Search results for "REGIONS"

Evolution of Tourist Accommodation Structures in Romanian's Developing Regions in the Context of New Challenges at European Level

2013

Abstract This paper analyzes the evolution of tourist structures with functions of tourist accommodation in the eights development regions of Romania Romania. Given the financial crisis, the differences between regions in terms of tourism infrastructure have accentuated. Investments to modernize tourist infrastructure and resorts can certainly revive tourism in many regions, which in its turn can help the economic growth of the area.

Measuring spatial concentration: A transportation problem approach

2019

This paper will propose an index for measuring spatial concentration, which is based on the solution of a particular transportation problem. This approach extends a new index proposed for the measurement of seasonality to the spatial case, and it takes into account the level of the concentration of the phenomenon of interest according to its spatial distribution. Various properties of the proposed index, which make it a desirable measure for spatial concentration, will also be described. An empirical application, using data from selected European countries, will be provided, and the results derived from the proposed index will be compared with those derived from currently used indices. Este…

THe Verdoorn law at regional level: Evidence from Europe

2014

Weighting non-covalent forces in the molecular recognition of C60. Relevance of concave–convex complementarity

2008

The relative contributions of several weak intermolecular forces to the overall stability of the complexes formed between structurally related receptors and [60]fullerene are compared, revealing a discernible contribution from concave–convex complementarity. Viruela Martin, Pedro Manuel, Pedro.M.Viruela@uv.es ; Viruela Martin, Rafael, Rafael.Viruela@uv.es ; Orti Guillen, Enrique, Enrique.Orti@uv.es

The cyclopentenone-type prostaglandin 15-deoxy-delta12,14-prostaglandin J2 inhibits CD95 ligand gene expression in T lymphocytes: interference with p…

2003

Abstract 15-Deoxy-Δ12,14-PGJ2 (15d-PGJ2) is a cyclopentenone-type PG endowed with anti-inflammatory properties and produced by different cells, including those of the immune system. 15d-PGJ2 is a natural ligand of the peroxisome proliferator-activated receptor (PPAR)-γ nuclear receptor, but relevant PPARγ-independent actions mediated by this prostanoid have been described. Fas (APO-1/CD95) and its ligand (Fas-L) are cell surface proteins whose interaction activates apoptosis of Fas-expressing targets. In T cells, the Fas-Fas-L system regulates activation-induced cell death and has been implicated in diseases in which lymphocyte homeostasis is compromised. Moreover, several studies have desc…

A second-order sparse factorization method for Poisson's equation with mixed boundary conditions

1992

Abstract We propose an algorithm for solving Poisson's equation on general two-dimensional regions with an arbitrary distribution of Dirichlet and Neumann boundary conditions. The algebraic system, generated by the five-point star discretization of the Laplacian, is solved iteratively by repeated direct sparse inversion of an approximating system whose coefficient matrix — the preconditioner — is second-order both in the interior and on the boundary. The present algorithm for mixed boundary value problems generalizes a solver for pure Dirichlet problems (proposed earlier by one of the authors in this journal (1989)) which was found to converge very fast for problems with smooth solutions. T…

REPLICATED TRIANGLE TESTS: EFFECT OF FEED-BACK AND PRODUCT COMPARISON ON PERFORMANCE

1998

The feed-back procedure consists of informing assessors of the quality of their response (correct or incorrect) after each triangle test. This procedure showed a contrasted effect according to assessors' detection abilities. A decrease in performance was observed for assessors who had low detection abilities whereas a slight increase was observed for assessors who had higher detection abilities. When the feed-back procedure is followed by a comparison by tasting of the two products, the increase in performance from the beginning to the end of the session is larger than that of both feed-back and control (no information) groups. We suggest that information inference from previous tests, whic…

Laparoscopic endopelvic sacral implantation of a Brindley controller for recovery of bladder function in a paralyzed patient

2008

Background: A number of techniques are being investigated to accomplish bladder control recovery in paralyzed patients using the neurostimulation, but currently, all techniques are based on the dorsal implantation of the electrodes using a laminectomy. Methods: On 27 April 2006 we performed a laparoscopic implantation of a Finetech-Brindley bladder controller on the endopelvic sacral roots in a Th8 completely paralyzed woman who had previously undergone the removal of a Brindley controller due to an arachnoiditis after extrathecal implantation with intradural sacral deafferentation. Results: We required about 3.5 h for the entire surgical procedure; no complications occurred and the patient…

Spatial and sectoral effects on firm entry and exit. Evidence from Italy.

2012

Nanog Regulates Primordial Germ Cell Migration Through Cxcr4b

2010

Abstract Gonadal development in vertebrates depends on the early determination of primordial germ cells (PGCs) and their correct migration to the sites where the gonads develop. Several genes have been implicated in PGC specification and migration in vertebrates. Additionally, some of the genes associated with pluripotency, such as Oct4 and Nanog, are expressed in PGCs and gonads, suggesting a role for these genes in maintaining pluripotency of the germ lineage, which may be considered the only cell type that perpetually maintains stemness properties. Here, we report that medaka Nanog (Ol-Nanog) is expressed in the developing PGCs. Depletion of Ol-Nanog protein causes aberrant migration of …