Search results for "RAIL"

Experimental Investigation of the Modal Response of a Rail Span during and after Wheel Passage

2020

This paper examines the vibrations of a rail span (rail section between two consecutive sleepers) during and after the passage of a rail car’s wheel as well as under impact hammer excitation. In literature, the dynamic response of railway tracks under moving loads has been studied extensively. Many of these studies focus on the responses in relation to displacement/force-time histories and wave propagation parameters. These responses are investigated for the time instants when rail car wheels transverse over the rail spans of interest. In this context, an investigation of responses in relation to modal parameters during and after moving loads might provide additional information. Such info…

Tomographic Particle Image Velocimetry and Thermography in Rayleigh-Bènard Convection Using Suspended Thermochromic Liquid Crystals and Digital Image…

2003

French railway history in geo-historical perspectives, infrastructure, demographic dynamics and territorial change

2014

International audience

Les traces de la vitesse entre réseau et territoire : approche géohistorique de la croissance du réseau ferroviaire français

2016

The interaction between space and network are frequently questioned in the academic literature, by asking the economical and demographical impacts of a new infrastructure, often studied at the scale of a project. This work aims to investigate the components of the interaction in both large spatial and temporal scales. The hypothesis is that the temporal depth and the national scale could bring new explanations. This work is based on the collect, the exploitation and the analysis of the large spatio-temporal database FRANcE (French Railway Network). It identifies all sections of the network since the 19th century and the population census. This database also contains the traces of the speed,…

Nuove stazioni, periferie e città

2016

L’infrastruttura contemporanea amplia e fa slittare il proprio campo semantico, trasformandosi definitivamente da artefatto tecnico di carattere titanico ed epico ad elemento riparatore dei tessuti urbani, flessibile, trasformabile. In questo quadro in mutazione, numerose esperienze negli ultimi trent’anni hanno affermato in Europa occidentale il ruolo dei grandi progetti ferroviari come vettori di trasformazione urbana. A quindici anni dall’avvio della prima stagione di concorsi internazionali banditi per le nuove stazioni dell’Alta Velocità in Italia, è possibile un bilancio volto non solo al semplice confronto dei risultati direttamente pertinenti la realizzazione e l’esercizio dell’oper…

Mechanical characterisation and 3D fractional viscoelastic modelling of railway sub-ballast rubberised asphalt

The differentiation of the serotonergic neurons in the Drosophila ventral nerve cord depends on the combined function of the zinc finger proteins Eag…

1997

ABSTRACT The Drosophila ventral nerve cord (vNC) derives from a stereotyped population of neural stem cells, neuroblasts (NBs), each of which gives rise to a characteristic cell lineage. The mechanisms leading to the specification and differentiation of these lineages are largely unknown. Here we analyse mechanisms leading to cell differentiation within the NB 7-3 lineage. Analogous to the grasshopper, NB 7-3 is the progenitor of the Drosophila vNC serotonergic neurons. The zinc finger protein Eagle (Eg) is expressed in NB 7-3 just after delamination and is present in all NB 7-3 progeny until late stage 17. DiI cell lineage tracing and immunocytochemistry reveal that eg is required for norm…

SAHA/TRAIL combination induces detachment and anoikis of MDA-MB231 and MCF-7 breast cancer cells

2012

Abstract SAHA, an inhibitor of histone deacetylase activity, has been shown to sensitize tumor cells to apoptosis induced by TRAIL, a member of TNF-family. In this paper we investigated the effect of SAHA/TRAIL combination in two breast cancer cell lines, the ERα−positive MCF-7 and the ERα−negative MDA-MB231. Treatment of MDA-MB231 and MCF-7 cells with SAHA in combination with TRAIL caused detachment of cells followed by anoikis, a form of apoptosis which occurs after cell detachment, while treatment with SAHA or TRAIL alone did not produce these effects. The effects were more evident in MDA-MB231 cells, which were chosen for ascertaining the mechanism of SAHA/TRAIL action. Our results show…

Predicting risk and outcomes for frail older adults: a protocol for an umbrella review of available frailty screening tools

2015

REVIEW QUESTION / OBJECTIVE  The aim of this systematic review is to comprehensively search the available literature and to summarize the best available evidence from systematic reviews in relation to published screening tools to identify pre-frailty and frailty in older adults, that is: (i) to determine their psychometric proprieties; (ii) to assess their capacity to detect pre-frail and frail conditions against established methods; and (iii) to evaluate their predictive ability. More specifically, the review will focus on the following questions: - What is the reliability and validity of existing screening tools that assess pre-frailty/frailty in older patients? - How sensitive and specif…

Ruby paplašinājums ērtai tulkojumu pārvaldei

2017

Kvalifikācijas darbā izstrādātais Ruby paplašinājums Kakimasu (japāņu valodā rakstīt) ir paredzēts ātrai un ērtai projekta tulkojumu pārvaldei. Kakimasu ļauj tulkot projektu no pārlūka, neaiztiekot YAML failus, kuros pēc noklusējuma glabājas tulkojumi, līdz ar to, projektu var iztulkot bez īpašām priekšzināšanām, turklāt ātri, kas ietaupa tik dārgo laiku un līdzekļus. Paplašinājumu var lietot kā izstrādātāji, tā paši klienti. Paplašinājums ir izstrādāts Ruby programmēšanas valodā un tas ir saderīgs ar jebkuru Ruby on Rails 5 projektu. Paplašinājuma izstrādē tika izmantotas arī HTML, CSS, Javascript tehnoloģijas.