Search results for "RAM"

showing 10 items of 35643 documents

Feasibility of a Responsibility-Based Leadership Training Program for Novice Physical Activity Instructors

2021

Most coaches and instructors would like to teach more than just sport skills to their athletes and children. However, to promote athletes' or children's holistic development and teach them to take responsibility and lead, requires the coaches and instructors to first master the skills themselves. Therefore, feasible, high quality leadership training programs where coaches and physical activity instructors are taught to teach and share leadership are needed. The aim of the current study was to evaluate the feasibility of a leadership training program to optimize it and to determine whether to proceed with its evaluation. In the leadership training program, eight Finnish novice physical activ…

AFTER-SCHOOL PROGRAMliikunnanohjaajat515 PsychologySOCIAL-RESPONSIBILITYvastuullisuusIMPLEMENTATION FIDELITYphysical activitykoulutusohjelmatBasic Behavioral and Social ScienceSPORTshared leadershipClinical ResearchBehavioral and Social ScienceADOLESCENTSPsychologyEDUCATION TEACHERSteaching personal and social responsibility modeljohtajuusOriginal Researchpositive youth developmentleadership trainingRANDOMIZATIONSHARED LEADERSHIPMODEL5144 Social psychologyammatillinen kehitys5141 Sociology516 Educational sciencesCognitive Sciencesnovice instructorPOSITIVE YOUTH DEVELOPMENTfeasibility
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An improvement of ComiR algorithm for microRNA target prediction by exploiting coding region sequences of mRNAs

2020

AbstractMicroRNA are small non-coding RNAs that post-transcriptionally regulate the expression levels of messenger RNAs. MicroRNA regulation activity depends on the recognition of binding sites located on mRNA molecules. ComiR is a web tool realized to predict the targets of a set of microRNAs, starting from their expression profile. ComiR was trained with the information regarding binding sites in the 3’utr region, by using a reliable dataset containing the targets of endogenously expressed microRNA in D. melanogaster S2 cells. This dataset was obtained by comparing the results from two different experimental approaches, i.e., inhibition, and immunoprecipitation of the AGO1 protein--a comp…

AGO1ImmunoprecipitationComputer sciencelcsh:Computer applications to medicine. Medical informaticsBiochemistryOpen Reading Frames03 medical and health sciences0302 clinical medicineStructural BiologymicroRNAMelanogasterAnimalsHumansCoding regionGene silencing3'UTRRNA MessengerBinding sitelcsh:QH301-705.5Molecular Biology030304 developmental biology0303 health sciencesMessenger RNAbiologyThree prime untranslated regionResearchApplied MathematicsmicroRNA target predictionbiology.organism_classificationComputer Science Applications3’UTRMicroRNAsDrosophila melanogasterlcsh:Biology (General)Coding regionlcsh:R858-859.7DNA microarrayDrosophila melanogasterAlgorithmAlgorithms030217 neurology & neurosurgeryBMC Bioinformatics
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Calibration of microscopic traffic simulation models for evaluating operation and safety performance at roundabouts

AIMSUN microsimulation roundabout genetic algorithmSSAM surrogate safety measureturbo-roundaboutsingle-lane roundabouts; double-lane roundabouts; turbo-roundabouts; entry capacity; operations; gap- acceptance parameters; Systematic Review; Meta-analysis; capacity uncertainty; AIMSUN microsimulation roundabout genetic algorithm; passenger car equivalent; SSAM surrogate safety measurecapacity uncertaintygap- acceptance parameteroperationsingle-lane roundaboutpassenger car equivalentSettore ICAR/04 - Strade Ferrovie Ed AeroportiMeta-analysiSystematic Reviewdouble-lane roundaboutentry capacity
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Time-Varying mHAP-III Is the Most Accurate Predictor of Survival in Patients with Hepatocellular Carcinoma Undergoing Transarterial Chemoembolization

