Search results for "RAV"
showing 10 items of 5866 documents
Quantum gravity with THESEUS
2021
AbstractIn this paper we explore the possibility to search for a dispersion law for light propagation in vacuo with a sample of Gamma-Ray Bursts detected by the THESEUS satellite. Within Quantum Gravity theories, different models for space-time quantization predict relative discrepancies of the speed of photons w.r.t. the speed of light that (in a series expansion) depend on a given power of the ratio of the photon energy to the Planck energy. This ratio is as small as 10− 23 for photons in the soft γ −ray band (100 keV). The dominant effect is determined by the first significant term of this expansion. If the first order in this expansion is relevant, these theories imply a Lorentz Invaria…
The HERMES-Technologic and Scientific Pathfinder
2020
HERMES-TP/SP (High Energy Rapid Modular Ensemble of Satellites Technologic and Scientific Pathfinder) is a constellation of six 3U nano-satellites hosting simple but innovative X-ray detectors, characterized by a large energy band and excellent temporal resolution, and thus optimized for the monitoring of Cosmic High Energy transients such as Gamma Ray Bursts and the electromagnetic counterparts of Gravitational Wave Events, and for the determination of their positions. The projects are funded by the Italian Ministry of University and Research and by the Italian Space Agency, and by the European Union Horizon 2020 Research and Innovation Program under Grant Agreement No. 821896. HERMES-TP/S…
La durée du travail, la norme et ses usages en 1848
2011
Le decret du 2 mars 1848, qui reduit la duree du travail d’une heure, introduit une rupture majeure en instaurant pour la premiere fois une norme nationale fixant une duree maximale pour le travail des adultes. Cette decision souvent citee mais rarement etudiee suscita de multiples debats dans des arenes diverses, au Parlement, dans la presse comme dans les ateliers. L’objectif de cet article est de montrer comment cette decision prise dans le contexte d’effervescence revolutionnaire crea les conditions d’une irreversibilite de l’intervention de l’Etat dans le champ social.
Ingvar the Far-Travelled: between the Byzantium and Caucasus. A Maritime Approach to Discussion
2019
The Journey to the East of the Viking Ingvar the Far-Traveled is one of the events that fit into the history of medieval relations of the Scandinavians with the world of Byzantium. It was a fateful expedition taking place between 1036 and 1041, and to this day it is a source of many controversies and speculations of researchers. The findings of the present paper suggest that the journey did not necessarily proceed to the lands of the Saracens or Byzantium but may have been part of the game played by Constantinople with its ally Tmutarkan, which opposed Jaroslav the Wise, these events unfolding in the north-eastern waters of the Black Sea.
Between the Darkness of Barbarism and the Light of Civilization: British Images of the Finn in the Late Eighteenth Century
2014
This article aims to show that it was the British travellers (Coxe, Tooke, Clarke,et al.) to Finland in the late eighteenth century who discovered Finland for theBritish reading public. As they distinguished the Finns as a separate ‘race’ fromthe Russians, the Swedes, and the Lapps, they contributed to the proto-racialistimage of them that would become popular in the nineteenth century. BecauseSweden had become an important maritime trading partner (in iron ore, tar, andtimber) to the British, its eastern part, Finland, also became an interesting countryto visit en route from Stockholm to Saint Petersburg (or from Saint Petersburgto Stockholm). The travellers were astonished to realize that…
Pero Tafur and Bertradon de la Broquière in Constantinople: The Ceremonial Image of Mary of Trabzond and the Diplomatic Meetings around the Council o…
2019
After the fall of Constantinople (1453), Pero Tafur and Bertrandon de La Broquière make known their works, which are two of the most important travel books written in Europe during the fifteenth century. Both travellers had known, between fifteen and twenty years before, the emperor of Greece, John VIII Palaiologos, Pope Eugene IV and other protagonists of the councils of Basel (1431-1434) and Ferrara-Florence (1438-1439), which decreed the union between the Roman and Greek churches. The travellers were, thus, witnesses, but also informants and active diplomats for the attempts of religious and political union, which Pope Pius II tried to revive after the fall of Constantinople. Tafur and L…
Interacting effects of simulated eutrophication, temperature increase, and microplastic exposure on Daphnia
2020
The effects of multiple stressors are difficult to separate in field studies, and their interactions may be hard to predict if studied in isolation. We studied the effects of decreasing food quality (increase in cyanobacteria from 5 to 95% simulating eutrophication), temperature increase (by 3 °C), and microplastic exposure (1% of the diet) on survival, size, reproduction, and fatty acid composition of the model freshwater cladoceran Daphnia magna. We found that food quality was the major driver of Daphnia responses. When the amount of cyanobacteria increased from 5 to 95% of the diet, there was a drastic decrease in Daphnia survival (from 81 ± 15% to 24 ± 21%), juvenile size (from 1.8 ± 0.…
Liver Fat, Adipose Tissue, and Body Composition Changes After Switching from a Protease Inhibitor or Efavirenz to Raltegravir.
2021
Integrase inhibitors appear to increase body weight, but paradoxically some data indicate that raltegravir (RAL) may decrease liver fat. Our objective was to study the effects of switching from a protease inhibitor (PI) or efavirenz (EFV) to RAL on liver fat, body composition, and metabolic parameters among people living with HIV (PLWH) with high risk for nonalcoholic fatty liver disease (NAFLD). We randomized overweight PLWH with signs of metabolic syndrome to switch a PI or EFV to RAL (
Cytochrome c is released in a single step during apoptosis
2005
Release of cytochrome c from mitochondria is a central event in apoptotic signaling. In this study, we utilized a cytochrome c fusion that binds fluorescent biarsenical ligands (cytochrome c-4CYS (cyt. c-4CYS)) as well as cytochrome c-green fluorescent protein (cyt. c-GFP) to measure its release from mitochondria in different cell types during apoptosis. In single cells, the kinetics of cyt. c-4CYS release was indistinguishable from that of cyt. c-GFP in apoptotic cells expressing both molecules. Lowering the temperature by 7 degrees C did not affect this corelease, but further separated cytochrome c release from the subsequent decrease in mitochondrial membrane potential (DeltaPsi(m)). Cyt…
Immunosurveillance of lung melanoma metastasis in EBI-3-deficient mice mediated by CD8+ T cells.
2008
Abstract EBV-induced gene 3 (EBI-3) codes for a soluble type I receptor homologous to the p40 subunit of IL-12 that is expressed by APCs following activation. In this study, we assessed the role of EBI-3 in a model of lung melanoma metastasis. Intravenous injection of the B16-F10 cell line resulted in a significant reduction of lung tumor metastasis in EBI-3−/− recipient mice compared with wild-type mice. The immunological finding accompanying this effect was the expansion of a newly described cell subset called IFN-γ producing killer dendritic cells associated with CD8+ T cell responses in the lung of EBI-3−/− mice including IFN-γ release and TNF-α-induced programmed tumor cell death. Depl…