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showing 10 items of 591 documents

REAL-TIME-PCR PER LA QUANTIZZAZIONE DI CMV-DNA DA SANGUE INTERO NEL FOLLOW-UP DI PAZIENTI TRAPIANTATI

2006

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lcsh:QR1-502General Medicinelcsh:MicrobiologyMicrobiologia Medica
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Comparative ultrastructure and carbohydrate composition of gastroliths from Astacidae, Cambaridae and Parastacidae freshwater crayfish (Crustacea, De…

2012

21 pages; International audience; Crustaceans have to cyclically replace their rigid exoskeleton in order to grow. Most of them harden this skeleton by a calcification process. Some decapods (land crabs, lobsters and crayfish) elaborate calcium storage structures as a reservoir of calcium ions in their stomach wall, as so-called gastroliths. For a better understanding of the cyclic elaboration of these calcium deposits, we studied the ultrastructure of gastroliths from freshwater crayfish by using a combination of microscopic and physical techniques. Because sugars are also molecules putatively involved in the elaboration process of these biomineralizations, we also determined their carbohy…

lcsh:QR1-502carbohydratesAstacidea010402 general chemistry01 natural sciencesBiochemistrylcsh:MicrobiologyArticlecalcification03 medical and health scienceschemistry.chemical_compoundAstacidaeMalacostracaCrustacea14. Life underwatercalcium storage[SDV.IB.BIO]Life Sciences [q-bio]/Bioengineering/BiomaterialsMolecular Biology030304 developmental biologyorganic matrix0303 health sciencesbiologycrayfishDecapodaEcologybiology.organism_classificationCrayfish[ SDV.IB.BIO ] Life Sciences [q-bio]/Bioengineering/Biomaterialsbiomineralization6. Clean waterCambaridaeAmorphous calcium carbonate0104 chemical sciencesBiochemistrychemistryGastrolithgastrolithproteoglycans
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RUOLO DELL’INFEZIONE OCCULTA DA HBV NEL PAZIENTE IMMUNOCOMPROMESSO

2005

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lcsh:QR1-502lcsh:MicrobiologyMicrobiologia Medica
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The Role of Fructose as a Cardiovascular Risk Factor: An Update

2022

There is increasing presence of fructose in food and drinks, and some evidence suggests that its higher consumption increases cardiovascular risk, although the mechanisms still remain not fully elucidated. Cardiovascular diseases (CVD) are still responsible for one-third of deaths worldwide, and therefore, their prevention should be assessed and managed comprehensively and not by the evaluation of individual risk factor components. Lifestyle risk factors for CVD include low degree of physical activity, high body mass index, alcohol consumption, smoking, and nutritional factors. Indeed, nutritional risk factors for CVD include unhealthy dietary behaviors, such as high intake of refined foods…

lipoproteinsCardiovascular disease Fructose Lipoproteins Nutrition Risk factorsnutritioncardiovascular diseaseEndocrinology Diabetes and MetabolismPerspectiverisk factorsMolecular BiologyBiochemistryMicrobiologyQR1-502fructose
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Microencapsulation of Enteric Bacteriophages in a pH-Responsive Solid Oral Dosage Formulation Using a Scalable Membrane Emulsification Process

2019

A scalable low-shear membrane emulsification process was used to produce microencapsulated Escherichia coli-phages in a solid oral dosage form. Uniform pH-responsive composite microparticles (mean size ~100 &micro

maha-suolitulehduslcsh:RS1-441Pharmaceutical Sciencebacteriophage therapy<i>E. coli</i>ArticleDosage formbakteriofagitRSlaw.inventionlääkesuunnittelulcsh:Pharmacy and materia medica03 medical and health sciencesConfocal microscopylawEscherichiaenterobakteeritMembrane emulsification030304 developmental biology0303 health sciencesChromatographybiologykalvot (tekniikka)030306 microbiologyChemistryenteric infectionsE. colibiology.organism_classificationControlled releaseIn vitroQR3. Good healthfagiterapiamikrorakenteetpH-triggered releaseCell cultureGastric acidmicroencapsulationcontrolled releaseEudragit S100Pharmaceutics
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Genetic influences on resting electrocardiographic variables in older women: a twin study.

2009

Background: Previous studies in young and middle-aged men and women have shown that resting electrocardiographic (ECG) variables are influenced by genetic factors. However, the extent to which resting ECG variables are influenced by genetic factors in older women is unknown. Thus, the aim of this study was to estimate the relative contribution of genetic and environmental influences to individual differences in resting ECG variables among older female twins without overt cardiac diseases. Methods: Resting ECG recordings were obtained from 186 monozygotic and 203 dizygotic twin individuals, aged 63–76 years. Quantitative genetic modeling was used to decompose the phenotypic variance in each …

medicine.medical_specialtyAgingDizygotic twinRestTwins030204 cardiovascular system & hematologyQT intervalCohort Studies03 medical and health sciencesQRS complexElectrocardiography0302 clinical medicineHeart RateReference ValuesPhysiology (medical)Internal medicineHeart ratemedicineConfidence IntervalsTwins DizygoticHumansGenetic Predisposition to Diseasecardiovascular diseasesFinland030304 developmental biologyAged0303 health sciencesmedicine.diagnostic_testbusiness.industryGeneral MedicineTwins MonozygoticOriginal ArticlesHeritabilityMiddle AgedTwin studyConfidence intervalEndocrinologyCardiologyFemaleCardiology and Cardiovascular MedicinebusinessElectrocardiographyAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc
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Awake Surgery: Skills of Neurosurgeon Matter but Those of Patient Too. How to Optimize Functional Brain Mapping by Improving Per-Operatory Testing?

