Search results for "READING"

showing 10 items of 1521 documents

Childhood Verbal Development and Drinking Behaviors from Adolescence to Young Adulthood: A Discordant Twin-Pair Analysis

2012

BACKGROUND: Studies suggest that better cognitive and verbal abilities in childhood predict earlier experimentation with alcohol and higher levels of drinking in adolescence, whereas poorer ability is related to a higher likelihood of remaining abstinent. Whether individual differences in language development in childhood predict differences in adolescent drinking behaviors has not been studied. METHODS: To address that question, we compared co-twins from twin pairs discordant for their childhood language development and studied associations of parental reports of within-pair differences in age at speaking words, age at learning to read, and expressive language skills during school age with…

MaleAgingAdolescentAlcohol DrinkingBirth weightPopulationMedicine (miscellaneous)Poison controlNeuropsychological TestsToxicologyLanguage DevelopmentArticleDevelopmental psychologyCohort StudiesYoung Adult03 medical and health sciencesChild Development0302 clinical medicineSurveys and QuestionnairesInjury preventionOdds RatioTwins DizygoticHumansLongitudinal StudiesYoung adultChildeducationFinlandta515Discordant Twineducation.field_of_studyData CollectionTwins Monozygotic030227 psychiatryAlcoholismPsychiatry and Mental healthLanguage developmentBirth orderLogistic ModelsReadingEducational StatusFemalePsychology030217 neurology & neurosurgeryAlcoholism : Clinical and Experimental Research
researchProduct

Post-transcriptional analysis of rat mitochondrial D-3-hydroxybutyrate dehydrogenase control through development and physiological stages.

1991

Abstract The nuclear encoded mitochondrial D -3-hydroxybutyrate dehydrogenase (BDH) is synthesized in the cytosal as a larger precursor. This membrane enzyme which requires lecithin for activity plays an essential role in energy metabolism as a ketone bodies-converting enzyme. A cDNA clone of the rat liver enzyme encompassing an antigenic determinant peptide has been isolated after immunoscreening of a λ gt11 expression library. The nucleotide sequence of this 279-base cDNA insert contains a single open reading frame of 93 amino-acids, which represents about a third of the mature enzyme. Amino-acid sequence analysis predicts a hydrophobic stretch of 29 amino-acids long which probably functi…

MaleAgingBlotting WesternMolecular Sequence DataBiologyGene Expression Regulation EnzymologicEnzyme activatorHydroxybutyrate DehydrogenaseComplementary DNAImmunoscreeningGene expressionAnimalsAmino Acid SequenceCloning MolecularRNA Processing Post-TranscriptionalGenechemistry.chemical_classificationMessenger RNASex CharacteristicsBase SequenceEstradiolRats Inbred StrainsCell BiologyGeneral MedicineDNABlotting NorthernEmbryo MammalianMolecular biologyDietary FatsMitochondriaRatsOpen reading frameEnzymeBiochemistrychemistryOrgan SpecificityFemaleCorticosteroneBiology of the cell
researchProduct

