Search results for "REGION"

Investigating the role of environmental taxes and regulations for renewable energy consumption: evidence from developed economies

2021

The current study aims to explore the role of environmental taxes and regulations for the renewable energy consumption, focusing on reporting policy suggestions to overcome climate change issues and achieve environmental sustainability. The main objective of this paper is to examine the relation between renewable energy, environmental taxes, environmental technologies, and environmental regulations in 29 OECD countries during 1996–2018. More precisely, we inspect the impact of the environmental regulations and environmental technologies on the renewable energy consumption. The authors employ CIPS and CADF unit root tests, panel Westerlund co-integration test, FMOLS, and Quantile regression …

Delayed chronic intracranial subdural hematoma complicating resection of a tanycytic thoracic ependymoma

2015

Background To demonstrate that the diagnosis of an intracranial subdural hematoma should be considered for patients presenting with acute or delayed symptoms of intracranial pathology following resection of a spinal tumor. Case description We present a case of a 57-year-old woman found to have a chronic subdural hematoma 1 month following resection of a thoracic extramedullary ependymoma. Evacuation of the hematoma through a burr hole relieved the presenting symptoms and signs. Resolution of the hematoma was confirmed with a computed tomography (CT) scan. Conclusion Headache and other symptoms not referable to spinal pathology should be regarded as a warning sign of an intracranial subdural…

Dural sac localization using myelography and its application to the lumbosacral epidural in dogs

2020

Background: The techniques described for the identification of the lumbosacral (LS) epidural space in dogs do not guarantee the needle position or an accidental subarachnoid puncture, especially in small size dogs.Aim: To determine the relationship between body weight and the location of the dural sac (DS) using myelography in dogs, and to determine the possibility of subarachnoid puncture during LS epidural based on the position of the DS.Methods: Four masked observers evaluated 70 myelographic studies of dogs, annotating the vertebrae where the DS ended, if it was localized before or after the LS space, and if accidental subarachnoid puncture during LS epidural injection was possible (yes…

Recommendations for a nomenclature system for reporting methylation aberrations in imprinted domains

2018

The analysis of DNA methylation has become routine in the pipeline for diagnosis of imprinting disorders, with many publications reporting aberrant methylation associated with imprinted differentially methylated regions (DMRs). However, comparisons between these studies are routinely hampered by the lack of consistency in reporting sites of methylation evaluated. To avoid confusion surrounding nomenclature, special care is needed to communicate results accurately, especially between scientists and other health care professionals. Within the European Network for Human Congenital Imprinting Disorders we have discussed these issues and designed a nomenclature for naming imprinted DMRs as well …

Genome-wide promoter methylation analysis in neuroblastoma identifies prognostic methylation biomarkers.

2012

Background: Accurate outcome prediction in neuroblastoma, which is necessary to enable the optimal choice of risk-related therapy, remains a challenge. To improve neuroblastoma patient stratification, this study aimed to identify prognostic tumor DNA methylation biomarkers.Results: To identify genes silenced by promoter methylation, we first applied two independent genome-wide methylation screening methodologies to eight neuroblastoma cell lines. Specifically, we used re-expression profiling upon 5-aza-2'-deoxycytidine (DAC) treatment and massively parallel sequencing after capturing with a methyl-CpG-binding domain (MBD-seq). Putative methylation markers were selected from DAC-upregulated …

A propósito del "Programa de ordenacion y promocion de agricultura de montaña" del Alto Mijares y Alto Palancia (Castellón)

1990

Cada vez es mayor el grado de concienciacion social y politico sobre la problematica de las zonas desfavorecidas en españa. En la comunidad valenciana, el programa de ordenacion y promocion del alto mijares y alto palancia es el primer documento aprobado oficialmente por el gobierno regional que, en el marco de la ley de agricultura de montaña, pretende constituirse en la base de las actuaciones tendentes a hacer frente a la dinamica reciente de estas zonas desfavorecidas. En este articulo se hace un analisis critico de algunas de las aportaciones mas destacables desde la optica de la geografia. (a)

The Role of Geographic Technologies in the Measure of Spatial Equity. Twenty-First Century Solutions for Old Geographical Issues

2019

In Western societies, the development of the Welfare State has been accompanied by the proposal of different models of spatial organisation that help to improve spatial equity, this being a priority object of all public policy because it clearly contributes to the achievement of a greater social cohesion. Geography has contributed, from Christaller to the present, to propose territorial models that help to optimise the location of activities and services, using spatial statistics and digital cartography. At present, the study of spatial equity is again receiving the attention of the academy, in particular as regards the provision of public services and facilities in urban and metropolitan a…

Regional analysis of soil erodibility in Sicily

2007

Crucial role of aspartic acid at position 265 in the CH2 domain for murine IgG2a and IgG2b Fc-associated effector functions.

2008

Abstract Replacement of aspartic acid by alanine at position 265 (D265A) in mouse IgG1 results in a complete loss of interaction between this isotype and low-affinity IgG Fc receptors (FcγRIIB and FcγRIII). However, it has not yet been defined whether the D265A substitution could exhibit similar effects on the interaction with two other FcγR (FcγRI and FcγRIV) and on the activation of complement. To address this question, 34-3C anti-RBC IgG2a and IgG2b switch variants bearing the D265A mutation were generated, and their effector functions and in vivo pathogenicity were compared with those of the respective wild-type Abs. The introduction of the D265A mutation almost completely abolished the…

Reactivación participativa del espacio público. Estudios de caso en Valencia y Madrid

2017

[EN] This work aims to understand the phenomenon of what we have propose to call "participatory reactivation of public space", which is characterized by the direct participation of citizens in the creation and management of social and cultural activities in public spaces, as part of a general will to reclaim that space as truly "public", where the citizens have power in the decision-making processes. This movement has been reinforced by the establishment of professional collectives and initiatives from public institutions. Seven case studies of organizations from Valencia and Madridwere conducted, in the form of semi-structured in-depth interviews,in order to define the shared characteristi…