Search results for "RAIL"
showing 10 items of 699 documents
Neuroplasticity in the Adjustment to Blindness
1999
Loss of vision due to injury to the eyes results in deafferentation of very large areas of the human cortex and poses striking demands on other sensory systems to adjust to blindness in a society that heavily relies on vision. Blind subjects need to extract crucial spatial information from touch and hearing. To accomplish this, plastic trans-modal changes appear to take place by which a larger area of the sensorimotor cortex is devoted to the representation of the reading finger in Braille readers, and parts of the former visual cortex are recruited for the processing of tactile and auditory information.
Frailty and risk of complications in head and neck oncologic surgery. Systematic review and dose-response meta-analysis
2021
Background There is emerging evidence that frail individuals present a decreased physiological reserve, decreased ability to maintain homeostasis, and increased vulnerability to stressors. The concept of frailty has become increasingly recognized as a valuable measure in oncological surgical patients, including those with head and neck cancer. Preoperative screening for frailty may provide an individualized risk assessment that can be used by an interdisciplinary team for preoperative counseling and to improve outcomes. The aim of this meta-analysis was to evaluate the relationship between frailty and the risk of major postoperative complications in frail individuals submitted to head and n…
Invasive Versus Conservative Strategy in Frail Patients With NSTEMI: The MOSCA-FRAIL Clinical Trial Study Design
2019
Abstract Introduction and objectives Although clinical guidelines recommend invasive management in non–ST-segment elevation myocardial infarction (NSTEMI), this strategy is underused in frail elderly patients in the real world. Furthermore, these patients are underrepresented in clinical trials and therefore the evidence is scarce. Our hypothesis is that an invasive strategy will improve prognosis in elderly frail patients with NSTEMI . Methods This will be a prospective, multicenter, randomized trial, in which the conservative and invasive strategies will be compared in patients meeting all of the following inclusion criteria: NSTEMI diagnosis, age ≥ 70 years, and frailty defined by a cate…
Impact of Age, Multimorbidity and Frailty on the Prescription of Preventive Antiplatelet Therapy in Older Population
2020
Platelet aggregation inhibitors (PAI) have widely proven their efficiency for the prevention of ischemic cardiovascular events. We aimed to describe PAI prescription in an elderly multimorbid population and to determine the factors that influence their prescription, including the impact of age, comorbidities and frailty, evaluated through a comprehensive geriatric assessment. This cross-sectional study included all patients admitted to the acute geriatric department of a university hospital from November 2016 to January 2017. We included 304 consecutive hospitalized patients aged 88.7 ±
Effects of Home-Based Physical Exercise on Days at Home and Cost-Effectiveness in Pre-Frail and Frail Persons: Randomized Controlled Trial.
2021
Objectives: Frailty increases the risks of hospitalization, institutionalization, and death. Our objective was to study the effects of home-based physical exercise on the number of days spent at home among pre frail and frail persons, versus usual care. In addition, utilization and costs of health care and social services, cost-effectiveness, and health-related quality-of-life (HRQoL) were explored. Design: Randomized controlled trial, with year-long supervised exercise for 60 minutes twice a week versus usual care. Follow-up for 24 months after randomization. Setting and Participants: A sample of 299 home-dwelling persons in South Karelia, Finland. Main inclusion criteria: >65 years, meeti…
Angiogenic and/or pro-apoptotic factors are shed from brain cells via extracellular vesicles
2008
We set a three-cell type coculture system in which neurons and astrocytes synergistically induce brain capillary endothelial cells to form a monolayer with permeability properties resembling those of the physiological blood-brain barrier (BBB) (Schiera et al., 2003; Schiera et al., 2005). On the basis of immunofluorescence, scanner electron microscopy and western blot analyses, we also suggested that both astrocytes and neurons in culture shed extracellular vesicles that contain FGF-2 and VEGF, as well as beta1-integrin, a membrane protein that can be considered a marker of shedding (Schiera et al, 2007; Proia et al., 2008). In addition, it was already known that transformed glial cells (ol…
Evaluation de l'impact d'un futur remblai de la ligne à Grande Vitesse Est Européenne sur le risque de gel dans le vignoble de Champagne
2002
In order to evaluate for the vineyard, the additional risk of freezing, which could be generated by a railway embankment of the High Speed Line (TGV «Paris-Strasbourg») a canvas cover of the future embankment (length 480 m, height 3 m maxi) was drawn up in the bottom of a wineyard slope. Measurements of Actinothermal Index (AI) Temperatures, at the height of the bud (at 50 cm of the surface) and measurements of of cold air windslopes, were carried out on a microclimatic scale. We recorded 19 points of measurements, without then with the presence of the canvas cover, for the nights characterized by a radiative cooling (wind £ 2m.s-2, clear sky) during spring 2001. The possible incidence of t…
Kielilähettiläät tuovat tarinoillaan inspiraatiota ja motivaatiota oppitunneille
2019
”Miksi joudun istumaan ruotsin tunneilla?” on kysymys, jonka varmasti kaikki ruotsinopettajat ovat kuulleet ainakin kerran uransa aikana. Opettajilla saattaa mennä iso osa energiasta oppilaidensa motivointiin. Samalla oppilaille voi jäädä epäselväksi, mihin ruotsia oikein tarvitsee elämässä, ja näin ollen oppimistulokset voivat jäädä laihoiksi ruotsin osalta. Muun muassa Ylen teettämä kysely osoittaa, että neljäsosa suomalaisista kokee, että ei osaa ruotsia lainkaan (Jaskari 2019). Tänä vuonna opettajien tueksi on kehitetty Kielilähettiläät (Språkambassadörerna) -toimintaa. Ruotsin kieltä osaava kielilähettiläs vierailee ruotsin tunneilla, ja toiminnan tavoitteena on herättää oppilaiden sis…
Memoria y erosión: la herencia de la revolución espectral y su vigencia actual en la composición
2013
Los compositores Gérard Grisey y Tristan Murail fueron dos de los principales representantes de la corriente compositiva llamada espectral, que se desarrolló en Francia a mediados de los años 70 del siglo XX como reacción a la estética postserial. El presente artículo plantea, a partir de una retrospectiva panorámica de sus principios estéticos y de su actitud hacia la composición musical, una revisión crítica de los postulados de la estética espectral, así como de su permanencia en la música de hoy, atendiendo a su vez a las numerosas transformaciones que ha experimentado, así como a un ámbito de difusión y asimilación que franqueó las fronteras del continente europeo para convertirse en u…
Svētā Grāla mīta elementi – metavēstījuma veidošanas līdzeklis kriptovēstures romānos
2014
Promocijas darbā pētīts individuālos vēstījumos izmantotu Svētā Grāla mīta elementu potenciāls ietekmēt metavēstījumu. Kritiski izvērtēti vēstījuma un metavēstījuma jēdzieni, aplūkotas mīta funkcijas un mīta elementiem piemītošs resakralizācijas potenciāls, sniegts vēsturiskais Svētā Grāla mīta un Romas Katoļu baznīcas vēstījumu attiecību fons. Iezīmētas kriptovēstures romāna kā žanru hibrīda konvencijas. Analizējot kriptovēstures vēstījumus, uzrādīts mitoloģiskās un zinātniskās domāšanas konflikts, atklātas stāstītāju identitātei aktuālākās tēmas un pretestība metavēstījumam. Salīdzināti ārzemju un latviešu kriptovēstures romānu aktantu identitātes reprezentanti. Vienotā sistēmā skatīts in…