SARS CoV2 infection _The longevity study perspectives

2021

Graphical abstract

MaleAgingssRNA single-stranded RNARFLP restriction fragment length polymorphismHSPs heat shock proteinsReviewPTMs post-translational modificationsSevere Acute Respiratory SyndromeBiochemistryHIV-1 human immunodeficiency virus-1TNF-α tumor necrosis factor-αEC endothelial cells0302 clinical medicineFluAV influenza A virusI insertionMedicineIFN-γ interferon-γDIC disseminated intravascular coagulationPCR Polymerase Chain Reactionmedia_commonAged 80 and overLongevityRBD receptor-binding domainNeurologyLongevity modelMI myocardial infarctionNK natural killerhPIV2 human parainfluenza virus type 2media_common.quotation_subjectResearching genetic basis of resistance and potential pharmacological targetsLongevityDBP diastolic blood pressureNF-Kb nuclear transcription factor kBRANTES regulated upon activation normal T cell expressed and secretedMphi human macrophages03 medical and health sciencesCox 2 cyclooxygenase 2ORF open reading framePT prothrombin timeSettore MED/05 - Patologia ClinicaHumansMolecular BiologyInflammatory genesARDS acute respiratory distress syndromeNO nitric oxideD deletionCpGIs CpG islandsT2DM type 2 diabetes mellitusmedicine.diseaseFDP fibrin degradation products030104 developmental biologySARS CoV2 severe acute respiratory syndrome Coronavirus 2 virusImmunologyBMI body max indexItalian nonagenarians/centenariansRSV respiratory syncytial virusComplication030217 neurology & neurosurgeryMAPK mitogen-activated protein kinaseIP-10 IFN-γ -Inducible Protein 1040301 basic medicineAT1R activity of angiotensin 1 receptorsDCs dentritic cellsSSCP single strand conformation polymorphismACE/DD polymorphism of the angiotensin converting enzymeFGF21 fibroblast growth factor 21TLR4 toll-like receptor 4NAD nicotinamide adenine dinucleotideACE angiotensin-I converting enzymeAT2R activity of angiotensin 2 receptorsCOVID-19 Coronavirus disease 2019Respiratory distressACE2 angiotensin converting enzyme 2MKP-1 mitogen-activated protein kinase phosphatase-1 ()PD protease domainSNP single nucleotide polymorphismEH essential hypertensionTNFR tumor necrosis factor receptorINR international normalized ratio of the prothrombin timePAI-1 plasminogen activator inhibitor-1Ang angiotensinLPS lipopolysaccharideMCP1 monocyte chemoattractant protein-1medicine.symptomaPTT partial thromboplastin timeBiotechnologyDUSP1 dual specificity phosphatase 1Coronavirus disease 2019 (COVID-19)PC prostate cancerRAS renin-angiotensin aldosterone systemCCR5Δ32 genetic variant of chemokine receptorCOVID-19 Researching genetic basis of resistance and potential pharmacological targets Italian nonagenarians/centenarians Longevity modelAsymptomaticSARS-1 severe acute respiratory syndrome virus 1SIRT-1 Sirtuin 1Th1 t-helper lymphocyte type 1Immune systemROS reactive oxygen speciesTGF-β transforming growth factor betaET-1 endothelin-1ComputingMethodologies_COMPUTERGRAPHICSADAM-17 metallopeptidase domain 17business.industrySARS-CoV-2SBP systolic blood pressureCOVID-19HDACs histone deacetylasesComorbidityImmune Systembusiness5-LO lipoxygenase 5Ageing Research Reviews
researchProduct

Working memory and children’s use of retrieval to solve addition problems

2005

This study tested the hypothesis that children with high working memory capacities solve single-digit additions by direct retrieval of the answers from long-term memory more often than do children with low working memory capacities. Counting and reading letter span tasks were administered to groups of third-grade (mean age=107 months) and fourth-grade (mean age=118 months) children who were also asked to solve 40 single-digit additions. High working memory capacity was associated with more frequent use of retrieval and faster responses in solving additions. The effect of span on the use of retrieval increased with the size of the minimum addend. The relation between working memory measures …

MaleAnalysis of VarianceWorking memoryLong-term memoryReading (computer)Short-term memoryExperimental and Cognitive PsychologyCognitionChild developmentChild DevelopmentReadingMemoryMental RecallReaction TimeDevelopmental and Educational PsychologyMemory spanHumansMathematical abilityFemaleChildPsychologyMathematicsProblem SolvingCognitive psychologyJournal of Experimental Child Psychology
researchProduct

Auditory event-related potentials measured in kindergarten predict later reading problems at school age.

2013

Identifying children at risk for reading problems or dyslexia at kindergarten age could improve support for beginning readers. Brain event-related potentials (ERPs) were measured for temporally complex pseudowords and corresponding non-speech stimuli from 6.5-year-old children who participated in behavioral literacy tests again at 9 years in the second grade. Children who had reading problems at school age had larger N250 responses to speech and non-speech stimuli particularly at the left hemisphere. The brain responses also correlated with reading skills. The results suggest that atypical auditory and speech processing are a neural-level risk factor for future reading problems. [Supplement…

