Search results for "RAPA"

ALBERGO A TRAPANI. ARCH. VITO M. CORTE

2012

illustrazione di una realizzazione alberghiera come progetto di riuso di immobili preesistenti, nel centro storico di Trapani.

Uso degli stent medicati con rapamicina in pazienti con situazioni anatomiche o cliniche che favoriscono la restenosi: risultati del follow-up di 6 m…

2004

Dati del follow-up di 6 mesi sui primi 100 pazienti con stent medicati con rapamicina, con situazioni anatomiche e cliniche favorenti la restenosi

2004

Risultati del follow-up di 6 mesi in 100 pazienti con stent medicato con rapamicina rispetto ad altri 100 con stent tradizionale

2004

USE OF THE DRUG ELUTING STENTS WITH RAPAMICIN IN PATIENTS WITH ANATOMICAL OR CLINICAL PATTERNS FAVOURING RESTENOSIS: RESULTS OF A 6-MONTHS FOLLOW-UP …

2004

A Particular Focus on the Prevalence of α- and β-Thalassemia in Western Sicilian Population from Trapani Province in the COVID-19 Era

2023

Thalassemia is a Mendelian inherited blood disease caused by α- and β-globin gene mutations, known as one of the major health problems of Mediterranean populations. Here, we examined the distribution of α- and β-globin gene defects in the Trapani province population. A total of 2,401 individuals from Trapani province were enrolled from January 2007 to December 2021, and routine methodologies were used for detecting the α- and β-globin genic variants. Appropriate analysis was also performed. Eight mutations in the α globin gene showed the highest frequency in the sample studied; three of these genetic variants represented the 94% of the total α-th…

MTOR inhibitor-based combination therapies for pancreatic cancer

2018

Background: Although the mechanistic target of rapamycin (MTOR) kinase, included in the mTORC1 and mTORC2 signalling hubs, has been demonstrated to be active in a significant fraction of patients with pancreatic ductal adenocarcinoma (PDAC), the value of the kinase as a therapeutic target needs further clarification. Methods: We used Mtor floxed mice to analyse the function of the kinase in context of the pancreas at the genetic level. Using a dual-recombinase system, which is based on the flippase-FRT (Flp-FRT) and Cre-loxP recombination technologies, we generated a novel cellular model, allowing the genetic analysis of MTOR functions in tumour maintenance. Cross-species validation and pha…

Il Risorto

2009

scheda sulla sagoma in legno raffigurante il Risorto di Trapani

The controversial role of actors in Italian and Sicilian waterfront areas management and planning

2013

The paper investigates the relationship between planning tools and formal/informal subjects involved in Sicilian waterfront areas management and it focuses on the relation between port plans and other (local and regional) planning instruments and policies. This relationship is explored through an examination of some results of The “Waterfront” project (Water And Territorial policiEs for integRation oF multisectoRial develOpmeNT), developed under the PO 2007-2013 Italia-Malta, that aimed to explore the field of “waterfront” in a different sense from the simple concept of urban or peri-urban coastal areas. The waterfront, in the Project approach, takes a wider identity that refers to the comp…

Trapani: from the Renewal of the Waterfront to the Regeneration of the City

2013

The waterfrornt pf the city of Trapani interlaces a close relationship with the historical centre: with a width of the 921.000 mq, the harbour is in direct contact with the ancient city This closeness makes the waterfront particulary appealing due to the archicterual features of the city, Likewise, the sea remains visible and accessible from several urban areas. The waterfront is characterised by important portal infrastructures, favourable climate conditions and windiness, and a mutual seacity crsstalk. For these reason, in 2005 Trapani was proposed as hosting city for the international sailing event Louis Vuitton Act 8 & 9 of the America's Cup. The decisivie factor that led to this ch…