Search results for "RAV"

showing 10 items of 5866 documents

A Comparative Study of General Intelligence in Spanish and Moroccan Samples

2012

The aim of this study is to fill a gap in intelligence research by presenting data for the average IQ in Morocco and for a comparable sample in Spain. Adult samples were administered theRaven Standard Progressive Matrices (SPM)(Raven, Court, & Raven, 2001) and scored for the total test and for the three sub-factors of gestalt continuation, verbal-analytical reasoning and visuospatial ability identified by Lynn, Allik, and Irwing (2004). The total test and the three factors have shown satisfactory reliability. Our results for the Moroccan sample show significant relationship between general intelligence factor, gestalt continuation and visuospatial ability with education level and income…

AdultIntelligence TestsMaleLinguistics and LanguageAdolescentIntelligence quotientIntelligenceSample (statistics)Middle AgedVisuospatial abilityLanguage and LinguisticsTest (assessment)MoroccoRaven's Progressive MatricesSocioeconomic FactorsSpainEducational StatusHumansGestalt psychologyFemalePsychologyGeneral PsychologyAgedClinical psychologyThe Spanish journal of psychology
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Does Endovascular Treatment with Curative Intention Have Benefits for Treating High-Grade Arteriovenous Malformation versus Radiosurgery? Efficacy, S…

2021

Background The treatment of high-grade arteriovenous malformations (AVMs) remains challenging. Microsurgery provides a rapid and complete occlusion compared with other options but is associated with undesirable morbidity and mortality. The aim of this study was to compare the occlusion rates, incidence of unfavorable outcomes, and cost-effectiveness of embolization and stereotactic radiosurgery (SRS) as a curative treatment for high-grade AVMs. Methods A retrospective series of 57 consecutive patients with high-grade AVM treated with embolization or SRS, with the aim of achieving complete occlusion, was analyzed. Demographic, clinical, and angioarchitectonic variables were collected. Both t…

AdultIntracranial Arteriovenous MalformationsMalemedicine.medical_specialtyAdolescentmedicine.medical_treatmentCost-Benefit AnalysisLower riskRadiosurgeryRadiosurgeryArteriovenous malformationEmbolization03 medical and health sciencesYoung Adult0302 clinical medicineSeizuresparasitic diseasesOcclusionSpetzler-Martin ScalemedicineHumansEmbolizationChildAgedCerebral Intraventricular HemorrhageAged 80 and overEndovascularbusiness.industryIncidence (epidemiology)Endovascular ProceduresArteriovenous malformationCost-effectiveness analysisMicrosurgeryMiddle Agedmedicine.diseaseSurgeryTreatment Outcome030220 oncology & carcinogenesisChild PreschoolStereotacticSurgeryFemaleNeurology (clinical)businessIntracranial Hemorrhages030217 neurology & neurosurgeryWorld neurosurgery
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Raltegravir Pharmacokinetics in Patients on Asunaprevir-Daclatasvir.

2015

ABSTRACT Raltegravir pharmacokinetics was studied in 20 patients included in the ANRS HC30 QUADRIH Study before and after addition of anti-hepatitis C virus (anti-HCV) quadritherapy, including pegylated-interferon–ribavirin and asunaprevir plus daclatasvir. Raltegravir pharmacokinetic parameters remained unchanged whether administered on or off anti-HCV therapy. In addition, concentrations of raltegravir, asunaprevir, and daclatasvir were not affected by liver cirrhosis. These data suggest that in human immunodeficiency virus (HIV)-HCV-coinfected patients, whether cirrhotic or not, asunaprevir and daclatasvir could be administered safely with raltegravir.

AdultLiver CirrhosisMaleDaclatasvirPyrrolidinesAlpha interferonHIV InfectionsHepacivirusPharmacologyAntiviral AgentsRaltegravir PotassiumPolyethylene Glycolschemistry.chemical_compoundPharmacokineticsRaltegravir PotassiumRibavirinMedicineHumansPharmacology (medical)PharmacologySulfonamidesbusiness.industryCoinfectionRibavirinImidazolesvirus diseasesInterferon-alphaValineHepatitis CHepatitis C ChronicMiddle AgedRaltegravirmedicine.diseaseIsoquinolinesdigestive system diseasesRecombinant ProteinsInfectious DiseaseschemistryLiverHIV-1AsunaprevirDrug Therapy CombinationFemaleCarbamatesbusinessmedicine.drugAntimicrobial agents and chemotherapy
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B-Lines for the assessment of extravascular lung water: Just focused or semi-quantitative?