MaleAuditory eventmedia_common.quotation_subjectSpeech soundsLateralization of brain functionLiteracyDevelopmental psychologyDyslexiaPhoneticsotorhinolaryngologic diseasesDevelopmental and Educational PsychologymedicineHumansSpeechChildta515media_commonAnalysis of VarianceBrain MappingSchool age childDyslexiaBrainElectroencephalographymedicine.diseaseSpeech processingReading ProblemsNeuropsychology and Physiological PsychologyAcoustic StimulationReadingCase-Control StudiesEvoked Potentials AuditorySpeech PerceptionFemalePsychologyDevelopmental neuropsychology
researchProduct

Got rhythm… for better and for worse. Cross-modal effects of auditory rhythm on visual word recognition

2013

The present research aimed to investigate whether, as previously observed with pictures, background auditory rhythm would also influence visual word recognition. In a lexical decision task, participants were presented with bisyllabic visual words, segmented into two successive groups of letters, while an irrelevant strongly metric auditory sequence was played in a loop. The first group of letters could either be congruent with the syllabic division of the word (e.g. val in val/se) or not (e.g. va in va/lse). In agreement with the Dynamic Attending Theory (DAT), our results confirmed that the presentation of the correct first syllable on-beat (i.e. in synchrony with a peak of covert attentio…

MaleAuditory perceptionLinguistics and LanguageSpeech perceptionVisual perceptionCognitive Neurosciencemedia_common.quotation_subjectExperimental and Cognitive Psychology050105 experimental psychologyLanguage and LinguisticsYoung Adult03 medical and health sciences0302 clinical medicineRhythmPerceptionReaction TimeDevelopmental and Educational PsychologyLexical decision taskHumansAttention0501 psychology and cognitive sciencesmedia_common05 social sciencesRecognition PsychologyCognitionReadingWord recognitionAuditory PerceptionSpeech PerceptionVisual PerceptionFemalePsychologyMusicPhotic StimulationPsychomotor Performance030217 neurology & neurosurgeryCognitive psychologyCognition
researchProduct

Media multitasking is associated with distractibility and increased prefrontal activity in adolescents and young adults.

2016

The current generation of young people indulges in more media multitasking behavior (e.g., instant messaging while watching videos) in their everyday lives than older generations. Concerns have been raised about how this might affect their attentional functioning, as previous studies have indicated that extensive mediamultitasking in everyday life may be associated with decreased attentional control. In the current study, 149 adolescents and young adults (aged 13-24 years) performed speech-listening and reading tasks that required maintaining attention in the presence of distractor stimuli in the othermodality or dividing attention between two concurrent tasks. Brain activity during task pe…

MaleBrain activity and meditationAudiologymedia multitaskingBrain mappingDevelopmental psychology0302 clinical medicineCOGNITIVE CONTROLTask Performance and AnalysisAttentionBRAINPLASTICITYEveryday lifeta515prefrontal cortexBrain Mappingmedicine.diagnostic_test05 social sciencesfMRIMultitasking BehaviorNeurologyMultimediaAuditory PerceptionFemalePsychologyRESPONSE-INHIBITIONpsychological phenomena and processesmedicine.medical_specialtyCORTEXAdolescent515 PsychologyCognitive NeurosciencePrefrontal CortexAffect (psychology)behavioral disciplines and activitiesta3112050105 experimental psychology03 medical and health sciencesYoung AdultWORKING-MEMORYmedicineHuman multitaskingHumans0501 psychology and cognitive sciencestarkkaavaisuusWorking memoryAttentional controlPERFORMANCEFRONTAL LESIONSMedia multitaskingLIFEReading516 Educational sciencesSUSTAINED ATTENTIONNerve NetFunctional magnetic resonance imaging030217 neurology & neurosurgeryNeuroImage
researchProduct

Reading skill and neural processing accuracy improvement after a 3-hour intervention in preschoolers with difficulties in reading-related skills

2012

This study aimed at determining whether an intervention game developed for strengthening phonological awareness has a remediating effect on reading skills and central auditory processing in 6-year-old preschool children with difficulties in reading-related skills. After a 3-hour training only, these children made a greater progress in reading-related skills than did their matched controls who did mathematical exercises following comparable training format. Furthermore, the results suggest that this brief intervention might be beneficial in modulating the neural basis of phonetic discrimination as an enhanced speech-elicited mismatch negativity (MMN) was seen in the intervention group, indic…

