Search results for "RAV"

showing 10 items of 5866 documents

Transcranial Magnetic Stimulation Combined With Nicotine Replacement Therapy for Smoking Cessation: A Randomized Controlled Trial.

2015

Abstract Background Further evidence suggests that repetitive Transcranial Magnetic Stimulation (rTMS) is an effective method to reduce tobacco craving among smokers. Hypothesis As relapse is common within a few days after smoking cessation, we hypothesized that combining the anti-craving effects of rTMS with Nicotine replacement therapy (NRT) to attenuate withdrawal symptoms could increase abstinence rates in smokers with severe nicotine dependence who quit smoking. Methods Thirty-seven smokers who failed to quit with the usual treatments were randomly assigned to two treatment groups to receive either active ( n  = 18) or sham ( n  = 19) 1-Hz rTMS of the right dorsolateral prefrontal cort…

CessationAdultMaleNicotinemedicine.medical_specialtymedicine.medical_treatmentmedia_common.quotation_subjectBiophysicsPrefrontal CortexCravingbehavioral disciplines and activitieslcsh:RC321-571law.inventionNicotineYoung AdultRandomized controlled triallawTobaccomental disordersmedicineHumansSingle-Blind MethodPsychiatrylcsh:Neurosciences. Biological psychiatry. Neuropsychiatrymedia_commonCravingGeneral NeuroscienceTobacco Use DisorderAbstinenceMiddle AgedNicotine replacement therapyCombined Modality TherapyTranscranial Magnetic StimulationTobacco Use Cessation DevicesTranscranial magnetic stimulationTreatment Outcomenervous systemAnesthesiaCombinationbehavior and behavior mechanismsSmoking cessationFemaleSmoking CessationNeurology (clinical)medicine.symptomTobacco Use Cessation ProductsPsychologypsychological phenomena and processesmedicine.drugBrain stimulation
researchProduct

Channel Tracking Guidewire and Technique for Retrograde Approach

2020

Evaluation of the collateral circulation is critical for determining the feasibility of the retrograde approach. When assessing collateral channels it is of paramount importance to take time and review the previous angiogram carefully, for multiple potential collateral pathways, as the predominant collateral may change over time prior to the procedure. Careful review of collaterals prior to the procedure can reduce contrast and radiation dose as well as the duration of the procedure.Retrograde access to the distal vessel can be achieved via septal collaterals, epicardial collaterals (atrial channel), or (patent or occluded) coronary bypass grafts. Generally septals are used more often 65–70…

Change over timemedicine.medical_specialtyCollateralComputer scienceRadiation dosemedicineRetrograde approachRadiologyCollateral circulationAngiography Chronic Total Occlusion Intravascular Ultrasound Percutaneous Coronary InterventionCommunication channel
researchProduct

A comparative study of the physicochemical properties of iron isomaltoside 1000 (Monofer®), a new intravenous iron preparation and its clinical impli…

2011

Abstract The treatment of iron deficiency anemia with polynuclear iron formulations is an established therapy in patients with chronic kidney disease but also in other disease areas like gastroenterology, cardiology, oncology, pre/post operatively and obstetrics’ and gynecology. Parenteral iron formulations represent colloidal systems in the lower nanometer size range which have traditionally been shown to consist of an iron core surrounded by a carbohydrate shell. In this publication, we for the first time describe the novel matrix structure of iron isomaltoside 1000 which differs from the traditional picture of an iron core surrounded by a carbohydrate. Despite some structural similaritie…

Chemical PhenomenaDrug CompoundingPharmaceutical ScienceIntravenous ironIron sucroseSodium ferric gluconateDisaccharidesFerric Compoundschemistry.chemical_compoundDrug Delivery SystemsIron Isomaltoside 1000medicineHumansParticle SizeInfusions IntravenousMolecular StructureHydrolysisRadiochemistryGeneral MedicineVitaminsCarbohydratemedicine.diseaseFerumoxytolMolecular WeightDextranBiochemistryIron-deficiency anemiachemistryBiotechnologymedicine.drug
researchProduct

