Search results for "RAM"

showing 10 items of 35643 documents

The Effectiveness of EMOVERE: An Emotional Education Program for Young Couples

2021

Our aim was to assess the effectiveness of EMOVERE, a psychoeducational and experiential program to increase emotion regulation in couples. Forty-four young couples (n = 88) aged between 18 and 36 years old participated in the study (53.4% women

AdultCounselingMaleProgram evaluation050103 clinical psychologyemotion regulationAdolescentSexual BehaviorHealth Toxicology and MutagenesisEmotionslcsh:Medicine050109 social psychologyPersonal SatisfactionArticleYoung Adultyoung adulthoodMultivariate analysis of varianceemotional competencesIntervention (counseling)Humans0501 psychology and cognitive sciencesYoung adultinterventionattachmentcouplesEmotional intelligencelcsh:R05 social sciencesMultilevel modelPublic Health Environmental and Occupational Healthprogram evaluationModerationSexual PartnersFemaleAnalysis of variancePsychologyClinical psychologyInternational Journal of Environmental Research and Public Health
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Center differences and cross-national invariance in help-seeking for panic disorder. A report from the cross-national collaborative panic study.

1992

Help-seeking behaviour for treatment of panic disorder was investigated in the sample of the Cross-National Collaborative Panic Study Second Phase. A total of 1168 patients were entered into this trial in 14 countries. Although there were significant center differences in prior treatment and utilization of health services there were also similarities. Treatment had been provided mainly by general practitioners. Drug treatment consisted mostly of prescription of classical tranquilizers and had a longer duration than treatment by psychotherapy. Patients with agoraphobic avoidance, past major depression and longer duration of illness used medical and psychiatric treatment facilities more inten…

AdultCross-Cultural ComparisonMalemedicine.medical_specialtyImipramineHealth (social science)Social PsychologyEpidemiologyPharmacotherapyEpidemiologymedicineHumansMedical prescriptionPsychiatryDepression (differential diagnoses)Alprazolambusiness.industryPanic disorderIncidencePanicPatient Acceptance of Health Caremedicine.diseaseHelp-seekingPsychiatry and Mental healthCross-Sectional StudiesPanic DisorderFemalemedicine.symptombusinessAnxiety disorderClinical psychologySocial psychiatry and psychiatric epidemiology
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Clinical and Microbiologic Effects of Subgingival Controlled-Release Delivery of Chlorhexidine Chip in the Treatment of Periodontitis: A Multicenter …

2008

Background: The main therapeutic approach for periodontal diseases is mechanical treatment of root surfaces via scaling and root planing (SRP). Multicenter clinical trials have demonstrated that the adjunctive use of a chlorhexidine (CHX) chip is effective in improving clinical results compared to SRP alone. However, some recent studies failed to confirm these clinical results, and conflicting results were reported regarding the effects of the CHX chip on subgingival microflora. The aim of this study was to provide further data on the clinical and microbiologic effects of CHX chips when used as an adjunct to SRP. Methods: A total of 116 systemically healthy individuals with moderate to adva…

AdultDNA BacterialMalemedicine.drug_classBleeding on probingColony Count MicrobialDental PlaqueDentistryStatistics Nonparametriclaw.inventionBacteria AnaerobicScaling and root planingAntisepticRandomized controlled triallawChlorhexidine/therapeutic use controlled clinical trial drug delivery system periodontitis/therapymedicineHumansSingle-Blind MethodperiodontitisAgedPeriodontitischlorexidine; periodontitis; periodontitis/therapy; controlled clinical trial; drug delivery systems; chlorhexidine/therapeutic usebusiness.industryChlorhexidineChlorhexidinePeriodontologyMiddle Agedmedicine.diseaseClinical trialDelayed-Action PreparationsMultivariate AnalysisAnti-Infective Agents LocalDental ScalingPeriodonticsFemalePeriodontal Indexmedicine.symptombusinessmedicine.drugJournal of Periodontology
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Recurrent cerebral ischaemia in a pregnant woman with patent foramen ovale II° and thrombophilia.

