Search results for "RECORD"

showing 10 items of 809 documents

Role of serotonin in central dopamine dysfunction

2010

The interaction between serotonin (5-HT) and dopamine (DA)-containing neurons in the brain is a research topic that has raised the interest of many scientists working in the field of neuroscience since the first demonstration of the presence of monoamine-containing neurons in the mid 1960. The bulk of neuroanatomical data available clearly indicate that DA-containing neurons in the brain receive a prominent innervation from serotonin (5-hydroxytryptamine, 5-HT) originating in the raphe nuclei of the brainstem. Compelling electrophysiological and neurochemical data show that 5-HT can exert complex effects on the activity of midbrain DA neurons mediated by its various receptor subtypes. The m…

Mesocorticolimbic DA systemNigrostriatal DA systemReceptor Serotonin 5-HTParkinson's diseaseBrain microdialysisAntidepressantDopaminergic functionAntidepressantsSettore BIO/09 - Fisiologia5-HT receptorAntipsychoticParkinson diseaseMicrodialysinervous systemSingle cell recordingDrug addictionAntidepressants;Antipsychotics;Dopaminergic function;Drug addiction;5-HT receptors;Mesocorticolimbic DA system;Microdialysis;Nigrostriatal DA system;Parkinson disease;Single cell recordingAntipsychotic drugs
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Between a rock and a soft place: the role of viruses in lithification of modern microbial mats.

2021

10 pages; International audience; Stromatolites are geobiological systems formed by complex microbial communities, and fossilized stromatolites provide a record of some of the oldest life on Earth. Microbial mats are precursors of extant stromatolites; however, the mechanisms of transition from mat to stromatolite are controversial and are still not well understood. To fully recognize the profound impact that these ecosystems have had on the evolution of the biosphere requires an understanding of modern lithification mechanisms and how they relate to the geological record. We propose here viral mechanisms in carbonate precipitation, leading to stromatolite formation, whereby viruses directl…

Microbiology (medical)Geologic SedimentsBiogeochemical cycleviral lifestyleEarth sciencevirus–host interactionsGeologic recordMicrobiologyMESH: Host-Parasite InteractionsHost-Parasite InteractionsMESH: Viruses03 medical and health sciencesGeologic time scalebacteriophageVirologylytic/lysogenic cyclevirusesMicrobial matstromatoliteLithification030304 developmental biologyearly Earth0303 health sciencesBacteriabiology030306 microbiologyMESH: Virus Physiological PhenomenamicrobialitesBiosphereexopolymeric substances (EPS)MESH: Geologic Sedimentsbiology.organism_classificationEarly Earthmicrobial matMESH: BacteriaInfectious Diseases[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologyStromatolite13. Climate actionCRISPRbiosignaturesVirus Physiological Phenomena
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Validation of intensive care unit-acquired infection surveillance in the Italian SPIN-UTI network

2010

Validity is one of the most critical factors concerning surveillance of nosocomial infections (NIs). This article describes the first validation study of the Italian Nosocomial Infections Surveillance in Intensive Care Units (ICUs) project (SPIN-UTI) surveillance data. The objective was to validate infection data and thus to determine the sensitivity, specificity, and positive and negative predictive values of NI data reported on patients in the ICUs participating in the SPIN-UTI network. A validation study was performed at the end of the surveillance period. All medical records including all clinical and laboratory data were reviewed retrospectively by the trained physicians of the validat…

Microbiology (medical)medicine.medical_specialtyMEDLINESensitivity and Specificitylaw.inventionlawPredictive Value of TestsIntensive carePositive predicative valueMedicineHumansIntensive care medicineRetrospective StudiesProtocol (science)Cross InfectionInfection Controlbusiness.industryMedical recordRetrospective cohort studyGeneral MedicineIntensive care unitIntensive Care UnitsInfectious DiseasesItalyPredictive value of testsEmergency medicinebusinessSentinel Surveillance
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Analysis of the process of environmental impact assessment for seawater desalination plants in Spain

2014

Desalination generates drinking water and enhances the economic, social, and environmental development of many areas with few water resources, such as parts of the Middle East, North Africa, and southern Europe (such as Spain and Cyprus). Desalination plants may cause environmental impacts in coastal areas and so it is necessary to submit plans for new plants to a process of environmental impact assessment (EIA) in order to achieve more environmentally viable projects, meaning: optimal locations; appropriately used systems and technologies; effective preventive, compensatory, and corrective measures; and social and environmental acceptance. This article contains a study of the process of en…

Middle EastProcess (engineering)Seawater desalinationMechanical EngineeringGeneral Chemical EngineeringEnvironmental impact assessmentNorth africaGeneral ChemistryEnvironmental impact statementDesalinationWater resourcesEnvironmental impact statementSpainSeawater desalination plantsEnvironmental scienceGeneral Materials ScienceEnvironmental impact assessmentPROYECTOS DE INGENIERIAEnvironmental planningRecords of decisionsWater Science and Technology
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Effects of different simplified milk recording methods on genetic evaluation with Test-Day animal model

