Search results for "Quadrupole"

showing 10 items of 460 documents

Permanent magnet system to guide superparamagnetic particles

2017

A new concept of permanent magnet systems for guiding superparamagnetic particles on arbitrary trajectories is proposed. The basic concept is to use one magnet system with a strong and homogeneous (dipolar) magnetic field to magnetize and orient the particles. A second constantly graded field (quadrupolar) is superimposed to the first to generate a force. In this configuration the motion of the particles is driven solely by the component of the gradient field which is parallel to the direction of the homogeneous field. Then the particles are guided with constant force in a single direction over the entire volume. The direction can be adjusted by varying the angle between quadrupole and dipo…

010302 applied physicsPhysicsMagnetic momentCondensed matter physicsFOS: Physical sciences02 engineering and technologyMechanics021001 nanoscience & nanotechnologyCondensed Matter PhysicsPolarization (waves)Physics - Medical Physics01 natural sciencesElectronic Optical and Magnetic MaterialsMagnetic fieldDipoleMagnet0103 physical sciencesQuadrupoleVector fieldMedical Physics (physics.med-ph)0210 nano-technologyQuadrupole magnetJournal of Magnetism and Magnetic Materials
researchProduct

Analysis of psychoactive substances in water by information dependent acquisition on a hybrid quadrupole time-of-flight mass spectrometer.

2016

Emerging drugs of abuse, belonging to many different chemical classes, are attracting users with promises of “legal” highs and easy access via internet. Prevalence of their consumption and abuse through wastewater-based epidemiology can only be realized if a suitable analytical screening procedure exists to detect and quantify them in water. Solid-phase extraction and ultra-high performance liquid chromatography quadrupole time-of-flight-mass spectrometry (UHPLC–QqTOF–MS/MS) was applied for rapid suspect screening as well as for the quantitative determination of 42 illicit drugs and metabolites in water. Using this platform, we were able to identify amphetamines, tryptamines, piperazines, p…

010501 environmental sciencesWastewaterMass spectrometryTandem mass spectrometry01 natural sciencesBiochemistryRiver waterHigh resolution mass spectrometryAnalytical ChemistryRiversTandem Mass SpectrometryQuantificationPsychoactive drugsHumansSample preparationSolid phase extractionQuadrupole time of flightChromatography High Pressure Liquid0105 earth and related environmental sciencesPsychotropic DrugsChromatographyChemistryIllicit Drugs010401 analytical chemistryOrganic ChemistrySolid Phase ExtractionWaterGeneral MedicineQuantitative determination0104 chemical sciencesWastewaterEnvironmental chemistryScreeningDatabases ChemicalWater Pollutants ChemicalJournal of chromatography. A
researchProduct

Metabolic signatures across the full spectrum of non-alcoholic fatty liver disease.