Short hydrogen bonds enhance nonaromatic protein-related fluorescence

2021

Significance Intrinsic fluorescence of nonaromatic amino acids is a puzzling phenomenon with an enormous potential in biophotonic applications. The physical origins of this effect, however, remain elusive. Herein, we demonstrate how specific hydrogen bond networks can modulate fluorescence. We highlight the key role played by short hydrogen bonds, present in the protein structure, on the ensuing fluorescence. We provide detailed experimental and molecular evidence to explain these unusual nonaromatic optical properties. Our findings should benefit the design of novel optically active biomaterials for applications in biosensing and imaging.

Chemical transformationOptics and PhotonicsGlutamineIntrinsic fluorescenceMolecular Dynamics SimulationPhotochemistryFluorescenceAb initio molecular dynamicsAmmoniaHumansSingle amino acidshort hydrogen bondDensity Functional TheoryMultidisciplinaryHydrogen bondChemistryintrinsic fluorescenceultraviolet fluorescenceHydrogen BondingConical intersectionFluorescenceBiophysics and Computational BiologyExcited statePhysical Sciences408PeptidesProceedings of the National Academy of Sciences of the United States of America
researchProduct

Three simultaneous dissolution profiles on a solid pharmaceutical formulation by a FIA manifold provided with a single spectrophotometric detector.

2003

This article deals with the simultaneous determination of three dissolution profiles in the same pharmaceutical formulation. The officially proposed procedure from the pharmacopoeias is adapted to the FIA methodology to obtain the officially recommended profile or "global profile", and two "individual" profiles, corresponding to dissolution rate of two different active principles present in the formulation; both drugs have overlapped UV-vis spectra. The simultaneous determination of several profiles is based on the derivative spectra and the zero crossing mathematical procedure for the "individual" profiles of an active principle; the "global" profile of the formulation is obtained from the…

Chemistry PharmaceuticalClinical BiochemistryPharmaceutical ScienceDerivativePharmaceutical formulationPlot (graphics)Dosage formSpectral lineAnalytical ChemistryDrug DiscoveryApplied mathematicsSpectroscopyClavulanic AcidAntibacterial agentFlow injection analysisChromatographyChemistryAmoxicillinZero crossingBromhexinePharmaceutical SolutionsPharmaceutical PreparationsSolubilityFlow Injection AnalysisSpectrophotometry UltravioletTabletsJournal of pharmaceutical and biomedical analysis
researchProduct

Evaluation of gliadins-diglycosylated cyanidins interaction from litchi pericarp through ultraviolet and fluorescence measurements

2017

The low stability of anthocyanins limits their use in industry, which can be surpassed by gliadins linkage. This work was aimed to study the anthocyanins-gliadins bonding properties. HPLC-DAD-ESI-M...

Chemistry010401 analytical chemistryantioxidant activity04 agricultural and veterinary sciencesLinkage (mechanical)medicine.disease_causePhotochemistry040401 food science01 natural sciencesFluorescencegliadins0104 chemical scienceslaw.invention0404 agricultural biotechnologylawultravioletmedicineLitchi pericarp anthocyaninsantioxidant activity; fluorescence; gliadins; Litchi pericarp anthocyanins; ultraviolet; Food SciencefluorescenceUltravioletFood Science
researchProduct

Red and far-red sun-induced chlorophyll fluorescence as a measure of plant photosynthesis

2015

Remote estimation of Sun-induced chlorophyll fluorescence emitted by terrestrial vegetation can provide an unparalleled opportunity to track spatiotemporal variations of photosynthetic efficiency. Here we provide the first direct experimental evidence that the two peaks of the chlorophyll fluorescence spectrum can be accurately mapped from high-resolution radiance spectra and that the signal is linked to variations in actual photosynthetic efficiency. Red and far red fluorescence measured using a novel airborne imaging spectrometer over a grass carpet treated with an herbicide known to inhibit photosynthesis was significantly higher than the corresponding signal from an equivalent untreated…

