Search results for "REGENERATION"
showing 10 items of 889 documents
Integrated Urban Regeneration – Solution for Cities Revitalize
2013
Abstract To overcome the crisis which present society faces, it's necessary find solutions, adopt new strategies, leading to transforming too and revitalizing urban areas. Urban regeneration means the improvement the quality of life and investing in the future, this action being a very broad one, continues, difficult, but not impossible, in any case imperative.This paper presents the results of a study on integrated sustainable urban regeneration in several European countries, including Romania, and comparison between these countries in terms of urban regeneration.
Urban Regeneration in Porto: exploring the role of the EU urban policies in Bairro da Sé
European cities have been threatened by many challenges, including socioeconomic crisis, environmental hazards and the phenomenon of climate change, that affect both the territory and the people that inhabit it. At the same time the European Commission underlines the major impact of local urban settings on the sustainable development of Europe, while cities hold the capacity to steer their futures. Since the 1990s that the European Union, together with the Portuguese urban policies, have been influencing the processes of spatial development within the city of Porto by deploying direct and indirect urban regeneration strategies. Among these strategies are integrated urban regeneration interv…
CULTURE, SUSTAINABLE URBAN DEVELOPMENT AND URBAN REGENERATION
2014
Concerns about the conflict between economy, development on one hand and urban cultural heritage on the other hand, have made the urban development to be lately one of the most important themes at European level. Also, another issue of concern is social equity, aiming to strike a balance between economic development and equal access to culture for all generations of inhabitants of urban communities. Basically, ensuring these balances between urban cultural heritage, economy and social equity we express the essence of the concept of sustainable development from the perspective of culture. Urbanization is an ongoing process in all the cities of the world, but urban cultural heritage is a cru…
A Territorial Approach to the Production of Urban and Rural Landscape.
2018
The authors, starting from the examination of the historic data of Palermo landscapes on the south-east side, draws up an analysis of the landscape by illustrating the environmental characteristics and the intervention of man in its transformations. Therefore, determined by a certain point to refer to, the author, on the basis of archival, literary, and existing graphic documentation, has therefore sought to illustrate the evolution of the landscape in the geographical area of Maredolce while still presenting relations with the territory of Palermo. Examining the diaries at the end of the eighteenth century with the help of the water colored planks of the sites taking into account the great…
Macrophages as an Emerging Source of Wnt Ligands: Relevance in Mucosal Integrity
2019
The Wnt signaling pathway is a conserved pathway involved in important cellular processes such as the control of embryonic development, cellular polarity, cellular migration, and cell proliferation. In addition to playing a central role during embryogenesis, this pathway is also an essential part of adult homeostasis. Indeed, it controls the proliferation of epithelial cells in different organs such as intestine, lung, and kidney, and guarantees the maintenance of the mucosa in physiological conditions. The origin of this molecular pathway is the binding between Wnt ligands (belonging to a family of 19 different homologous secreted glycoproteins) and their specific membrane receptors, from …
Comparison of Immunosuppressive and Angiogenic Properties of Human Amnion-Derived Mesenchymal Stem Cells between 2D and 3D Culture Systems
2019
The secretion of potential therapeutic factors by mesenchymal stem cells (MSCs) has aroused much interest given the benefits that it can bring in the field of regenerative medicine. Indeed, the in vitro multipotency of these cells and the secretive capacity of both angiogenic and immunomodulatory factors suggest a role in tissue repair and regeneration. However, during culture, MSCs rapidly lose the expression of key transcription factors associated with multipotency and self-renewal, as well as the ability to produce functional paracrine factors. In our study, we show that a three-dimensional (3D) culture method is effective to induce MSC spheroid formation, to maintain the multipotency an…
Territori marginali e finestre di opportunità. Norcia tra gli eventi sismici del 1979 e del 2016
2021
Il contributo intende indagare la stretta connessione tra disastri naturali e traiettorie di sviluppo territoriale e come queste ultime siano determinate in larga parte dalle politiche pubbliche messe in atto nella fase post-emergenziale. A seguito dei disastri, il dibattito pubblico e politico, i grandi investimenti, la possibilità di operare trasformazioni urbanistiche possono generare uno scenario di opportunità e rinascita definibile come «window of opportunity». Si prende qui in considerazione l’evento sismico del 1979 di Norcia, insieme al relativo processo di ricostruzione, avviato assieme a un piano di rinascita economica incentrato sulle vocazioni locali e capace di frenare le tend…
Collective Locomotion of Human Cells, Wound Healing and Their Control by Extracts and Isolated Compounds from Marine Invertebrates
2020
The collective migration of cells is a complex integrated process that represents a common theme joining morphogenesis, tissue regeneration, and tumor biology. It is known that a remarkable amount of secondary metabolites produced by aquatic invertebrates displays active pharmacological properties against a variety of diseases. The aim of this review is to pick up selected studies that report the extraction and identification of crude extracts or isolated compounds that exert a modulatory effect on collective cell locomotion and/or skin tissue reconstitution and recapitulate the molecular, biochemical, and/or physiological aspects, where available, which are associated to the substances und…
Cartilage Regeneration and Tissue Engineering
2019
Abstract Articular cartilage in synovial joints is a hyaline cartilage highly hydrated with a rigorous order of cells and fibers and a specific content of proteoglycans and glycoproteins. It provides a low-friction surface, participates in the lubrication of the synovial joints, and distributes the forces to the underlying bone. It is an avascular and aneural tissue where small metabolites diffuse to and from cells. Unlike hyaline cartilage in other locations, articular cartilage lacks perichondrium, a layer of fibrous tissue around it that serves as the source of new cartilage cells. Thus, although extracellular matrix undergoes continuous remodeling throughout life, the ability to repair …