2022

Funder: European Commission

ALTtype 2 diabetes mellitusROC receiving operator characteristicaspartate aminotransferaseHSDLDL low-density lipoproteinUHPLC ultrahigh-performance liquid chromatographyROCHCCNon-alcoholic steatohepatitisGCPCANASHGastroenterology2-HB 2-hydroxybutanoic acid; 3-HB 3-hydroxybutanoic acid; ALT alanine aminotransferase; AST aspartate aminotransferase; CE cholesterol ester; Cer ceramide; FFA free fatty acid; FLIP Fatty Liver Inhibition of Progression; Fibrosis; GC gas chromatography; HCC hepatocellular carcinoma; HSD honest significant difference; LC lipid cluster; LDL low-density lipoprotein; LM lipid and metabolite; LMC lipid metabolite and clinical variable; LPC lysophosphatidylcholine; Lipidomics; Mass spectrometry; Metabolomics; NAFL non-alcoholic fatty liver; NAFLD non-alcoholic fatty liver disease; NAS NASH activity score; NASH non-alcoholic steatohepatitis; NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network; NRR non-rejection rate; Non-alcoholic steatohepatitis; PC(O) ether PC; PC phosphatidylcholine; PCA principal component analysis; PE phosphatidylethanolamine; QTOFMS quadrupole-time-of-flight mass spectrometry; ROC receiving operator characteristic; SAF steatosis activity and fibrosis; SM sphingomyelin; T2DM type 2 diabetes mellitus; TG triacylglycerol; UHPLC ultrahigh-performance liquid chromatographySAFSAF steatosis activity and fibrosisLM lipid and metabolitehonest significant differenceHSD honest significant differenceTG triacylglycerolnon-rejection ratecholesterol esterPCPEGC gas chromatographyfree fatty acidFLIPNASH non-alcoholic steatohepatitisNIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkBIOMARKERST2DMPE phosphatidylethanolamineLDLlipidNAFLDFFA free fatty acid2-HBMetabolomicsNAFL non-alcoholic fatty liverLMCphosphatidylcholineScience & TechnologySM sphingomyelinGastroenterology & HepatologyMass spectrometryactivitynutritional and metabolic diseasesT2DM type 2 diabetes mellitusACIDSreceiving operator characteristicdigestive system diseasesquadrupole-time-of-flight mass spectrometryLC lipid clusterlow-density lipoproteinNAS2-HB 2-hydroxybutanoic acidNAS NASH activity scoreQTOFMSether PCNRRSCORING SYSTEMprincipal component analysisgas chromatographyLC2-hydroxybutanoic acidPROGRESSIONAST aspartate aminotransferaseLMPC phosphatidylcholinePC(O)MARKERSUHPLCsteatosisTOOLImmunology and AllergyINSULIN-RESISTANCECerSMFatty Liver Inhibition of Progressionhepatocellular carcinoma2-HB 2-hydroxybutanoic acid NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network NRR non-rejection rate Non-alcoholic steatohepatitis PC(O) ether PC PC phosphatidylcholine PCA principal component analysis PE phosphatidylethanolamine QTOFMS quadrupole-time-of-flight mass spectrometry ROC receiving operator characteristic SAF steatosis activity and fibrosis SM T2DM type 2 diabetes mellitus TG triacylglycerol UHPLC ultrahigh-performance liquid chromatographyultrahigh-performance liquid chromatographyCELPC3-HBNAFLnon-alcoholic fatty liverTGtriacylglycerolNRR non-rejection rateLife Sciences & BiomedicineNAFLD non-alcoholic fatty liver diseaseFLIP Fatty Liver Inhibition of Progressionalanine aminotransferasemetaboliteCer ceramideCE cholesterol estersphingomyelinlysophosphatidylcholineand fibrosisALT alanine aminotransferaseInternal MedicineceramideNational Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkAST3-HB 3-hydroxybutanoic acidQTOFMS quadrupole-time-of-flight mass spectrometryPCA principal component analysisLPC lysophosphatidylcholineHepatologynon-alcoholic fatty liver diseaseand clinical variablePC(O) ether PC3-hydroxybutanoic acidFibrosisNASH activity scoreNIDDK NASH-CRNlipid clusterlipid and metabolitephosphatidylethanolamineLipidomicsLMC lipid metabolite and clinical variableFFAHCC hepatocellular carcinomaJHEP reports : innovation in hepatology
researchProduct

Size-consistent ab initio calculation of the electric quadrupole moment of Cl2

2003

Abstract The molecular electric quadrupole moment ( Θ ) of Cl 2 has been calculated using SDCI, and (SC) 2 -SDCI wave functions as well as CCSD, CCSD(T), and CC3 methods. All these correlation methods are single reference. All of them, but SDCI, are free of the size-extensivity error. The variation of Θ from the separated atoms to the equilibrium region is reported. The present results leads to an estimated value of 2.3520 a.u. (10.55 × 10 −40 Cm 2 ) corresponding to a CC(3) calculation at the CBS approach and including the ro-vibrational and thermal averaging corrections. This value is compatible with two experimental values and points to one of them as slightly more reliable.

