Search results for "RACE"
showing 10 items of 4458 documents
Neutrophil extracellular traps arm DC vaccination against NPM-mutant myeloproliferation
2022
Neutrophil extracellular traps (NETs) are web-like chromatin structures composed by dsDNA and histones, decorated with antimicrobial proteins. Their interaction with dendritic cells (DCs) allows DC activation and maturation toward presentation of NET-associated antigens. Differently from other types of cell death that imply protein denaturation, NETosis preserves the proteins localized onto the DNA threads for proper enzymatic activity and conformational status, including immunogenic epitopes. Besides neutrophils, leukemic cells can release extracellular traps displaying leukemia-associated antigens, prototypically mutant nucleophosmin (NPMc+) that upon mutation translocates from nucleolus …
Dalle leggi razziali alla normativa xenofoba: come il diritto inventa la disuguaglianza
2011
Gli studiosi della Critical Race Theory,una corrente statunitense di giuristi riflessivi interessati alla questione razziale, hanno sostenuto che l’essere bianchi o neri non sia tanto una questione di pigmentazione della pelle quanto di leggi. Questa affermazione apparentemente bizzarra ha una sua plausibilità che proverò a spiegare ripercorrendo la storia della costruzione legale del concetto di razza. Inoltrerò cercherò di mostrare come le categorie di "straniero" e "clandestino", nell'attuale diritto italiano, stiano assumendo connotazioni e funzioni analoghe alle vecchia nozione di razza nel diritto segregazionista statunitense.
I tamburi a cornice in Sicilia
2015
Le prime attestazioni della presenza del tamburo a cornice in Sicilia risalgono al V secolo a.C. Lo strumento è poi documentato fino ai giorni nostri attraverso raffigu¬razioni, documenti d’archivio, resoconti di viaggiatori stranieri, testi di interesse folklorico e, piuttosto ampiamente, dalla ricerca etnomusicologica moderna, per mezzo di audio-registrazioni e videofilmati. Morfologia, tecniche esecutive, repertori, decorazioni, contesto d’uso dei tamburelli in Sicilia si inscrivono nel più ampio quadro dell’area italiana (centro-meridionale) e mediterranea, ma con alcune specificità, soprattutto nelle tecniche esecutive. Queste, sebbene affini a quelle impiegate in altre regioni italian…
Giovanni Marrasio fra Virgilio, Orazio e Properzio
2021
Questo saggio mira a presentare la figura e l’opera poetica di Giovanni Marrasio (Noto, 1400/1404 - Caltanissetta, sett. 1452), umanista siciliano autore dell’«Angelinetum» e dei «Carmina varia», attivo nella prima metà del sec. XV fra la Sicilia e Siena, Firenze e Padova, Ferrara e Napoli, in rapporti con altri umanisti e letterati (Giovanni Aurispa, Antonio Beccadelli, Leonardo Bruni, Enea Silvio Piccolomini, Carlo Marsuppini, Maffeo Vegio, Niccolò Niccoli, Guarino Veronese), potenti uomini di stato (Niccolò III d’Este, Alfonso il Magnanimo) e di chiesa (papa Niccolò V). In particolare, la disamina si concentra sulle suggestioni che Virgilio, Orazio e Properzio hanno esercitato sulla poes…
Can the 20 and 60 s All-Out Test Predict the 2000 m Indoor Rowing Performance in Athletes?
2022
Purpose: The purpose of this study was to look for a new, simple, and fast method of assessing and monitoring indoor race performance and to assess the relationship between 20 s, 60 s, and 2000 m indoor rowing performances of youth rowers to evaluate their anaerobic profile.Methods: For three consecutive days, 17 young able-bodied male rowers (15.8 +/- 2.0 years), performed three tests (20 s, 60 s, and 2000 m) on a rowing ergometer. Mean power (W-20, W-60, and W-2000) and 2000 m time (t(2000)) were considered for the analysis. In addition, 14 athletes (15-18 years) performed a 20 s, 60 s, and 2000 m tests and used this as a control group. To define the anaerobic profile of the athletes, W-2…
Trace Codimensions of Algebras and Their Exponential Growth
2022
The trace codimensions give a quantitative description of the identities satisfied by an algebra with trace. Here we study the asymptotic behaviour of the sequence of trace codimensions c tr n(A) and of pure trace codimensions c ptr n (A) of a finite-dimensional algebra A over a field of characteristic zero. We find an upper and lower bound of both codimensions and as a consequence we get that the limits limn→∞ctrn(A)√n and limn→∞cptrn(A) √n always exist and are integers. This result gives a positive answer to a conjecture of Amitsur in this setting. Finally we characterize the varieties of algebras whose exponential growth is bounded by 2
Mediterranean Diet as a tool for achieving successful ageing
2017
Targeted interventions to slow or postpone ageing and to favour an active life expectancy represent the new perspectives in ageing investigation. Some mechanisms that delay or prevent the onset of ageing disabilities and pathologies have been identified. In general, maintaining a healthy lifestyle seems to reduce many risk factors. In particular, eating habits represent the most concrete and low-cost method to address ageing. Of all dietary habits analysed, the Mediterranean diet has received much attention since it has consistently proven its beneficial influence on health and longevity. The Mediterranean diet is characterized by low glycaemic index and low animal protein intake, it is ric…
Healthy eating as a strategy to achieve successful ageing: focus on Mediterranean diet and functional foods.
People want to live longer. To date, it is impossible not to grow older, but it is desirable to get older in good health, avoiding age-related disabilities. To do this, it is necessary to have a healthy lifestyle which can limit the damage caused by the environmental hazards that face us each day. In humans, healthy ageing and longevity are modulated by a fortunate interaction between genetic and environmental factors. Regarding the latter, physical activity and healthy dietary habits are the most important modifiable factors that can affect the maintenance of a healthy ageing phenotype. A feasible diet that reduces the risk of ageing-related diseases, promoting health ageing and longevity,…
Effects of Oleuropein and Hydroxytyrosol on Inflammatory Mediators: Consequences on Inflammaging
2022
Aging is associated with a low-grade, systemic inflammatory state defined as “inflammaging”, ruled by the loss of proper regulation of the immune system leading to the accumulation of pro-inflammatory mediators. Such a condition is closely connected to an increased risk of developing chronic diseases. A number of studies demonstrate that olive oil phenolic compound oleuropein and its derivative hydroxytyrosol contribute to modulating tissue inflammation and oxidative stress, thus becoming attractive potential candidates to be used in the context of nutraceutical interventions, in order to ameliorate systemic inflammation in aging subjects. In this review, we aim to summarize the available d…
Invecchiamento cerebrale, nutraceutici e neuroprotezione
2017
The nervous system requires a high and continuous energy requirement and despite the brain represents only 2% of the body weight it receives about 15% of the cardiac output and consumes 20% of oxygen. The neuronal activity therefore determines a significant increase in energy consumption thus favoring the fact that the brain, during aging, becomes the seat of crucial structural and functional changes that condition the health in a fundamental way.