Search results for "RAPA"

showing 10 items of 471 documents

A new species of Cypris (Crustacea: Ostracoda) from the Iberian Peninsula and the Balearic Islands, with comments on the first ostracod named using t…

2020

19 páginas, 9 figuras, 3 tablas.

0106 biological sciencesMaleCyprisArthropodaOstracoda010607 zoologyZoologyIdentification keyDistribution010603 evolutionary biology01 natural sciencesCyprididaeGenusOstracodCrustaceaAnimalsAnimaliaCarapaceEcology Evolution Behavior and SystematicsTaxonomybiologySetaBiodiversitybiology.organism_classificationCrustaceanNew speciesEuropeType speciesPodocopidaSpainKey (lock)Integrative taxonomyAnimal Science and ZoologyIdentification key
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Analysis of movement patterns and macrohabitat use in Hermann’s tortoises (Testudo hermanni hermanni, Gmelin 1789) reintroduced in a coastal area dom…

2016

The Hermann’s tortoise is a strictly European species found mostly in areas with Mediterranean and sub-Mediterranean climes and, especially the subspecies T. hermanni hermanni, has to deal with various threats which reduced its geographic distribution to only a few isolated populations. Thus, with the objective of recovering natural populations of the species, numerous reintroduction projects are being carried out throughout its historical and prehistorical geographic distribution. The aim of our study is to evaluate the success of the T. hermanni reintroduction project carried out in the Albufera de Valencia Natural Park since 2011, through the analysis of movements, home range sizes and h…

0106 biological sciencesMediterranean climateIn situ conservationTortoiseTestudo hermanniEcology010604 marine biology & hydrobiologyHome rangeBiologySubspeciesbiology.organism_classification010603 evolutionary biology01 natural sciencesHabitatAnimal Science and ZoologyCarapaceEcology Evolution Behavior and SystematicsAmphibia-Reptilia
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Growth parameters and population structure of Aristeus antennatus (Decapoda, Penaeidae) in the south Tyrrhenian Sea (southern coast of Italy).

2011

Abstract The blue and red shrimp Aristeus antennatus (Risso, 1816) is one of the most important fishery resources in the Mediterranean Sea. Monthly samplings of blue and red shrimp from June 2006 to May 2007 were landed by the trawl fleet in two northwest Sicilian fishing harbours (San Vito Lo Capo and Terrasini). The carapace length (CL) frequency distribution of females ranged between 15.00 and 59.00 mm, whereas male CLs ranged between 17.00 and 34.00 mm. The estimated parameters of the Von Bertalanffy growth function (VBGF) for San Vito lo Capo females and males were: CL∞ = 65 mm, K = 0.58 y–1 and CL∞ = 41 mm, K = 0.71 y–1, respectively; while for Terrasini females and males these were:…

0106 biological sciencesPenaeidaebiologyDecapoda010604 marine biology & hydrobiologyFishingSettore BIO/05 - ZoologiaAquatic Sciencebiology.organism_classification010603 evolutionary biology01 natural sciencesMediterranean BasinShrimpFisheryCarcinologyMediterranean seaPOPULATION STRUCTURE ARISTEUS ANTENNATUSAnimal Science and ZoologySOUTH TYRRHENIAN SEA.14. Life underwaterCarapaceGROWTH PARAMETERSGROWTH PARAMETERS; POPULATION STRUCTURE ARISTEUS ANTENNATUS; SOUTH TYRRHENIAN SEA.
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Like night and day: Reversals of thermal gradients across ghost crab burrows and their implications for thermal ecology

2018

Abstract Ghost crabs, Ocypode cordimanus, inhabit relatively hostile environments subject to thermal fluctuations, including both diurnal and seasonal cycles. For many ectotherms, including ghost crabs, a major challenge is to remain cool during hot daytime temperatures. This can be achieved by adopting a fossorial lifestyle, taking advantage of thermal refuge afforded by burrows of sufficient depth. Another consideration, often overlooked, is the potential advantage associated with ready access to a thermal energy source (a “charging station”) when surface temperatures are cooler. Being able to rapidly elevate body temperature during cool periods would enhance the crab's ability to maintai…

0106 biological sciencesbiologybusiness.industry010604 marine biology & hydrobiologyThermal fluctuationsAquatic ScienceOceanographybiology.organism_classificationAtmospheric sciencesBurrow010603 evolutionary biology01 natural sciencesHeat fluxOcypode cordimanusBurrows Carapace chemistry Ecology Ghost crab Temperature ThermalDiurnal cycleEctothermEnvironmental scienceGhost crabbusinessThermal energy
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Attraction of Trichogramma Wasps to Butterfly Oviposition-Induced Plant Volatiles Depends on Brassica Species, Wasp Strain and Leaf Necrosis

2021

Within the Brassicaceae, wild as well as crop species are challenged by specialist herbivores including cabbage white butterflies (Pieris spp.). The wild crucifer Brassica nigra responds to oviposition by Pieris butterflies by the synergistic expression of two egg-killing traits. Genotypes that express a hypersensitive response (HR)-like necrosis (direct egg-killing) also emit oviposition-induced plant volatiles (OIPVs) attracting Trichogramma egg parasitoids (indirect egg-killing). This so-called double defense line can result in high butterfly egg mortalities. It remains unknown whether this strategy is unique to B. nigra or more common in Brassica species. To test this, we examined the r…

