Search results for "REGION"

showing 10 items of 4910 documents

Are the new genetic tools for diagnosis of Wilson disease helpful in clinical practice?

2020

Summary The diagnosis of Wilson disease is not always easy. For many patients, a combination of tests reflecting disturbed copper metabolism may be needed. Testing for ATP7B variants has become part of the routine diagnostic approach. The methods of genetic testing include analysis of the 21 coding exons and intronic flanking sequences, in which exons with recurrent variants would be prioritised depending on the mutation frequency in the local population. If sequencing the entire ATP7B gene cannot identify 2 variants and the suspicion for Wilson disease is high, after reviewing the clinical data, WES (whole-exome sequencing) or WGS (whole-genome sequencing) could be applied. A workflow base…

DiseaseReviewIndian childhood cirrhosisBioinformaticsDNA sequencingWES whole-exome sequencingPFIC progressive familial intrahepatic cholestasisInternal MedicinemedicineImmunology and AllergyMultiplex ligation-dependent probe amplificationWGS whole-genome sequencingExome sequencingGenetic testingWilson diseaseWhole genome sequencingWhole-genome sequencingHepatologymedicine.diagnostic_testMEDNIK syndromebusiness.industryCopper metabolismGastroenterologyMLPA multiplex ligation-dependent probe amplificationmedicine.diseaseICC Indian childhood cirrhosisNGS next-generation sequencingDMR differentially methylated regionsWhole-exome sequencingNext-generation sequencingbusinessICT idiopathic or primary copper toxicosisCDG congenital disorders of glycosylationGenetic diseasesJHEP Reports
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Distritos industriales y renta económica: el efecto distrito – renta

2019

En el presente trabajo se expone una primera aproximación al efecto distrito desde la variable de la renta económica, lo que se ha denominado efecto distrito – renta. Esta aproximación al fenómeno distritural se realiza desde la perspectiva del desarrollo local neomarshalliano para enfatizar la centralidad del distrito industrial como fuente de interpretaciones propias sobre el cambio económico y sujeto activo del mismo. A nivel empírico se realiza una aproximación a la contrastación de la existencia o no de efecto distrito – renta en los distritos industriales españoles para el año 2013; estos datos son analizados a través de la comparativa de la renta total, per cápita y por ocupado expre…

Distritos industrialesmedia_common.quotation_subjectWelfare economicsLocal DevelopmentEconomic rentTotal incomelcsh:HD72-88Industrial districtlcsh:Economic growth development planningefecto distritoGeographysistemas locales de trabajoPer capitalcsh:H1-99Desarrollo económicoEconomía industrialpequeñas y medianas empresaslcsh:Social sciences (General)Economía regionalEconomic changemedia_commonPapeles de Europa
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Regional Income Inequality in Spain 1860–2015

2018

How has regional economic inequality evolved since 1860? Is there a relationship between initial per-capita income and regional growth rates? Is there any relation between the evolution of regional inequality and the economic development process in Spain? In order to answer these questions, a number of different indicators of inequality are offered in this chapter. Then the patterns of convergence or divergence followed by Spanish regions from the mid-nineteenth century to the present are studied. Regional income inequality rose in the early stages of economic development and then declined. However, with high levels of development, around the 1980s, a change of trend is observed. In other w…

Divergence (linguistics)Inequality060106 history of social sciencesmedia_common.quotation_subject0211 other engineering and technologies021107 urban & regional planningConvergence (economics)06 humanities and the arts02 engineering and technologyEconomic inequalityOrder (exchange)Economics0601 history and archaeologyDemographic economicsRegional incomemedia_common
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Biological quality metrics: their variability and appropriate scale for assessing Streams

2006

The concept of spatial scale is at the research frontier in ecology, and although focus has been placed on trying to determine the role of spatial scale in structuring communities, there still is a further need to standardize which organism groups are to be used at which scale and under which circumstances in environmental assessment. This paper contributes to the understanding of the variability at different spatial scales (reach, stream, river basin) of metrics characterizing communities of different biological quality elements (macrophytes, fishes, macroinvertebrates and benthic diatoms) as defined by the Water Framework Directive. For this purpose, high-quality reaches from medium-sized…

Diversity indexgeographygeography.geographical_feature_categoryEcoregionWater Framework DirectiveBenthic zoneEcologySpatial ecologyDrainage basinBiodiversityEnvironmental scienceMacrophyte
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Path dependence and landscape: initial conditions, contingency and sequences of events in latgale, latvia

2013

AbstractThe notion of path dependence has not yet been well explored as a tool for analysing landscape change. Within geography it is primarily economic geographers who have, up until now, shown a keen interest in this concept which stresses the role of social agency and institutions in understanding the development trajectories of regions. Further, the notion of path dependence usefully captures the idea of contingency in historical sequences. This article presents such a perspective on landscape change analysis, discussing two dominant types of sequences in path‐dependent systems. Self‐reinforcing sequences characterize the formation and long‐term reproduction of a given institutional pat…

Dominant typesLandscape changeReproduction (economics)05 social sciencesGeography Planning and DevelopmentPerspective (graphical)0211 other engineering and technologies0507 social and economic geography021107 urban & regional planning02 engineering and technologySociologyEconomic geographySocial scienceContingency050703 geographyPath dependenceGeografiska Annaler: Series B, Human Geography
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Simultaneous bilateral occurrence of a M. extensor digiti medii and a M. extensor digitorum brevis.

