) (or its derivatives) have been tested in a number of clinical trials, and this review is focused on the use of MN-based clinical trials. The papers reporting on MN-based clinical trials were retrieved in MedLine up to July 2014, and evaluated for the following endpoints: (a) treated diseases; (b) dosages, number of enrolled patients and duration of treatment; (c) trial success for each MN or MN combinations as reported by authors. The…

On the regularity of critical and minimal sets of a free interface problem

2015

We study a free interface problem of finding the optimal energy configuration for mixtures of two conducting materials with an additional perimeter penalization of the interface. We employ the regularity theory of linear elliptic equations to study the possible opening angles of Taylor cones and to give a different proof of a partial regularity result by Fan Hua Lin [Calc Var. Partial Differential Equations, 1993].

Toward the definition of a carbon budget model: seasonal variation and temperature effect on respiration rate of vegetative and reproductive organs o…

2009

Summary This study, as a preliminary step toward the definition of a carbon budget model for pistachio trees (Pistacia vera L.), aimed at estimating and evaluating the dynamics of respiration of vegetative and reproductive organs of pistachio tree. Trials were performed in 2005 in a commercial orchard located in Sicily (370 m a.s.l.) on five bearing 20-year-old pistachio trees of cv. Bianca grafted onto Pistachio terebinthus L. Growth analyses and respiration measurements were done on vegetative (leaf) and reproductive (infructescence) organs during the entire growing season (April–September) at biweekly intervals. Results suggested that the respiration rates of pistachio reproductive and v…

Expecting the unexpected: Quantifying the persistence of unexpected hypersurfaces

2021

If $X \subset \mathbb P^n$ is a reduced subscheme, we say that $X$ admits an unexpected hypersurface of degree $t$ for multiplicity $m$ if the imposition of having multiplicity $m$ at a general point $P$ fails to impose the expected number of conditions on the linear system of hypersurfaces of degree $t$ containing $X$. Conditions which either guarantee the occurrence of unexpected hypersurfaces, or which ensure that they cannot occur, are not well understand. We introduce new methods for studying unexpectedness, such as the use of generic initial ideals and partial elimination ideals to clarify when it can and when it cannot occur. We also exhibit algebraic and geometric properties of $X$ …

UN MODELLO EMPIRICO DI EMISSIONE DI CO2 DAL SUOLO: CURVE DI RISPOSTA ALLA TEMPERATURA ED ALL'UMIDITÀ DEL SUOLO DI UN AGROECOSISTEMA MEDITERRANEO

2012

Il presente lavoro è stato condotto su suolo prelevato all’interno di un oliveto con l’obiettivo di valutare il tasso di respirazione attribuibile alla componente eterotrofa (microbica) in funzione dei fattori temperatura ed umidità. Il tasso di respirazione è stato monitorato su suolo incubato a cinque livelli di temperatura, 10-15-20-25-30 °C e a quattro livelli del contenuto idrico volumetrico del suolo (θ) 12,6-18,9-25,2-31,5 % (v/v). I valori di respirazione hanno presentato un range di valori variabili tra 78,20 e 14,81 µg CO2 g-1 soil d-1 rispettivamente a 30°C e 10°C e a 12,6 e 31,5 %. I valori di Q10, ovvero la risposta della respirazione in relazione agli incrementi di temperatura…

The effects of extra-virgin olive oil supplemented with Vit. E and Q10 on plasma antioxidant capacity and aerobic performance in athletes

2010

Climate and agriculture: empirical evidence for countries and agroecological zones of the Sahel

2022

International audience; ow heterogenous is the impact of climate change across space and the type of agricultural production? In this paper, we investigate the relationship between climate change and variability, measured by temperature and rainfall, and agricultural production at the country and agroecological zone levels of the Sahel. We consider a crop production index and five cereals (maize, millet, sorghum, wheat and rice). Based on an original climate database and an agricultural production function estimated for the period 1961–2016, we show that average rainfall and temperature during the growing season indeed have highly heterogeneous effects on agricultural production, depending …