Ab initio quantum chemistry methodsChemistryThermalQuadrupoleAb initioGeneral Physics and AstronomyCorrelation methodPhysical and Theoretical ChemistryAtomic physicsWave functionBond-dissociation energyDiatomic moleculeChemical Physics Letters
researchProduct

Asymptotic potentials and rate constants in the adiabatic capture centrifugal sudden approximation for X + OH(X-2 Pi) -> OX + H(S-2) reactions where …

2012

International audience; New long-range multipolar coefficients for the X + OH(X-2 Pi) interactions, where X = O(P-3), S(P-3) and N(S-4), are given here. They have been evaluated on the basis or monomer properties of the atoms and OH such as the dipole and quadrupole moments, and the static and dynamic polarizabilities. Each matrix element of the 18 x 18 (8 x 8 for N + OH) quasi-degenerate asymptotic potentials has been built up by means of the perturbation theory up to second order including or not the fine-structure of O, S and OH. The adiabatic potentials, obtained after diagonalization of the full matrix, show many crossings and complex behaviors near the asymptotes. Using the entrance c…

Ab initio010402 general chemistryKinetic energy7. Clean energy01 natural sciencesBiochemistryDIPOLE POLARIZABILITIESATOMSAb initio quantum chemistry methodsLOW-TEMPERATUREOH RADICALS0103 physical sciencesCOUPLED-CLUSTER CALCULATIONSPhysical and Theoretical ChemistryPerturbation theoryAdiabatic processKINETICS010304 chemical physicsChemistryRANGECondensed Matter PhysicsPotential energy0104 chemical sciencesQUADRUPOLE-MOMENTSO-2[SDU]Sciences of the Universe [physics]QuadrupoleCLAtomic physicsGround state
researchProduct

Rotational spectra and hyperfine structure of isotopic species of deuterated cyanoacetylene, DC3N

2008

Abstract Cyanoacetylene enriched in deuterium was used to record pure rotational transitions of DC 3 N and its rare 13 C and 15 N isotopic species by employing Fourier transform microwave (FTMW) spectroscopy on a supersonic-jet expansion at centimeter wavelengths (8.2–25.4 GHz) and by using long-path absorption spectroscopy at millimeter and submillimeter wavelengths (82–900 GHz). In addition, submillimeter wave measurements (304–897 GHz) have been performed for DC 3 N in its v 7 = 1 lowest excited vibrational state. Hyperfine structure caused by the 14 N and D nuclei has been resolved in the FTMW spectra. Quantum-chemical calculations have been performed on the hyperfine structure paramete…

Absorption spectroscopyChemistryAnalytical chemistryGeneral Physics and Astronomychemistry.chemical_compoundDeuteriumExcited stateQuadrupoleCyanoacetyleneRotational spectroscopyPhysical and Theoretical ChemistryAtomic physicsSpectroscopyHyperfine structureAstrophysics::Galaxy AstrophysicsChemical Physics
researchProduct

Design of a 10 GHz minimum-B quadrupole permanent magnet electron cyclotron resonance ion source

2020

This paper presents a simulation study of a permanent magnet electron cyclotron resonance ion source (ECRIS) with a minimum-B quadrupole magnetic field topology. The magnetic field is made to conform to conventional ECRIS with $B_\textrm{min}/B_\textrm{ECR}$ of 0.67 and a last closed magnetic isosurface of 1.86$B_\textrm{ECR}$ at 10 GHz. The distribution of magnetic field gradients parallel to the field, affecting the electron heating efficiency, cover a range from 0 to 13 T/m, being similar to conventional ECRIS. Therefore it is expected that the novel ion source produces warm electrons and high charge state ions in significant number. Single electron tracking simulations are used to estim…

Accelerator Physics (physics.acc-ph)PhysicsIon beam analysis010308 nuclear & particles physicsFOS: Physical sciencesElectron01 natural sciences7. Clean energyIon sourceElectron cyclotron resonance030218 nuclear medicine & medical imagingIon03 medical and health sciences0302 clinical medicineBeamlinePhysics::Plasma PhysicsMagnet0103 physical sciencesQuadrupolePhysics::Accelerator PhysicsPhysics - Accelerator PhysicsAtomic physicsInstrumentationMathematical PhysicsJournal of Instrumentation
researchProduct