1993

Summary For the first time, the simultaneous and bilateral occurrence of two variants of the extensors of the fingers, M. extensor digiti medii and M. extensor digitorum brevis, is reported. The extensor of the middle finger arises from the distal fourth of the radius and runs to the base of the proximal phalanx. The short extensor of the fingers arises from the metacarpal region and inserts into the dorsal aponeurosis. Both muscles are innervated by the R. profundus n. radialis.

DorsumExtensor digitorum brevisProximal phalanxMetacarpal regionMusclesGenetic VariationGeneral MedicineAnatomyBiologyMiddle fingermusculoskeletal systembody regionsFingersmedicine.anatomical_structuremedicineM. extensor digitorum brevisHumansAponeurosisFemaleAnatomyDevelopmental BiologyAgedAnnals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft
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Revision of the plant bug genus Xenocylapidius (Hemiptera, Heteroptera, Miridae, Cylapinae), with descriptions of five new species from Australia and…

2014

Abstract The genus Xenocylapidius Gorczyca, 1997 is revised. Five new species: Xenocylapidius acutipennis sp. n., Xenocylapidius ater sp. n., Xenocylapidius bimaculatus sp. n., Xenocylapidius gemellus sp. n., and Xenocylapidius rolandi sp. n. are described from Australia and New Caledonia. Illustrations of the male genitalia, color photographs of dorsal and lateral views of the adults of all species, and key to species of the genus Xenocylapidius are provided.

DorsumInsectaCylapinaeArthropodaMiridaeMiridaeCylapinaeMale genitaliaZoologyReview ArticleBiologyAustralian RegionHemipteraHeteropteraXenocylapidiusNew Caledonialcsh:ZoologyMiroideaAnimalialcsh:QL1-991Ecology Evolution Behavior and Systematicsnew speciesHemipteraHeteropteraAnimaliaHeteropteraAustraliaCylapinaebiology.organism_classificationHemipteraMiridaeKey (lock)Animal Science and ZoologyTaxonomy (biology)keysMiridaeXenocylapidiusAnimalia
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Osteocondroma solitario de la escápula: localización poco habitual para un tumor frecuente

2021

Osteochondroma is a benign bone tumor that usually affects children and young adults. It is typically located in the metaphysis of long bones around the knee, although it could also affect flat bones like scapula. We report the case of a 11-year-old child with one year of evolution painful tumor at the dorsal surface of the scapula. He was diagnosed with osteochondroma of the scapula, uncommon location for this tumor. Due to the persistence of the symptomatology surgical excision was performed.

DorsumOsteochondromaSolitary Osteochondromabusiness.industryAnatomyMetaphysismusculoskeletal systemmedicine.diseasebody regionsmedicine.anatomical_structureScapulaPediatrics Perinatology and Child HealthMedicineSurgical excisionbusinessArchivos Argentinos de Pediatria
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La distribuzione dell'attività proteasica nella blastula e nella giovane gastrula diDiscoglossus pictus

1956

Summary Protease activity has been measured in the animal and vegetal half of the blastula and in the dorsal and ventral regions of the early gastrula of Discoglossus pictus. A higher protease activity was found in the dorsal region of the early gastrula, where presumptive chordamesoderm and presumptive neuroectoderm are localized.

Dorsumanimal structuresNeuroectodermAnatomyBiologyBlastulabiology.organism_classificationMolecular biologyGastrulationChordamesodermDorsal regionembryonic structuresDiscoglossusAnimal Science and ZoologyBolletino di zoologia
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Differences in conspicuousness between alternative color morphs in a polychromatic lizard

2015

In polychromatic species, differences in conspicuousness among alternative color morphs may affect the costs and benefits relating to signal detectability by primary receivers and unintended observers. Using visual modeling, we studied the conspicuousness of the body coloration in a ventrally polychromatic population of common wall lizards (Podarcis muralis). This species shows a complex color pattern that combines brown dorsal coloration, long-wavelength–biased ventral coloration, and ventrolateral ultraviolet (UV)-blue patches that are used to signal male quality. Considering simultaneously the visual system of P. muralis and lizard predators, we quantified the chromatic and achromatic (i…

Dorsumeducation.field_of_studygenetic structuresbiologyEcologyLizardPopulationZoologybiology.organism_classificationPredationPodarcis muralisbiology.animalAnimal Science and ZoologyBody regionChromatic scaleeducationPredatorEcology Evolution Behavior and SystematicsBehavioral Ecology
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