Search results for "RDA"
showing 10 items of 1560 documents
Recomendaciones en el manejo de la pandemia por coronavirus SARS-CoV-2 (Covid-19) en pacientes con trasplante renal
2020
The SARS-CoV-2 (Covid-19) coronavirus pandemic is evolving very quickly and means a special risk for both immunosuppressed and comorbid patients. Knowledge about this growing infection is also increasing although many uncertainties remain, especially in the kidney transplant population. This manuscript presents a proposal for action with general and specific recommendations to protect and prevent infection in this vulnerable population such as kidney transplant recipients. Resumen: La pandemia por coronavirus SARS-CoV-2 (Covid-19) está evolucionando de manera muy rápida y representa un riesgo especial en pacientes inmunodeprimidos y con comorbilidades añadidas. El conocimiento sobre esta in…
Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the a…
2015
Chronic alcohol exposure reduces endocannabinoid activity and disrupts adult neurogenesis in rodents, which results in structural and functional alterations. Cannabinoid receptor agonists promote adult neural progenitor cell (NPC) proliferation. We evaluated the protective effects of the selective CB1 receptor agonist ACEA, the selective CB2 receptor agonist JWH133 and the fatty-acid amide-hydrolase (FAAH) inhibitor URB597, which enhances endocannabinoid receptor activity, on NPC proliferation in rats with forced consumption of ethanol (10%) or sucrose liquid diets for 2 weeks. We performed immunohistochemical and stereological analyses of cells expressing the mitotic phosphorylation of his…
Grip Strength, Neurocognition, and Social Functioning in People WithType-2 Diabetes Mellitus, Major Depressive Disorder, Bipolar Disorder, and Schizo…
2020
[Background] Frailty is a common syndrome among older adults and patients with several comorbidities. Grip strength (GS) is a representative parameter of frailty because it is a valid indicator of current and long-term physical conditions in the general population and patients with severe mental illnesses (SMIs). Physical and cognitive capacities of people with SMIs are usually impaired; however, their relationship with frailty or social functioning have not been studied to date. The current study aimed to determine if GS is a valid predictor of changes in cognitive performance and social functioning in patients with type-2 diabetes mellitus and SMIs.
Producción y difusión digitales de las humanidades no vanguardistas en el siglo XX: el ejemplo de la filología catalana medieval
2014
Aquest article ofereix un panorama històric dels formats digitals emprats al segle XX en un petit camp de les Humanitats: la filologia catalana medieval, com a exemple de moltes altres àrees de recerca similars, no avantguardistes, i centrades en estudis textuals. S'hi mostra que la gestió textual i de vocabulari, així com les bades de dades lèxiques i bibliogràfiques, van constituir els seus primers projectes. L'article conclou amb una brevíssima valoració dels desafiaments digitals en el futur immediat, especialment en eines de publicació: pdf front a epub, i l'accelerat procés de compartir la recerca més recent a través de les xarxes socials d'investigadors. S'hi defén la via de la cultu…
Contra la patologización intensiva en términos de derechos humanos: Activismo gordo en Argentina
2020
This work addresses the way in which Argentine Fat Activism has developed, in recent years, the demand for depathologization of fatness, taking elements from critical discourses on the health of fat people to frame them in a perspective typical of the Human Rights. First, the contemporary fat body is described in terms of stigma and discrimination, especially in the health field. Then, they refer to a series of critical positions on the pathologization and medicalization of fatness from the biomedical perspective, Fat Studies and Fat Activism. Lastly, a series of interventions that the Argentine activist collective Taller Hacer la Vista Gorda produced between 2017 and 2020 were considered, …
A conceptual model of feedback mechanisms in adjusted affordances – Insights from usage of a mental mobile health application
2023
Affordance theory provides one of the most prominent lenses through which the socio-technical aspects of a system’s use can be investigated and understood. In this context, the literature has proposed that perceived and actualized affordances may be adjusted over time. Yet, how the adjustment of affordances occurs has not been explained in detail. Thus, in this article, we develop a conceptual model of feedback mechanisms that includes a more explicit description of how affordances are perceived by users, whether actualized and adjusted. With the model, we introduce the central concept of a generative base, out of which affordance perceptions emerge and which can be updated through affordan…
Tiesnešu atsevišķās domas kā tiesību palīgavots. Augstākās tiesas Administratīvo lietu departamenta pieredze (2014.-2017.)
2018
Bakalaura darba tēmas nosaukums ir „Tiesnešu atsevišķās domas kā tiesību palīgavots. Augstākās tiesas Administratīvo lietu departamenta pieredze (2014.-2017.) ”. Tā kā tiesnešu atsevišķās domas nav bieži sastopamas, šī darba mērķis ir noskaidrot kādu ietekmi sniedz tiesneša atsevišķo domu institūts. Lai to noskaidrotu, darba autore analizē tiesību zinātnieku dažādos viedokļus par tiesnešu atsevišķo domu institūta esību. Autore klasificē tiesneša atsevišķo domu iedalījuma kritērijus un aplūko tiesnesim piešķirtās brīvības, vārda brīvību un neatkarību, tiesneša atsevišķo domu izpratnē. Salīdzinošā nolūkā tiek apskatīts ne tikai Latvijas, bet arī citu valstu normatīvais regulējums. Darba autor…
Saistība starp pieaugušo piesaistes veidiem, bērnības vardarbības pieredzi un vardarbību partnerattiecībās
2002
Determination of 21 perfluoroalkyl substances and organophosphorus compounds in breast milk by liquid chromatography coupled to orbitrap high-resolut…
2018
Abstract The human exposure to perfluoroalkyl (PFASs) and organophosphorus (OPs) compounds is a cause of concern and its determination in biological matrices, including human milk, is an emergent approach for evaluate their exposure. A comprehensive strategy for the quantitative determination of 21 PFASs and OPs compounds in breast milk was developed. The proposed method includes an extraction and clean-up procedure based on the QuEChERs methodology followed by an ultra-high performance liquid chromatography coupled to high-resolution mass spectrometry (UHPLC-HRMS) determination. The full-scan mass data were acquired with a resolution of 50000 FWHM and a mass accuracy better than 5 ppm. Met…
False positive rate of an arrayCGH platform for single-cell preimplantation genetic screening and subsequent clinical application on day-3
2013
In this work, false positive rate of an arrayCGH platform for its use in day-3 single-blastomere analysis was calculated. For this purpose, 38 embryos diagnosed as abnormal on day-3 by FISH were re-biopsied on day-4. Single-cell day-4 arrayCGH diagnosis was then performed. A successful amplification was obtained in 97.4 % (37/38) of the day-4 cells analysed by arrayCGH. Day-3 FISH and day-4 arrayCGH diagnosis were concordant in 35/37 cases. The two discordant embryos were spread and all the cells from each embryo were re-analysed by FISH on day 5. The same error rate (2.7 %) for day-3 FISH and day-4 arrayCGH was obtained when comparing day-5 FISH re-analysis. After this pre-clinical phase, …