Characterization and Tuning of Ultra High Gradient Permanent Magnet Quadrupoles

2009

The application of quadrupole devices with high field gradients and small apertures requires precise control over higher order multipole field components. We present a new scheme for performance control and tuning, which allows the illumination of most of the quadrupole device aperture because of the reduction of higher order field components. Consequently, the size of the aperture can be minimized to match the beam size achieving field gradients of up to $500\text{ }\text{ }\mathrm{T}\text{ }{\mathrm{m}}^{\ensuremath{-}1}$ at good imaging quality. The characterization method based on a Hall probe measurement and a Fourier analysis was confirmed using the high quality electron beam at the M…

Accelerator Physics (physics.acc-ph)electron beamNuclear and High Energy PhysicsPhysics - Instrumentation and DetectorscompactmagneticlensPhysics and Astronomy (miscellaneous)Field (physics)AperturemultipoleFOS: Physical sciencespermanenthalbachx-felNuclear magnetic resonancetuningquadrupolelcsh:Nuclear and particle physics. Atomic energy. RadioactivityQuadrupole magnetMicrotronPhysicsOrder (ring theory)Surfaces and InterfacesInstrumentation and Detectors (physics.ins-det)beam focusingComputational physicsMagnetQuadrupolelcsh:QC770-798Physics::Accelerator PhysicsPhysics - Accelerator PhysicsMultipole expansion
researchProduct

Multi-mycotoxin analysis in wheat semolina using an acetonitrile-based extraction procedure and gas chromatography–tandem mass spectrometry

2012

A new analytical method for the rapid and simultaneous determination of ten mycotoxins including patulin, zearalenone and eight trichothecenes (nivalenol, fusarenon-X, diacetoxyscirpenol, 3-acetyl-deoxynivalenol, neosolaniol, deoxynivalenol, T-2 and HT-2) in wheat semolina has been developed and optimized. Sample extraction and purification were performed with a modified QuEChERS-based (acronym of Quick, Easy, Cheap, Effective, Rugged and Safe) procedure and determined by gas chromatography (GC) coupled to triple quadrupole instrument (QqQ). This is the first paper on the application of GC-QqQ-MS/MS to analysis of mycotoxins. Careful optimization of the gas chromatography-tandem mass spectr…

AcetonitrilesChromatographyGas Chromatography/Tandem Mass SpectrometryCalibration curveFlourLiquid-Liquid ExtractionOrganic ChemistryAnalytical chemistryReproducibility of ResultsGeneral MedicineHydrogen-Ion ConcentrationMycotoxinsQuechersSensitivity and SpecificityBiochemistryGas Chromatography-Mass SpectrometryDiacetoxyscirpenolAnalytical ChemistryTriple quadrupole mass spectrometerPatulinchemistry.chemical_compoundchemistryTandem Mass SpectrometryGas chromatographyGas chromatography–mass spectrometryJournal of Chromatography A
researchProduct

First experimental proof of asymmetric charge transfer in ICP-MS/MS (ICP-QQQ-MS) through isotopically enriched oxygen as cell gas

2014

The quantification of a variety of elements in the field of ICP-MS is restricted by isobaric interferences. The recent development of ICP-MS/MS (“triple quadrupole” configuration) offers a new way to solve the problem of the detection of such elements affected by interferences because the signal caused by either the analyte or the isobaric interference can be shifted to another m/z through reactions with the cell gas (oxygen, ammonia or hydrogen). This system consists of two quadrupoles (Q1 and Q2) with a collision/reaction cell in between. When using the MS/MS mode of this configuration it becomes possible to restrict the ions entering the cell to a defined m/z and therefore get a better i…

AnalyteHydrogenAnalytical chemistrychemistry.chemical_elementOxygenAnalytical ChemistryTriple quadrupole mass spectrometerIonAmmoniachemistry.chemical_compoundchemistryIsobaric processInductively coupled plasma mass spectrometrySpectroscopyJournal of Analytical Atomic Spectrometry
researchProduct