Search results for "RACE"
showing 10 items of 4458 documents
Comparative analysis of leaf shape development inEschscholzia californicaand other Papaveraceae-Eschscholzioideae
2011
Dissected leaves in Papaveraceae-Eschscholzioideae have an architecture frequently encountered in the basal eudicot clade Ranunculales that could represent an ancestral condition for eudicots. Developmental morphology of foliage leaves was investigated using scanning electron microscopy and focusing on primordium formation activity (primary morphogenesis) at the leaf margin. Eschscholzia californica, E. lobii, and Hunnemannia fumariaefolia had a polyternate-acropetal mode of leaf dissection. Segment formation continued around the whole leaf blade periphery. Differences in mature leaf architecture was traced to variations in regional blastozone activity and duration. Epidermal cell size meas…
GTPases of the Rho Subfamily Are Required for Brucella abortus Internalization in Nonprofessional Phagocytes
2001
Members of the genus Brucella are intracellular -Proteobacteria responsible for brucellosis, a chronic disease of humans and animals. Little is known about Brucella virulence mechanisms, but the abilities of these bacteria to invade and to survive within cells are decisive factors for causing disease. Transmission electron and fluorescence microscopy of infected nonprofessional phagocytic HeLa cells revealed minor membrane changes accompanied by discrete recruitment of F-actin at the site of Brucella abortus entry. Cell uptake of B. abortus was negatively affected to various degrees by actin, actin-myosin, and microtubule chemical inhibitors. Modulators of MAPKs and protein-tyrosine kinases…
MORPHOLOGICAL AND ANATOMICAL STRUCTURE OF GALLS IN GENISTA FLORIDA L. SUBSP. POLYGALIPHYLLA (BROT.) COUTHINO (LEGUMINOSAE)
1999
This paper describes the morphology and anatomy of a structure which appears in the floral racemes of Genista florida L. subsp. polygaliphylla (Brot.) Couthino. In this subspecies the floral racemes have a small number of flowers. This structure develops quite frequently in this taxon, which is found in the northwest of the Iberian Peninsula, but never in Genista florida subsp. florida. Its morphology is simple: bottle-shaped, wide at the base and elongated to a narrow peak at the upper extreme. Anatomical examination shows that these structures have a close similarity to flowers. Since they develop by the oviposition of one insect of the Cecidomyiidae family in the floral buds, they can be…
Antimicrobial and antistaphylococcal biofilm activity from the sea urchin Paracentrotus lividus
2010
Aims: Staphylococcal biofilm-associated infections are resistant to conventional antibiotics. Consequently, new agents are needed to treat them. With this aim, we focused on the effector cells (coelomocytes) of the sea urchin Paracentrotus lividus immune system. Methods and Results: We tested the activity of the 5-kDa peptide fraction of the cytosol from coelomocytes (5-CC) against a group of Gram-positive, Gram-negative bacteria and fungi. We determined minimal inhibitory concentrations (MICs) ranging from 253·7 to 15·8 mg ml−1. We observed an inhibitory activity and antibiofilm properties of 5-CC against staphylococcal biofilms of reference strains Staphylococcus epidermidis DSM 3269 an…
Trophic Transfer of Trace Elements in an Isotopically Constructed Food Chain From a Semi-enclosed Marine Coastal Area (Stagnone di Marsala, Sicily, M…
2012
Trace element accumulation is particularly important in coastal and transitional environments, which act as contaminant buffers between the continental and marine systems. We compared trace element transfer to the biota in two locations with different open-sea exposures in a semi-enclosed marine coastal area (Stagnone di Marsala, Sicily, Italy) using isotopically reconstructed food chains. Samples of sediment, macroalgae, seagrasses, invertebrates, fish, and bird feathers were sampled in July 2006 and analysed for stable carbon and nitrogen isotopes (δ(13)C, δ(15)N) and trace elements (arsenic [As], cadmium [Cd], total mercury [THg], and lead [Pb]). Trophic magnification factors were calcul…
The Impact of Moyamoya Disease and
2019
Moyamoya disease (MMD) is a rare cerebrovascular disorder characterized by occlusion of bilateral internal carotid and intracerebral arteries with the compensatory growth of fragile small vessels. MMD patients develop recurrent infarctions in the basal ganglia and subcortical regions. Symptoms include transient ischemic attack or stroke, seizures, and headaches, which may occur suddenly or in a stepwise progression. Mutations in Ring Finger Protein 213 (RNF213), a Zinc ring finger protein, have been identified in some MMD patients but the etiology of MMD is still largely unknown. To gain insight into the pathophysiology of MMD, we characterized the impact of the RNF213 mutations on plasma p…
Impact of Manaus City on the Amazon Green Ocean atmosphere: Ozone production, precursor sensitivity and aerosol load
2010
As a contribution to the Large-Scale Biosphere-Atmosphere Experiment in Amazonia – Cooperative LBA Airborne Regional Experiment (LBA-CLAIRE-2001) field campaign in the heart of the Amazon Basin, we analyzed the temporal and spatial dynamics of the urban plume of Manaus City during the wet-to-dry season transition period in July 2001. During the flights, we performed vertical stacks of crosswind transects in the urban outflow downwind of Manaus City, measuring a comprehensive set of trace constituents including O3, NO, NO2, CO, VOC, CO2, and H2O. Aerosol loads were characterized by concentrations of total aerosol number (CN) and cloud condensation nuclei (CCN), and by light scattering proper…
Synthetic/ECM-inspired hybrid platform for hollow microcarriers with ROS-triggered nanoporation hallmarks
2017
Reactive oxygen species (ROS) are key pathological signals expressed in inflammatory diseases such as cancer, ischemic conditions and atherosclerosis. An ideal drug delivery system should not only be responsive to these signals but also should not elicit an unfavourable host response. This study presents an innovative platform for drug delivery where a natural/synthetic composite system composed of collagen type I and a synthesized polythioether, ensures a dual stimuli-responsive behaviour. Collagen type I is an extracellular matrix constituent protein, responsive to matrix metalloproteinases (MMP) cleavage per se. Polythioethers are stable synthetic polymers characterized by the presence o…
Application of the moss bag biomonitoring technique in an active volcanic environment (Mt. Etna, Italy).
2011
This paper presents the preliminary results of a biomonitoring study based on the use of moss bags exposed at 24 sites on Etna volcano. Sphagnum mosses were used to study bioaccumulation originating from atmospheric deposition, by measuring the tissue contents of major and a large suite of trace elements. Elements, such as Tl, Bi, As, Se, Cu and Cd, display high concentrations in the exposed samples close to the active vents. This study confirms the effectiveness of the moss bags technique also in active volcanic areas.