Search results for "REE"

showing 10 items of 13625 documents

Decagram-Scale Synthesis of Multicolor Carbon Nanodots: Self-Tracking Nanoheaters with Inherent and Selective Anticancer Properties

2022

Carbon nanodots (CDs) are a new class of carbon-based nanoparticles endowed with photoluminescence, high specific surface area, and good photothermal conversion, which have spearheaded many breakthroughs in medicine, especially in drug delivery and cancer theranostics. However, the tight control of their structural, optical, and biological properties and the synthesis scale-up have been very difficult so far. Here, we report for the first time an efficient protocol for the one-step synthesis of decagram-scale quantities of N,S-doped CDs with a narrow size distribution, along with a single nanostructure multicolor emission, high near-infrared (NIR) photothermal conversion efficiency, and sel…

theranosticsMolecular StructureCell SurvivalInfrared RaysOptical ImagingAntineoplastic AgentsBiocompatible Materialstargeted cancer therapyCarbonCell Linemulticolor emissionMaterials TestingHumansNanoparticlesGeneral Materials Sciencecarbon nanodotshigh yield synthesisDrug Screening Assays AntitumorReactive Oxygen SpeciesCell Proliferation
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Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo[ b ]thiophene derivatives

2014

A new series of 3-benzoylamino-5-imidazol-5-yl-benzo[b]thiophenes and the parent amino derivatives were synthesized and screened as antitumor agents. All tested compounds showed concentration-dependent antiproliferative activity profile against HeLa cell line, exhibiting GI50 values in the low micromolar range. The most active compounds were tested in cell cycle perturbation experiments. A rapid accumulation of cells in the G2/M phase, with a concomitant reduction of cells in both the S and G0/G1 phases, was observed, suggesting that cell exposure to selected derivatives produces mitotic failure. To rationalize the biological results, the 3-benzoylamino-benzo[b]thiophenes were analyzed thro…

thiopheneVLAK protocolStereochemistryIn silicoCellAntineoplastic AgentsMechanism of actionHeLa CellHeLaAntineoplastic AgentStructure-Activity Relationship3-Benzoylamino-5-imidazol-4-yl-benzo[b]Settore BIO/10 - BiochimicaDrug DiscoverymedicineHumansMoietyComputer SimulationMitosisCell ProliferationPharmacologyAntitumor agentsbiologyDose-Response Relationship DrugMolecular StructureChemistryDrug Discovery3003 Pharmaceutical ScienceMedicine (all)Cell CycleOrganic ChemistryAntitumor agentG2/M phaseGeneral MedicineSettore CHIM/06 - Chimica OrganicaHeLa cell linebiology.organism_classificationSettore CHIM/08 - Chimica Farmaceuticamedicine.anatomical_structureCell cultureSettore CHIM/03 - Chimica Generale E InorganicathiophenesAntimitotic AgentTopoisomerase-II InhibitorDrug Screening Assays AntitumorHeLa CellsHuman
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Gas-liquid-solid operation of a Long Draft Tube Self-ingesting Reactor (LDTSR)

2008

Gas-liquid stirred vessels are widely employed to carry out chemical reactions involving a gas reagent and a liquid phase. The usual way for introducing the gas stream into the liquid phase is through suitable distributors placed below the impeller. An interesting alternative is that of using “self ingesting” vessels where the headspace gas phase is injected and dispersed into the vessel through suitable surface vortices. In this work the performance of a Long Draft Tube Self-ingesting Reactor dealing with gas-liquid-solid systems, is investigated. Preliminary experimental results on the effectiveness of this contactor for particle suspension and gas-liquid mass transfer performance in pres…

three phase systemSettore ING-IND/25 - Impianti Chimicigas-liquid-solidmass transferself-inducing
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Mass transfer and hydrodynamic characteristics of a Long Draft Tube Self-ingesting Reactor (LDTSR) for gas-liquid-solid operations

2011

Gas-liquid stirred vessels are widely employed to carry out chemical reactions involving a gas reagent and a liquid phase. The usual way for introducing the gas stream into the liquid phase is through suitable distributors placed below the impeller. An interesting alternative is that of using “self ingesting” vessels where the headspace gas phase is injected and dispersed into the vessel through suitable surface vortices. In this work the performance of a Long Draft Tube Self-ingesting Reactor dealing with gas-liquid-solid systems, is investigated. Preliminary experimental results on the effectiveness of this contactor for particle suspension and gas-liquid mass transfer performance in pres…

three phase systemSettore ING-IND/25 - Impianti Chimicigas-liquid-solidself-inducing reactors
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On the effectiveness of numerical simulation in the prediction of profile distorsion in extrusion

2005

three-dimensional extrusion numerical simulations die alignment
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Testing and Modeling of Hybrid Steel-Trussed Concrete Beams in Shear

2014

three-point bending teststress transferring mechanismhybrid steel trussed-concrete beams; push-out tests; shear connection; stress transferring mechanism; three-point bending tests; shear resistance; size effect; finite element modeling; analytical modelingthree-point bending testsfinite element modelinghybrid steel trussed-concrete beamspush-out testanalytical modelingshear resistancehybrid steel trussed-concrete beamSettore ICAR/09 - Tecnica Delle Costruzionisize effectpush-out testsshear connection
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Käydään juttukauppaa : freelancerin ja ostajan kohtaamisia journalismin kauppapaikalla

2011

tiedotustutkimustyösuhdeammatillistuminenlaadullinen tutkimushinnoittelustory businesstoimeksiantotyönkuvabuyersasiakassuhdepricingotantaviestintätutkimustyökulttuurijournalistinen tekstifreelancersSuomen Journalistiliittojournalistinen työprosessityösopimuksetyrittäjyysjournalistic working processdiskurssianalyysimarketplace of a journalismtekijänoikeusfreelance-työntekijätjournalismi
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Yhteisöllinen objektiivisuus : tiedon kohtalo Helen E. Longinon teoriassa

2009

tieteenfilosofiaobjektiivisuuspluralismitietoteoriateoreettinen filosofiaLongino Helen E
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Effect of ligand-binding on protein function

2014

tietokonesimulointifilamiinitliganditsitoutuminenionotrooppiset glutamaattireseptoritfilaminpeptidiliganditmolecular dynamicsionotropic glutamate receptorlääkesuunnitteluFLNaiGluRlaskennallinen tiedelaskennalliset menetelmätmolekyylidynamiikkaTCPTPsimulointiproteiinitbinding free energyT-cell protein tyrosine phosphatase
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Tiger nut powder as ingredient for obtaining gluten free foods based on noodle processing and extrusion technology

2021

Tiger nut (Cyperus esculentus L.) is a sweet tuber mostly cultivated in Eastern Spain (Valencia) and in west Africa. Its nutritional profile stands out for the high fiber and unsaturated fat content; moreover, the moderate protein amount might make it suitable for the nutritional enrichment of gluten free foods. The objective of this thesis was to extend the applications of tiger nut as gluten free (GF) ingredient in noodles making and snacks. The study of marketed GF pasta revealed the nutritional inadequacy and lower cooking performances compared with their gluten containing homologous. The quantification of furosine content was handy for a better understanding of the heat damage caused d…

tiger nutpastaextrusiongluten freeUNESCO::CIENCIAS MÉDICASfungidigestive oral and skin physiologyfood and beverages:CIENCIAS MÉDICAS [UNESCO]snacksnoodles
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