2021

<b><i>Introduction:</i></b> The prognosis of patients undergoing transarterial chemoembolization (TACE) is extremely variable, and a confounding factor is that TACE is often repeated several times. We retrospectively evaluated the accuracy of different prognostic scores and staging systems in estimating overall survival (OS) in patients with hepatocellular carcinoma (HCC). <b><i>Methods:</i></b> An analysis considering prognostic models as time-varying variables was performed, calculating OS from the time of TACE to the time of the subsequent treatment. Total follow-up time for each patient was therefore split into several observation times ac…

ALBI grade; Barcelona Clinic Liver Cancer; Cancer of the Liver Italian Program; ITALICA staging system; MESIAHmedicine.medical_specialtylcsh:RC254-282GastroenterologyALBI gradeBarcelona Clinic Liver CancerInternal medicineMedicineIn patientCancer of the Liver Italian ProgramITALICA staging systemRadiologic ResponseSettore MED/12 - GastroenterologiaOriginal PaperHepatologybusiness.industryProportional hazards modelConfoundingHazard ratiolcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensmedicine.diseaseMESIAHOncologyHepatocellular carcinomaAkaike information criterionbusinessLiver cancer
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Metabolic signatures across the full spectrum of non-alcoholic fatty liver disease.

2022

Funder: European Commission

ALTtype 2 diabetes mellitusROC receiving operator characteristicaspartate aminotransferaseHSDLDL low-density lipoproteinUHPLC ultrahigh-performance liquid chromatographyROCHCCNon-alcoholic steatohepatitisGCPCANASHGastroenterology2-HB 2-hydroxybutanoic acid; 3-HB 3-hydroxybutanoic acid; ALT alanine aminotransferase; AST aspartate aminotransferase; CE cholesterol ester; Cer ceramide; FFA free fatty acid; FLIP Fatty Liver Inhibition of Progression; Fibrosis; GC gas chromatography; HCC hepatocellular carcinoma; HSD honest significant difference; LC lipid cluster; LDL low-density lipoprotein; LM lipid and metabolite; LMC lipid metabolite and clinical variable; LPC lysophosphatidylcholine; Lipidomics; Mass spectrometry; Metabolomics; NAFL non-alcoholic fatty liver; NAFLD non-alcoholic fatty liver disease; NAS NASH activity score; NASH non-alcoholic steatohepatitis; NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network; NRR non-rejection rate; Non-alcoholic steatohepatitis; PC(O) ether PC; PC phosphatidylcholine; PCA principal component analysis; PE phosphatidylethanolamine; QTOFMS quadrupole-time-of-flight mass spectrometry; ROC receiving operator characteristic; SAF steatosis activity and fibrosis; SM sphingomyelin; T2DM type 2 diabetes mellitus; TG triacylglycerol; UHPLC ultrahigh-performance liquid chromatographySAFSAF steatosis activity and fibrosisLM lipid and metabolitehonest significant differenceHSD honest significant differenceTG triacylglycerolnon-rejection ratecholesterol esterPCPEGC gas chromatographyfree fatty acidFLIPNASH non-alcoholic steatohepatitisNIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkBIOMARKERST2DMPE phosphatidylethanolamineLDLlipidNAFLDFFA free fatty acid2-HBMetabolomicsNAFL non-alcoholic fatty liverLMCphosphatidylcholineScience & TechnologySM sphingomyelinGastroenterology & HepatologyMass spectrometryactivitynutritional and metabolic diseasesT2DM type 2 diabetes mellitusACIDSreceiving operator characteristicdigestive system diseasesquadrupole-time-of-flight mass spectrometryLC lipid clusterlow-density lipoproteinNAS2-HB 2-hydroxybutanoic acidNAS NASH activity scoreQTOFMSether PCNRRSCORING SYSTEMprincipal component analysisgas chromatographyLC2-hydroxybutanoic acidPROGRESSIONAST aspartate aminotransferaseLMPC phosphatidylcholinePC(O)MARKERSUHPLCsteatosisTOOLImmunology and AllergyINSULIN-RESISTANCECerSMFatty Liver Inhibition of Progressionhepatocellular carcinoma2-HB 2-hydroxybutanoic acid NIDDK NASH-CRN National Institute of Digestive Diseases and Kidney NASH Clinical Research Network NRR non-rejection rate Non-alcoholic steatohepatitis PC(O) ether PC PC phosphatidylcholine PCA principal component analysis PE phosphatidylethanolamine QTOFMS quadrupole-time-of-flight mass spectrometry ROC receiving operator characteristic SAF steatosis activity and fibrosis SM T2DM type 2 diabetes mellitus TG triacylglycerol UHPLC ultrahigh-performance liquid chromatographyultrahigh-performance liquid chromatographyCELPC3-HBNAFLnon-alcoholic fatty liverTGtriacylglycerolNRR non-rejection rateLife Sciences & BiomedicineNAFLD non-alcoholic fatty liver diseaseFLIP Fatty Liver Inhibition of Progressionalanine aminotransferasemetaboliteCer ceramideCE cholesterol estersphingomyelinlysophosphatidylcholineand fibrosisALT alanine aminotransferaseInternal MedicineceramideNational Institute of Digestive Diseases and Kidney NASH Clinical Research NetworkAST3-HB 3-hydroxybutanoic acidQTOFMS quadrupole-time-of-flight mass spectrometryPCA principal component analysisLPC lysophosphatidylcholineHepatologynon-alcoholic fatty liver diseaseand clinical variablePC(O) ether PC3-hydroxybutanoic acidFibrosisNASH activity scoreNIDDK NASH-CRNlipid clusterlipid and metabolitephosphatidylethanolamineLipidomicsLMC lipid metabolite and clinical variableFFAHCC hepatocellular carcinomaJHEP reports : innovation in hepatology
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Jaunu apramicīna atvasinājumu sintēze