2014

SummaryThis case report concerns a pregnant multipara (age: 27 years) in the 16th gestational week. She developed a sudden onset of paraesthesia in her left lower arm although injecting dalteparin 5000 IU once daily subcutaneously (s. c.) due to a heterozygous factor V Leiden mutation and a prior miscarriage in the first pregnancy and preeclampsia in her third pregnancy. After the miscarriage she delivered two healthy children under prophylactic anticoagulation with low molecular weight heparin (LMWH). Now via magnetic resonance imaging (MRI) she was diagnosed as having multiple cerebral ischaemic lesions. Further workup revealed the presence of a patent foramen ovale (PFO) II° but no venou…

AdultDalteparinmedicine.medical_specialtymedicine.drug_classInjections SubcutaneousPregnancy Complications CardiovascularLow molecular weight heparinForamen Ovale PatentThrombophiliaPreeclampsiaMiscarriageBrain IschemiaPregnancyRecurrencemedicineHumansThrombophiliaPregnancybusiness.industryPregnancy Complications HematologicAnticoagulantsHematologymedicine.diseaseSurgeryVenous thrombosisTreatment OutcomeAnesthesiaPatent foramen ovaleGestationFemalebusinessHamostaseologie
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Effect of loperamide on jejunal electrolyte and water transport, prostaglandin E 2-induced secretion and intestinal transit time in man

1991

Jejunal perfusion was performed in 12 healthy volunteers to evaluate the dose dependent effects of loperamide on intestinal absorption, stimulated secretion and transit. In 6 volunteers intestinal perfusion of the jejunal segment with isotonic NaCl solution was followed by addition of loperamide in increasing doses (2–8 mg·l−1). The volunteers were pretreated with 1 mg·l−1 prostaglandin E2 (PgE2) in the perfusate before addition of 4 mg·l−1 loperamide. Phenolsulphonphtalein (PSP) boluses (2 ml) were given to measure mean transit time (MTT). Loperamide 2 mg·l−1 converted the minor secretion after perfusion with the standard solution (water −1.45 ml·min−1, Na −0.09 and Cl −0.04 mmol·min−1) to…

AdultDiarrheaMalemedicine.medical_specialtyLoperamideAdolescentAbsorption (skin)LoperamideDinoprostoneIntestinal absorptionJejunumChloridesInternal medicinemedicineHumansPharmacology (medical)Prostaglandin E2Gastrointestinal TransitPharmacologyWater transportDose-Response Relationship DrugChemistrySodiumBiological TransportGeneral MedicineWater-Electrolyte BalanceJejunumEndocrinologymedicine.anatomical_structureIntestinal AbsorptionMechanism of actionmedicine.symptomPerfusionmedicine.drugEuropean Journal of Clinical Pharmacology
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Influence of Senna, Fibre, and Fibre + Senna on Colonic Transit in Loperamide-induced Constipation

1993

Retarded colonic transit and disturbed defecation are the most prominent pathophysiological mechanisms in constipation. Both may be influenced by bulking agents and by laxatives such as senna. Direct measurements of the influence of such substances on colonic transit are rare mainly because of technical problems. We measured gastric emptying, small and large intestinal transit in 24 healthy volunteers by a newly developed method employing a metal detector. Twelve persons taking a normal diet received loperamide in a dose sufficient to double the individual transit time. All subjects measured gastrointestinal transit time under normal conditions and with Sennatin containing purified sennosid…

AdultDietary FiberMalemedicine.medical_specialtyLoperamideConstipationAdolescentSennaCassiaLoperamideGastroenterologyFecesCassiaInternal medicinemedicineHumansGastrointestinal TransitFecesPharmacologyPlants Medicinalbiologybusiness.industrySenna Extractdigestive oral and skin physiologyGeneral Medicinebiology.organism_classificationIntestinesDrug CombinationsGastric EmptyingDefecationFemaleDietary fibermedicine.symptombusinessConstipationmedicine.drugPharmacology
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Radiation dose distribution in functional heart regions from tangential breast cancer radiotherapy

2015

Abstract Background and purpose To analyze the distribution of individually-determined radiation dose to the heart and its functional sub-structures after radiotherapy in breast cancer patients treated in Germany during 1998–2008. Material and methods We obtained electronic treatment planning records for 769 female breast cancer patients treated with megavoltage tangential field radiotherapy. All dose distributions were re-calculated using Eclipse with the anisotropic analytical algorithm (AAA) for photon fields, and the electron Monte Carlo algorithm for electron boost fields. Based on individual dose volume histograms for the complete heart and several functional sub-structures, we estima…

AdultDose-volume histogrammedicine.medical_treatmentBreast Neoplasms030218 nuclear medicine & medical imaging03 medical and health sciencesQuadrant (abdomen)0302 clinical medicineBreast cancerHumansMedicineDosimetryRadiology Nuclear Medicine and imagingBreastRadiation treatment planningAgedbusiness.industryRadiotherapy Planning Computer-AssistedHeartRadiotherapy DosageHematologyMiddle Agedmedicine.diseaseRadiation therapyOncologyParasternal line030220 oncology & carcinogenesisFemalebusinessNuclear medicineMonte Carlo MethodBody mass indexRadiotherapy and Oncology
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Quantitative methylation analysis of developmentally important genes in human pregnancy losses after ART and spontaneous conception.