2020

BACKGROUND B-lines as typical artefacts of lung ultrasound are considered as surrogate measurement for extravascular lung water. However, B-lines develop in the sub-pleural space and do not allow assessment of the whole lung. Here, we present data from the first observational multi-centre study focusing on the correlation between a B-lines score and extravascular lung water in critically ill patients suffering from a variety of diseases. PATIENTS AND METHODS In 184 adult patients, 443 measurements were obtained. B-lines were counted and expressed in a score which was compared to extravascular lung water, measured by single-indicator transpulmonary thermodilution. Appropriate correlation coe…

AdultLung DiseasesMalemedicine.medical_specialtyOxygenation indexCritical IllnessThermodilutionSensitivity and Specificity03 medical and health sciencesYoung Adult0302 clinical medicineInternal medicinemedicineHumans030212 general & internal medicineProspective StudiesLungAgedUltrasonographyAged 80 and overLungReceiver operating characteristicCritically illbusiness.industry030208 emergency & critical care medicineGeneral MedicineOxygenationMiddle Agedrespiratory tract diseasesLung ultrasoundAnesthesiology and Pain MedicineLung watermedicine.anatomical_structureExtravascular Lung WaterCardiologyFemalebusinessSemi quantitativeActa anaesthesiologica ScandinavicaREFERENCES
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Personality and eating habits revisited: Associations between the big five, food choices, and Body Mass Index in a representative Australian sample

2019

Abstract Objective Personality traits are related to health and health-related behavior such as eating habits. However, results are inconsistent regarding exactly which traits are related to eating habits. The eating habits assessed across studies are also not easily comparable, as they are based on different food items and on different computational methods. This study investigated eating habits and their relationship to both the Big Five personality traits and Body Mass Index (BMI; an objective criterion of health status) in a representative Australian sample. Method Participants were 13,892 adults from the Household, Income and Labour Dynamics in Australia survey. An analysis of 14 food …

AdultMale0301 basic medicineAgreeablenessMeatAdolescentPersonality InventoryHealth Statusmedia_common.quotation_subjectEmotionsHealth Behavior030209 endocrinology & metabolismDiet SurveysBody Mass IndexFood PreferencesYoung Adult03 medical and health sciences0302 clinical medicineFood choiceOpenness to experienceHumansPersonalityLongitudinal StudiesBig Five personality traitsGeneral PsychologyAgedmedia_commonAged 80 and over030109 nutrition & dieteticsNutrition and DieteticsExtraversion and introversionDiet Vegetariandigestive oral and skin physiologyAustraliaConscientiousnessMiddle AgedDietRegression AnalysisFemaleFactor Analysis StatisticalPsychologyBody mass indexPersonalityDemographyAppetite
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Personality and meat consumption: The importance of differentiating between type of meat

2018

Recent research has shown that sociodemographic factors and the Big Five personality traits are related to people's overall level of meat consumption. However, there are important differences among various types of meat (e.g., red meat, poultry, and fish) that might lead to differential patterns in how the consumption of specific types of meat is associated with personality and sociodemographic factors. To disentangle these general and specific relationships, we conducted two studies using two large-scale representative samples from different countries: Germany (N = 13,062) and Australia (N = 15,036). Mostly consistent with our expectations, personality and sociodemographic variables showed…

AdultMale0301 basic medicineMeatmedia_common.quotation_subject050109 social psychologyBiologyPoultryYoung Adult03 medical and health sciencesGermanyEnvironmental healthOpenness to experienceAnimalsHumansPersonality0501 psychology and cognitive sciencesBig Five personality traitsGeneral PsychologyAgedmedia_commonAged 80 and overConsumption (economics)030109 nutrition & dieteticsNutrition and DieteticsExtraversion and introversion05 social sciencesMultilevel modelAustraliafood and beveragesMiddle AgedDietRed MeatSeafoodRed Meat ConsumptionRed meatEducational StatusFemalePersonalityAppetite
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A constitutive BCL2 down-regulation aggravates the phenotype of PKD1-mutant-induced polycystic kidney disease

2017

IF 5.340; International audience; The main identified function of BCL2 protein is to prevent cell death by apoptosis. Mice knock-out for Bcl2 demonstrate growth retardation, severe polycystic kidney disease (PKD), gray hair and lymphopenia, and die prematurely after birth. Here, we report a 40-year-old male referred to for abdominal and thoracic aortic dissection with associated aortic root aneurysm, PKD, lymphocytopenia with a history of T cell lymphoblastic lymphoma, white hair since the age of 20, and learning difficulties. PKD, which was also detected in the father and sister, was related to an inherited PKD1 mutation. The combination of PKD with gray hair and lymphocytopenia was also r…

AdultMale0301 basic medicineTRPP Cation Channelsphenotypebcl2 geneBiologymicro rnaMice03 medical and health sciencesdown-regulationsymptom aggravating factorshemic and lymphatic diseasest-lymphocyteGene expressionGeneticsmedicinePolycystic kidney diseaseAnimalsHumansGenetic Predisposition to Disease[ SDV.GEN.GH ] Life Sciences [q-bio]/Genetics/Human geneticsgenesMolecular BiologyGeneGenetics (clinical)Exome sequencingMice KnockoutPKD1apoptosisExonsGeneral MedicinePolycystic Kidney Autosomal Dominantmedicine.diseasePhenotypePedigreeUp-Regulation3. Good healthMicroRNAs030104 developmental biologyMRNA SequencingProto-Oncogene Proteins c-bcl-2[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human geneticsImmunologyCancer researchLymphocytopeniapolycystic kidney diseasesbcl-2 proteinHuman Molecular Genetics
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Direction-dependent activation of the insular cortex during vertical and horizontal hand movements