2022

Jaunu apramicīna atvasinājumu sintēze. Freimanis N., zinātniskais vadītājs Dr. ķīm. Dmitrijs Lubriks. Maģistra darbs, 90 lappuses, 51 attēls, 3 tabulas, 74 literatūras avoti, 14 pielikumi. Latviešu valodā. Maģistra darba literatūras apskata daļā ir aplūkota vispārīga informācija par aminoglikozīdu grupas antibiotiku bioloģiskajām īpašībām, kā arī ir padziļinātāk apskatītas apramicīna bioloģiskās īpašības un modifikācijas iespējas dažādās molekulas pozīcijās. Maģistra darba ietvaros ir izstrādāta un veikta jaunu aminoglikozīdu grupas antibiotiku atvasinājumu sintēze, kā potenciālu medikamentu izveide pret multirezistentajām patogēnām baktērijām, kas balstīti uz apramicīna bāzes un furanozes …

AMINOGLIKOZĪDIANTIBIOTIKASAPRAMICĪNSBAKTĒRIJU REZISTENCEĶīmija
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Ancova metode ar pielietojumu biostatistikā

2019

Šajā darbā tiks apskatīta mūsdienās lielu nozīmi ieguvusī ANCOVA metode, kuru izmanto medicīniskos pētījumos. Īss ieskats tiek aplūkots divām metodēm-ANOVA metodei un lineārajai regresijai,lai saprastu kā ANCOVA metode tika izveidota. Tas ir ļoti nozīmīgi, jo tās veido ANCOVA metodi. Kā arī teorijas beigās apskata ANCOVA metodi. Metodi pielietojot jāpārbauda dažādi nosacījumi, tāpēc tika izveidots algoritms, kas spēj apvienot visas nepieciešamās darbības, kā arī tiek pievienots R programmas kods. Darba nobeigumā tiks apskatīti arī praktiski piemēri, kuri spēs parādīt tās nozīmīgumu reālās dzīves situācijās.

ANCOVAANOVAalgoritmsR programmaMatemātikalineārā regresija
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Lisätty todellisuus vähittäiskaupan markkinointiviestinnässä

2017

Lisätty todellisuus eli AR (englanniksi augmented reality) lisää todellisuuteen virtuaalisen elementin. Vähittäiskaupan markkinointiviestinnässä lisättyä todellisuutta on käytetty useiden vuosien ajan vahvistamaan brändikokemusta. Lisätty todellisuus mahdollistaa mukaansatempaavan markkinoinnin ja lisää asiakkaiden uskollisuutta. Lisättyä todellisuutta voi hyödyntää neljän paradigman kautta, jotka ovat aktiiviset painotuotteet ja pakkaukset, virtuaalipeilit, virtuaali-ikkunat ja paikannusta käyttävät AR-sovellukset. Lisätyn todellisuuden sisältö, käyttäjät, kohdeyleisö, sivulliset ja taustatekijät ovat viisi asiaa, joiden pohjalta suunnitellaan optimaalinen AR-kampanja. Esimerkiksi vaatteid…