MaleBrain activity and meditationmedia_common.quotation_subjecteducationMismatch negativityRecognition (Psychology)behavioral disciplines and activitiesEarly Intervention (Education)050105 experimental psychologyDevelopmental psychologyDyslexia03 medical and health sciencesDiscrimination Psychological0302 clinical medicinePhoneticsPhonological awarenessEvent-related potentialIntervention (counseling)Reading (process)Early Intervention EducationalmedicineHumansRemedial Teaching0501 psychology and cognitive sciencesChildEvoked PotentialsMolecular Biologyta515media_commonAuditory CortexDiscrimination (Psychology)General Neuroscience05 social sciencesDyslexiaRecognition PsychologyElectroencephalographymedicine.diseaseGames ExperimentalReadingData Interpretation StatisticalAuditory PerceptionFemaleNeurology (clinical)Brief interventionPsychologyPsychomotor Performance030217 neurology & neurosurgeryDevelopmental BiologyBrain Research
researchProduct

Cluster analysis of mrna expression levels identifies multiple sequential patterns following focal cerebral ischemia

2012

AIM The purpose of this study is to detect gene expression patterns following focal cerebral ischemia. MATERIAL AND METHODS 25 male Wistar rats were divided into control (n = 8) and ischemic (n = 17) groups. In the ischemic group, slowly progressing focal ischemia was simulated by two-vein occlusion with spreading depression (SD) a cortical microinjection of KCl induced. Ischemic tissue was removed at 2, 8, 24, or 72 h postischemia. Using semiquantitative reverse transcription polymerase chain reaction, we investigated mRNA expression levels of 13 representative genes related to cerebral ischemia. Cluster analysis of the gene expression levels was done. RESULTS In the ischemic group, the ex…

MaleCerebral veinsmedicine.medical_specialtyTranscription GeneticPhotochemistryIschemiaNerve Tissue ProteinsReal-Time Polymerase Chain ReactionBioinformaticsPotassium ChlorideCyclin D1Internal medicineGene expressionElectric ImpedancemedicineAnimalsCluster AnalysisRNA MessengerRats WistarCerebral Cortexbusiness.industryCortical Spreading Depressionmedicine.diseaseCerebral VeinsRatsReverse transcription polymerase chain reactionmedicine.anatomical_structureEndocrinologyReal-time polymerase chain reactionIschemic Attack TransientCerebral cortexCortical spreading depressionSurgeryNeurology (clinical)Intracranial ThrombosisbusinessTurkish Neurosurgery
researchProduct

A computer-based Pinyin intervention for disadvantaged children in China: Effects on Pinyin skills, phonological awareness, and character reading.

2019

Pinyin is an alphabetic script that denotes pronunciations of Chinese characters. Studies have shown that Pinyin instruction enhances both phonological awareness (e.g., Shu et al., Developmental Science, 2008, 11, 171-181) and character reading (e.g., Lin et al., Psychological Science, 2010, 21, 1117-1122) in Chinese children. In the present study, we provided a 3-week Pinyin intervention with a computer-based Pinyin GraphoGame to disadvantaged migrant children with poor Pinyin skills. A total of 252 first graders who were children of migrant workers in a large Chinese city were assessed to identify poor Pinyin readers. Fifty-six 7-year-old children with poor Pinyin skills were selected and…

MaleChinamedia_common.quotation_subjectExperimental and Cognitive PsychologyVulnerable Populations050105 experimental psychologyLiteracyEducationDevelopmental psychologyDyslexiaFluencyPhonological awarenessPhoneticsReading (process)Developmental and Educational PsychologymedicineHumans0501 psychology and cognitive sciencesChildmedia_commonPhonemic awareness4. Education05 social sciencesPinyinDyslexia050301 educationGeneral MedicineAwarenessmedicine.diseaseCognitive RemediationReadingTherapy Computer-AssistedLanguage TherapyFemaleChinese charactersPsychology0503 educationDyslexia (Chichester, England)REFERENCES
researchProduct