Search results for "RAM"

Retrospective Analysis of Whole-Body Magnetic Resonance Imaging of Bone Manifestations in Long-Term Treated Patients with Gaucher Disease Type 1

2018

We retrospectively assessed bone and visceral manifestations in patients with Gaucher disease type 1 (GD1) with whole-body magnetic resonance imaging (WB-MRI) to determine the effects of different timing in initiating long-term enzyme replacement therapy.In 17 patients with GD1, we performed 2 WB-MRI examinations at a median interval of 13 months. Patients had received enzyme replacement therapy with alglucerase/imiglucerase for a median of 13 years prior to the first examination. MRI results were retrospectively stratified based on treatment initiation into 2 groups: "early" (age ≤12 years, median 5 years) and "late" (during adulthood, median 32 years). We evaluated occurrence of irreversi…

Pharmacotherapy of panic attacks.

1988

Phosphodiesterase-4 inhibition improves corticosteroid insensitivity in pulmonary endothelial cells under oxidative stress.

2012

Several clinical studies have shown that smoking in asthmatics and chronic obstructive pulmonary disease patients is closely associated with corticosteroid refractoriness. In this work, we have analyzed glucocorticoid insensitivity in human pulmonary artery endothelial cells (HPAECs) under cigarette smoke extract (CSE) exposure as well as the possible additive effects of the combination therapy with a phosphodiesterase (PDE)-4 inhibitor. Interleukin (IL)-8 was measured in cell supernatants by ELISA. Histone deacetylase (HDAC), histone acetylase (HAT), and intracellular cAMP levels were measured by colorimetric assays and enzyme immunoassay, respectively. PDE4 isotypes and glucocorticoid rec…

Validity of an inertial system for measuring velocity, force, and power during hamstring exercises performed on a flywheel resistance training device

2020

Background Inertial hamstring exercises promote functional changes leading to lower rates of hamstring injuries. However, variable training measurement systems have not been specifically validated for hamstring exercises. Accordingly, this study aimed to evaluate the validity of the Inertial Measurement System (IMS) to measure the velocity, force, and power during the performance of different hamstring exercises on a flywheel resistance training device. Methods Fifteen males (average age: 22.4 ± 2.5 years; body mass: 77.3 ± 9.8 kg; height: 179.5 ± 7.4 cm; weekly physical activity: 434.0 ± 169.2 min; years of strength training: 4.3 ± 2.2 years) performed the bilateral stiff-leg deadlift (SD…

Canal transportation caused by a new instrumentation technique and three standard techniques

1996

The ability of three different enlarging techniques (balanced force concept, step-back, and recapitulation) and a prototype system to maintain the original canal path during root canal preparation were compared, in vitro, with a theoretical ideally prepared root canal. Measurements were made at the concave and convex sides of the canal at four different levels (1, 4, 5, and 7 mm from apical, respectively). Simulated root canals embedded in clear casting resin and an enlarging computer-supported device were used for this study. The results showed that none of the enlarging techniques used in this study was able to prepare a canal ideally. The prototype system, at level 1, showed an ideal amo…

Four-subtest short-form of the WAIS-IV for assessment of patients diagnosed with schizophrenia.

2021

Abstract Introduction The present study aimed to obtain a short form of the Spanish version of the WAIS-IV for patients diagnosed with schizophrenia that requires about half an hour to be administered. The reduced test can be very useful in clinical and research settings when an estimation of the intelligence quotient (IQ) is required to decide about intervention programs or to describe the sample. Materials and methods A sample of 143 patients participated in the study, 91 out of them were the test group, and the other 52 were used for a cross-validation analysis. To increase the content validity, the decision was made to create a short form composed of a subtest of each of the four cognit…

El consumo abusivo de alcohol en inmigrantes latinoamericanos que participan en programas de intervención para maltratadores: importancia de la adher…

2016

En este estudio se analizan las tasas de abandono del tratamiento en hombres inmigrantes latinoamericanos con problemas de consumo de alcohol (PCA) derivados a programas de intervención con maltratadores y se explora si aquellos que consiguen finalizar la intervención se diferencian de los que no tienen PCA en variables resultado de la intervención. La muestra la componen 107 hombres latinoamericanos condenados por violencia contra la mujer. Al contrario de lo esperado, no se confirman mayores tasas de abandono entre los participantes con PCA. Independientemente de tener o no PCA, los participantes que finalizaron el programa mostraron mejoría en todas las variables objetivo de la intervenc…

Improvement of knowledge and postural habits after an educational intervention program in school students

2019

To study the effect of an educational intervention programme concerning knowledge and postural habits for back health on a group of 10 to 11-year-old students. Two groups of 5th grade primary school students were selected. A control group (CG) (n=16), and an experimental group (EG) (n=16) who developed a back-health educational programme. A follow-up was carried out one month after the end of the intervention. The proposed educational intervention improved the results of both the knowledge and postural habits of the participants. The increase in the level of knowledge concerning health and back care in the daily lives of the EG (x̅=6.32) was significantly greater than that observed in the C…

Development of Learning Needs - Grounded Pedagogical Intervention Program for Adults with Social Anxiety Disorders

2015

The cognitive behavior therapy is one of the most widely used and is considered as the most effective method of treating social anxiety. However there are some researches drawing attention to the necessity to create new, effective methods of intervention for solving of problems caused by social anxiety. For the present moment there are made various researches concerning the different aspects of the disorders caused by the social anxiety within the fields of psychology and psychosomatic medicine, but there are almost no researches within the context of social anxiety in the field of pedagogy. Therefore there is lack of pedagogical solutions for the support of people having the disorders caus…

Intra-operative locally injected pharmacotherapy as a novel strategy for adhesion prophylaxis.

2012

Abstract Background Pharmacotherapy for peritoneal adhesion prophylaxis has been a focus for intensive research. Previous strategies included intravenous and intraperitoneal application of suitable pharmaceutical agents. However, success of these strategies in humans has been limited. Here we describe intra-operative local injection of pharmaceuticals as a novel strategy for adhesion prophylaxis. Methods N  = 208 peritoneal lesions were created in 26 adult Wistar rats. In each animal, lesions on one flank were randomly chosen for treatment with locally injected prednisolone whereas the contralateral side was injected with normal saline. Half of the animals were randomly selected for early a…