Chemistry1900 General Earth and Planetary SciencesImaging spectrometerfood and beveragesFar-redPhotosynthetic efficiencyPhotosynthesisFluorescenceGEO/10 - GEOFISICA DELLA TERRA SOLIDA10122 Institute of GeographyGeophysicsRadianceddc:550General Earth and Planetary Sciences910 Geography & travel1908 GeophysicsControlled experimentfluorescence airborne sensor high resolution photosynthesisChlorophyll fluorescenceRemote sensing
researchProduct

Study of Mechanisms of Light-Induced Dissociation of Ru(dcbpy)(CO)2I2 in Solution down to 20 fs Time Resolution

2006

Mechanisms of the light-induced ligand exchange reaction of (trans-I) Ru(dcbpy)(CO)2I2 (dcbpy = 4,4'-dicarboxylic acid-2,2'-bipyridine) in ethanol have been studied by transient absorption spectroscopy. Ultraviolet 20 fs excitation pulses centered at 325 nm were used to populate a vibrationally hot excited pi bipyridyl state of the reactant that quickly relaxes to a dissociative Ru-I state resulting in the release of one of the carbonyl groups. Quantum yield measurements have indicated that about 40% of the initially exited reactant molecules form the final photoproduct. A 62 fs rise component in the transient absorption (TA) signal was observed at all probe wavelengths in the visible regio…

ChemistryAnalytical chemistryQuantum yieldPhotochemistrymedicine.disease_causeDissociation (chemistry)Surfaces Coatings and FilmsExcited stateUltrafast laser spectroscopyMaterials ChemistrymedicineMoleculePhysical and Theoretical ChemistrySpectroscopyExcitationUltravioletThe Journal of Physical Chemistry B
researchProduct

Water vapour adsorption onto Ca2+ Camp–Berteau montmorillonite and comparison with properties of Na+ sample

2004

Abstract In this paper, we present an analysis of the adsorbed amounts and adsorption heats of water vapour of Ca2+ Camp–Berteau montmorillonite. Measurements were obtained at 298 K using thermogravimetry and calorimetry as a function of relative pressure and the study was completed by the adsorption of nitrogen at 77 K. Experimental data were analysed with BET and t-method theories and compared with those of the Na+ sample. A correlation was shown between models and two domains observed on the calorimetric curves. These domains have been attributed to a multilayer equivalent adsorption. However, the determination of the surface area of clays remains a difficulty. So, the areas of interlaye…

ChemistryAnalytical chemistrychemistry.chemical_elementMineralogyCalorimetryCondensed Matter PhysicsNitrogenThermogravimetrychemistry.chemical_compoundMontmorilloniteAdsorptionRelative pressurePhysical and Theoretical ChemistryInstrumentationWater vaporThermochimica Acta
researchProduct

On the relaxation mechanisms of 6-azauracil

2011

The nonadiabatic photochemistry of 6-azauracil has been studied by means of the CASPT2//CASSCF protocol and double-ζ plus polarization ANO basis sets. Minimum energy states, transition states, minimum energy paths, and surface intersections have been computed in order to obtain an accurate description of several potential energy hypersurfaces. It is concluded that, after absorption of ultraviolet radiation (248 nm), two main relaxation mechanisms may occur, via which the lowest (3)(ππ*) state can be populated. The first one takes place via a conical intersection involving the bright (1)(ππ*) and the lowest (1)(nπ*) states, ((1)ππ*/(1)nπ*)(CI), from which a low-energy singlet-triplet crossin…

ChemistryConical intersectionPotential energyTransition stateSurfaces Coatings and FilmsMaterials ChemistryEnergy levelQuantum TheoryThermodynamicsPhysical and Theoretical ChemistryAtomic physicsTriplet stateGround stateUracilUltraviolet radiationFOTOQUÍMICA
researchProduct