Search results for "REGULATION"
showing 10 items of 4463 documents
The Developmental Transcriptome for Lytechinus variegatus Exhibits Temporally Punctuated Gene Expression Changes
2019
AbstractEmbryonic development is arguably the most complex process an organism undergoes during its lifetime, and understanding this complexity is best approached with a systems-level perspective. The sea urchin has become a highly valuable model organism for understanding developmental specification, morphogenesis, and evolution. As a non-chordate deuterostome, the sea urchin occupies an important evolutionary niche between protostomes and vertebrates.Lytechinus variegatus(Lv) is an Atlantic species that has been well studied, and which has provided important insights into signal transduction, patterning, and morphogenetic changes during embryonic and larval development. The Pacific specie…
Regulation of hdc expression and HDC activity by enological factors in lactic acid bacteria.
2008
Aims: The aim of this work was to study the influence of enological factors on the histidine decarboxylase gene (hdc) expression and on histidine decarboxylase enzyme (HDC) activity in Lactobacillus hilgardii, Pediococcus parvulus and Oenococcus oeni. Methods and Results: Cell extracts and whole cells were used. Glucose, fructose, malic acid and citric acid diminished the hdc expression. Ethanol did not increase hdc expression or activity in cells, but increased HDC activity. Temperature and pH had effect on the activity of HDC but not on hdc expression. Tartaric acid and l-lactic acid, and sulphur dioxide (SO2) had no effect on enzyme synthesis and activity. Bacterial species differ in t…
Accounting in Identity Regulation : Producing the Appropriate Worker
2021
It is acknowledged that identity regulation in organizations relies on discursive resources. This study moves beyond discourse – illustrating how discourse and accounting measurements are mobilized together in revising identity. Measurement produces persistence, clarity, transparency and comparability, as well as direction: Accounting’s quantitative knowledge ‘amplifies’ discourse. We explain the Great Alliance between words and numbers in a case study addressing events in an organization’s transformation. This extends our understanding of what takes place on the interface between identity and accounting. peerReviewed
The endogenous retroviral insertion in the human complement C4 gene modulates the expression of homologous genes by antisense inhibition
2001
Intron 9 contains the complete endogenous retrovirus HERV-K(C4) as a 6.4-kb insertion in 60% of human C4 genes. The retroviral insertion is in reverse orientation to the C4 coding sequence. Therefore, expression of C4 could lead to the transcription of an antisense RNA, which might protect against exogenous retroviral infections. To test this hypothesis, open reading frames from the HERV sequence were subcloned in sense orientiation into a vector allowing expression of a beta-galactosidase fusion protein. Mouse L cells which had been stably transfected with either the human C4A or C4B gene both carrying the HERV insertion (LC4 cells), and L(Tk-) cells without the C4 gene were transiently tr…
The human autoantigen La/SS-B accelerates herpes simplex virus type 1 replication in transfected mouse 3T3 cells.
1998
SUMMARY Permanently transfected mouse cell lines which expressed different levels of the human autoantigen La/SS-B were infected with different strains of herpes simplex virus type 1, including the strains ANG, HSZP, 17syn+ and HFEM. During infection the localization of the human La protein was followed using an anti-La MoAb, which recognized only the human La protein but did not cross-react with either the endogenous mouse La protein or any viral encoded protein. After infection La protein was transported from the nucleus to the cytoplasm. The time course of translocation was dependent on the amount of human La protein expressed in the respective cell line. Moreover, acceleration of viral …
Teacher-child interaction quality and children's self-regulation in toddler classrooms in Finland and Portugal
2021
This study examines the association between teacher–child interaction quality and children's self‐regulation in Finnish and Portuguese toddler classrooms. The participants included 230 Finnish (M = 29; SD = 3 months) and 283 Portuguese (M = 30, SD = 4 months) toddlers and their teachers (n = 43 Finland; n = 29 Portugal). The children's behavioural self‐regulation (attention, working memory, and inhibition control) was individually tested, and the teachers evaluated the children's self‐regulation skills in the classroom. The quality of the teacher–child interactions (i.e., emotional and behavioural support and engaged support for learning) was evaluated using the CLASS‐Toddler observation in…
The role of the agreement as a tool for management of property relations in cases of cross border marriages and civil unions/partnerships registered …
2021
The essay examines the role of the agreement as a tool for managing property relationships in crossborder marriages and registered partnerships, in light of EU Regulations 1103 and 1104 of 2016, on the property regimes of international married or registered couples. The main prerogative of such acts is the recognition of the parties? freedom to choose the court and the applicable law. The law governing the matrimonial property regimes, or the property consequences of registered partnerships, has universal scope. This agreement in the form envisaged, which is backed by the need for legal certainty and predictability of the applicable rules, means that the spouses, in family problems which ha…
Socio-technical risk governance through dyadic risk dialogue : copper corrosion as a safety challenge in the geological disposal of spent nuclear fuel
2014
The risk of corrosion in oxygen-free water has become an issue of scientific controversy possibly even threatening the realisation of the final disposal of spent nuclear fuel in Finland and Sweden. In Sweden there has been extensive discussion about the issue since 2007, but only recently has this debate increased in Finland although the similar disposal concept (KBS-3) is applied in both countries. In this report, we analyse how the implementer, Posiva (a Finnish nuclear waste company), and the regulator, STUK (the Finnish Radiation and Nuclear Safety Authority), have been engaged in a dialogue on the risk of copper corrosion. For over thirty years the implementer and regulator have been e…
Deciding on the direction of career and life : personal goals, identity development, and well-being during the transition to adulthood
2017
Humans make efforts to manage their lives, and they do this by setting goals and making decisions. When they commit to their decisions, they construct their identity. This research aimed to study young people’s personal goal contents and appraisals, and how these constructs were related to identity and career identity development and subjective well-being. The theoretical basis of this research comprised the life-span model of motivation (Nurmi, 2004; Salmela-Aro, 2009), the conceptualisation of phase- adequate engagement (Dietrich, Parker, & Salmela-Aro, 2012), and the dual-cycle model of identity development (Luyckx, Goossens, Soenens, & Beyers, 2006; Luyckx et al., 2008). The data for th…
Modelling the influence of automaticity of behaviour on physical activity motivation, intention and actual behaviour
2014
In research and in practise social-cognitive models, such as the theory of planned behaviour (TPB), are used to predict physical activity behaviour. These models mainly focus on reflective cognitive processes. As a reflective process, intention is thought to be the most proximal predictor to behaviour. Nevertheless, research suggests that the relation between intention and actual behaviour, the so called intention-behaviour gap, is moderate. Many health-related actions in daily life are performed repetitively and with minimal forethought. In contrast to social-cognitive theories, dual-process theories suggest that behaviour is based on both reflective and automatic processes. Recent researc…