AR-selainAR-browsermobiilisovelluksetohjelmistokehysmarketing communicationsoftware frameworklisätty todellisuusmarkkinointiviestintäaugmented reality
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Safety and immunomodulatory effects of three probiotic strains isolated from the feces of breast-fed infants in healthy adults: SETOPROB study.

2013

We previously described the isolation and characterization of three probiotic strains from the feces of exclusively breast-fed newborn infants: Lactobacillus paracasei CNCM I-4034, Bifidobacterium breve CNCM I-4035 and Lactobacillus rhamnosus CNCM I-4036. These strains were shown to adhere to intestinal mucus in vitro, to be sensitive to antibiotics and to resist biliary salts and low pH. In the present study, a multicenter, randomized, double-blind, placebo-controlled trial with 100 healthy volunteers in three Spanish cities was carried out to evaluate the tolerance, safety, gut colonization and immunomodulatory effects of these three probiotics. Volunteers underwent a 15-day washout perio…

ARN Bacterianoved/biology.organism_classification_rank.speciesPhysiologylcsh:Medicine:Phenomena and Processes::Biological Phenomena::Ecological and Environmental Phenomena::Environment::Ecosystem::Biodiversity::Biota::Microbiota [Medical Subject Headings]law.inventionFecesProbioticAntibioticslawLactobacillus:Phenomena and Processes::Physiological Phenomena::Nutritional Physiological Phenomena::Child Nutritional Physiological Phenomena::Infant Nutritional Physiological Phenomena::Breast Feeding [Medical Subject Headings]lcsh:Science:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleic Acids::RNA::RNA Bacterial [Medical Subject Headings]BifidobacteriumMultidisciplinaryBifidobacterium brevebiologyLacticaseibacillus rhamnosusMicrobiotaHibridación in SituInterleukin-10:Organisms::Bacteria::Gram-Positive Bacteria::Lactobacillales::Lactobacillaceae::Lactobacillus [Medical Subject Headings]Breast FeedingBloodCytokinesFemaleResearch ArticleAdult:Anatomy::Fluids and Secretions::Feces [Medical Subject Headings]Lactobacillus paracasei:Organisms::Bacteria::Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Bacteria::Gram-Positive Endospore-Forming Rods::Clostridium::Clostridium difficile [Medical Subject Headings]Microbiology:Chemicals and Drugs::Nucleic Acids Nucleotides and Nucleosides::Nucleic Acids::Nucleic Acid Probes::Oligonucleotide Probes [Medical Subject Headings]Double-Blind MethodLactobacillus rhamnosusHumansImmunologic Factors:Analytical Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Clinical Laboratory Techniques::Cytological Techniques::Histocytological Preparation Techniques::Staining and Labeling::In Situ Hybridization [Medical Subject Headings]FecesSafety studiesved/biologyProbioticslcsh:RClostridium difficile:Organisms::Bacteria::Gram-Positive Bacteria::Actinobacteria::Bifidobacterium [Medical Subject Headings]biology.organism_classificationImmunoglobulin ALactobacilluslcsh:QInterleukin-4BifidobacteriumBreast feedingSondas de OligonucleótidosPLoS ONE
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La Cultura se muere : ¡Vivan las Artes!

2002

ARTESIndustrias de la culturaCondición ciudadanaCulturaManifiesto por la pazCondición cívicaVidal-Beneyto JoséPolíticas culturalesPATRIMONIOPotencia creadoraAsociacionesTriundo de la culturaProgramasGlobalidadAcciones: Acciones de una vida: Cultura y ArtesPublicaciones: Obra periodística: Columnas y artículos de opiniónActivismo benéficoFracasoComercialización culturalFundacionesMundo de las ArtesPobrezaImpulso creador
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