2016

International audience; The planning of any motor action requires a complex multisensory processing by the brain. Gravity - immutable on Earth - has been shown to be a key input to these mechanisms. Seminal fMRI studies performed during visual perception of falling objects and self-motion demonstrated that humans represent the action of gravity in parts of the cortical vestibular system; in particular, the insular cortex and the cerebellum. However, little is known as to whether a specific neural network is engaged when processing non-visual signals relevant to gravity. We asked participants to perform vertical and horizontal hand movements without visual control, while lying in a 3T-MRI sc…

AdultMale0301 basic medicineVisual perceptiongenetic structuresHorizontal and verticalMovementSocio-culturalefMRI; Gravitational force; Hand movements; Insular cortex; Internal model; Neuroscience (all)gravity-fieldMotor Activityarm movementsInsular cortexBrain mappingVisual controlpositron-emission-tomographyYoung Adult03 medical and health sciences0302 clinical medicinesensory predictionmotioninternal-modelsVertical directionHumansgravitational forcepointing movementsCerebral CortexVestibular systemBrain Mappinginternal modelhuman vestibular cortexNeural correlates of consciousnessNeuroscience (all)hand movementsGeneral NeurosciencefMRIBrainMiddle Agedmanual interceptionsHandMagnetic Resonance Imaging030104 developmental biology[ SDV.NEU ] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]insular cortex[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]PsychologyNeuroscience030217 neurology & neurosurgeryGravitationNeuroscience
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Stimulatory TSH-Receptor Antibodies and Oxidative Stress in Graves Disease

2018

CONTEXT: We hypothesized that TSH-receptor (TSHR) stimulating antibodies (TSAbs) are involved in oxidative stress mechanisms in patients with Graves disease (GD). METHODS: Nicotinamide adenine dinucleotide phosphate oxidase, isoform 2 (NOX2); oxidative parameters; and oxidative burst were measured in serum, urine, and whole blood from patients with GD and control subjects. Superoxide production was investigated in human embryonic kidney (HEK)-293 cells stably overexpressing the TSHR. Lipid peroxidation was determined by immunodot-blot analysis for protein-bound 4-hydroxy-2-nonenal (4-HNE) in human primary thyrocytes and HEK-293–TSHR cells. RESULTS: Serum NOX2 levels were markedly higher in …

AdultMale0301 basic medicineendocrine systemmedicine.medical_specialtyendocrine system diseasesEndocrinology Diabetes and MetabolismGraves' diseaseClinical Biochemistry030209 endocrinology & metabolismContext (language use)medicine.disease_causeBiochemistryLipid peroxidation03 medical and health scienceschemistry.chemical_compound0302 clinical medicineEndocrinologyInternal medicinemedicineHumansEuthyroidClinical Research ArticlesTriiodothyroninebusiness.industryBiochemistry (medical)Toxic nodular goiterReceptors ThyrotropinMiddle AgedPrognosismedicine.diseaseGraves DiseaseRespiratory burstOxidative StressHEK293 Cells030104 developmental biologyEndocrinologychemistryFemaleLipid PeroxidationbusinessBiomarkershormones hormone substitutes and hormone antagonistsOxidative stressFollow-Up StudiesImmunoglobulins Thyroid-StimulatingThe Journal of Clinical Endocrinology & Metabolism
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PTPN22 and CTLA-4 Polymorphisms Are Associated With Polyglandular Autoimmunity

2017

Context Single nucleotide polymorphisms (SNPs) of various genes increase susceptibility to monoglandular autoimmunity. Data on autoimmune polyglandular syndromes (APSs) are scarce. Objective Evaluate potential associations of eight SNPs with APSs. Setting Academic referral endocrine clinic. Patients A total of 543 patients with APS and monoglandular autoimmunity and controls. Intervention The SNP protein tyrosine phosphatase nonreceptor type 22 (PTPN22) rs2476601 (+1858); cytotoxic T-lymphocyte‒associated antigen 4 (CTLA-4) rs3087243 (CT60) and rs231775 (AG49); vitamin D receptor (VDR) rs1544410 (Bsm I), rs7975232 (Apa I), rs731236 (Taq I); tumor necrosis factor α rs1800630 (-863); and inte…

AdultMale0301 basic medicinemedicine.medical_specialtyGenotypeEndocrinology Diabetes and MetabolismGraves' diseaseClinical Biochemistry030209 endocrinology & metabolismSingle-nucleotide polymorphismPolymorphism Single NucleotideBiochemistryCalcitriol receptorPTPN22Young Adult03 medical and health sciences0302 clinical medicineEndocrinologyGene FrequencyInternal medicinemedicineHumansCTLA-4 AntigenGenetic Predisposition to DiseasePolyendocrinopathies AutoimmuneAllele frequencyGenetic Association Studiesbusiness.industryBiochemistry (medical)HaplotypeCase-control studyProtein Tyrosine Phosphatase Non-Receptor Type 22Odds ratioMiddle Agedmedicine.disease030104 developmental biologyEndocrinologyCase-Control StudiesFemalebusinessThe Journal of Clinical Endocrinology & Metabolism
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