Search results for "R-factor"

showing 3 items of 3 documents

Characterization of the Clinical and Immunologic Phenotype and Management of 157 Individuals with 56 Distinct Heterozygous NFKB1 Mutations

2020

Contains fulltext : 229571.pdf (Publisher’s version ) (Closed access) BACKGROUND: An increasing number of NFKB1 variants are being identified in patients with heterogeneous immunologic phenotypes. OBJECTIVE: To characterize the clinical and cellular phenotype as well as the management of patients with heterozygous NFKB1 mutations. METHODS: In a worldwide collaborative effort, we evaluated 231 individuals harboring 105 distinct heterozygous NFKB1 variants. To provide evidence for pathogenicity, each variant was assessed in silico; in addition, 32 variants were assessed by functional in vitro testing of nuclear factor of kappa light polypeptide gene enhancer in B cells (NF-κB) signaling. RESU…

0301 basic medicineMaleNF-KAPPA-BMedizinlnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]Fluorescent Antibody TechniqueAutoimmunityDiseaseNUCLEAR-FACTORKaplan-Meier Estimatemedicine.disease_causeHypogammaglobulinemia0302 clinical medicineNFKB1 variants and mutations; autosomal dominant inheritance; common variable immunodeficiency; reduced penetrance; variable expressivityHDE PEDImmunology and Allergyvariants and mutationsNF-κB1-related phenotypeImmunodeficiencyIMMUNODEFICIENCY*NF-?B1-related phenotypeNFKB1 variants and mutations1184 Genetics developmental biology physiologycommon variable immunodeficiencyDisease ManagementMiddle AgedNF-kappa B1-related phenotypereduced penetrancePrognosisPenetranceImmunohistochemistryMagnetic Resonance Imaging3. Good healthPhenotypeNFKB1 variant*NFKB1 variant*common variable immunodeficiencyFemaleHaploinsufficiency*reduced penetranceNFKB1 mutationAdultHeterozygote*NFKB1 mutationImmunologyHAPLOINSUFFICIENCYArticle03 medical and health sciencesvariable expressivityautosomal dominantmedicineHumansGenetic Predisposition to DiseaseGenetic Association StudiesAgedbusiness.industryCommon variable immunodeficiencyNF-kappa B p50 SubunitNF-KAPPA-B1Immune dysregulationmedicine.diseaseautosomal dominant inheritance030104 developmental biologyBiological Variation PopulationImmunologyCELLSMutation*autosomal dominantPrimary immunodeficiency3111 BiomedicinebusinessTomography X-Ray ComputedBiomarkers030215 immunology
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Influence of the rainfall measurement interval on the erosivity determinations in the Mediterranean area

2006

Summary The single-storm erosion index, EI, of the USLE and RUSLE models may vary appreciably with the rainfall measurement interval, Δ t . However, the effect of Δ t on EI has not been investigated in the Mediterranean area. Approximately 700 erosive events and 1.5 years of rainfall energies measured by a rainfall impact measurement device were used to evaluate the effect of the rainfall measurement interval (5 min ⩽ Δ t  ⩽ 60 min) on the erosivity determinations in the Mediterranean semi-arid area of Sicily. According to both literature and practical considerations, a reference time interval equal to 15 min was used in this investigation. Hourly rainfall data led to an appreciable underes…

Mediterranean climateHydrologyStormAtmospheric sciencesMediterranean areaR-value (insulation)USLE/RUSLER-factorsoil erosion; USLE/RUSLE; R-factor; rainfall kinetic energy; Mediterranean areaSoil lossrainfall kinetic energySoil waterMaximum differenceSoil erosionErosionSettore AGR/08 - Idraulica Agraria E Sistemazioni Idraulico-ForestaliMediterranean areaEnvironmental scienceWater Science and TechnologyJournal of Hydrology
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QR-Factorization Algorithm for Computed Tomography (CT): Comparison With FDK and Conjugate Gradient (CG) Algorithms

2018

[EN] Even though QR-factorization of the system matrix for tomographic devices has been already used for medical imaging, to date, no satisfactory solution has been found for solving large linear systems, such as those used in computed tomography (CT) (in the order of 106 equations). In CT, the Feldkamp, Davis, and Kress back projection algorithm (FDK) and iterative methods like conjugate gradient (CG) are the standard methods used for image reconstruction. As the image reconstruction problem can be modeled by a large linear system of equations, QR-factorization of the system matrix could be used to solve this system. Current advances in computer science enable the use of direct methods for…

QR-factorization algorithmComputer scienceIterative methodImage qualityLinear systemDavis and Kress (FDK)Iterative reconstruction3-D images reconstructionSystem of linear equationsAtomic and Molecular Physics and OpticsConjugate gradient (CG)FeldkampQR decompositionMatrix (mathematics)Conjugate gradient methodRadiology Nuclear Medicine and imagingMedical imagingMATEMATICA APLICADAInstrumentationAlgorithmComputed tomography (CT)Reconstruction algorithmsReconstruction toolkit (RTK)
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