2011

International audience; It is now possible to perform resections of slowgrowing tumors in awake patients. Using direct electrical stimulation (DES), real-time functional mapping of the brain can be used to prevent the resection of essential areas near the tumor. For now, simple clinical tests are performed on conscious patients and combined with DES in order to discriminate functional and non-functional areas invaded by the tumors. In this work we try to develop a simple device based on a simple technology to better quantify the performances of the patients during the surgery itself and give a real-time feedback to the neurosurgeon that will help to further guide the surgery by improving th…

medicine.medical_specialtyClinical testsEnvironmental Engineeringlcsh:QP1-981business.industry[SCCO.NEUR]Cognitive science/Neurosciencelcsh:QR1-502lcsh:Microbiologylcsh:PhysiologyIndustrial and Manufacturing EngineeringSurgeryResection[SPI.AUTO]Engineering Sciences [physics]/AutomaticFunctional brainFunctional mapping[ SPI.AUTO ] Engineering Sciences [physics]/Automaticlcsh:Zoology[ SCCO.NEUR ] Cognitive science/NeurosciencemedicineMedical physicslcsh:QL1-991NeurosurgerybusinessAwake surgery
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Glycolysis Metabolites and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Trial

2021

The increased prevalence of atrial fibrillation (AF) and heart failure (HF) highlights the need to better understand the mechanisms underlying these cardiovascular diseases (CVDs). In the present study, we aimed to evaluate the association between glycolysis-related metabolites and the risk of AF and HF in a Mediterranean population at high risk of CVD. We used two case-control studies nested within the PREDIMED trial. A total of 512 incident AF cases matched to 734 controls, and 334 incident HF cases matched to 508 controls, were included. Plasma metabolites were quantified by using hydrophilic interaction liquid chromatography coupled with high-resolution negative ion mode MS detection. C…

medicine.medical_specialtyEndocrinology Diabetes and MetabolismPopulationheart failureHeart failure030204 cardiovascular system & hematologyBiochemistryMicrobiologyPathogenesis03 medical and health sciences0302 clinical medicineInternal medicinemedicineGlycolysisatrial fibrillation030212 general & internal medicineeducationMolecular Biologyeducation.field_of_studybusiness.industryBrief ReportAtrial fibrillationPREDIMED studyglycolysismedicine.diseasePredimedAtrial fibrillationQR1-502Increased riskHeart failureCardiologyConditional logistic regressionbusinessGlycolysis
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Proteinuria-Lowering Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibitors in Chronic Kidney Disease Patients: A Real-World Multicentri…

2021

Control of dyslipidemia in chronic kidney disease (CKD) is not always guaranteed with statins and/or ezetimibe. Proprotein convertase subtilisin/kexin type 9 inhibitors (PCSK9i) have opened up a new era in lipid control, but their effect on renal function and proteinuria in real life have not yet been evaluated. The aim of the present study was to analyze the evolution of renal function and proteinuria in a cohort of CKD patients treated with PCSK9i. This retrospective multicentric cohort study included CKD patients treated with PCSK9i. Baseline epidemiological data, comorbidities and laboratory findings (including estimated glomerular filtration rate [eGFR], proteinuria and lipid profile) …

medicine.medical_specialtyEndocrinology Diabetes and MetabolismUrologyRenal functionurologic and male genital diseasesMicrobiologyBiochemistryArticleNephrotoxicitychemistry.chemical_compoundEzetimibePCSK9iCKDmedicinekidney functionMolecular BiologyCreatinineProteinuriamedicine.diagnostic_testbusiness.industrymedicine.diseaseQR1-502female genital diseases and pregnancy complicationschemistryInsuficiència renal crònicaproteinuriamedicine.symptomLipid profilebusinessDyslipidemiaKidney diseasemedicine.drugMetabolites
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The global distribution of lymphatic filariasis, 2000–18:a geospatial analysis

2020

Background Lymphatic filariasis is a neglected tropical disease that can cause permanent disability through disruption of the lymphatic system. This disease is caused by parasitic filarial worms that are transmitted by mosquitos. Mass drug administration (MDA) of antihelmintics is recommended by WHO to eliminate lymphatic filariasis as a public health problem. This study aims to produce the first geospatial estimates of the global prevalence of lymphatic filariasis infection over time, to quantify progress towards elimination, and to identify geographical variation in distribution of infection. Methods A global dataset of georeferenced surveyed locations was used to model annual 2000–18 lym…

medicine.medical_specialtyGeospatial analysis030231 tropical medicineElephantiasis:ELIMINATIONcomputer.software_genreArticleLocal Burden of Disease 2019 Neglected Tropical Diseases Collaborators1117 Public Health and Health Services03 medical and health sciences0302 clinical medicineRA0421Environmental healthGlobal healthmedicine030212 general & internal medicineMass drug administrationLymphatic filariasisPublic healthlcsh:Public aspects of medicineTropical diseaselcsh:RA1-1270General Medicinemedicine.disease3. Good healthQRGeographyLymphatic systemITC-ISI-JOURNAL-ARTICLEA990 Medicine and Dentistry not elsewhere classifiedITC-GOLDcomputer0605 Microbiology
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