2007

The aims of the present study were to compare estimated breeding values (EBV) for milk yield using different testing schemes with a test-day animal model and to evaluate the effect of different testing schemes on the ranking of top sheep. Alternative recording schemes that use less information than that currently obtained with a monthly test-day schedule were employed to estimate breeding values. A random regression animal mixed model that used a spline function of days in milk was fitted. EBVs obtained with alternative recording schemes showed different degrees of Spearman correlation with EBVs obtained using the monthly recording scheme. These correlations ranged from 0.77 to 0.92. A redu…

Mixed modelSchedulerecording schemesTest-Days Genetic Evaluation Recording SchemesAnimal Breeding and GenomicsSpearman's rank correlation coefficientgenetic evaluationSettore AGR/17 - Zootecnica Generale E Miglioramento Geneticorandom regression-modelsAnimal modelRankingTest dayRandom regressionStatisticsWIASsplinesFokkerij en GenomicaAnimal Science and Zoologylcsh:Animal culturetest-daysSelection (genetic algorithm)lcsh:SF1-1100MathematicsItalian Journal of Animal Science
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New insights into non-avian dinosaur reproduction and their evolutionary and ecological implications: linking fossil evidence to allometries of extan…

2013

It has been hypothesized that a high reproductive output contributes to the unique gigantism in large dinosaur taxa. In order to infer more information on dinosaur reproduction, we established allometries between body mass and different reproductive traits (egg mass, clutch mass, annual clutch mass) for extant phylogenetic brackets (birds, crocodiles and tortoises) of extinct non-avian dinosaurs. Allometries were applied to nine non-avian dinosaur taxa (theropods, hadrosaurs, and sauropodomorphs) for which fossil estimates on relevant traits are currently available. We found that the reproductive traits of most dinosaurs conformed to similar-sized or scaled-up extant reptiles or birds. The …

MultidisciplinaryFossil RecordbiologyPhylogenetic treeEcologyEcologyFossilsScienceQRZoologybiology.organism_classificationBiological EvolutionBird eggDinosaursTaxonExtant taxonPhylogeneticsAnimalsMedicineDinosaur reproductionPhylogenySauropodaResearch ArticlePLoS ONE
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Smarter, not harder.

2017

The purpose of this investigation was to compare and determine the relevance of the morphological characteristics and variability of running speed parameters (stride length and stride frequency) between Usain Bolt’s three best 100 m performances. Based on this, an attempt was made to define which factors determine the performance of Usain Bolt’s sprint and, therefore, distinguish him from other sprinters. We analyzed the previous world record of 9.69 s set in the 2008 Beijing Olympics, the current record of 9.58 s set in the 2009 Berlin World Championships in Athletics and the O lympic record of 9.63 s set in 2012 London Olympics Games by Usain Bolt. The application of VirtualDub Programme …

Multidisciplinaryanthropometric characteristicskinematic analysisSports scienceSection III – Sports TrainingMEDLINE030229 sport sciencesworld record03 medical and health sciences0302 clinical medicinesprintingHuman biologyEngineering ethicsSociology030217 neurology & neurosurgeryResearch ArticleNature
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Association between climate and new daily diagnoses of COVID-19

2020

AbstractBackgroundAlthough evidence is accumulating that climate conditions may positively or negatively influence the scale of coronavirus disease 2019 (COVID-19) outbreaks, uncertainty remains concerning the real impact of climate factors on viral transmission. Methods. The number of new daily cases of COVID-19 diagnosed in Verona (Italy) was retrieved from the official website of Veneto Region, while information on daily weather parameters in the same area was downloaded from IlMeteo website, a renowned Italian technological company specialized in weather forecasts. The search period ranged between March 1 to November 11, 2020. The number of new daily COVID-19 cases and meteorological da…