2009

To study possible effects of assisted reproductive technologies (ART) on epigenetic reprogramming, we have analyzed the DNA methylation levels of differentially methylated regions (DMRs) of seven imprinted genes (H19, MEG3, LIT1, MEST, NESP55, PEG3 and SNRPN) as well as the promoter regions of the pluripotency gene NANOG and the tumor suppressor gene APC in chorionic villus samples (CVS) of 42 spontaneous miscarriages and stillbirths after ART and 29 abortions/stillbirths after spontaneous conception. We did not find an increased rate of faulty methylation patterns after ART, but significant and trend differences (ROC curve analysis, Wilcoxon test) in the methylation levels of LIT1 (P = 0.0…

AdultEmbryologyGenes APCReproductive Techniques AssistedKruppel-Like Transcription FactorsGestational AgeReproductive technologyBiologyRisk AssessmentYoung AdultPregnancyRisk FactorsGermanyGeneticsHumansGenetic Predisposition to DiseaseEpigeneticsIsraelMolecular BiologyGeneticsRegulation of gene expressionMosaicismObstetrics and GynecologyGene Expression Regulation DevelopmentalCell BiologyMethylationDNA MethylationMiddle AgedStillbirthAbortion SpontaneousDifferentially methylated regionsPhenotypeReproductive MedicineDNA methylationLinear ModelsFemaleGenomic imprintingReprogrammingDevelopmental BiologyMaternal AgeMolecular human reproduction
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Can novel early non-invasive biomarkers of embryo quality be identified with time-lapse imaging to predict live birth?

2019

AbstractSTUDY QUESTIONCan time-lapse imaging systems make it possible to identify novel early non-invasive biomarkers to predict live birth?SUMMARY ANSWERFrom mostly high-grade embryos, out of 35 morphometric, morphologic and morphokinetic variables, only pronuclei (PN) position at time of PN juxtaposition and the absence of multinucleated blastomeres at the 2-cell stage (MNB2cell), were potentially associated with live birth.WHAT IS KNOWN ALREADYPrevious studies indicate that some kinetic markers may be predictive of blastocyst development and embryonic implantation. Certain teams have suggested including some of them in decisional algorithms for embryo transfers.STUDY DESIGN, SIZE, DURATI…

AdultEmbryologymedicine.medical_specialtyPregnancy RatePopulationEmbryonic DevelopmentFertilization in VitroLogistic regressionICSITime-Lapse Imaginglive birthOddsembryo morphologyEmbryo Culture Techniques03 medical and health sciences0302 clinical medicinePregnancymedicineHumansembryo kineticsBlastocysteducationRetrospective Studies030304 developmental biology0303 health scienceseducation.field_of_study030219 obstetrics & reproductive medicinePronucleusObstetricsbusiness.industryRehabilitationembryo morphometric parametersObstetrics and GynecologyEmbryoEmbryo TransferBlastocystmedicine.anatomical_structureReproductive Medicinetime-lapse imaging systemOriginal ArticleFemalebusinessLive birthBiomarkersEmbryo qualityHuman Reproduction
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Carbohydrate-deficient transferrin (CDT) and HDL cholesterol (HDL) are highly correlated in male alcohol dependent patients.

2000

Background: Serum levels of total HDL cholesterol (HDL) are reportedly influenced by recent alcohol intake. We examined the correlation between HDL cholesterol and widely used markers of excessive alcohol intake, such as carbohydrate-deficient transferrin (CDT), γ-glutamyl-transferase (GGT), or mean corpuscular volume of erythrocytes (MCV), of which CDT is thought to be the most specific. Methods: Several serological markers [i.e., CDT, GGT, aspartate aminotransferase (ASAT), alanine aminotransferase (ALAT), MCV, and HDL] were determined in 100 actively drinking male patients with alcohol dependence (DSM-IV) and in 27 non-alcohol-dependent controls, according to routine procedures. Spearman…

AdultErythrocyte IndicesMalemedicine.medical_specialtyAdolescentCarbohydrate deficient transferrinMedicine (miscellaneous)AlcoholToxicologyStatistics Nonparametricchemistry.chemical_compoundInternal medicinemedicineHumansMean corpuscular volumeAgedchemistry.chemical_classificationEthanolmedicine.diagnostic_testbusiness.industryCholesterolAlcohol dependenceCholesterol HDLTransferringamma-GlutamyltransferaseMiddle AgedPsychiatry and Mental healthAlcoholismEndocrinologychemistryTransferrinToxicitylipids (amino acids peptides and proteins)businessBiomarkersAlcoholism, clinical and experimental research
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