0106 biological scienceshypersensitive responseEvolutionBrassicaTrichogramma evanescens010603 evolutionary biology01 natural sciencesParasitoidBrassica rapaBotanyQH359-425Laboratory of EntomologyQH540-549.5Ecology Evolution Behavior and SystematicsEcologybiologyegg parasitoidshost locationtritrophic interactionsfungifood and beveragesPierisbiology.organism_classificationPE&RCLaboratorium voor EntomologieAttractionBiosystematiekPlant BreedingPieris (butterfly)egg parasitoidBrassica oleraceaBiosystematicsindirect defensePieriTrichogramma010606 plant biology & botanyFrontiers in Ecology and Evolution
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Comments on "Dental lessons from past to present: Ultrastructure and composition of teeth from plesiosaurs, dinosaurs, extinct and recent sharks" by …

2016

The paper mentioned in the title suggests that several groups of extinct vertebrates used fluoroapatite as a tooth mineral in dentine and enamel when alive; its authors posit that this tooth mineralization drastically changed in all these lineages at some point during their evolution, leading to the use of hydroxyapatite as an alternative primary tooth mineral, because of hitherto unconsidered environmental changes. These conclusions are based on their finding high fluoride levels (i.e. fluoroapatite) in the dentine of fossilised shark teeth as well as in both the dentine and enamel of plesiosaurs, mosasaurs, and dinosaurs, which is in sharp contrast to recent teeth (which contain almost no…

0301 basic medicine010506 paleontologyEnamel paintGeneral Chemical EngineeringFluorapatiteZoologyGeneral ChemistryHigh fluoride01 natural sciences03 medical and health scienceschemistry.chemical_compoundstomatognathic diseases030104 developmental biologyTooth mineralizationmedicine.anatomical_structurechemistrystomatognathic systemvisual_artUltrastructurevisual_art.visual_art_mediumDentinmedicinePrimary ToothFluoride0105 earth and related environmental sciences
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Epimagnolin A, a tetrahydrofurofuranoid lignan from Magnolia fargesii, reverses ABCB1-mediated drug resistance.

2018

Abstract Background Epimagnolin A is an ingredient of the Chinese crude drug Shin-i, derived from the dried flower buds of Magnolia fargesii and Magnolia flos, which has been traditionally used for the treatment of allergic rhinitis and nasal congestion, empyema, and sinusitis. The pharmacokinetic activity of epimagnolin A remains to be evaluated. Purpose In this study, we examined the possible interactions of epimagnolin A with human ATP-binding cassette (ABC) transporter ABCB1, a membrane protein vital in regulating the pharmacokinetics of drugs and xenobiotics. Study design/methods The interaction of epimagnolin A with ABCB1 was evaluated in calcein, ATPase, and MTT assays by using Flp-I…

0301 basic medicineATP Binding Cassette Transporter Subfamily BATPasePharmaceutical ScienceATP-binding cassette transporterPharmacologyCrude drugLignans03 medical and health scienceschemistry.chemical_compound0302 clinical medicinePharmacokineticsCell Line TumorDrug DiscoverymedicineHumansEnzyme kineticsP-glycoproteinPharmacologyAdenosine TriphosphatasesbiologyAntineoplastic Agents PhytogenicDrug Resistance MultipleCalceinMolecular Docking Simulation030104 developmental biologyComplementary and alternative medicinechemistryVerapamilDrug Resistance NeoplasmMagnolia030220 oncology & carcinogenesisbiology.proteinMolecular MedicineVerapamilmedicine.drugPhytomedicine : international journal of phytotherapy and phytopharmacology
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Aerobic Exercise and Pharmacological Treatments Counteract Cachexia by Modulating Autophagy in Colon Cancer

2016

Recent studies have correlated physical activity with a better prognosis in cachectic patients, although the underlying mechanisms are not yet understood. In order to identify the pathways involved in the physical activity-mediated rescue of skeletal muscle mass and function, we investigated the effects of voluntary exercise on cachexia in colon carcinoma (C26)-bearing mice. Voluntary exercise prevented loss of muscle mass and function, ultimately increasing survival of C26-bearing mice. We found that the autophagic flux is overloaded in skeletal muscle of both colon carcinoma murine models and patients, but not in running C26-bearing mice, thus suggesting that exercise may release the auto…

