Search results for "RANSAC"

Transformational Leadership in the Local Police in Spain: a Leader-Follower Distance Approach

2014

AbstractBased on the transformational leadership theory (Bass, 1985), the aim of the present study was to analyze the differences in leadership styles according to the various leading ranks and the organizational follower-leader distance reported by a representative sample of 975 local police members (828 male and 147 female) from Valencian Community (Spain). Results showed differences by rank (p< .01), and by rank distance (p< .05). The general intendents showed the most optimal profile of leadership in all the variables examined (transformational-leadership behaviors, transactional-leadership behaviors,laissez-fairebehaviors, satisfaction with the leader, extra effort by follower, a…

Motives and Agency in Forced Marriage among the Urban Poor in Tanzania

2020

Using the method of third-person elicitation and 171 interviews in Dar es Salaam, Tanzania, I examine one form of forced marriage, ‘marriage on the mat’ (ndoa ya mkeka). In it, girls’ parents use the normative pressure of Islamic norms to circumvent the groom’s lack of consent to the marriage and promote their daughter’s future economic security. Premarital sex and forced marriage, rarely examined together, are often causally linked and provide strong motives for parents to resort to ndoa ya mkeka. In an urban context where girls’ and women’s income-earning possibilities are limited to transactional sex, marriage at a young age is often the only way to embody the culturally approved behavio…

La agricultura a tiempo parcial y la externalización de servicios agrarios como vehículo del cambio estructural

2010

El «ajuste clásico» ha sido interpretado frecuentemente como la senda racional y óptima de modernización del sector agrario. Esto ha llevado a considerar a la agricultura a tiempo parcial como un subproducto (ineficiente) del modelo clásico. Frente a este planteamiento, el artículo defiende la potencial contribución de la agricultura a tiempo parcial (y la externalización de servicios asociada a la misma) al proceso de innovación y de modernización de las estructuras agrarias. Se revisa críticamente la literatura adoptando una perspectiva microeconómica y territorial y esbozando un marco analítico que combina los enfoques de los costes de transacción y evolucionista. Utilizando información …

Activation of c-Jun N-terminal kinase 1 by UV irradiation is inhibited by wortmannin without affecting c-iun expression.

1999

Activation of c-Jun N-terminal kinases (JNKs)/stress-activated protein kinases is an early response of cells upon exposure to DNA-damaging agents. JNK-mediated phosphorylation of c-Jun is currently understood to stimulate the transactivating potency of AP-1 (e.g., c-Jun/c-Fos; c-Jun/ATF-2), thereby increasing the expression of AP-1 target genes. Here we show that stimulation of JNK1 activity is not a general early response of cells exposed to genotoxic agents. Treatment of NIH 3T3 cells with UV light (UV-C) as well as with methyl methanesulfonate (MMS) caused activation of JNK1 and an increase in c-Jun protein and AP-1 binding activity, whereas antineoplastic drugs such as mafosfamide, mito…

Glycogen synthase 2 is a novel target gene of peroxisome proliferator-activated receptors.

2007

International audience; Glycogen synthase 2 (Gys-2) is the ratelimiting enzyme in the storage of glycogen in liver and adipose tissue, yet little is known about regulation of Gys-2 transcription. The peroxisome proliferator-activated receptors (PPARs) are transcription factors involved in the regulation of lipid and glucose metabolism and might be hypothesized to govern glycogen synthesis as well. Here, we show that Gys-2 is a direct target gene of PPARalpha, PPARbeta/delta and PPARgamma. Expression of Gys-2 is significantly reduced in adipose tissue of PPARalpha-/-, PPARbeta/delta-/- and PPARgamma+/- mice. Furthermore, synthetic PPARbeta/delta, and gamma agonists markedly up-regulate Gys-2…

Polycerasoidol, a Natural Prenylated Benzopyran with a Dual PPARα/PPARγ Agonist Activity and Anti-inflammatory Effect

2019

Dual peroxisome proliferator-activated receptor-α/γ (PPARα/γ) agonists regulate both lipid and glucose homeostasis under different metabolic conditions and can exert anti-inflammatory activity. We investigated the potential dual PPARα/γ agonism of prenylated benzopyrans polycerasoidol (1) and polycerasoidin (2) and their derivatives for novel drug development. Nine semisynthetic derivatives were prepared from the natural polycerasoidol (1) and polycerasoidin (2), which were evaluated for PPARα, -γ, -δ and retinoid X receptor-α activity in transactivation assays. Polycerasoidol (1) exhibited potent dual PPARα/γ agonism and low cytotoxicity. Structure–activity relationship studies revealed th…

2019

Using the method of third-person elicitation and 171 interviews in Dar es Salaam, Tanzania, I examine one form of forced marriage, ‘marriage on the mat’ (ndoa ya mkeka). In it, girls’ parents use t...

The Peroxisomal 3-keto-acyl-CoA thiolase B Gene Expression Is under the Dual Control of PPARα and HNF4α in the Liver

2011

PPARα and HNF4α are nuclear receptors that control gene transcription by direct binding to specific nucleotide sequences. Using transgenic mice deficient for either PPARα or HNF4α, we show that the expression of the peroxisomal3-keto-acyl-CoA thiolase B(Thb) is under the dependence of these two transcription factors. Transactivation and gel shift experiments identified a novel PPAR response element within intron 3 of theThbgene, by which PPARα but not HNF4α transactivates. Intriguingly, we found that HNF4α enhanced PPARα/RXRα transactivation from TB PPRE3 in a DNA-binding independent manner. Coimmunoprecipitation assays supported the hypothesis that HNF4α was physically interacting with RXR…

3D Matrix-Based Visualization System of Association Rules

2017

With the growing number of mining datasets, it becomes increasingly difficult to explore interesting rules because of the large number of resultant and its nature complexity. Studies on human perception and intuition show that graphical representation could be a better illustration of how to seek information from the data using the capabilities of human visual system. In this work, we present and implement a 3D matrix-based approach visualization system of association rules. The main visual representation applies the extended matrix-based approach with rule-to-items mapping to general transaction data set. A novel method merging rules and assigning weight is proposed in order to reduce the …

The moderator role of followers’ personality traits in the relations between leadership styles, two types of task performance and work result satisfa…

2014

Authentic leadership is changing our understanding of what makes good leadership. However, few studies have explored how followers’ individual differences and the nature of the task they perform affect its relation to followers’ work outcomes. We examine the moderator role of two core task types (intellective vs. generative) and two personality traits (conscientiousness and emotional stability) in the relationship between two leadership feedback styles (authentic vs. transactional) and task performance or work result satisfaction in a two-wave experiment. The sample consisted of 228 participants enrolled in an organizational psychology course, 34% of whom had work experience. Our results sh…