Search results for "RAPA"

TMS activation of interhemispheric pathways between the posterior parietal cortex and the contralateral motor cortex

2016

Using a twin coil transcranial magnetic stimulation (tc-TMS) approach we have previously demonstrated that facilitation may be detected in the primary motor cortex (M1) following stimulation over the ipsilateral caudal intraparietal sulcus (cIPS). Here we tested the interhemispheric interactions between the IPS and the contralateral motor cortex (M1). We found that conditioning the right cIPS facilitated contralateral M1 when the conditioning stimulus had an intensity of 90% resting motor threshold (RMT) but not at 70% or 110% RMT. Facilitation was maximal when the interstimulus interval (ISI) between cIPS and M1 was 6 or 12 ms. These facilitatory effects were mediated by interactions with …

Autologous Iliac Bone Graft Compared with Biphasic Hydroxyapatite and Calcium Sulfate Cement for the Treatment of Bone Defects in Tibial Plateau Frac…

2019

Background Bone-graft substitutes are commonly used for the augmentation of traumatic bone defects in tibial plateau fractures. However, their clinical performance compared with that of autologous bone-grafting, the gold standard in bone defect reconstruction, still remains under debate. This study investigates the differences in quality of life, pain, and radiographic outcomes in the treatment of tibial plateau fracture-associated bone defects with either autologous bone grafts or a bioresorbable hydroxyapatite and calcium sulfate cement (CERAMENT BONE VOID FILLER [CBVF]; BONESUPPORT). Methods In this study, 135 patients with acute depression and split-depression fractures of the proximal …

Evidence of noncentrosymmetry of human tooth hydroxyapatite crystals

2014

Herein, we investigate human single hydroxyapatite crystals (enamel and dentine) by convergent-beam electron diffraction (CBED) and automated electron-diffraction tomography (ADT). The CBED pattern shows the absence of the mirror plane perpendicular to the c axis leading to the P63 space group instead of the P63 /m space group considered for larger-scale crystals, this is confirmed by ADT. This experimental evidence is of prime importance for understanding the morphogenesis and the architectural organization of calcified tissues.

Clinical evaluation of nanocrystalline hydroxyapatite paste in the treatment of human periodontal bony defects--a randomized controlled clinical tria…

2008

The aim of this study was to compare the clinical outcome of intrabony periodontal defects following treatment with a novel nanocrystalline hydroxyapatite (NHA) paste to open flap debridement.Twenty-eight subjects, each displaying one intrabony defect with probing depth (PD)or =6 mm and radiographic evidence of an intraosseous componentor =3 mm participated in the present study. Subjects were allocated randomly to treatment with NHA paste (test group) or open flap debridement (control group). At baseline and at 6 months after surgery, the following clinical parameters were recorded by a masked examiner: plaque index, gingival index, PD, clinical attachment level (CAL), and gingival recessio…

Effects of drug therapy on cardiac arrhythmias and ischemia in hypertensives with LVH.

2001

Left ventricular hypertrophy (LVH) in hypertensive subjects is associated with an increased prevalence of ventricular arrhythmias. To evaluate the effect of antihypertensive treatment on cardiac arrhythmias (CA) and transient episodes of myocardial ischemia (TEMI), we studied 46 hypertensive patients with LVH, divided into four groups randomly treated with enalapril, hydrochlorothiazide (HCTZ), atenolol, or verapamil (SR-V) for 6 months. Office blood pressure and office heart rate values were recorded, in basal conditions, after 1 and 6 months of treatment, and all patients underwent echocardiography, electrocardiographic Holter monitoring, and stress testing. All drugs significantly lowere…

Nanocrystalline Hydroxyapatite-Based Material Already Contributes to Implant Stability After 3 Months: A Clinical and Radiologic 3-Year Follow-up Inv…

2014

The present study reports on a 3-year clinical and radiologic follow-up investigation of dental implants placed 3 and 6 months after sinus augmentation in 14 patients. Augmentation was performed with a synthetic bone substitute material composed of nanocrystalline hydroxyapatite. The aim of the study was to determine how the integration period of the bone substitute material, that is, 3 months or 6 months, influences implant integration within the patient's upper jaw. Therefore, the following clinical and radiologic parameters were investigated: implant being in situ; Periotest value; and presence of peri-implant osteolysis, bleeding on probing, plaque, and soft tissue recession around the …

Voltor negre, Buitre negro (VER0000126)

Altres noms vulgars: Cinereous Vulture (Anglès), Vautour moine (Francès), Mönchsgeier (Alemany) Gabinet de Vertebrats (Departament de Zoologia), Facultat de Ciències Biològiques (Campus de Burjassot), C/ Doctor Moliner, s/n, Bloque B. 5é plant, Burjassot (Valencia). Armari: 6-2 La Albufera Hembra Adulto

Impaired parietal magnitude processing in developmental dyscalculia

2007

Summary Developmental dyscalculia (DD) is a specific learning disability affecting the acquisition of school-level mathematical abilities in the context of otherwise normal academic achievement, with prevalence estimates in the order of 3–6% [1] . Behavioural studies show deficits in elementary numerical processing among individuals with pure DD [2,3], indicating that deficits in higher-level mathematical skills may stem from impaired representation and processing of basic numerical magnitude. Adult neuropsychological and neuroimaging research points to the intraparietal sulcus as a key region for the representation and processing of numerical magnitude [4]. This raises the possibility of a…

IL CANTIERE DEL COMPLESSO CARMELITANO DELL’ANNUNZIATA A TRAPANI NELLA SECONDA METÀ DEL CINQUECENTO

2016

Il complesso carmelitano dell’Annunziata a Trapani, costituito dalla chiesa e dal convento annesso (oggi sede del Museo Regionale Agostino Pepoli), appare come un’architettura fortemente stratificata, frutto di una lunga e complessa vicenda progettuale che si snoda dal XIV secolo fino alla metà del Settecento. Il presente studio intende contribuire alla conoscenza del cantiere dell’Annunziata nella seconda metà del Cinquecento, un periodo ancora poco indagato dalle ricerche finora condotte sulla fabbrica, offrendo in particolare alcune riflessioni sui maestri impegnati nella costruzione del complesso architettonico, a partire dall’esame della documentazione relativa alla gestione amministra…

Antimicrobial activity of biogenically produced spherical Se-nanomaterials embedded in organic material against Pseudomonas aeruginosa and Staphyloco…

2017

In an effort to prevent the formation of pathogenic biofilms on hydroxyapatite (HA)-based clinical devices and surfaces, we present a study evaluating the antimicrobial efficacy of Spherical biogenic Se-Nanostructures Embedded in Organic material (Bio Se-NEMO-S) produced by Bacillus mycoides SelTE01 in comparison with two different chemical selenium nanoparticle (SeNP) classes. These nanomaterials have been studied as potential antimicrobials for eradication of established HA-grown biofilms, for preventing biofilm formation on HA-coated surfaces and for inhibition of planktonic cell growth of Pseudomonas aeruginosa NCTC 12934 and Staphylococcus aureus ATCC 25923. Bio Se-NEMO resulted more e…