0301 basic medicineCachexiaColorectal cancerMuscle Fibers SkeletalMicevoluntary physical activityChloroquineMice Inbred BALB CMultidisciplinaryMuscle WeaknessMyogenesis3. Good healthmedicine.anatomical_structureColonic NeoplasmsFemalecancer cachexiamedicine.drugmedicine.medical_specialty[SDV.CAN]Life Sciences [q-bio]/Cancerautophagic fluxBiologyArticleCachexia03 medical and health sciencesAtrophyInternal medicineCell Line TumorPhysical Conditioning AnimalmedicineAutophagyAerobic exerciseAnimalsHumansMuscle SkeletalSirolimusrapamycinAutophagyAutophagosomesSkeletal musclemuscle wasting[SDV.MHEP.HEG]Life Sciences [q-bio]/Human health and pathology/Hépatology and GastroenterologyRibonucleotidesmedicine.diseaseAminoimidazole CarboxamideSurvival Analysisexercise mimetics030104 developmental biologyEndocrinology5-amino-1-beta-D-ribofuranosyl-imidazole-4-carboxamide (AICAR)LysosomesNeoplasm Transplantationmuscle wasting; cancer cachexia; voluntary physical activity; exercise mimetics; 5-amino-1-beta-D-ribofuranosyl-imidazole-4-carboxamide (AICAR); rapamycin; autophagic flux
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Regulation of GSK-3 activity by curcumin, berberine and resveratrol: Potential effects on multiple diseases.

2017

Natural products or nutraceuticals promote anti-aging, anti-cancer and other health-enhancing effects. A key target of the effects of natural products may be the regulation of the PI3K/PTEN/Akt/mTORC1/GSK-3 pathway. This review will focus on the effects of curcumin (CUR), berberine (BBR) and resveratrol (RES), on the PI3K/PTEN/Akt/mTORC1/GSK-3 pathway, with a special focus on GSK-3. These natural products may regulate the pathway by multiple mechanisms including: reactive oxygen species (ROS), cytokine receptors, mirco-RNAs (miRs) and many others. CUR is present the root of turmeric (Curcuma longa). CUR is used in the treatment of many disorders, especially in those involving inflammatory p…

0301 basic medicineCancer ResearchCurcuminBerberinemTORC1PharmacologyResveratrolMechanistic Target of Rapamycin Complex 1Protective AgentsNatural product03 medical and health scienceschemistry.chemical_compoundGlycogen Synthase Kinase 3Phosphatidylinositol 3-KinasesBerberineGeneticNeoplasmsOsteoarthritisStilbenesGeneticsPTENHumansCurcumaMolecular BiologyProtein kinase BPI3K/AKT/mTOR pathwayInflammationNatural productsbiologyBerberine; Curcumin; Natural products; ResveratrolPTEN PhosphohydrolaseNeurodegenerative Diseasesbiology.organism_classification030104 developmental biologyBiochemistrychemistryGene Expression RegulationCardiovascular DiseasesResveratrolbiology.proteinCurcuminMolecular MedicineProto-Oncogene Proteins c-aktSignal Transduction
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Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidati…

2019

Oxidative stress and a disturbed cellular protein homeostasis (proteostasis) belong to the most important hallmarks of aging and of neurodegenerative disorders. The proteasomal and autophagic-lysosomal degradation pathways are key measures to maintain proteostasis. Here, we report that hippocampal cells selected for full adaptation and resistance to oxidative stress induced by hydrogen peroxide (oxidative stress-resistant cells, OxSR cells) showed a massive increase in the expression of components of the cellular autophagic-lysosomal network and a significantly higher overall autophagic activity. A comparative expression analysis revealed that distinct key regulators of autophagy are upregu…

0301 basic medicineClinical BiochemistryLFQ Label-free quantificationLETM Leucine zipper and EF-hand containing transmembrane proteinmedicine.disease_causeBiochemistryCHX Cycloheximide0302 clinical medicineBNIP3 Bcl-2 interacting protein 3RAPA RapamycinPIK3C3 Class III PI3‐kinasePhosphorylationlcsh:QH301-705.5Neuronslcsh:R5-920PolyUB PolyubiquitinChemistryBAG3OPA1 Optic atrophy 1TOR Serine-Threonine KinasesWIPI1 WD repeat domain phosphoinositide-interacting protein 1ATG Autophagy relatedTFEB Transcription factor EBCell biologyMitochondriasiRNA Small interfering RNADLP1 Dynamin-like protein 1LAMP1 Lysosomal‐associated membrane protein 1PURO Puromycinlcsh:Medicine (General)Protein homeostasisResearch PaperBafA1 Bafilomycin A1LAMP2 Lysosomal‐associated membrane protein 2Proteasome Endopeptidase ComplexRAB18 Member RAS oncogeneTUB TubulinLC3 Light chain 3 proteinOxidative phosphorylationBAG3CTSD Cathepsin DModels BiologicalCell Line03 medical and health sciencesDownregulation and upregulationMacroautophagymedicineAutophagyHumansAdaptationBAG1 Bcl-2-associated athanogene 1BECN1 Beclin1PI3K/AKT/mTOR pathwayAdaptor Proteins Signal TransducingTEM Transmission electron microscopyHsp70 Heat shock protein 70Organic ChemistryAutophagyAutophagosomesmTOR Mammalian target of rapamycinHsp70Oxidative Stress030104 developmental biologyProteostasislcsh:Biology (General)CV CanavanineBAG3 Bcl-2-associated athanogene 3MTT (3-(45-Dimethylthiazol-2-yl)-25-Diphenyltetrazolium Bromide)Apoptosis Regulatory ProteinsLysosomes030217 neurology & neurosurgeryOxidative stressRedox Biology
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