Multivariate analysisCoronavirus disease 2019 (COVID-19)Leadership and ManagementStrategy and Management2020. The number of new daily COVID-19 cases and meteorological data in Verona were correlated using both univariate and multivariate analysis. Results: The number of daily COVID-19 diagnoses in Verona was positively associated with the number of days in lockdown and humidity1% decrease in humidityWind speedmin and max temperatureand influence the likelihood or course of local COVID-19 outbreaks. Preventive measuresHealth Information Managementa renowned Italian technological company specialized in weather forecasts. The search period ranged between March 1 and November 11mean air temperature1.2% and 5.4% reduction in new COVID-19 daily diagnoses. A significant difference was observed in values of all-weather parameters recorded in Verona between days with &ltHealth Policy1 km/h increase in wind speed and day with rainfall were independently associated with 1.0%Significant differencehumidityUnivariateOutbreakHumidityand inversely correlated with meanmean wind speed and number of days with rainfall. Days of lockdownwhile information on daily weather parameters in the same area was downloaded from IlMeteo websitetesting policies and hospital preparedness should be reinforced during periods of higher meteorological risk and in local environments with adverse climate conditions.Background: Although evidence is accumulating that climate conditions may positively or negatively influence the scale of coronavirus disease 2019 (COVID-19) outbreaks0.3%uncertainty remains concerning the real impact of climate factors on viral transmission. Methods: The number of new daily cases of COVID-19 diagnosed in Verona (Italy) was retrieved from the official website of Veneto RegionGeography100 or ≥100 new daily COVID-19 diagnoses. Conclusions: Climate conditions may play an essential role in conditions of viral transmissionAir temperaturemean wind speed and number of days with rainfall remained significantly associated in multivariate analysis. The four weather parameters contributed to explaining 61% of variance in new daily COVID-19 diagnoses. Each 1% increase in air temperatureBackground: Although evidence is accumulating that climate conditions may positively or negatively influence the scale of coronavirus disease 2019 (COVID-19) outbreaks uncertainty remains concerning the real impact of climate factors on viral transmission. Methods: The number of new daily cases of COVID-19 diagnosed in Verona (Italy) was retrieved from the official website of Veneto Region while information on daily weather parameters in the same area was downloaded from IlMeteo website a renowned Italian technological company specialized in weather forecasts. The search period ranged between March 1 and November 11 2020. The number of new daily COVID-19 cases and meteorological data in Verona were correlated using both univariate and multivariate analysis. Results: The number of daily COVID-19 diagnoses in Verona was positively associated with the number of days in lockdown and humidity and inversely correlated with mean min and max temperature mean wind speed and number of days with rainfall. Days of lockdown mean air temperature humidity mean wind speed and number of days with rainfall remained significantly associated in multivariate analysis. The four weather parameters contributed to explaining 61% of variance in new daily COVID-19 diagnoses. Each 1% increase in air temperature 1% decrease in humidity 1 km/h increase in wind speed and day with rainfall were independently associated with 1.0% 0.3% 1.2% and 5.4% reduction in new COVID-19 daily diagnoses. A significant difference was observed in values of all-weather parameters recorded in Verona between days with <100 or ≥100 new daily COVID-19 diagnoses. Conclusions: Climate conditions may play an essential role in conditions of viral transmission and influence the likelihood or course of local COVID-19 outbreaks. Preventive measures testing policies and hospital preparedness should be reinforced during periods of higher meteorological risk and in local environments with adverse climate conditions.DemographyJournal of Hospital Management and Health Policy
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Temporal variability analysis reveals biases in electronic health records due to hospital process reengineering interventions over seven years

2019

[EN] Objective To evaluate the effects of Process-Reengineering interventions on the Electronic Health Records (EHR) of a hospital over 7 years. Materials and methods Temporal Variability Assessment (TVA) based on probabilistic data quality assessment was applied to the historic monthly-batched admission data of Hospital La Fe Valencia, Spain from 2010 to 2016. Routine healthcare data with a complete EHR was expanded by processed variables such as the Charlson Comorbidity Index. Results Four Process-Reengineering interventions were detected by quantifiable effects on the EHR: (1) the hospital relocation in 2011 involved progressive reduction of admissions during the next four months, (2) th…

Multivariate analysisData managementPsychological interventionElectronic Medical Records02 engineering and technologyGeographical locationsDatabase and Informatics Methods0302 clinical medicineMathematical and Statistical TechniquesHealth care0202 electrical engineering electronic engineering information engineeringCIENCIAS DE LA COMPUTACION E INTELIGENCIA ARTIFICIALMedicine and Health Sciences03.- Garantizar una vida saludable y promover el bienestar para todos y todas en todas las edadesElectronic Health Records030212 general & internal medicineData ManagementMultidisciplinaryQStatisticsRHospitalsPatient Discharge3. Good healthEuropePhysical SciencesMedicineEngineering and TechnologyMedical emergencyRelocationMATEMATICA APLICADAManagement EngineeringResearch ArticlePatient TransferComputer and Information SciencesScienceMEDLINESurgical and Invasive Medical ProceduresHealth InformaticsResearch and Analysis Methods03 medical and health sciencesBias020204 information systemsmedicineHumansEuropean UnionStatistical MethodsQuality of Health CareProtocol (science)Business Process Reengineeringbusiness.industrymedicine.diseaseHealth CareHealth Care FacilitiesSpainData qualityFISICA APLICADAMultivariate AnalysisPeople and placesbusinessMathematicsPLoS ONE
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Assessment of blood pressure early morning rise

2002

Myocardial InfarctionAssessment and DiagnosisDrug Administration ScheduleMedical RecordsInternal MedicineHumansMedicineWakefulnessLife StyleAntihypertensive AgentsMorningAdvanced and Specialized Nursingbusiness.industryIncidenceBlood Pressure DeterminationGeneral MedicineBlood Pressure Monitoring AmbulatoryCircadian RhythmSelf CareStrokeDeath Sudden CardiacBlood pressureAnesthesiaHypertensionDisease SusceptibilitySleepCardiology and Cardiovascular MedicinebusinessBlood Pressure Monitoring
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